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Volumn 35, Issue 1, 2015, Pages 12-25

MicroRNAs in fatty liver disease

Author keywords

cirrhosis; fibrosis; noncoding RNA; steatohepatitis; steatosis

Indexed keywords

BIOLOGICAL MARKER; LIVER X RECEPTOR ALPHA; MICRORNA; MICRORNA 1; MICRORNA 107; MICRORNA 10B; MICRORNA 122; MICRORNA 128 2; MICRORNA 130A 3P; MICRORNA 155; MICRORNA 206; MICRORNA 21; MICRORNA 217; MICRORNA 24; MICRORNA 27; MICRORNA 27A; MICRORNA 27B; MICRORNA 30C; MICRORNA 33A; MICRORNA 33B; MICRORNA 34A; MICRORNA 613; MICRORNA 758; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84928543338     PISSN: 02728087     EISSN: 10988971     Source Type: Journal    
DOI: 10.1055/s-0034-1397345     Document Type: Article
Times cited : (39)

References (155)
  • 1
    • 80052433519 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis and new targets for therapy
    • Altamirano J., Bataller R. Alcoholic liver disease: pathogenesis and new targets for therapy. Nat Rev Gastroenterol Hepatol: 2011; 8 9 491 501
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , Issue.9 , pp. 491-501
    • Altamirano, J.1    Bataller, R.2
  • 2
    • 77952567110 scopus 로고    scopus 로고
    • Hepatitis C virus-induced steatosis: An overview
    • Negro F. Hepatitis C virus-induced steatosis: an overview. Dig Dis: 2010; 28 1 294 299
    • (2010) Dig Dis , vol.28 , Issue.1 , pp. 294-299
    • Negro, F.1
  • 3
    • 84884860377 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes
    • Birkenfeld A. L., Shulman G. I. Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology: 2014; 59 2 713 723
    • (2014) Hepatology , vol.59 , Issue.2 , pp. 713-723
    • Birkenfeld, A.L.1    Shulman, G.I.2
  • 4
    • 84880425040 scopus 로고    scopus 로고
    • Epidemiology and natural history of patients with NAFLD
    • Bhala N., Jouness R. I., Bugianesi E. Epidemiology and natural history of patients with NAFLD. Curr Pharm Des: 2013; 19 29 5169 5176
    • (2013) Curr Pharm des , vol.19 , Issue.29 , pp. 5169-5176
    • Bhala, N.1    Jouness, R.I.2    Bugianesi, E.3
  • 5
    • 84862883948 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease/steatohepatitis: Epidemiology, pathogenesis, clinical presentation and treatment
    • Milić S., Stimac D. Nonalcoholic fatty liver disease/steatohepatitis: epidemiology, pathogenesis, clinical presentation and treatment. Dig Dis: 2012; 30 2 158 162
    • (2012) Dig Dis , vol.30 , Issue.2 , pp. 158-162
    • Milić, S.1    Stimac, D.2
  • 6
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley B. Q., Calcagno C. J., Harrison S. A. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology: 2010; 51 5 1820 1832
    • (2010) Hepatology , vol.51 , Issue.5 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 7
    • 3543029821 scopus 로고    scopus 로고
    • Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
    • Samuel V. T., Liu Z. X., Qu X., et al. Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem: 2004; 279 31 32345 32353
    • (2004) J Biol Chem , vol.279 , Issue.31 , pp. 32345-32353
    • Samuel, V.T.1    Liu, Z.X.2    Qu, X.3
  • 8
    • 38649116056 scopus 로고    scopus 로고
    • Selective versus total insulin resistance: A pathogenic paradox
    • Brown M. S., Goldstein J. L. Selective versus total insulin resistance: a pathogenic paradox. Cell Metab: 2008; 7 2 95 96
    • (2008) Cell Metab , vol.7 , Issue.2 , pp. 95-96
    • Brown, M.S.1    Goldstein, J.L.2
  • 9
    • 84860455885 scopus 로고    scopus 로고
    • The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance
    • Farese R. V. Jr, Zechner R., Newgard C. B., Walther T. C. The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance. Cell Metab: 2012; 15 5 570 573
    • (2012) Cell Metab , vol.15 , Issue.5 , pp. 570-573
    • Farese, R.V.1    Zechner, R.2    Newgard, C.B.3    Walther, T.C.4
  • 11
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • Yates L. A., Norbury C. J., Gilbert R. J. The long and short of microRNA. Cell: 2013; 153 3 516 519
    • (2013) Cell , vol.153 , Issue.3 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 12
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell: 2004; 116 2 281 297
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 13
    • 80054971110 scopus 로고    scopus 로고
    • Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
    • Rayner K. J., Esau C. C., Hussain F. N., et al. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature: 2011; 478 7369 404 407
    • (2011) Nature , vol.478 , Issue.7369 , pp. 404-407
    • Rayner, K.J.1    Esau, C.C.2    Hussain, F.N.3
  • 14
    • 78049432896 scopus 로고    scopus 로고
    • Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice
    • Patrick D. M., Montgomery R. L., Qi X., et al. Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest: 2010; 120 11 3912 3916
    • (2010) J Clin Invest , vol.120 , Issue.11 , pp. 3912-3916
    • Patrick, D.M.1    Montgomery, R.L.2    Qi, X.3
  • 15
    • 84892573723 scopus 로고    scopus 로고
    • The multilayered complexity of ceRNA crosstalk and competition
    • Tay Y., Rinn J., Pandolfi P. P. The multilayered complexity of ceRNA crosstalk and competition. Nature: 2014; 505 7483 344 352
    • (2014) Nature , vol.505 , Issue.7483 , pp. 344-352
    • Tay, Y.1    Rinn, J.2    Pandolfi, P.P.3
  • 16
    • 84856008627 scopus 로고    scopus 로고
    • The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2
    • Young L. E., Moore A. E., Sokol L., Meisner-Kober N., Dixon D. A. The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2. Mol Cancer Res: 2012; 10 1 167 180
    • (2012) Mol Cancer Res , vol.10 , Issue.1 , pp. 167-180
    • Young, L.E.1    Moore, A.E.2    Sokol, L.3    Meisner-Kober, N.4    Dixon, D.A.5
  • 17
    • 84890205234 scopus 로고    scopus 로고
    • MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice
    • Horie T., Nishino T., Baba O., et al. MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice. Nat Commun: 2013; 4 2883
    • (2013) Nat Commun , vol.4 , pp. 2883
    • Horie, T.1    Nishino, T.2    Baba, O.3
  • 18
    • 84904739790 scopus 로고    scopus 로고
    • Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia
    • Ng R., Wu H., Xiao H., et al. Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. Hepatology: 2014; 60 2 554 564
    • (2014) Hepatology , vol.60 , Issue.2 , pp. 554-564
    • Ng, R.1    Wu, H.2    Xiao, H.3
  • 20
    • 84881541332 scopus 로고    scopus 로고
    • Inhibition of microRNA122 decreases SREBP1 expression by modulating suppressor of cytokine signaling 3 expression
    • Shibata C., Kishikawa T., Otsuka M., et al. Inhibition of microRNA122 decreases SREBP1 expression by modulating suppressor of cytokine signaling 3 expression. Biochem Biophys Res Commun: 2013; 438 1 230 235
    • (2013) Biochem Biophys Res Commun , vol.438 , Issue.1 , pp. 230-235
    • Shibata, C.1    Kishikawa, T.2    Otsuka, M.3
  • 21
    • 77952707662 scopus 로고    scopus 로고
    • MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism
    • Iliopoulos D., Drosatos K., Hiyama Y., Goldberg I. J., Zannis V. I. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. J Lipid Res: 2010; 51 6 1513 1523
    • (2010) J Lipid Res , vol.51 , Issue.6 , pp. 1513-1523
    • Iliopoulos, D.1    Drosatos, K.2    Hiyama, Y.3    Goldberg, I.J.4    Zannis, V.I.5
  • 22
    • 33645075443 scopus 로고    scopus 로고
    • MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
    • Esau C., Davis S., Murray S. F., et al. miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab: 2006; 3 2 87 98
    • (2006) Cell Metab , vol.3 , Issue.2 , pp. 87-98
    • Esau, C.1    Davis, S.2    Murray, S.F.3
  • 23
    • 84895514052 scopus 로고    scopus 로고
    • The effect of miRNA-122 in regulating fat deposition in a cell line model
    • Nie Y. Q., Cao J., Zhou Y. J., et al. The effect of miRNA-122 in regulating fat deposition in a cell line model. J Cell Biochem: 2014; 115 5 839 846
    • (2014) J Cell Biochem , vol.115 , Issue.5 , pp. 839-846
    • Nie, Y.Q.1    Cao, J.2    Zhou, Y.J.3
  • 24
    • 70349393847 scopus 로고    scopus 로고
    • Differential expression of microRNAs in mouse liver under aberrant energy metabolic status
    • Li S., Chen X., Zhang H., et al. Differential expression of microRNAs in mouse liver under aberrant energy metabolic status. J Lipid Res: 2009; 50 9 1756 1765
    • (2009) J Lipid Res , vol.50 , Issue.9 , pp. 1756-1765
    • Li, S.1    Chen, X.2    Zhang, H.3
  • 25
    • 61949190974 scopus 로고    scopus 로고
    • Profiling microRNA expression: A snapshot of nonalcoholic steatohepatitis and a recording of its pathogenesis
    • Alisi A., Masotti A., Nobili V. Profiling microRNA expression: a snapshot of nonalcoholic steatohepatitis and a recording of its pathogenesis. Hepatology: 2009; 49 2 706 707
    • (2009) Hepatology , vol.49 , Issue.2 , pp. 706-707
    • Alisi, A.1    Masotti, A.2    Nobili, V.3
  • 26
    • 84872376663 scopus 로고    scopus 로고
    • Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis
    • Trebicka J., Anadol E., Elfimova N., et al. Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis. J Hepatol: 2013; 58 2 234 239
    • (2013) J Hepatol , vol.58 , Issue.2 , pp. 234-239
    • Trebicka, J.1    Anadol, E.2    Elfimova, N.3
  • 27
    • 84872488869 scopus 로고    scopus 로고
    • Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration
    • 01
    • Dippold R. P., Vadigepalli R., Gonye G. E., Patra B., Hoek J. B. Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration. Alcohol Clin Exp Res: 2013; 37 01 E59 E69
    • (2013) Alcohol Clin Exp Res , vol.37 , pp. E59-E69
    • Dippold, R.P.1    Vadigepalli, R.2    Gonye, G.E.3    Patra, B.4    Hoek, J.B.5
  • 28
    • 84864773072 scopus 로고    scopus 로고
    • MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
    • Tsai W. C., Hsu S. D., Hsu C. S., et al. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest: 2012; 122 8 2884 2897
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2884-2897
    • Tsai, W.C.1    Hsu, S.D.2    Hsu, C.S.3
  • 29
    • 84864761391 scopus 로고    scopus 로고
    • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
    • Hsu S. H., Wang B., Kota J., et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest: 2012; 122 8 2871 2883
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2871-2883
    • Hsu, S.H.1    Wang, B.2    Kota, J.3
  • 30
    • 84897014065 scopus 로고    scopus 로고
    • MiR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes
    • Bhatia H., Verma G., Datta M. miR-107 orchestrates ER stress induction and lipid accumulation by post-transcriptional regulation of fatty acid synthase in hepatocytes. Biochim Biophys Acta: 2014; 1839 4 334 343
    • (2014) Biochim Biophys Acta , vol.1839 , Issue.4 , pp. 334-343
    • Bhatia, H.1    Verma, G.2    Datta, M.3
  • 31
    • 84905014931 scopus 로고    scopus 로고
    • A novel function of microRNA 130a-3p in hepatic insulin sensitivity and liver steatosis
    • Xiao F., Yu J., Liu B., et al. A novel function of microRNA 130a-3p in hepatic insulin sensitivity and liver steatosis. Diabetes: 2014; 63 8 2631 2642
    • (2014) Diabetes , vol.63 , Issue.8 , pp. 2631-2642
    • Xiao, F.1    Yu, J.2    Liu, B.3
  • 32
    • 33645068185 scopus 로고    scopus 로고
    • Liver X receptors in cardiovascular and metabolic disease
    • Geyeregger R., Zeyda M., Stulnig T. M. Liver X receptors in cardiovascular and metabolic disease. Cell Mol Life Sci: 2006; 63 5 524 539
    • (2006) Cell Mol Life Sci , vol.63 , Issue.5 , pp. 524-539
    • Geyeregger, R.1    Zeyda, M.2    Stulnig, T.M.3
  • 33
    • 53349153430 scopus 로고    scopus 로고
    • Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
    • Higuchi N., Kato M., Shundo Y., et al. Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res: 2008; 38 11 1122 1129
    • (2008) Hepatol Res , vol.38 , Issue.11 , pp. 1122-1129
    • Higuchi, N.1    Kato, M.2    Shundo, Y.3
  • 34
    • 84874715904 scopus 로고    scopus 로고
    • MicroRNA-613 represses lipogenesis in HepG2 cells by downregulating LXRα
    • Zhong D., Zhang Y., Zeng Y. J., et al. MicroRNA-613 represses lipogenesis in HepG2 cells by downregulating LXRα Lipids Health Dis: 2013; 12 32
    • (2013) Lipids Health Dis , vol.12 , pp. 32
    • Zhong, D.1    Zhang, Y.2    Zeng, Y.J.3
  • 35
    • 84876329845 scopus 로고    scopus 로고
    • MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes
    • Zhong D., Huang G., Zhang Y., et al. MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes. Cell Signal: 2013; 25 6 1429 1437
    • (2013) Cell Signal , vol.25 , Issue.6 , pp. 1429-1437
    • Zhong, D.1    Huang, G.2    Zhang, Y.3
  • 36
    • 84894613848 scopus 로고    scopus 로고
    • Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis
    • Adlakha Y. K., Khanna S., Singh R., Singh V. P., Agrawal A., Saini N. Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis. Cell Death Dis: 2013; 4 e780
    • (2013) Cell Death Dis , vol.4 , pp. e780
    • Adlakha, Y.K.1    Khanna, S.2    Singh, R.3    Singh, V.P.4    Agrawal, A.5    Saini, N.6
  • 37
    • 84882573604 scopus 로고    scopus 로고
    • MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice
    • Miller A. M., Gilchrist D. S., Nijjar J., et al. MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. PLoS ONE: 2013; 8 8 e72324
    • (2013) PLoS ONE , vol.8 , Issue.8 , pp. e72324
    • Miller, A.M.1    Gilchrist, D.S.2    Nijjar, J.3
  • 38
    • 84876335568 scopus 로고    scopus 로고
    • MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells
    • Shirasaki T., Honda M., Shimakami T., et al. MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells. J Virol: 2013; 87 9 5270 5286
    • (2013) J Virol , vol.87 , Issue.9 , pp. 5270-5286
    • Shirasaki, T.1    Honda, M.2    Shimakami, T.3
  • 39
    • 84867370115 scopus 로고    scopus 로고
    • PPARs in Liver Diseases and Cancer: Epigenetic Regulation by MicroRNAs
    • Peyrou M., Ramadori P., Bourgoin L., Foti M. PPARs in Liver Diseases and Cancer: Epigenetic Regulation by MicroRNAs. PPAR Res: 2012; 2012 757803
    • (2012) PPAR Res , vol.2012 , pp. 757803
    • Peyrou, M.1    Ramadori, P.2    Bourgoin, L.3    Foti, M.4
  • 40
    • 19444383246 scopus 로고    scopus 로고
    • PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes
    • Schadinger S. E., Bucher N. L., Schreiber B. M., Farmer S. R. PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes. Am J Physiol Endocrinol Metab: 2005; 288 6 E1195 E1205
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , Issue.6 , pp. E1195-E1205
    • Schadinger, S.E.1    Bucher, N.L.2    Schreiber, B.M.3    Farmer, S.R.4
  • 41
  • 42
    • 84866362817 scopus 로고    scopus 로고
    • Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity
    • Zhou B., Li C., Qi W., et al. Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity. Diabetologia: 2012; 55 7 2032 2043
    • (2012) Diabetologia , vol.55 , Issue.7 , pp. 2032-2043
    • Zhou, B.1    Li, C.2    Qi, W.3
  • 43
    • 77951210885 scopus 로고    scopus 로고
    • A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition
    • Lee J., Padhye A., Sharma A., et al. A pathway involving farnesoid X receptor and small heterodimer partner positively regulates hepatic sirtuin 1 levels via microRNA-34a inhibition. J Biol Chem: 2010; 285 17 12604 12611
    • (2010) J Biol Chem , vol.285 , Issue.17 , pp. 12604-12611
    • Lee, J.1    Padhye, A.2    Sharma, A.3
  • 44
    • 84858968923 scopus 로고    scopus 로고
    • MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1
    • Yin H., Hu M., Zhang R., Shen Z., Flatow L., You M. MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1. J Biol Chem: 2012; 287 13 9817 9826
    • (2012) J Biol Chem , vol.287 , Issue.13 , pp. 9817-9826
    • Yin, H.1    Hu, M.2    Zhang, R.3    Shen, Z.4    Flatow, L.5    You, M.6
  • 45
    • 79959326172 scopus 로고    scopus 로고
    • MiR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
    • Dávalos A., Goedeke L., Smibert P., et al. miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling. Proc Natl Acad Sci U S A: 2011; 108 22 9232 9237
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.22 , pp. 9232-9237
    • Dávalos, A.1    Goedeke, L.2    Smibert, P.3
  • 46
    • 84876194497 scopus 로고    scopus 로고
    • Upregulation of miR-15b in NAFLD models and in the serum of patients with fatty liver disease
    • Zhang Y., Cheng X., Lu Z., et al. Upregulation of miR-15b in NAFLD models and in the serum of patients with fatty liver disease. Diabetes Res Clin Pract: 2013; 99 3 327 334
    • (2013) Diabetes Res Clin Pract , vol.99 , Issue.3 , pp. 327-334
    • Zhang, Y.1    Cheng, X.2    Lu, Z.3
  • 47
    • 84898439031 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Molecular mechanisms for the hepatic steatosis
    • Koo S. H. Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis. Clin Mol Hepatol: 2013; 19 3 210 215
    • (2013) Clin Mol Hepatol , vol.19 , Issue.3 , pp. 210-215
    • Koo, S.H.1
  • 48
    • 80054900644 scopus 로고    scopus 로고
    • MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1
    • Ramirez C. M., Dávalos A., Goedeke L., et al. MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1. Arterioscler Thromb Vasc Biol: 2011; 31 11 2707 2714
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.11 , pp. 2707-2714
    • Ramirez, C.M.1    Dávalos, A.2    Goedeke, L.3
  • 49
    • 77958553499 scopus 로고    scopus 로고
    • Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation
    • Gerin I., Clerbaux L. A., Haumont O., et al. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem: 2010; 285 44 33652 33661
    • (2010) J Biol Chem , vol.285 , Issue.44 , pp. 33652-33661
    • Gerin, I.1    Clerbaux, L.A.2    Haumont, O.3
  • 50
    • 84878958446 scopus 로고    scopus 로고
    • A regulatory role for microRNA 33∗ in controlling lipid metabolism gene expression
    • Goedeke L., Vales-Lara F. M., Fenstermaker M., et al. A regulatory role for microRNA 33∗ in controlling lipid metabolism gene expression. Mol Cell Biol: 2013; 33 11 2339 2352
    • (2013) Mol Cell Biol , vol.33 , Issue.11 , pp. 2339-2352
    • Goedeke, L.1    Vales-Lara, F.M.2    Fenstermaker, M.3
  • 51
    • 84865794377 scopus 로고    scopus 로고
    • MiR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity
    • Allen R. M., Marquart T. J., Albert C. J., et al. miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity. EMBO Mol Med: 2012; 4 9 882 895
    • (2012) EMBO Mol Med , vol.4 , Issue.9 , pp. 882-895
    • Allen, R.M.1    Marquart, T.J.2    Albert, C.J.3
  • 52
    • 84860887952 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice
    • Hoekstra M., van der Sluis R. J., Kuiper J., Van Berkel T. J. Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice. J Nutr Biochem: 2012; 23 6 622 628
    • (2012) J Nutr Biochem , vol.23 , Issue.6 , pp. 622-628
    • Hoekstra, M.1    Van Der Sluis, R.J.2    Kuiper, J.3    Van Berkel, T.J.4
  • 53
    • 84888205573 scopus 로고    scopus 로고
    • Regulation of ABCA1 protein expression and function in hepatic and pancreatic islet cells by miR-145
    • Kang M. H., Zhang L. H., Wijesekara N., et al. Regulation of ABCA1 protein expression and function in hepatic and pancreatic islet cells by miR-145. Arterioscler Thromb Vasc Biol: 2013; 33 12 2724 2732
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.12 , pp. 2724-2732
    • Kang, M.H.1    Zhang, L.H.2    Wijesekara, N.3
  • 54
    • 84928573822 scopus 로고    scopus 로고
    • Transcription factor networks regulating hepatic fatty acid metabolism
    • (May)
    • Karagianni P., Talianidis I. Transcription factor networks regulating hepatic fatty acid metabolism. Biochim Biophys Acta: 2014;; (May): 9
    • (2014) Biochim Biophys Acta , pp. 9
    • Karagianni, P.1    Talianidis, I.2
  • 55
    • 84894864720 scopus 로고    scopus 로고
    • Hepatitis C virus induced up-regulation of microRNA-27: A novel mechanism for hepatic steatosis
    • Singaravelu R., Chen R., Lyn R. K., et al. Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis. Hepatology: 2014; 59 1 98 108
    • (2014) Hepatology , vol.59 , Issue.1 , pp. 98-108
    • Singaravelu, R.1    Chen, R.2    Lyn, R.K.3
  • 56
    • 80054764011 scopus 로고    scopus 로고
    • PPARα is regulated by miR-21 and miR-27b in human liver
    • Kida K., Nakajima M., Mohri T., et al. PPARα is regulated by miR-21 and miR-27b in human liver. Pharm Res: 2011; 28 10 2467 2476
    • (2011) Pharm Res , vol.28 , Issue.10 , pp. 2467-2476
    • Kida, K.1    Nakajima, M.2    Mohri, T.3
  • 57
    • 65449119905 scopus 로고    scopus 로고
    • Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes
    • Vinciguerra M., Sgroi A., Veyrat-Durebex C., Rubbia-Brandt L., Buhler L. H., Foti M. Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes. Hepatology: 2009; 49 4 1176 1184
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1176-1184
    • Vinciguerra, M.1    Sgroi, A.2    Veyrat-Durebex, C.3    Rubbia-Brandt, L.4    Buhler, L.H.5    Foti, M.6
  • 58
    • 73449136157 scopus 로고    scopus 로고
    • Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD
    • Zheng L., Lv G. C., Sheng J., Yang Y. D. Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD. J Gastroenterol Hepatol: 2010; 25 1 156 163
    • (2010) J Gastroenterol Hepatol , vol.25 , Issue.1 , pp. 156-163
    • Zheng, L.1    Lv, G.C.2    Sheng, J.3    Yang, Y.D.4
  • 59
    • 34547126004 scopus 로고    scopus 로고
    • MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines
    • Baroukh N., Ravier M. A., Loder M. K., et al. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem: 2007; 282 27 19575 19588
    • (2007) J Biol Chem , vol.282 , Issue.27 , pp. 19575-19588
    • Baroukh, N.1    Ravier, M.A.2    Loder, M.K.3
  • 60
    • 84867931323 scopus 로고    scopus 로고
    • Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet
    • Ahn J., Lee H., Jung C. H., Ha T. Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. Mol Nutr Food Res: 2012; 56 11 1665 1674
    • (2012) Mol Nutr Food Res , vol.56 , Issue.11 , pp. 1665-1674
    • Ahn, J.1    Lee, H.2    Jung, C.H.3    Ha, T.4
  • 61
    • 37349083834 scopus 로고    scopus 로고
    • PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism
    • Vinciguerra M., Veyrat-Durebex C., Moukil M. A., Rubbia-Brandt L., Rohner-Jeanrenaud F., Foti M. PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism. Gastroenterology: 2008; 134 1 268 280
    • (2008) Gastroenterology , vol.134 , Issue.1 , pp. 268-280
    • Vinciguerra, M.1    Veyrat-Durebex, C.2    Moukil, M.A.3    Rubbia-Brandt, L.4    Rohner-Jeanrenaud, F.5    Foti, M.6
  • 63
    • 2142762456 scopus 로고    scopus 로고
    • Fatty liver in familial hypobetalipoproteinemia: Roles of the APOB defects, intra-abdominal adipose tissue, and insulin sensitivity
    • Tanoli T., Yue P., Yablonskiy D., Schonfeld G. Fatty liver in familial hypobetalipoproteinemia: roles of the APOB defects, intra-abdominal adipose tissue, and insulin sensitivity. J Lipid Res: 2004; 45 5 941 947
    • (2004) J Lipid Res , vol.45 , Issue.5 , pp. 941-947
    • Tanoli, T.1    Yue, P.2    Yablonskiy, D.3    Schonfeld, G.4
  • 64
    • 84880288761 scopus 로고    scopus 로고
    • MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion
    • Soh J., Iqbal J., Queiroz J., Fernandez-Hernando C., Hussain M. M. MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion. Nat Med: 2013; 19 7 892 900
    • (2013) Nat Med , vol.19 , Issue.7 , pp. 892-900
    • Soh, J.1    Iqbal, J.2    Queiroz, J.3    Fernandez-Hernando, C.4    Hussain, M.M.5
  • 65
    • 84901062946 scopus 로고    scopus 로고
    • Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
    • González-Rodríguez A., Mayoral R., Agra N., et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis: 2014; 5 e1179
    • (2014) Cell Death Dis , vol.5 , pp. e1179
    • González-Rodríguez, A.1    Mayoral, R.2    Agra, N.3
  • 66
    • 84876287362 scopus 로고    scopus 로고
    • Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice
    • Lin C. W., Zhang H., Li M., et al. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J Hepatol: 2013; 58 5 993 999
    • (2013) J Hepatol , vol.58 , Issue.5 , pp. 993-999
    • Lin, C.W.1    Zhang, H.2    Li, M.3
  • 67
    • 84857582672 scopus 로고    scopus 로고
    • Autophagy protects cells from HCV-induced defects in lipid metabolism
    • Vescovo T., Romagnoli A., Perdomo A. B., et al. Autophagy protects cells from HCV-induced defects in lipid metabolism. Gastroenterology: 2012; 142 3 644 653.e3
    • (2012) Gastroenterology , vol.142 , Issue.3 , pp. 644-653e3
    • Vescovo, T.1    Romagnoli, A.2    Perdomo, A.B.3
  • 68
    • 84868627011 scopus 로고    scopus 로고
    • MicroRNA regulation of autophagy
    • Frankel L. B., Lund A. H. MicroRNA regulation of autophagy. Carcinogenesis: 2012; 33 11 2018 2025
    • (2012) Carcinogenesis , vol.33 , Issue.11 , pp. 2018-2025
    • Frankel, L.B.1    Lund, A.H.2
  • 70
    • 84887296519 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting Rheb
    • Wang J., Yang K., Zhou L., et al. MicroRNA-155 promotes autophagy to eliminate intracellular mycobacteria by targeting Rheb. PLoS Pathog: 2013; 9 10 e1003697
    • (2013) PLoS Pathog , vol.9 , Issue.10 , pp. e1003697
    • Wang, J.1    Yang, K.2    Zhou, L.3
  • 71
    • 84876211114 scopus 로고    scopus 로고
    • MiR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
    • Xu Y., An Y., Wang Y., et al. miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep: 2013; 29 5 2019 2024
    • (2013) Oncol Rep , vol.29 , Issue.5 , pp. 2019-2024
    • Xu, Y.1    An, Y.2    Wang, Y.3
  • 72
    • 84865249866 scopus 로고    scopus 로고
    • Epigenetic regulation of miR-34a expression in alcoholic liver injury
    • Meng F., Glaser S. S., Francis H., et al. Epigenetic regulation of miR-34a expression in alcoholic liver injury. Am J Pathol: 2012; 181 3 804 817
    • (2012) Am J Pathol , vol.181 , Issue.3 , pp. 804-817
    • Meng, F.1    Glaser, S.S.2    Francis, H.3
  • 73
    • 84872616169 scopus 로고    scopus 로고
    • MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9
    • Yang J., Chen D., He Y., et al. MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9. Age (Dordr): 2013; 35 1 11 22
    • (2013) Age (Dordr) , vol.35 , Issue.1 , pp. 11-22
    • Yang, J.1    Chen, D.2    He, Y.3
  • 74
    • 84867099976 scopus 로고    scopus 로고
    • Expanding roles for SREBP in metabolism
    • Shao W., Espenshade P. J. Expanding roles for SREBP in metabolism. Cell Metab: 2012; 16 4 414 419
    • (2012) Cell Metab , vol.16 , Issue.4 , pp. 414-419
    • Shao, W.1    Espenshade, P.J.2
  • 75
    • 79953756678 scopus 로고    scopus 로고
    • Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy
    • Seo Y. K., Jeon T. I., Chong H. K., Biesinger J., Xie X., Osborne T. F. Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy. Cell Metab: 2011; 13 4 367 375
    • (2011) Cell Metab , vol.13 , Issue.4 , pp. 367-375
    • Seo, Y.K.1    Jeon, T.I.2    Chong, H.K.3    Biesinger, J.4    Xie, X.5    Osborne, T.F.6
  • 76
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: Common threads and missing links
    • Samuel V. T., Shulman G. I. Mechanisms for insulin resistance: common threads and missing links. Cell: 2012; 148 5 852 871
    • (2012) Cell , vol.148 , Issue.5 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 77
    • 79959845414 scopus 로고    scopus 로고
    • MicroRNAs 103 and 107 regulate insulin sensitivity
    • Trajkovski M., Hausser J., Soutschek J., et al. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature: 2011; 474 7353 649 653
    • (2011) Nature , vol.474 , Issue.7353 , pp. 649-653
    • Trajkovski, M.1    Hausser, J.2    Soutschek, J.3
  • 79
    • 84899490560 scopus 로고    scopus 로고
    • MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling
    • Wang Y., Hu C., Cheng J., et al. MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling. Biochem Biophys Res Commun: 2014; 446 4 1255 1260
    • (2014) Biochem Biophys Res Commun , vol.446 , Issue.4 , pp. 1255-1260
    • Wang, Y.1    Hu, C.2    Cheng, J.3
  • 80
    • 84896066257 scopus 로고    scopus 로고
    • MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells
    • Wen F., Yang Y., Jin D., Sun J., Yu X., Yang Z. MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells. Biochem Biophys Res Commun: 2014; 445 2 517 523
    • (2014) Biochem Biophys Res Commun , vol.445 , Issue.2 , pp. 517-523
    • Wen, F.1    Yang, Y.2    Jin, D.3    Sun, J.4    Yu, X.5    Yang, Z.6
  • 81
    • 79953048345 scopus 로고    scopus 로고
    • The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes
    • Ryu H. S., Park S. Y., Ma D., Zhang J., Lee W. The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes. PLoS ONE: 2011; 6 3 e17343
    • (2011) PLoS ONE , vol.6 , Issue.3 , pp. e17343
    • Ryu, H.S.1    Park, S.Y.2    Ma, D.3    Zhang, J.4    Lee, W.5
  • 82
    • 78650523982 scopus 로고    scopus 로고
    • MiR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells
    • Pandey A. K., Verma G., Vig S., Srivastava S., Srivastava A. K., Datta M. miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells. Mol Cell Endocrinol: 2011; 332 1-2 125 133
    • (2011) Mol Cell Endocrinol , vol.332 , Issue.12 , pp. 125-133
    • Pandey, A.K.1    Verma, G.2    Vig, S.3    Srivastava, S.4    Srivastava, A.K.5    Datta, M.6
  • 83
    • 79952450963 scopus 로고    scopus 로고
    • Non-genomic loss of PTEN function in cancer: Not in my genes
    • Leslie N. R., Foti M. Non-genomic loss of PTEN function in cancer: not in my genes. Trends Pharmacol Sci: 2011; 32 3 131 140
    • (2011) Trends Pharmacol Sci , vol.32 , Issue.3 , pp. 131-140
    • Leslie, N.R.1    Foti, M.2
  • 84
    • 79953317808 scopus 로고    scopus 로고
    • Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
    • Jordan S. D., Krüger M., Willmes D. M., et al. Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nat Cell Biol: 2011; 13 4 434 446
    • (2011) Nat Cell Biol , vol.13 , Issue.4 , pp. 434-446
    • Jordan, S.D.1    Krüger, M.2    Willmes, D.M.3
  • 85
    • 84884307308 scopus 로고    scopus 로고
    • Oxysterol-binding proteins: Functions in cell regulation beyond lipid metabolism
    • Weber-Boyvat M., Zhong W., Yan D., Olkkonen V. M. Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism. Biochem Pharmacol: 2013; 86 1 89 95
    • (2013) Biochem Pharmacol , vol.86 , Issue.1 , pp. 89-95
    • Weber-Boyvat, M.1    Zhong, W.2    Yan, D.3    Olkkonen, V.M.4
  • 86
    • 84883496441 scopus 로고    scopus 로고
    • Circulating inflamma-miRs in aging and age-related diseases
    • Olivieri F., Rippo M. R., Procopio A. D., Fazioli F. Circulating inflamma-miRs in aging and age-related diseases. Front Genet: 2013; 4 121
    • (2013) Front Genet , vol.4 , pp. 121
    • Olivieri, F.1    Rippo, M.R.2    Procopio, A.D.3    Fazioli, F.4
  • 87
    • 84893692701 scopus 로고    scopus 로고
    • The functional role of microRNAs in alcoholic liver injury
    • McDaniel K., Herrera L., Zhou T., et al. The functional role of microRNAs in alcoholic liver injury. J Cell Mol Med: 2014; 18 2 197 207
    • (2014) J Cell Mol Med , vol.18 , Issue.2 , pp. 197-207
    • McDaniel, K.1    Herrera, L.2    Zhou, T.3
  • 88
    • 78651399501 scopus 로고    scopus 로고
    • Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor alpha (TNFalpha) production via increased mRNA half-life in alcoholic liver disease
    • Bala S., Marcos M., Kodys K., et al. Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor alpha (TNFalpha) production via increased mRNA half-life in alcoholic liver disease. J Biol Chem: 2011; 286 2 1436 1444
    • (2011) J Biol Chem , vol.286 , Issue.2 , pp. 1436-1444
    • Bala, S.1    Marcos, M.2    Kodys, K.3
  • 89
    • 84891828421 scopus 로고    scopus 로고
    • MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver
    • Jiang M., Broering R., Trippler M., et al. MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver. J Viral Hepat: 2014; 21 2 99 110
    • (2014) J Viral Hepat , vol.21 , Issue.2 , pp. 99-110
    • Jiang, M.1    Broering, R.2    Trippler, M.3
  • 90
    • 70349308694 scopus 로고    scopus 로고
    • MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice
    • Dolganiuc A., Petrasek J., Kodys K., et al. MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. Alcohol Clin Exp Res: 2009; 33 10 1704 1710
    • (2009) Alcohol Clin Exp Res , vol.33 , Issue.10 , pp. 1704-1710
    • Dolganiuc, A.1    Petrasek, J.2    Kodys, K.3
  • 91
    • 84895492066 scopus 로고    scopus 로고
    • Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis
    • Sarma N. J., Tiriveedhi V., Crippin J. S., Chapman W. C., Mohanakumar T. Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis. J Virol: 2014; 88 7 3733 3743
    • (2014) J Virol , vol.88 , Issue.7 , pp. 3733-3743
    • Sarma, N.J.1    Tiriveedhi, V.2    Crippin, J.S.3    Chapman, W.C.4    Mohanakumar, T.5
  • 92
    • 58149386462 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression
    • Cheung O., Puri P., Eicken C., et al. Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology: 2008; 48 6 1810 1820
    • (2008) Hepatology , vol.48 , Issue.6 , pp. 1810-1820
    • Cheung, O.1    Puri, P.2    Eicken, C.3
  • 93
    • 84864770242 scopus 로고    scopus 로고
    • MiR-122 regulates hepatic lipid metabolism and tumor suppression
    • Wen J., Friedman J. R. miR-122 regulates hepatic lipid metabolism and tumor suppression. J Clin Invest: 2012; 122 8 2773 2776
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2773-2776
    • Wen, J.1    Friedman, J.R.2
  • 94
    • 79960685445 scopus 로고    scopus 로고
    • A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA
    • Cazanave S. C., Mott J. L., Elmi N. A., et al. A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA. J Lipid Res: 2011; 52 8 1517 1525
    • (2011) J Lipid Res , vol.52 , Issue.8 , pp. 1517-1525
    • Cazanave, S.C.1    Mott, J.L.2    Elmi, N.A.3
  • 95
    • 84859445823 scopus 로고    scopus 로고
    • TGF-β in progression of liver disease
    • Dooley S., ten Dijke P. TGF-β in progression of liver disease. Cell Tissue Res: 2012; 347 1 245 256
    • (2012) Cell Tissue Res , vol.347 , Issue.1 , pp. 245-256
    • Dooley, S.1    Ten Dijke, P.2
  • 96
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • Friedman S. L. Mechanisms of hepatic fibrogenesis. Gastroenterology: 2008; 134 6 1655 1669
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 97
    • 46049097550 scopus 로고    scopus 로고
    • The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease
    • Miele L., Beale G., Patman G., et al. The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease. Gastroenterology: 2008; 135 1 282 291.e1
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 282-291e1
    • Miele, L.1    Beale, G.2    Patman, G.3
  • 98
    • 84905904910 scopus 로고    scopus 로고
    • MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway
    • Tu X., Zhang H., Zhang J., et al. MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway. J Pathol: 2014; 234 1 46 59
    • (2014) J Pathol , vol.234 , Issue.1 , pp. 46-59
    • Tu, X.1    Zhang, H.2    Zhang, J.3
  • 99
    • 84863532308 scopus 로고    scopus 로고
    • Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis
    • Lakner A. M., Steuerwald N. M., Walling T. L., et al. Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis. Hepatology: 2012; 56 1 300 310
    • (2012) Hepatology , vol.56 , Issue.1 , pp. 300-310
    • Lakner, A.M.1    Steuerwald, N.M.2    Walling, T.L.3
  • 100
    • 69449087939 scopus 로고    scopus 로고
    • Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways
    • Guo C. J., Pan Q., Cheng T., Jiang B., Chen G. Y., Li D. G. Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways. FEBS J: 2009; 276 18 5163 5176
    • (2009) FEBS J , vol.276 , Issue.18 , pp. 5163-5176
    • Guo, C.J.1    Pan, Q.2    Cheng, T.3    Jiang, B.4    Chen, G.Y.5    Li, D.G.6
  • 101
    • 84864011802 scopus 로고    scopus 로고
    • MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4
    • He Y., Huang C., Sun X., Long X. R., Lv X. W., Li J. MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4. Cell Signal: 2012; 24 10 1923 1930
    • (2012) Cell Signal , vol.24 , Issue.10 , pp. 1923-1930
    • He, Y.1    Huang, C.2    Sun, X.3    Long, X.R.4    Lv, X.W.5    Li, J.6
  • 102
    • 79959509832 scopus 로고    scopus 로고
    • MiRNA studies in in vitro and in vivo activated hepatic stellate cells
    • Maubach G., Lim M. C., Chen J., Yang H., Zhuo L. miRNA studies in in vitro and in vivo activated hepatic stellate cells. World J Gastroenterol: 2011; 17 22 2748 2773
    • (2011) World J Gastroenterol , vol.17 , Issue.22 , pp. 2748-2773
    • Maubach, G.1    Lim, M.C.2    Chen, J.3    Yang, H.4    Zhuo, L.5
  • 103
    • 78649674133 scopus 로고    scopus 로고
    • Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans
    • Marquez R. T., Bandyopadhyay S., Wendlandt E. B., et al. Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans. Lab Invest: 2010; 90 12 1727 1736
    • (2010) Lab Invest , vol.90 , Issue.12 , pp. 1727-1736
    • Marquez, R.T.1    Bandyopadhyay, S.2    Wendlandt, E.B.3
  • 104
    • 84891387376 scopus 로고    scopus 로고
    • The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development
    • Zhang Z., Zha Y., Hu W., et al. The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development. J Biol Chem: 2013; 288 52 37082 37093
    • (2013) J Biol Chem , vol.288 , Issue.52 , pp. 37082-37093
    • Zhang, Z.1    Zha, Y.2    Hu, W.3
  • 105
    • 84855591712 scopus 로고    scopus 로고
    • TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells
    • Wang T., Zhang L., Shi C., et al. TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells. Int J Biochem Cell Biol: 2012; 44 2 366 376
    • (2012) Int J Biochem Cell Biol , vol.44 , Issue.2 , pp. 366-376
    • Wang, T.1    Zhang, L.2    Shi, C.3
  • 106
    • 84864541155 scopus 로고    scopus 로고
    • TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion
    • Dey N., Ghosh-Choudhury N., Kasinath B. S., Choudhury G. G. TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion. PLoS ONE: 2012; 7 8 e42316
    • (2012) PLoS ONE , vol.7 , Issue.8 , pp. e42316
    • Dey, N.1    Ghosh-Choudhury, N.2    Kasinath, B.S.3    Choudhury, G.G.4
  • 107
    • 84887187262 scopus 로고    scopus 로고
    • Profibrotic effect of miR-33a with Akt activation in hepatic stellate cells
    • Li Z. J., Ou-Yang P. H., Han X. P. Profibrotic effect of miR-33a with Akt activation in hepatic stellate cells. Cell Signal: 2014; 26 1 141 148
    • (2014) Cell Signal , vol.26 , Issue.1 , pp. 141-148
    • Li, Z.J.1    Ou-Yang, P.H.2    Han, X.P.3
  • 108
    • 84868584039 scopus 로고    scopus 로고
    • Induction of microRNA-214-5p in human and rodent liver fibrosis
    • Iizuka M., Ogawa T., Enomoto M., et al. Induction of microRNA-214-5p in human and rodent liver fibrosis. Fibrogenesis Tissue Repair: 2012; 5 1 12
    • (2012) Fibrogenesis Tissue Repair , vol.5 , Issue.1 , pp. 12
    • Iizuka, M.1    Ogawa, T.2    Enomoto, M.3
  • 109
    • 84860329438 scopus 로고    scopus 로고
    • MiR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients
    • Wang B., Li W., Guo K., Xiao Y., Wang Y., Fan J. miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. Biochem Biophys Res Commun: 2012; 421 1 4 8
    • (2012) Biochem Biophys Res Commun , vol.421 , Issue.1 , pp. 4-8
    • Wang, B.1    Li, W.2    Guo, K.3    Xiao, Y.4    Wang, Y.5    Fan, J.6
  • 110
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F., Henson R., Wehbe-Janek H., Ghoshal K., Jacob S. T., Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology: 2007; 133 2 647 658
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 112
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T., Gross C., Fiedler J., et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature: 2008; 456 7224 980 984
    • (2008) Nature , vol.456 , Issue.7224 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 113
    • 59849084351 scopus 로고    scopus 로고
    • Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
    • Ji J., Zhang J., Huang G., Qian J., Wang X., Mei S. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett: 2009; 583 4 759 766
    • (2009) FEBS Lett , vol.583 , Issue.4 , pp. 759-766
    • Ji, J.1    Zhang, J.2    Huang, G.3    Qian, J.4    Wang, X.5    Mei, S.6
  • 114
    • 73549111067 scopus 로고    scopus 로고
    • Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation
    • Venugopal S. K., Jiang J., Kim T. H., et al. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am J Physiol Gastrointest Liver Physiol: 2010; 298 1 G101 G106
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298 , Issue.1 , pp. G101-G106
    • Venugopal, S.K.1    Jiang, J.2    Kim, T.H.3
  • 115
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • 714.e1-714.e4
    • Mann J., Chu D. C., Maxwell A., et al. MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology: 2010; 138 2 705 714, 714.e1-714.e4
    • (2010) Gastroenterology , vol.138 , Issue.2 , pp. 705-714
    • Mann, J.1    Chu, D.C.2    Maxwell, A.3
  • 116
    • 79958845153 scopus 로고    scopus 로고
    • Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation
    • Chen C., Wu C. Q., Zhang Z. Q., Yao D. K., Zhu L. Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation. Exp Cell Res: 2011; 317 12 1714 1725
    • (2011) Exp Cell Res , vol.317 , Issue.12 , pp. 1714-1725
    • Chen, C.1    Wu, C.Q.2    Zhang, Z.Q.3    Yao, D.K.4    Zhu, L.5
  • 117
    • 70349783724 scopus 로고    scopus 로고
    • Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells
    • Guo C. J., Pan Q., Jiang B., Chen G. Y., Li D. G. Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells. Apoptosis: 2009; 14 11 1331 1340
    • (2009) Apoptosis , vol.14 , Issue.11 , pp. 1331-1340
    • Guo, C.J.1    Pan, Q.2    Jiang, B.3    Chen, G.Y.4    Li, D.G.5
  • 118
    • 79551541594 scopus 로고    scopus 로고
    • The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families
    • Murakami Y., Toyoda H., Tanaka M., et al. The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. PLoS ONE: 2011; 6 1 e16081
    • (2011) PLoS ONE , vol.6 , Issue.1 , pp. e16081
    • Murakami, Y.1    Toyoda, H.2    Tanaka, M.3
  • 119
    • 84857866299 scopus 로고    scopus 로고
    • Micro-RNA profiling in human serum reveals compartment-specific roles of miR-571 and miR-652 in liver cirrhosis
    • Roderburg C., Mollnow T., Bongaerts B., et al. Micro-RNA profiling in human serum reveals compartment-specific roles of miR-571 and miR-652 in liver cirrhosis. PLoS ONE: 2012; 7 3 e32999
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. e32999
    • Roderburg, C.1    Mollnow, T.2    Bongaerts, B.3
  • 120
    • 77957259450 scopus 로고    scopus 로고
    • Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice
    • Pogribny I. P., Starlard-Davenport A., Tryndyak V. P., et al. Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. Lab Invest: 2010; 90 10 1437 1446
    • (2010) Lab Invest , vol.90 , Issue.10 , pp. 1437-1446
    • Pogribny, I.P.1    Starlard-Davenport, A.2    Tryndyak, V.P.3
  • 121
    • 84874109529 scopus 로고    scopus 로고
    • MiR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression
    • Li J., Ghazwani M., Zhang Y., et al. miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression. J Hepatol: 2013; 58 3 522 528
    • (2013) J Hepatol , vol.58 , Issue.3 , pp. 522-528
    • Li, J.1    Ghazwani, M.2    Zhang, Y.3
  • 122
    • 84861197159 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace
    • Baffy G., Brunt E. M., Caldwell S. H. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. J Hepatol: 2012; 56 6 1384 1391
    • (2012) J Hepatol , vol.56 , Issue.6 , pp. 1384-1391
    • Baffy, G.1    Brunt, E.M.2    Caldwell, S.H.3
  • 124
    • 84877263372 scopus 로고    scopus 로고
    • Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance
    • Karakatsanis A., Papaconstantinou I., Gazouli M., Lyberopoulou A., Polymeneas G., Voros D. Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance. Mol Carcinog: 2013; 52 4 297 303
    • (2013) Mol Carcinog , vol.52 , Issue.4 , pp. 297-303
    • Karakatsanis, A.1    Papaconstantinou, I.2    Gazouli, M.3    Lyberopoulou, A.4    Polymeneas, G.5    Voros, D.6
  • 125
    • 84857953621 scopus 로고    scopus 로고
    • Mir-33 regulates cell proliferation and cell cycle progression
    • Cirera-Salinas D., Pauta M., Allen R. M., et al. Mir-33 regulates cell proliferation and cell cycle progression. Cell Cycle: 2012; 11 5 922 933
    • (2012) Cell Cycle , vol.11 , Issue.5 , pp. 922-933
    • Cirera-Salinas, D.1    Pauta, M.2    Allen, R.M.3
  • 126
    • 70349976819 scopus 로고    scopus 로고
    • Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
    • Coulouarn C., Factor V. M., Andersen J. B., Durkin M. E., Thorgeirsson S. S. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene: 2009; 28 40 3526 3536
    • (2009) Oncogene , vol.28 , Issue.40 , pp. 3526-3536
    • Coulouarn, C.1    Factor, V.M.2    Andersen, J.B.3    Durkin, M.E.4    Thorgeirsson, S.S.5
  • 127
    • 79957791258 scopus 로고    scopus 로고
    • Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases
    • Fujiyoshi M., Ozaki M. Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases. J Hepatobiliary Pancreat Sci: 2011; 18 1 13 22
    • (2011) J Hepatobiliary Pancreat Sci , vol.18 , Issue.1 , pp. 13-22
    • Fujiyoshi, M.1    Ozaki, M.2
  • 128
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker S., Marais R., Zhu A. X. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene: 2010; 29 36 4989 5005
    • (2010) Oncogene , vol.29 , Issue.36 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 129
    • 84856695673 scopus 로고    scopus 로고
    • Circulating microRNAs: Novel biomarkers and extracellular communicators in cardiovascular disease
    • Creemers E. E., Tijsen A. J., Pinto Y. M. Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res: 2012; 110 3 483 495
    • (2012) Circ Res , vol.110 , Issue.3 , pp. 483-495
    • Creemers, E.E.1    Tijsen, A.J.2    Pinto, Y.M.3
  • 130
    • 33747616431 scopus 로고    scopus 로고
    • Membrane-derived microvesicles: Important and underappreciated mediators of cell-to-cell communication
    • Ratajczak J., Wysoczynski M., Hayek F., Janowska-Wieczorek A., Ratajczak M. Z. Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication. Leukemia: 2006; 20 9 1487 1495
    • (2006) Leukemia , vol.20 , Issue.9 , pp. 1487-1495
    • Ratajczak, J.1    Wysoczynski, M.2    Hayek, F.3    Janowska-Wieczorek, A.4    Ratajczak, M.Z.5
  • 131
    • 84879448114 scopus 로고    scopus 로고
    • Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver
    • Yamada H., Suzuki K., Ichino N., et al. Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver. Clin Chim Acta: 2013; 424 99 103
    • (2013) Clin Chim Acta , vol.424 , pp. 99-103
    • Yamada, H.1    Suzuki, K.2    Ichino, N.3
  • 132
    • 84898605517 scopus 로고    scopus 로고
    • Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C
    • Zhang X., Zhang Z., Dai F., et al. Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C. PLoS ONE: 2014; 9 3 e92112
    • (2014) PLoS ONE , vol.9 , Issue.3 , pp. e92112
    • Zhang, X.1    Zhang, Z.2    Dai, F.3
  • 133
    • 63149121152 scopus 로고    scopus 로고
    • Circulating microRNAs, potential biomarkers for drug-induced liver injury
    • Wang K., Zhang S., Marzolf B., et al. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A: 2009; 106 11 4402 4407
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.11 , pp. 4402-4407
    • Wang, K.1    Zhang, S.2    Marzolf, B.3
  • 134
    • 84904470997 scopus 로고    scopus 로고
    • Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease
    • Miyaaki H., Ichikawa T., Kamo Y., et al. Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease. Liver Int: 2014; 34 7 e302 e307
    • (2014) Liver Int , vol.34 , Issue.7 , pp. e302-e307
    • Miyaaki, H.1    Ichikawa, T.2    Kamo, Y.3
  • 135
    • 84861728344 scopus 로고    scopus 로고
    • Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet
    • Tryndyak V. P., Latendresse J. R., Montgomery B., et al. Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet. Toxicol Appl Pharmacol: 2012; 262 1 52 59
    • (2012) Toxicol Appl Pharmacol , vol.262 , Issue.1 , pp. 52-59
    • Tryndyak, V.P.1    Latendresse, J.R.2    Montgomery, B.3
  • 136
    • 84904066495 scopus 로고    scopus 로고
    • Micro-RNA-122 levels in acute liver failure and chronic hepatitis C
    • Acute Liver Failure Study Group.
    • Dubin P. H., Yuan H., Devine R. K., Hynan L. S., Jain M. K., Lee W. M.; Acute Liver Failure Study Group. Micro-RNA-122 levels in acute liver failure and chronic hepatitis C. J Med Virol: 2014; 86 9 1507 1514
    • (2014) J Med Virol , vol.86 , Issue.9 , pp. 1507-1514
    • Dubin, P.H.1    Yuan, H.2    Devine, R.K.3    Hynan, L.S.4    Jain, M.K.5    Lee, W.M.6
  • 137
    • 80052008851 scopus 로고    scopus 로고
    • Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease
    • Cermelli S., Ruggieri A., Marrero J. A., Ioannou G. N., Beretta L. Circulating microRNAs in patients with chronic hepatitis C and non-alcoholic fatty liver disease. PLoS ONE: 2011; 6 8 e23937
    • (2011) PLoS ONE , vol.6 , Issue.8 , pp. e23937
    • Cermelli, S.1    Ruggieri, A.2    Marrero, J.A.3    Ioannou, G.N.4    Beretta, L.5
  • 138
    • 84881554943 scopus 로고    scopus 로고
    • Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis
    • Chen Y. P., Jin X., Xiang Z., Chen S. H., Li Y. M. Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis. Liver Int: 2013; 33 8 1257 1265
    • (2013) Liver Int , vol.33 , Issue.8 , pp. 1257-1265
    • Chen, Y.P.1    Jin, X.2    Xiang, Z.3    Chen, S.H.4    Li, Y.M.5
  • 139
    • 84868211262 scopus 로고    scopus 로고
    • Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases
    • Bala S., Petrasek J., Mundkur S., et al. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology: 2012; 56 5 1946 1957
    • (2012) Hepatology , vol.56 , Issue.5 , pp. 1946-1957
    • Bala, S.1    Petrasek, J.2    Mundkur, S.3
  • 140
    • 84867002762 scopus 로고    scopus 로고
    • MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis
    • Ogawa T., Enomoto M., Fujii H., et al. MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. Gut: 2012; 61 11 1600 1609
    • (2012) Gut , vol.61 , Issue.11 , pp. 1600-1609
    • Ogawa, T.1    Enomoto, M.2    Fujii, H.3
  • 141
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang Y., Liu D., Chen X., et al. Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol Cell: 2010; 39 1 133 144
    • (2010) Mol Cell , vol.39 , Issue.1 , pp. 133-144
    • Zhang, Y.1    Liu, D.2    Chen, X.3
  • 142
    • 84873596150 scopus 로고    scopus 로고
    • Macrophage microvesicles induce macrophage differentiation and miR-223 transfer
    • Ismail N., Wang Y., Dakhlallah D., et al. Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood: 2013; 121 6 984 995
    • (2013) Blood , vol.121 , Issue.6 , pp. 984-995
    • Ismail, N.1    Wang, Y.2    Dakhlallah, D.3
  • 143
    • 84858782897 scopus 로고    scopus 로고
    • Inhibition of microRNA function by antimiR oligonucleotides
    • Stenvang J., Petri A., Lindow M., Obad S., Kauppinen S. Inhibition of microRNA function by antimiR oligonucleotides. Silence: 2012; 3 1 1
    • (2012) Silence , vol.3 , Issue.1 , pp. 1
    • Stenvang, J.1    Petri, A.2    Lindow, M.3    Obad, S.4    Kauppinen, S.5
  • 144
    • 84887185103 scopus 로고    scopus 로고
    • Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations
    • Wang X., Yu B., Ren W., et al. Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations. J Control Release: 2013; 172 3 690 698
    • (2013) J Control Release , vol.172 , Issue.3 , pp. 690-698
    • Wang, X.1    Yu, B.2    Ren, W.3
  • 145
    • 84861705805 scopus 로고    scopus 로고
    • MiR-122 in hepatic function and liver diseases
    • Hu J., Xu Y., Hao J., Wang S., Li C., Meng S. MiR-122 in hepatic function and liver diseases. Protein Cell: 2012; 3 5 364 371
    • (2012) Protein Cell , vol.3 , Issue.5 , pp. 364-371
    • Hu, J.1    Xu, Y.2    Hao, J.3    Wang, S.4    Li, C.5    Meng, S.6
  • 146
    • 84877258007 scopus 로고    scopus 로고
    • Treatment of HCV infection by targeting microRNA
    • Janssen H. L., Reesink H. W., Lawitz E. J., et al. Treatment of HCV infection by targeting microRNA. N Engl J Med: 2013; 368 18 1685 1694
    • (2013) N Engl J Med , vol.368 , Issue.18 , pp. 1685-1694
    • Janssen, H.L.1    Reesink, H.W.2    Lawitz, E.J.3
  • 147
    • 77953787211 scopus 로고    scopus 로고
    • MiR-33 contributes to the regulation of cholesterol homeostasis
    • (5985)
    • Rayner K. J., Suárez Y., Dávalos A., et al. MiR-33 contributes to the regulation of cholesterol homeostasis. Science: 2010; 328 (5985): 1570 1573
    • (2010) Science , vol.328 , pp. 1570-1573
    • Rayner, K.J.1    Suárez, Y.2    Dávalos, A.3
  • 148
    • 54249096193 scopus 로고    scopus 로고
    • MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths
    • Sayed D., Rane S., Lypowy J., et al. MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol Biol Cell: 2008; 19 8 3272 3282
    • (2008) Mol Biol Cell , vol.19 , Issue.8 , pp. 3272-3282
    • Sayed, D.1    Rane, S.2    Lypowy, J.3
  • 149
    • 84863983719 scopus 로고    scopus 로고
    • MicroRNA silencing and the development of novel therapies for liver disease
    • Szabo G., Sarnow P., Bala S. MicroRNA silencing and the development of novel therapies for liver disease. J Hepatol: 2012; 57 2 462 466
    • (2012) J Hepatol , vol.57 , Issue.2 , pp. 462-466
    • Szabo, G.1    Sarnow, P.2    Bala, S.3
  • 150
    • 38349171887 scopus 로고    scopus 로고
    • Oral delivery of antisense oligonucleotides in man
    • Tillman L. G., Geary R. S., Hardee G. E. Oral delivery of antisense oligonucleotides in man. J Pharm Sci: 2008; 97 1 225 236
    • (2008) J Pharm Sci , vol.97 , Issue.1 , pp. 225-236
    • Tillman, L.G.1    Geary, R.S.2    Hardee, G.E.3
  • 151
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman R. C., Farh K. K., Burge C. B., Bartel D. P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res: 2009; 19 1 92 105
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 152
    • 84888131014 scopus 로고    scopus 로고
    • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT
    • Choi S. E., Fu T., Seok S., et al. Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell: 2013; 12 6 1062 1072
    • (2013) Aging Cell , vol.12 , Issue.6 , pp. 1062-1072
    • Choi, S.E.1    Fu, T.2    Seok, S.3
  • 153
    • 84880925312 scopus 로고    scopus 로고
    • Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease
    • Derdak Z., Villegas K. A., Harb R., Wu A. M., Sousa A., Wands J. R. Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease. J Hepatol: 2013; 58 4 785 791
    • (2013) J Hepatol , vol.58 , Issue.4 , pp. 785-791
    • Derdak, Z.1    Villegas, K.A.2    Harb, R.3    Wu, A.M.4    Sousa, A.5    Wands, J.R.6
  • 154
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with antagomirse"
    • Krutzfeldt J., Rajewsky N., Braich R., et al. Silencing of microRNAs in vivo with antagomirs Nature: 2005; 438 7068 685 689
    • (2005) Nature , vol.438 , Issue.7068 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 155
    • 84879275954 scopus 로고    scopus 로고
    • Circulating microRNAs as a fingerprint for liver cirrhosis
    • Chen Y. J., Zhu J. M., Wu H., et al. Circulating microRNAs as a fingerprint for liver cirrhosis. PloS ONE: 2013; 8 6 e66577
    • (2013) PloS ONE , vol.8 , Issue.6 , pp. e66577
    • Chen, Y.J.1    Zhu, J.M.2    Wu, H.3


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