메뉴 건너뛰기




Volumn 9, Issue 10, 2013, Pages

MicroRNA-155 Promotes Autophagy to Eliminate Intracellular Mycobacteria by Targeting Rheb

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; BCG VACCINE; BETA ACTIN; CD63 ANTIGEN; LUCIFERASE; MICRORNA 155; MICROTUBULE ASSOCIATED PROTEIN; RAPAMYCIN; RHEB PROTEIN;

EID: 84887296519     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003697     Document Type: Article
Times cited : (220)

References (65)
  • 1
    • 77952356637 scopus 로고    scopus 로고
    • Tuberculosis: what we don't know can, and does, hurt us
    • Russell DG, Barry CE, (2010) Tuberculosis: what we don't know can, and does, hurt us. Science 328: 852-856.
    • (2010) Science , vol.328 , pp. 852-856
    • Russell, D.G.1    Barry, C.E.2
  • 4
  • 5
    • 34250222782 scopus 로고    scopus 로고
    • Host innate immune response to Mycobacterium tuberculosis
    • Bhatt K, Salgame P, (2007) Host innate immune response to Mycobacterium tuberculosis. J Clin Immunol 27: 347-362.
    • (2007) J Clin Immunol , vol.27 , pp. 347-362
    • Bhatt, K.1    Salgame, P.2
  • 6
    • 68249100525 scopus 로고    scopus 로고
    • Evasion and subversion of antigen presentation by Mycobacterium tuberculosis
    • Baena A, Porcelli SA, (2009) Evasion and subversion of antigen presentation by Mycobacterium tuberculosis. Tissue Antigens 74: 189-204.
    • (2009) Tissue Antigens , vol.74 , pp. 189-204
    • Baena, A.1    Porcelli, S.A.2
  • 7
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, et al. (2004) Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119: 753-766.
    • (2004) Cell , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5
  • 8
    • 33645542679 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism
    • Deretic V, Singh S, Master S, Harris J, Roberts E, et al. (2006) Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism. Cell Microbiol 8: 719-727.
    • (2006) Cell Microbiol , vol.8 , pp. 719-727
    • Deretic, V.1    Singh, S.2    Master, S.3    Harris, J.4    Roberts, E.5
  • 9
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G, (2008) Autophagy in the pathogenesis of disease. Cell 132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 10
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ, (2008) Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 11
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B, Klionsky DJ, (2004) Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477.
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 12
    • 58049204465 scopus 로고    scopus 로고
    • Autophagy and pattern recognition receptors in innate immunity
    • Delgado M, Singh S, De Haro S, Master S, Ponpuak M, et al. (2009) Autophagy and pattern recognition receptors in innate immunity. Immunol Rev 227: 189-202.
    • (2009) Immunol Rev , vol.227 , pp. 189-202
    • Delgado, M.1    Singh, S.2    De Haro, S.3    Master, S.4    Ponpuak, M.5
  • 14
    • 33744958258 scopus 로고    scopus 로고
    • Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
    • Birmingham CL, Smith AC, Bakowski MA, Yoshimori T, Brumell JH, (2006) Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem 281: 11374-11383.
    • (2006) J Biol Chem , vol.281 , pp. 11374-11383
    • Birmingham, C.L.1    Smith, A.C.2    Bakowski, M.A.3    Yoshimori, T.4    Brumell, J.H.5
  • 15
    • 0037711625 scopus 로고    scopus 로고
    • Cytoplasmic bacteria can be targets for autophagy
    • Rich KA, Burkett C, Webster P, (2003) Cytoplasmic bacteria can be targets for autophagy. Cell Microbiol 5: 455-468.
    • (2003) Cell Microbiol , vol.5 , pp. 455-468
    • Rich, K.A.1    Burkett, C.2    Webster, P.3
  • 16
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW, (2011) Autophagy in immunity and inflammation. Nature 469: 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 17
    • 58049198458 scopus 로고    scopus 로고
    • Toll-like receptor signaling in the lysosomal pathways
    • Sanjuan MA, Milasta S, Green DR, (2009) Toll-like receptor signaling in the lysosomal pathways. Immunol Rev 227: 203-220.
    • (2009) Immunol Rev , vol.227 , pp. 203-220
    • Sanjuan, M.A.1    Milasta, S.2    Green, D.R.3
  • 18
    • 77951256153 scopus 로고    scopus 로고
    • Autophagy in infection
    • Deretic V, (2010) Autophagy in infection. Curr Opin Cell Biol 22: 252-262.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 252-262
    • Deretic, V.1
  • 19
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: an innocent convict?
    • Levine B, Yuan J, (2005) Autophagy in cell death: an innocent convict? J Clin Invest 115: 2679-2688.
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 20
    • 84862790135 scopus 로고    scopus 로고
    • MicroRNA-modulated autophagic signaling networks in cancer
    • Fu LL, Wen X, Bao JK, Liu B, (2012) MicroRNA-modulated autophagic signaling networks in cancer. Int J Biochem Cell Biol 44: 733-736.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 733-736
    • Fu, L.L.1    Wen, X.2    Bao, J.K.3    Liu, B.4
  • 21
    • 33847311819 scopus 로고    scopus 로고
    • MicroRNAs and immunity: tiny players in a big field
    • Taganov KD, Boldin MP, Baltimore D, (2007) MicroRNAs and immunity: tiny players in a big field. Immunity 26: 133-137.
    • (2007) Immunity , vol.26 , pp. 133-137
    • Taganov, K.D.1    Boldin, M.P.2    Baltimore, D.3
  • 22
    • 80054810826 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b
    • Rajaram MV, Ni B, Morris JD, Brooks MN, Carlson TK, et al. (2011) Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. Proc Natl Acad Sci U S A 108: 17408-17413.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 17408-17413
    • Rajaram, M.V.1    Ni, B.2    Morris, J.D.3    Brooks, M.N.4    Carlson, T.K.5
  • 23
    • 79954461556 scopus 로고    scopus 로고
    • Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis
    • Liu Y, Wang X, Jiang J, Cao Z, Yang B, et al. (2011) Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. Mol Immunol 48: 1084-1090.
    • (2011) Mol Immunol , vol.48 , pp. 1084-1090
    • Liu, Y.1    Wang, X.2    Jiang, J.3    Cao, Z.4    Yang, B.5
  • 24
    • 80052033649 scopus 로고    scopus 로고
    • The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma
    • Ma F, Xu S, Liu X, Zhang Q, Xu X, et al. (2011) The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma. Nat Immunol 12: 861-869.
    • (2011) Nat Immunol , vol.12 , pp. 861-869
    • Ma, F.1    Xu, S.2    Liu, X.3    Zhang, Q.4    Xu, X.5
  • 25
    • 79959316649 scopus 로고    scopus 로고
    • Special issue of Current Opinion in Microbiology, focused on 'Ecology and Industrial Microbiology
    • Top EM, Wilson DB, (2011) Special issue of Current Opinion in Microbiology, focused on 'Ecology and Industrial Microbiology'. Curr Opin Microbiol 14: 227-228.
    • (2011) Curr Opin Microbiol , vol.14 , pp. 227-228
    • Top, E.M.1    Wilson, D.B.2
  • 27
    • 62449173209 scopus 로고    scopus 로고
    • MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
    • Ceppi M, Pereira PM, Dunand-Sauthier I, Barras E, Reith W, et al. (2009) MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci U S A 106: 2735-2740.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2735-2740
    • Ceppi, M.1    Pereira, P.M.2    Dunand-Sauthier, I.3    Barras, E.4    Reith, W.5
  • 28
    • 14844354250 scopus 로고    scopus 로고
    • Accumulation of miR-155 and BIC RNA in human B cell lymphomas
    • Eis PS, Tam W, Sun L, Chadburn A, Li Z, et al. (2005) Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci U S A 102: 3627-3632.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3627-3632
    • Eis, P.S.1    Tam, W.2    Sun, L.3    Chadburn, A.4    Li, Z.5
  • 29
    • 18744416255 scopus 로고    scopus 로고
    • T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC
    • Haasch D, Chen YW, Reilly RM, Chiou XG, Koterski S, et al. (2002) T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC. Cell Immunol 217: 78-86.
    • (2002) Cell Immunol , vol.217 , pp. 78-86
    • Haasch, D.1    Chen, Y.W.2    Reilly, R.M.3    Chiou, X.G.4    Koterski, S.5
  • 30
    • 70349436102 scopus 로고    scopus 로고
    • Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response
    • Xiao B, Liu Z, Li BS, Tang B, Li W, et al. (2009) Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. J Infect Dis 200: 916-925.
    • (2009) J Infect Dis , vol.200 , pp. 916-925
    • Xiao, B.1    Liu, Z.2    Li, B.S.3    Tang, B.4    Li, W.5
  • 32
    • 84355162842 scopus 로고    scopus 로고
    • Analysis of microRNA expression profiling identifies miR-155 and miR-155* as potential diagnostic markers for active tuberculosis: a preliminary study
    • Wu J, Lu C, Diao N, Zhang S, Wang S, et al. (2012) Analysis of microRNA expression profiling identifies miR-155 and miR-155* as potential diagnostic markers for active tuberculosis: a preliminary study. Hum Immunol 73: 31-37.
    • (2012) Hum Immunol , vol.73 , pp. 31-37
    • Wu, J.1    Lu, C.2    Diao, N.3    Zhang, S.4    Wang, S.5
  • 34
    • 34247584465 scopus 로고    scopus 로고
    • Requirement of bic/microRNA-155 for normal immune function
    • Rodriguez A, Vigorito E, Clare S, Warren MV, Couttet P, et al. (2007) Requirement of bic/microRNA-155 for normal immune function. Science 316: 608-611.
    • (2007) Science , vol.316 , pp. 608-611
    • Rodriguez, A.1    Vigorito, E.2    Clare, S.3    Warren, M.V.4    Couttet, P.5
  • 35
    • 77958495102 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
    • O'Connell RM, Kahn D, Gibson WS, Round JL, Scholz RL, et al. (2010) MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 33: 607-619.
    • (2010) Immunity , vol.33 , pp. 607-619
    • O'Connell, R.M.1    Kahn, D.2    Gibson, W.S.3    Round, J.L.4    Scholz, R.L.5
  • 36
    • 80555127350 scopus 로고    scopus 로고
    • MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
    • Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, et al. (2011) MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 44: 424-436.
    • (2011) Mol Cell , vol.44 , pp. 424-436
    • Suzuki, H.I.1    Arase, M.2    Matsuyama, H.3    Choi, Y.L.4    Ueno, T.5
  • 38
    • 48549100053 scopus 로고    scopus 로고
    • Human macrophage host defense against Mycobacterium tuberculosis
    • Liu PT, Modlin RL, (2008) Human macrophage host defense against Mycobacterium tuberculosis. Curr Opin Immunol 20: 371-376.
    • (2008) Curr Opin Immunol , vol.20 , pp. 371-376
    • Liu, P.T.1    Modlin, R.L.2
  • 39
    • 0023934091 scopus 로고
    • Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex
    • Bermudez LE, Young LS, (1988) Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex. J Immunol 140: 3006-3013.
    • (1988) J Immunol , vol.140 , pp. 3006-3013
    • Bermudez, L.E.1    Young, L.S.2
  • 40
    • 0028979703 scopus 로고
    • Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
    • Flynn JL, Goldstein MM, Chan J, Triebold KJ, Pfeffer K, et al. (1995) Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2: 561-572.
    • (1995) Immunity , vol.2 , pp. 561-572
    • Flynn, J.L.1    Goldstein, M.M.2    Chan, J.3    Triebold, K.J.4    Pfeffer, K.5
  • 41
    • 0031133280 scopus 로고    scopus 로고
    • Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages
    • Fratazzi C, Arbeit RD, Carini C, Remold HG, (1997) Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages. J Immunol 158: 4320-4327.
    • (1997) J Immunol , vol.158 , pp. 4320-4327
    • Fratazzi, C.1    Arbeit, R.D.2    Carini, C.3    Remold, H.G.4
  • 42
    • 33646027045 scopus 로고    scopus 로고
    • Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway
    • Lee J, Remold HG, Ieong MH, Kornfeld H, (2006) Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway. J Immunol 176: 4267-4274.
    • (2006) J Immunol , vol.176 , pp. 4267-4274
    • Lee, J.1    Remold, H.G.2    Ieong, M.H.3    Kornfeld, H.4
  • 43
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • Levine B, Deretic V, (2007) Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 7: 767-777.
    • (2007) Nat Rev Immunol , vol.7 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 44
    • 79955750977 scopus 로고    scopus 로고
    • Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis
    • Herbst S, Schaible UE, Schneider BE, (2011) Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis. PLoS One 6: e19105.
    • (2011) PLoS One , vol.6
    • Herbst, S.1    Schaible, U.E.2    Schneider, B.E.3
  • 45
    • 62049084947 scopus 로고    scopus 로고
    • Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    • Jagannath C, Lindsey DR, Dhandayuthapani S, Xu Y, Hunter RL Jr, et al. (2009) Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med 15: 267-276.
    • (2009) Nat Med , vol.15 , pp. 267-276
    • Jagannath, C.1    Lindsey, D.R.2    Dhandayuthapani, S.3    Xu, Y.4    Hunter Jr., R.L.5
  • 46
    • 84861180818 scopus 로고    scopus 로고
    • Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action
    • Kim JJ, Lee HM, Shin DM, Kim W, Yuk JM, et al. (2012) Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. Cell Host Microbe 11: 457-468.
    • (2012) Cell Host Microbe , vol.11 , pp. 457-468
    • Kim, J.J.1    Lee, H.M.2    Shin, D.M.3    Kim, W.4    Yuk, J.M.5
  • 47
    • 0035936836 scopus 로고    scopus 로고
    • Induction of direct antimicrobial activity through mammalian toll-like receptors
    • Thoma-Uszynski S, Stenger S, Takeuchi O, Ochoa MT, Engele M, et al. (2001) Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 291: 1544-1547.
    • (2001) Science , vol.291 , pp. 1544-1547
    • Thoma-Uszynski, S.1    Stenger, S.2    Takeuchi, O.3    Ochoa, M.T.4    Engele, M.5
  • 48
    • 33845899377 scopus 로고    scopus 로고
    • Requirement of tumor necrosis factor alpha and nuclear factor-kappaB in the induction by IFN-gamma of inducible nitric oxide synthase in macrophages
    • Vila-del Sol V, Diaz-Munoz MD, Fresno M, (2007) Requirement of tumor necrosis factor alpha and nuclear factor-kappaB in the induction by IFN-gamma of inducible nitric oxide synthase in macrophages. J Leukoc Biol 81: 272-283.
    • (2007) J Leukoc Biol , vol.81 , pp. 272-283
    • Vila-del Sol, V.1    Diaz-Munoz, M.D.2    Fresno, M.3
  • 49
    • 84866893356 scopus 로고    scopus 로고
    • Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors
    • Dharmaraja AT, Alvala M, Sriram D, Yogeeswari P, Chakrapani H, (2012) Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors. Chem Commun (Camb) 48: 10325-10327.
    • (2012) Chem Commun (Camb) , vol.48 , pp. 10325-10327
    • Dharmaraja, A.T.1    Alvala, M.2    Sriram, D.3    Yogeeswari, P.4    Chakrapani, H.5
  • 50
    • 78650658467 scopus 로고    scopus 로고
    • Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1
    • Wang P, Hou J, Lin L, Wang C, Liu X, et al. (2010) Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J Immunol 185: 6226-6233.
    • (2010) J Immunol , vol.185 , pp. 6226-6233
    • Wang, P.1    Hou, J.2    Lin, L.3    Wang, C.4    Liu, X.5
  • 51
    • 37049002638 scopus 로고    scopus 로고
    • microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells
    • Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, et al. (2007) microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 27: 847-859.
    • (2007) Immunity , vol.27 , pp. 847-859
    • Vigorito, E.1    Perks, K.L.2    Abreu-Goodger, C.3    Bunting, S.4    Xiang, Z.5
  • 52
    • 41149130219 scopus 로고    scopus 로고
    • Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
    • O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, et al. (2008) Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205: 585-594.
    • (2008) J Exp Med , vol.205 , pp. 585-594
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Boldin, M.P.4    Taganov, K.D.5
  • 54
    • 77951294330 scopus 로고    scopus 로고
    • Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation
    • Tang B, Xiao B, Liu Z, Li N, Zhu ED, et al. (2010) Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. FEBS Lett 584: 1481-1486.
    • (2010) FEBS Lett , vol.584 , pp. 1481-1486
    • Tang, B.1    Xiao, B.2    Liu, Z.3    Li, N.4    Zhu, E.D.5
  • 55
    • 84862660781 scopus 로고    scopus 로고
    • Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma
    • Huang X, Shen Y, Liu M, Bi C, Jiang C, et al. (2012) Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. Am J Pathol 181: 26-33.
    • (2012) Am J Pathol , vol.181 , pp. 26-33
    • Huang, X.1    Shen, Y.2    Liu, M.3    Bi, C.4    Jiang, C.5
  • 56
    • 84872155023 scopus 로고    scopus 로고
    • Diverse functions of miR-125 family in different cell contexts
    • Sun YM, Lin KY, Chen YQ, (2013) Diverse functions of miR-125 family in different cell contexts. J Hematol Oncol 6: 6.
    • (2013) J Hematol Oncol , vol.6 , pp. 6
    • Sun, Y.M.1    Lin, K.Y.2    Chen, Y.Q.3
  • 57
    • 84862805764 scopus 로고    scopus 로고
    • MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression
    • Zhao A, Zeng Q, Xie X, Zhou J, Yue W, et al. (2012) MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. J Genet Genomics 39: 29-35.
    • (2012) J Genet Genomics , vol.39 , pp. 29-35
    • Zhao, A.1    Zeng, Q.2    Xie, X.3    Zhou, J.4    Yue, W.5
  • 58
    • 84863355999 scopus 로고    scopus 로고
    • Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways
    • Zeng CW, Zhang XJ, Lin KY, Ye H, Feng SY, et al. (2012) Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Mol Pharmacol 81: 578-586.
    • (2012) Mol Pharmacol , vol.81 , pp. 578-586
    • Zeng, C.W.1    Zhang, X.J.2    Lin, K.Y.3    Ye, H.4    Feng, S.Y.5
  • 59
    • 0038433304 scopus 로고    scopus 로고
    • Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
    • Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, et al. (2003) Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol Cell 11: 1457-1466.
    • (2003) Mol Cell , vol.11 , pp. 1457-1466
    • Garami, A.1    Zwartkruis, F.J.2    Nobukuni, T.3    Joaquin, M.4    Roccio, M.5
  • 60
    • 84863590701 scopus 로고    scopus 로고
    • Hepatitis C virus activates the mTOR/S6K1 signaling pathway in inhibiting IRS-1 function for insulin resistance
    • Bose SK, Shrivastava S, Meyer K, Ray RB, Ray R, (2012) Hepatitis C virus activates the mTOR/S6K1 signaling pathway in inhibiting IRS-1 function for insulin resistance. J Virol 86: 6315-6322.
    • (2012) J Virol , vol.86 , pp. 6315-6322
    • Bose, S.K.1    Shrivastava, S.2    Meyer, K.3    Ray, R.B.4    Ray, R.5
  • 61
    • 79952424876 scopus 로고    scopus 로고
    • Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb in GSH-depleted RAW 264.7 cells
    • Seo G, Kim SK, Byun YJ, Oh E, Jeong SW, et al. (2011) Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb in GSH-depleted RAW 264.7 cells. Free Radic Res 45: 389-399.
    • (2011) Free Radic Res , vol.45 , pp. 389-399
    • Seo, G.1    Kim, S.K.2    Byun, Y.J.3    Oh, E.4    Jeong, S.W.5
  • 62
    • 84862301902 scopus 로고    scopus 로고
    • Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program
    • Tattoli I, Sorbara MT, Vuckovic D, Ling A, Soares F, et al. (2012) Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host Microbe 11: 563-575.
    • (2012) Cell Host Microbe , vol.11 , pp. 563-575
    • Tattoli, I.1    Sorbara, M.T.2    Vuckovic, D.3    Ling, A.4    Soares, F.5
  • 63
    • 53849119118 scopus 로고    scopus 로고
    • Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism
    • Liao XH, Majithia A, Huang X, Kimmel AR, (2008) Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism. Amino Acids 35: 761-770.
    • (2008) Amino Acids , vol.35 , pp. 761-770
    • Liao, X.H.1    Majithia, A.2    Huang, X.3    Kimmel, A.R.4
  • 64
    • 38049050178 scopus 로고    scopus 로고
    • Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls
    • Tanida I, Yamaji T, Ueno T, Ishiura S, Kominami E, et al. (2008) Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls. Autophagy 4: 131-134.
    • (2008) Autophagy , vol.4 , pp. 131-134
    • Tanida, I.1    Yamaji, T.2    Ueno, T.3    Ishiura, S.4    Kominami, E.5
  • 65
    • 0032755561 scopus 로고    scopus 로고
    • Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa
    • Mariencheck WI, Savov J, Dong Q, Tino MJ, Wright JR, (1999) Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa. Am J Physiol 277: L777-786.
    • (1999) Am J Physiol , vol.277
    • Mariencheck, W.I.1    Savov, J.2    Dong, Q.3    Tino, M.J.4    Wright, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.