Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis

Liver International

Volumn 33, Issue 8, 2013, Pages 1257-1265

  Chen, Yi Peng ^a   Jin, Xi ^a   Xiang, Zun ^a   Chen, Shao Hua ^a   Li, You Ming ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Microarray; MiR 21; qRT PCR; Serum miRNA

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 214; PROTEIN KINASE LYN; STAT3 PROTEIN;

ALCOHOLIC FATTY LIVER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; CASE REPORT; CONTROLLED STUDY; FATTY ACID METABOLISM; HUMAN; NONHUMAN; RANDOMIZED CONTROLLED TRIAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

MICROARRAY; MIR-21; QRT-PCR; SERUM MIRNA;

ANIMALS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DISEASE MODELS, ANIMAL; FATTY LIVER, ALCOHOLIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE ONTOLOGY; GENE REGULATORY NETWORKS; GENETIC MARKERS; GENETIC TESTING; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84881554943     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12196     Document Type: Article

References (47)

1. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Hepatology 2010; 51: 307-28.
2. Beier JI, McClain CJ. Mechanisms and cell signaling in alcoholic liver disease. Biol Chem 2010; 391: 1249-64.
3. Gao B, Bataller R: Alcoholic Liver Disease: pathogenesis and New Therapeutic Targets. Gastroenterology 2011; 141: 1572-85.
4. Deltenre P, Mathurin P. Epidemiology of alcoholic liver disease and new challenges. Gastroenterol Clin Biol 2009; 33: 1147-50.
5. Li YM, Fan JG, Wang BY, et al. Guidelines for the diagnosis and management of alcoholic liver disease: update 2010: (published in Chinese on Chinese Journal of Hepatology 2010; 18: 167-170). J Dig Dis 2011; 12: 45-50.
6. Lau NC, Lim LP, Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001; 294: 858-62.
7. Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-55.
8. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-54.
9. Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 2000; 408: 86-9.
10. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-66.
11. Jin X, Ye YF, Chen SH, et al. MicroRNA expression pattern in different stages of nonalcoholic fatty liver disease. Dig Liver Dis 2009; 41: 289-97.
12. Marcucci G, Radmacher MD, Mrozek K, Bloomfield CD. MicroRNA expression in acute myeloid leukemia. Curr Hematol Malig Rep 2009; 4: 83-8.
13. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
14. Lawrie CH, Gal S, Dunlop HM, et al. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol 2008; 141: 672-75.
15. Chen X, Ba Y, Ma L, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008; 18: 997-1006.
16. Brase JC, Wuttig D, Kuner R, Sultmann H. Serum microRNAs as non-invasive biomarkers for cancer. Mol Cancer 2010; 9: 306.
17. Wang K, Zhang S, Marzolf B, et al. Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A 2009; 106: 4402-07.
18. Wang JF, Yu ML, Yu G, et al. Serum miR-146a and miR-223 as potential new biomarkers for sepsis. Biochem Biophys Res Commun 2010; 394: 184-88.
19. Zhang XG, Xu P, Liu Q, et al. Effect of tea polyphenol on cytokine gene expression in rats with alcoholic liver disease. Hepatobiliary Pancreat Dis Int 2006; 5: 268-72.
20. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999; 94: 2467-74.
21. Chen C, Ridzon DA, Broomer AJ, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 2005; 33: e179.
22. Griffiths-Jones S. The microRNA Registry. Nucleic Acids Res 2004, 32(Database issue):D109-11.
23. Olson NE. The microarray data analysis process: from raw data to biological significance. NeuroRx 2006; 3: 373-83.
24. Tibshirani R, Hastie T, Narasimhan B, Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A 2002; 99: 6567-72.
25. Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A 1998; 95: 14863-8.
26. Shen E, Diao X, Wei C, et al. MicroRNAs target gene and signaling pathway by bioinformatics analysis in the cardiac hypertrophy. Biochem Biophys Res Commun 2010; 397: 380-85.
27. Guo CJ, Pan Q, Cheng T, et al. Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways. FEBS J 2009; 276: 5163-76.
28. Mandrekar P. Epigenetic regulation in alcoholic liver disease. World J Gastroenterol 2011; 17: 2456-64.
29. Dolganiuc A, Petrasek J, Kodys K, et al. MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. Alcohol Clin Exp Res 2009; 33: 1704-10.
30. Mitchell PS, Parkin RK, Kroh EM, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 2008; 105: 10513-18.
31. Suwannalai P, Willemze A, van Toorn L, et al. TW JH, RE MT, Trouw LA: the fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA. Arthritis Res Ther 2011; 13: R195.
32. Liu M, Lang N, Chen X, et al. miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells. Cancer Lett 2011; 301: 151-60.
33. Zhang XJ, Ye H, Zeng CW, et al. Dysregulation of miR-15a and miR-214 in human pancreatic cancer. J Hematol Oncol 2010; 3: 46.
34. Yang H, Kong W, He L, et al. MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res 2008; 68: 425-33.
35. Shatseva T, Lee DY, Deng Z, Yang BB. MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. J Cell Sci 2011; 124: 2826-36.
36. Fornari F, Milazzo M, Chieco P, et al. MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res 2010; 70: 5184-93.
37. Cowan ML, Vera J. Proteomics: advances in biomarker discovery. Expert Rev Proteomics 2008; 5: 21-3.
38. Ebert MP, Korc M, Malfertheiner P, Rocken C. Advances, challenges, and limitations in serum-proteome-based cancer diagnosis. J Proteome Res 2006; 5: 19-25.
39. Ji X, Takahashi R, Hiura Y, et al. Plasma miR-208 as a biomarker of myocardial injury. Clin Chem 2009; 55: 1944-49.
40. Valadi H, Ekstrom K, Bossios A, et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007; 9: 654-59.
41. Kosaka N, Iguchi H, Yoshioka Y, et al. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem 2010; 285: 17442-52.
42. Barth JL, Clark CD, Fresco VM, et al. Jarid2 is among a set of genes differentially regulated by Nkx2.5 during outflow tract morphogenesis. Dev Dyn 2010; 239: 2024-33.
43. Roginski RS, Goubaeva F, Mikami M, et al. GRINL1A colocalizes with N-methyl D-aspartate receptor NR1 subunit and reduces N-methyl D-aspartate toxicity. NeuroReport 2008; 19: 1721-16.
44. Scapini P, Pereira S, Zhang H, Lowell CA. Multiple roles of Lyn kinase in myeloid cell signaling and function. Immunol Rev 2009; 228: 23-40.
45. Gringeri E, Carraro A, Tibaldi E, et al. Lyn-mediated mitochondrial tyrosine phosphorylation is required to preserve mitochondrial integrity in early liver regeneration. Biochem J 2010; 425: 401-12.
46. Gupta RK, Mepani RJ, Kleiner S, et al. Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab 2012; 15: 230-39.
47. Masserdotti G, Badaloni A, Green YS, et al. ZFP423 coordinates Notch and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. J Biol Chem 2010; 285: 30814-24.