메뉴 건너뛰기




Volumn 12, Issue 1, 2013, Pages

MicroRNA-613 represses lipogenesis in HepG2 cells by downregulating LXRα

Author keywords

HepG2 cells; Lipogenesis; Liver X receptor ; microRNA 613

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; FAT DROPLET; FATTY ACID SYNTHASE; LIVER X RECEPTOR ALPHA; LUCIFERASE; MICRORNA; MICRORNA 613; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG;

EID: 84874715904     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-12-32     Document Type: Article
Times cited : (49)

References (27)
  • 1
    • 80052099673 scopus 로고    scopus 로고
    • MicroRNAs in beta-cell biology, insulin resistance, diabetes and its complications
    • 10.2337/db11-0171 21709277
    • MicroRNAs in beta-cell biology, insulin resistance, diabetes and its complications. Fernandez-Valverde SL, Taft RJ, Mattick JS, Diabetes 2011 60 7 1825 1831 10.2337/db11-0171 21709277
    • (2011) Diabetes , vol.60 , Issue.7 , pp. 1825-1831
    • Fernandez-Valverde, S.L.1    Taft, R.J.2    Mattick, J.S.3
  • 2
    • 82255162676 scopus 로고    scopus 로고
    • MicroRNA involvement in esophageal carcinogenesis
    • 10.1016/j.coph.2011.09.006 21992930
    • MicroRNA involvement in esophageal carcinogenesis. David S, Meltzer SJ, Curr Opin Pharmacol 2011 11 6 612 616 10.1016/j.coph.2011.09.006 21992930
    • (2011) Curr Opin Pharmacol , vol.11 , Issue.6 , pp. 612-616
    • David, S.1    Meltzer, S.J.2
  • 3
    • 77649339454 scopus 로고    scopus 로고
    • MicroRNA and vascular smooth muscle cell phenotype: New therapy for atherosclerosis?
    • 10.1186/gm85 19744308
    • MicroRNA and vascular smooth muscle cell phenotype: new therapy for atherosclerosis? Zhang C, Genome Med 2009 1 9 85 10.1186/gm85 19744308
    • (2009) Genome Med , vol.1 , Issue.9 , pp. 85
    • Zhang, C.1
  • 4
    • 84861093038 scopus 로고    scopus 로고
    • MicroRNAs: Emerging roles in lipid and lipoprotein metabolism
    • 10.1097/MOL.0b013e3283534c9f 22488426
    • MicroRNAs: emerging roles in lipid and lipoprotein metabolism. Sacco J, Adeli K, Curr Opin Lipidol 2012 23 3 220 225 10.1097/MOL.0b013e3283534c9f 22488426
    • (2012) Curr Opin Lipidol , vol.23 , Issue.3 , pp. 220-225
    • Sacco, J.1    Adeli, K.2
  • 6
    • 79960523356 scopus 로고    scopus 로고
    • The role of microRNAs in cholesterol efflux and hepatic lipid metabolism
    • 10.1146/annurev-nutr-081810-160756 21548778
    • The role of microRNAs in cholesterol efflux and hepatic lipid metabolism. Moore KJ, Rayner KJ, Suarez Y, Fernandez-Hernando C, Annu Rev Nutr 2011 31 49 63 10.1146/annurev-nutr-081810-160756 21548778
    • (2011) Annu Rev Nutr , vol.31 , pp. 49-63
    • Moore, K.J.1    Rayner, K.J.2    Suarez, Y.3    Fernandez-Hernando, C.4
  • 7
    • 80054773989 scopus 로고    scopus 로고
    • A systematic screen for micro-RNAs regulating the canonical Wnt pathway
    • 10.1371/journal.pone.0026257 22043311
    • A systematic screen for micro-RNAs regulating the canonical Wnt pathway. Anton R, Chatterjee SS, Simundza J, Cowin P, Dasgupta R, PLoS One 2011 6 10 26257 10.1371/journal.pone.0026257 22043311
    • (2011) PLoS One , vol.6 , Issue.10 , pp. 526257
    • Anton, R.1    Chatterjee, S.S.2    Simundza, J.3    Cowin, P.4    Dasgupta, R.5
  • 8
    • 79953737607 scopus 로고    scopus 로고
    • MicroRNA hsa-miR-613 targets the human LXRalpha gene and mediates a feedback loop of LXRalpha autoregulation
    • 10.1210/me.2010-0360 21310851
    • MicroRNA hsa-miR-613 targets the human LXRalpha gene and mediates a feedback loop of LXRalpha autoregulation. Ou Z, Wada T, Gramignoli R, Li S, Strom SC, Huang M, Xie W, Mol Endocrinol 2011 25 4 584 596 10.1210/me.2010-0360 21310851
    • (2011) Mol Endocrinol , vol.25 , Issue.4 , pp. 584-596
    • Ou, Z.1    Wada, T.2    Gramignoli, R.3    Li, S.4    Strom, S.C.5    Huang, M.6    Xie, W.7
  • 9
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • DOI 10.1146/annurev.cellbio.16.1.459
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Repa JJ, Mangelsdorf DJ, Annu Rev Cell Dev Biol 2000 16 459 481 10.1146/annurev.cellbio.16.1.459 11031244 (Pubitemid 32037514)
    • (2000) Annual Review of Cell and Developmental Biology , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 10
    • 3843061127 scopus 로고    scopus 로고
    • Central role for liver X receptor in insulin-mediated activation of SREBP-1c transcription and stimulation of fatty acid synthesis in liver
    • DOI 10.1073/pnas.0404297101
    • Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver. Chen G, Liang G, Ou J, Goldstein JL, Brown MS, Proc Natl Acad Sci U S A 2004 101 31 11245 11250 10.1073/pnas.0404297101 15266058 (Pubitemid 39038332)
    • (2004) Proceedings of the National Academy of Sciences of the United States of America , vol.101 , Issue.31 , pp. 11245-11250
    • Chen, G.1    Liang, G.2    Ou, J.3    Goldstein, J.L.4    Brown, M.S.5
  • 11
    • 33847006599 scopus 로고    scopus 로고
    • The Liver X Receptor (LXR) and hepatic lipogenesis: The carbohydrate-response element-binding protein is a target gene of LXR
    • DOI 10.1074/jbc.M605023200
    • The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. Cha JY, Repa JJ, J Biol Chem 2007 282 1 743 751 17107947 (Pubitemid 47076632)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 743-751
    • Cha, J.-Y.1    Repa, J.J.2
  • 13
    • 33845586243 scopus 로고    scopus 로고
    • The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317
    • DOI 10.1194/jlr.M600276-JLR200
    • The mechanism mediating the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317. Talukdar S, Hillgartner FB, J Lipid Res 2006 47 11 2451 2461 10.1194/jlr.M600276-JLR200 16931873 (Pubitemid 44936107)
    • (2006) Journal of Lipid Research , vol.47 , Issue.11 , pp. 2451-2461
    • Talukdar, S.1    Hillgartner, F.B.2
  • 14
    • 84862250880 scopus 로고    scopus 로고
    • Involvement of liver X receptor alpha in histone modifications across the target fatty acid synthase gene
    • 10.1007/s11745-011-3635-0 22160584
    • Involvement of liver X receptor alpha in histone modifications across the target fatty acid synthase gene. Yu H, Wu J, Yang M, Guo J, Zheng L, Peng M, Zhang Q, Xiang Y, Cao J, Shen W, Lipids 2012 47 3 249 257 10.1007/s11745-011- 3635-0 22160584
    • (2012) Lipids , vol.47 , Issue.3 , pp. 249-257
    • Yu, H.1    Wu, J.2    Yang, M.3    Guo, J.4    Zheng, L.5    Peng, M.6    Zhang, Q.7    Xiang, Y.8    Cao, J.9    Shen, W.10
  • 15
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • DOI 10.1016/S0092-8674(01)00240-9
    • Obesity and the regulation of energy balance. Spiegelman BM, Flier JS, Cell 2001 104 4 531 543 10.1016/S0092-8674(01)00240-9 11239410 (Pubitemid 32201948)
    • (2001) Cell , vol.104 , Issue.4 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 18
    • 84866552363 scopus 로고    scopus 로고
    • Relationship between Nonalcoholic Fatty Liver Disease and Carotid Artery Atherosclerosis beyond Metabolic Disorders in Non-Diabetic Patients
    • 10.4250/jcu.2012.20.3.126 23185655
    • Relationship between Nonalcoholic Fatty Liver Disease and Carotid Artery Atherosclerosis Beyond Metabolic Disorders in Non-Diabetic Patients. Kang JH, Cho KI, Kim SM, Lee JY, Kim JJ, Goo JJ, Kim KN, Jhi JH, Kim DJ, Lee HG, J Cardiovasc Ultrasound 2012 20 3 126 133 10.4250/jcu.2012.20.3.126 23185655
    • (2012) J Cardiovasc Ultrasound , vol.20 , Issue.3 , pp. 126-133
    • Kang, J.H.1    Cho, K.I.2    Kim, S.M.3    Lee, J.Y.4    Kim, J.J.5    Goo, J.J.6    Kim, K.N.7    Jhi, J.H.8    Kim, D.J.9    Lee, H.G.10
  • 19
    • 58449103541 scopus 로고    scopus 로고
    • Expression patterns of microRNAs in the chorioamniotic membranes: A role for microRNAs in human pregnancy and parturition
    • 10.1002/path.2463 18991333
    • Expression patterns of microRNAs in the chorioamniotic membranes: a role for microRNAs in human pregnancy and parturition. Montenegro D, Romero R, Kim SS, Tarca AL, Draghici S, Kusanovic JP, Kim JS, Lee DC, Erez O, Gotsch F, J Pathol 2009 217 1 113 121 10.1002/path.2463 18991333
    • (2009) J Pathol , vol.217 , Issue.1 , pp. 113-121
    • Montenegro, D.1    Romero, R.2    Kim, S.S.3    Tarca, A.L.4    Draghici, S.5    Kusanovic, J.P.6    Kim, J.S.7    Lee, D.C.8    Erez, O.9    Gotsch, F.10
  • 20
    • 78649375395 scopus 로고    scopus 로고
    • Translational regulation of gene expression during conditions of cell stress
    • 10.1016/j.molcel.2010.09.028 20965418
    • Translational regulation of gene expression during conditions of cell stress. Spriggs KA, Bushell M, Willis AE, Mol Cell 2010 40 2 228 237 10.1016/j.molcel.2010.09.028 20965418
    • (2010) Mol Cell , vol.40 , Issue.2 , pp. 228-237
    • Spriggs, K.A.1    Bushell, M.2    Willis, A.E.3
  • 21
    • 80054763773 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation
    • 10.1002/path.2962 21984125
    • Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation. Kang JG, Majerciak V, Uldrick TS, Wang X, Kruhlak M, Yarchoan R, Zheng ZM, J Pathol 2011 225 3 378 389 10.1002/path.2962 21984125
    • (2011) J Pathol , vol.225 , Issue.3 , pp. 378-389
    • Kang, J.G.1    Majerciak, V.2    Uldrick, T.S.3    Wang, X.4    Kruhlak, M.5    Yarchoan, R.6    Zheng, Z.M.7
  • 22
    • 84865305956 scopus 로고    scopus 로고
    • Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity
    • 10.1111/j.1600-065X.2012.01153.x 22889216
    • Liver X receptor and peroxisome proliferator-activated receptor as integrators of lipid homeostasis and immunity. Kidani Y, Bensinger SJ, Immunol Rev 2012 249 1 72 83 10.1111/j.1600-065X.2012.01153.x 22889216
    • (2012) Immunol Rev , vol.249 , Issue.1 , pp. 72-83
    • Kidani, Y.1    Bensinger, S.J.2
  • 23
    • 54549090146 scopus 로고    scopus 로고
    • The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation
    • 10.3181/0802-MR-50
    • The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation. Wada T, Kang HS, Jetten AM, Xie W, Exp Biol Med (Maywood) 2008 233 10 1191 1201 10.3181/0802-MR-50
    • (2008) Exp Biol Med (Maywood) , vol.233 , Issue.10 , pp. 1191-1201
    • Wada, T.1    Kang, H.S.2    Jetten, A.M.3    Xie, W.4
  • 24
    • 42449134947 scopus 로고    scopus 로고
    • Protein kinase C α modulates liver X receptor α transactivation
    • DOI 10.1677/JOE-07-0525
    • Protein kinase C alpha modulates liver X receptor alpha transactivation. Delvecchio CJ, Capone JP, J Endocrinol 2008 197 1 121 130 10.1677/JOE-07-0525 18372238 (Pubitemid 351566931)
    • (2008) Journal of Endocrinology , vol.197 , Issue.1 , pp. 121-130
    • Delvecchio, C.J.1    Capone, J.P.2
  • 25
    • 84864301367 scopus 로고    scopus 로고
    • Sterol-dependent nuclear import of ORP1S promotes LXR regulated trans-activation of apoE
    • 10.1016/j.yexcr.2012.06.012 22728266
    • Sterol-dependent nuclear import of ORP1S promotes LXR regulated trans-activation of apoE. Lee S, Wang PY, Jeong Y, Mangelsdorf DJ, Anderson RG, Michaely P, Exp Cell Res 2012 318 16 2128 2142 10.1016/j.yexcr.2012.06.012 22728266
    • (2012) Exp Cell Res , vol.318 , Issue.16 , pp. 2128-2142
    • Lee, S.1    Wang, P.Y.2    Jeong, Y.3    Mangelsdorf, D.J.4    Anderson, R.G.5    Michaely, P.6
  • 27
    • 70349191359 scopus 로고    scopus 로고
    • Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes
    • 10.1016/j.molcel.2009.07.021 19782030
    • Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes. Lee JH, Park SM, Kim OS, Lee CS, Woo JH, Park SJ, Joe EH, Jou I, Mol Cell 2009 35 6 806 817 10.1016/j.molcel.2009.07.021 19782030
    • (2009) Mol Cell , vol.35 , Issue.6 , pp. 806-817
    • Lee, J.H.1    Park, S.M.2    Kim, O.S.3    Lee, C.S.4    Woo, J.H.5    Park, S.J.6    Joe, E.H.7    Jou, I.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.