A regulatory role for microRNA 33* in controlling lipid metabolism gene expression

Molecular and Cellular Biology

Volumn 33, Issue 11, 2013, Pages 2339-2352

  Goedeke, Leigh ^a   Vales Lara, Frances M ^a   Fenstermaker, Michael ^a   Cirera Salinas, Daniel ^a   Chamorro Jorganes, Aranzazu ^a   Ramírez, Cristina M ^a   Mattison, Julie A ^b   De Cabo, Rafael ^b   Suárez, Yajaira ^a   Fernández Hernando, Carlos ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; MICRORNA; MICRORNA 33A; MICRORNA 33B; RECEPTOR INTERACTING PROTEIN 140; STEROID RECEPTOR COACTIVATOR 1; STEROID RECEPTOR COACTIVATOR 3; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FATTY ACID METABOLISM; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

3' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; CELL LINE; CONSERVED SEQUENCE; FATTY ACIDS; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; LIVER; MACACA MULATTA; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICRORNAS;

PRIMATES;

EID: 84878958446     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01714-12     Document Type: Article

References (42)

1. Bartel DP. 2009. MicroRNAs: target recognition and regulatory functions. Cell 136:215-233.
2. Ambros V. 2004. The functions of animal microRNAs. Nature 431:350-355.
3. Filipowicz W, Bhattacharyya SN, Sonenberg N. 2008. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9:102-114.
4. Khvorova A, Reynolds A, Jayasena SD. 2003. Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209 -216.
5. Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208.
6. Mah SM, Buske C, Humphries RK, Kuchenbauer F. 2010. miRNA*: a passenger stranded in RNA-induced silencing complex? Crit. Rev. Eukaryot. Gene Expr. 20:141-148.
7. Yang JS, Phillips MD, Betel D, Mu P, Ventura A, Siepel AC, Chen KC, Lai EC. 2011. Widespread regulatory activity of vertebrate microRNA* species. RNA 17:312-326.
8. Okamura K, Phillips MD, Tyler DM, Duan H, Chou YT, Lai EC. 2008. The regulatory activity of microRNA* species has substantial influence on microRNA and 3= UTR evolution. Nat. Struct. Mol. Biol. 15:354 -363.
9. Czech B, Malone CD, Zhou R, Stark A, Schlingeheyde C, Dus M, Perrimon N, Kellis M, Wohlschlegel JA, Sachidanandam R, Hannon GJ, Brennecke J. 2008. An endogenous small interfering RNA pathway in Drosophila. Nature 453:798-802.
10. Czech B, Zhou R, Erlich Y, Brennecke J, Binari R, Villalta C, Gordon A, Perrimon N, Hannon GJ. 2009. Hierarchical rules for Argonaute loading in Drosophila. Mol. Cell 36:445-456.
11. Schulte JH, Marschall T, Martin M, Rosenstiel P, Mestdagh P, Schlierf S, Thor T, Vandesompele J, Eggert A, Schreiber S, Rahmann S, Schramm A. 2010. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic Acids Res. 38:5919 -5928.
12. Okamura K, Liu N, Lai EC. 2009. Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol. Cell 36:431-444.
13. Ro S, Park C, Young D, Sanders KM, Yan W. 2007. Tissue-dependent paired expression of miRNAs. Nucleic Acids Res. 35:5944 -5953.
14. Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. 2010. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev. 24:992-1009.
15. Goff LA, Davila J, Swerdel MR, Moore JC, Cohen RI, Wu H, Sun YE, Hart RP. 2009. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One 4:e7192. doi:10.1371/journal.pone.0007192.
16. Jiang L, Lin C, Song L, Wu J, Chen B, Ying Z, Fang L, Yan X, He M, Li J, Li M. 2012. MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NFkappaB/ IkappaBalpha negative feedback loop. J. Clin. Invest. 122:33-47.
17. Kuchenbauer F, Mah SM, Heuser M, McPherson A, Ruschmann J, Rouhi A, Berg T, Bullinger L, Argiropoulos B, Morin RD, Lai D, Starczynowski DT, Karsan A, Eaves CJ, Watahiki A, Wang Y, Aparicio SA, Ganser A, Krauter J, Dohner H, Dohner K, Marra MA, Camargo FD, Palmqvist L, Buske C, Humphries RK. 2011. Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. Blood 118:3350 -3358.
18. Rayner KJ, Suarez Y, Davalos A, Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernandez-Hernando C. 2010. MiR-33 contributes to the regulation of cholesterol homeostasis. Science 328:1570-1573.
19. Najafi-Shoushtari SH, Kristo F, Li Y, Shioda T, Cohen DE, Gerszten RE, Naar AM. 2010. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328:1566 -1569.
20. Horton JD, Goldstein JL, Brown MS. 2002. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109:1125-1131.
21. Marquart TJ, Allen RM, Ory DS, Baldan A. 2010. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc. Natl. Acad. Sci. U. S. A. 107:12228 -12232.
22. Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, Nagao K, Kinoshita M, Kuwabara Y, Marusawa H, Iwanaga Y, Hasegawa K, Yokode M, Kimura T, Kita T. 2010. MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo. Proc. Natl. Acad. Sci. U. S. A. 107:17321-17326.
23. Davalos A, Goedeke L, Smibert P, Ramirez CM, Warrier NP, Andreo U, Cirera-Salinas D, Rayner K, Suresh U, Pastor-Pareja JC, Esplugues E, Fisher EA, Penalva LO, Moore KJ, Suarez Y, Lai EC, Fernandez-Hernando C. 2011. miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling. Proc. Natl. Acad. Sci. U. S. A. 108:9232-9237.
24. Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, Burant CF, Leclercq IA, MacDougald OA, Bommer GT. 2010. Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J. Biol. Chem. 285:33652-33661.
25. Ho PC, Chang KC, Chuang YS, Wei LN. 2011. Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production. FASEB J. 25:1758 -1766.
26. Chamorro-Jorganes A, Araldi E, Penalva LO, Sandhu D, Fernandez-Hernando C, Suarez Y. 2011. MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1. Arterioscler. Thromb. Vasc. Biol. 31:2595-2606.
27. Ramirez CM, Davalos A, Goedeke L, Salerno AG, Warrier N, Cirera-Salinas D, Suarez Y, Fernandez-Hernando C. 2011. MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1. Arterioscler. Thromb. Vasc. Biol. 31:2707-2714.
28. Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ. 2010. A Dicerindependent miRNA biogenesis pathway that requires Ago catalysis. Nature 465:584 -589.
29. Griffiths-Jones S, Hui JH, Marco A, Ronshaugen M. 2011. MicroRNA evolution by arm switching. EMBO Rep. 12:172-177.
30. Guo L, Lu Z. 2010. The fate of miRNA* strand through evolutionary analysis: implication for degradation as merely carrier strand or potential regulatory molecule? PLoS One 5:e11387. doi:10.1371/journal.pone .0011387.
31. Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC. 2010. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc. Natl. Acad. Sci. U. S. A. 107:15163-15168.
32. Dweep H, Sticht C, Pandey P, Gretz N. 2011. miRWalk-database: prediction of possiblemiRNAbinding sites by "walking" the genes of three genomes. J. Biomed. Inform. 44:839-847.
33. Huuskonen J, Fielding PE, Fielding CJ. 2004. Role of p160 coactivator complex in the activation of liver X receptor. Arterioscler. Thromb. Vasc. Biol. 24:703-708.
34. Brandt JM, Djouadi F, Kelly DP. 1998. Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 273: 23786-23792.
35. Chi SW, Zang JB, Mele A, Darnell RB. 2009. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-486.
36. Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jr, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T. 2010. Transcriptome-wideidentification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141:129 -141.
37. Nabeshima Y, Tazuma S, Kanno K, Hyogo H, Chayama K. 2009. Deletion of angiotensin II type I receptor reduces hepatic steatosis. J. Hepatol. 50:1226 -1235.
38. Voellenkle C, Rooij J, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F. 2012. Deepsequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. RNA 18:472-484.
39. Graff JW, Dickson AM, Clay G, McCaffrey AP, Wilson ME. 2012. Identifying functional microRNAs in macrophages with polarized phenotypes. J. Biol. Chem. 287:21816 -21825.
40. Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ. 2011. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature 478:404-407.
41. Rayner KJ, Sheedy FJ, Esau CC, Hussain FN, Temel RE, Parathath S, van Gils JM, Rayner AJ, Chang AN, Suarez Y, Fernandez-Hernando C, Fisher EA, Moore KJ. 2011. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J. Clin. Invest. 121:2921-2931.
42. Biasiolo M, Sales G, Lionetti M, Agnelli L, Todoerti K, Bisognin A, Coppe A, Romualdi C, Neri A, Bortoluzzi S. 2011. Impact of host genes and strand selection on miRNA and miRNA* expression. PLoS One 6:e23854. doi:10.1371/journal.pone.0023854.