메뉴 건너뛰기




Volumn 3, Issue 5, 2012, Pages 364-371

MiR-122 in hepatic function and liver diseases

Author keywords

hepatitis B virus (HBV); hepatitis C virus (HCV); hepatocellular carcinoma (HCC); lipid metabolism; liver development; miR 122

Indexed keywords

ANTAGOMIR; LOCKED NUCLEIC ACID; MICRORNA 122; MIRAVIRSEN; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; PEGINTERFERON ALPHA; VIRUS RNA;

EID: 84861705805     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-012-2036-3     Document Type: Review
Times cited : (166)

References (59)
  • 1
    • 70450285075 scopus 로고    scopus 로고
    • MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
    • Bai, S., Nasser, M. W., Wang, B., Hsu, S. H., Datta, J., Kutay, H., Yadav, A., Nuovo, G., Kumar, P., and Ghoshal, K. (2009). MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem 284, 32015-32027.
    • (2009) J Biol Chem , vol.284 , pp. 32015-32027
    • Bai, S.1    Nasser, M.W.2    Wang, B.3    Hsu, S.H.4    Datta, J.5    Kutay, H.6    Yadav, A.7    Nuovo, G.8    Kumar, P.9    Ghoshal, K.10
  • 2
    • 78650196925 scopus 로고    scopus 로고
    • MicroRNAs prevent the generation of autoreactive antibodies
    • Belver, L., de Yébenes, V. G., and Ramiro, A. R. (2010). MicroRNAs prevent the generation of autoreactive antibodies. Immunity 33, 713-722.
    • (2010) Immunity , vol.33 , pp. 713-722
    • Belver, L.1    de Yébenes, V.G.2    Ramiro, A.R.3
  • 4
    • 79955599925 scopus 로고    scopus 로고
    • CPEB and two poly^(A) polymerases control miR-122 stability and p53 mRNA translation
    • Burns, D. M., D'Ambrogio, A., Nottrott, S., and Richter, J. D. (2011). CPEB and two poly (A) polymerases control miR-122 stability and p53 mRNA translation. Nature 473, 105-108.
    • (2011) Nature , vol.473 , pp. 105-108
    • Burns, D.M.1    D'Ambrogio, A.2    Nottrott, S.3    Richter, J.D.4
  • 5
    • 67349115688 scopus 로고    scopus 로고
    • MicroRNAs: novel regulators of immunity
    • Carissimi, C., Fulci, V., and Macino, G. (2009). MicroRNAs: novel regulators of immunity. Autoimmun Rev 8, 520-524.
    • (2009) Autoimmun Rev , vol.8 , pp. 520-524
    • Carissimi, C.1    Fulci, V.2    Macino, G.3
  • 6
    • 49149121957 scopus 로고    scopus 로고
    • Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells
    • Chang, J., Guo, J. T., Jiang, D., Guo, H., Taylor, J. M., and Block, T. M. (2008). Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells. J Virol 82, 8215-8223.
    • (2008) J Virol , vol.82 , pp. 8215-8223
    • Chang, J.1    Guo, J.T.2    Jiang, D.3    Guo, H.4    Taylor, J.M.5    Block, T.M.6
  • 7
    • 40949106491 scopus 로고    scopus 로고
    • Construction and identification of a human liver specific microRNA eukaryotic expression vector
    • Chen, S., Ni, M., Yu, B., Lv, T., Lu, M., and Gong, F. (2007). Construction and identification of a human liver specific microRNA eukaryotic expression vector. Cell Mol Immunol 4, 473-477.
    • (2007) Cell Mol Immunol , vol.4 , pp. 473-477
    • Chen, S.1    Ni, M.2    Yu, B.3    Lv, T.4    Lu, M.5    Gong, F.6
  • 8
    • 82655181501 scopus 로고    scopus 로고
    • A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication
    • Chen, Y., Shen, A., Rider, P. J., Yu, Y., Wu, K., Mu, Y., Hao, Q., Liu, Y., Gong, H., Zhu, Y., et al. (2011). A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication. FASEB J 25, 4511-4521.
    • (2011) FASEB J , vol.25 , pp. 4511-4521
    • Chen, Y.1    Shen, A.2    Rider, P.J.3    Yu, Y.4    Wu, K.5    Mu, Y.6    Hao, Q.7    Liu, Y.8    Gong, H.9    Zhu, Y.10
  • 9
    • 70349976819 scopus 로고    scopus 로고
    • Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
    • Coulouarn, C., Factor, V. M., Andersen, J. B., Durkin, M. E., and Thorgeirsson, S. S. (2009). Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 28, 3526-3536.
    • (2009) Oncogene , vol.28 , pp. 3526-3536
    • Coulouarn, C.1    Factor, V.M.2    Andersen, J.B.3    Durkin, M.E.4    Thorgeirsson, S.S.5
  • 10
    • 70449729916 scopus 로고    scopus 로고
    • In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA
    • Díaz-Toledano, R., Ariza-Mateos, A., Birk, A., Martínez-García, B., and Gómez, J. (2009). In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA. Nucleic Acids Res 37, 5498-5510.
    • (2009) Nucleic Acids Res , vol.37 , pp. 5498-5510
    • Díaz-Toledano, R.1    Ariza-Mateos, A.2    Birk, A.3    Martínez-García, B.4    Gómez, J.5
  • 14
    • 37349113774 scopus 로고    scopus 로고
    • Inhibition of microRNA with antisense oligonucleotides
    • Esau, C. C. (2008). Inhibition of microRNA with antisense oligonucleotides. Methods 44, 55-60.
    • (2008) Methods , vol.44 , pp. 55-60
    • Esau, C.C.1
  • 15
    • 80053136743 scopus 로고    scopus 로고
    • miR-122 inhibits viral replication and cell proliferation in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3
    • Fan, C. G., Wang, C. M., Tian, C., Wang, Y., Li, L., Sun, W. S., Li, R. F., and Liu, Y. G. (2011). miR-122 inhibits viral replication and cell proliferation in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3. Oncol Rep 26, 1281-1286.
    • (2011) Oncol Rep , vol.26 , pp. 1281-1286
    • Fan, C.G.1    Wang, C.M.2    Tian, C.3    Wang, Y.4    Li, L.5    Sun, W.S.6    Li, R.F.7    Liu, Y.G.8
  • 16
    • 79952114916 scopus 로고    scopus 로고
    • The liver-specific microRNA miR-122: biology and therapeutic potential
    • Filipowicz, W., and Grosshans, H. (2011). The liver-specific microRNA miR-122: biology and therapeutic potential. Prog Drug Res 67, 221-238.
    • (2011) Prog Drug Res , vol.67 , pp. 221-238
    • Filipowicz, W.1    Grosshans, H.2
  • 17
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 21
    • 77953315225 scopus 로고    scopus 로고
    • Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122
    • Jangra, R. K., Yi, M., and Lemon, S. M. (2010). Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. J Virol 84, 6615-6625.
    • (2010) J Virol , vol.84 , pp. 6615-6625
    • Jangra, R.K.1    Yi, M.2    Lemon, S.M.3
  • 22
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • Jopling, C. L., Yi, M., Lancaster, A. M., Lemon, S. M., and Sarnow, P. (2005). Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309, 1577-1581.
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 23
    • 84877263372 scopus 로고    scopus 로고
    • Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance
    • 27 Dec 2011. doi: 10. 1002/mc. 21864
    • Karakatsanis A, Papaconstantinou I, Gazouli M, Lyberopoulou A, Polymeneas G, Voros D. (2011). Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR-146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance. Mol Carcinog 27 Dec 2011. doi: 10. 1002/mc. 21864.
    • (2011) Mol Carcinog
    • Karakatsanis, A.1    Papaconstantinou, I.2    Gazouli, M.3    Lyberopoulou, A.4    Polymeneas, G.5    Voros, D.6
  • 26
    • 36749086533 scopus 로고    scopus 로고
    • Association of HLA-DRB1*13 and TNF-alpha gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population
    • Kummee, P., Tangkijvanich, P., Poovorawan, Y., and Hirankarn, N. (2007). Association of HLA-DRB1*13 and TNF-alpha gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population. J Viral Hepat 14, 841-848.
    • (2007) J Viral Hepat , vol.14 , pp. 841-848
    • Kummee, P.1    Tangkijvanich, P.2    Poovorawan, Y.3    Hirankarn, N.4
  • 29
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B. P., Burge, C. B., and Bartel, D. P. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 30
    • 45549103746 scopus 로고    scopus 로고
    • microRNAs and the immune response
    • Lindsay, M. A. (2008). microRNAs and the immune response. Trends Immunol 29, 343-351.
    • (2008) Trends Immunol , vol.29 , pp. 343-351
    • Lindsay, M.A.1
  • 31
    • 79959836816 scopus 로고    scopus 로고
    • A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus
    • Luo, X., Yang, W., Ye, D. Q., Cui, H., Zhang, Y., Hirankarn, N., Qian, X., Tang, Y., Lau, Y. L., de Vries, N., et al. (2011). A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. PLoS Genet 7, e1002128.
    • (2011) PLoS Genet , vol.7
    • Luo, X.1    Yang, W.2    Ye, D.Q.3    Cui, H.4    Zhang, Y.5    Hirankarn, N.6    Qian, X.7    Tang, Y.8    Lau, Y.L.9    de Vries, N.10
  • 32
    • 77953717411 scopus 로고    scopus 로고
    • Expression of miR-122 mediated by adenoviral vector induces apoptosis and cell cycle arrest of cancer cells
    • Ma, L., Liu, J., Shen, J., Liu, L., Wu, J., Li, W., Luo, J., Chen, Q., and Qian, C. (2010). Expression of miR-122 mediated by adenoviral vector induces apoptosis and cell cycle arrest of cancer cells. Cancer Biol Therapy 9, 554-561.
    • (2010) Cancer Biol Therapy , vol.9 , pp. 554-561
    • Ma, L.1    Liu, J.2    Shen, J.3    Liu, L.4    Wu, J.5    Li, W.6    Luo, J.7    Chen, Q.8    Qian, C.9
  • 33
    • 67649373353 scopus 로고    scopus 로고
    • Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway
    • Miyoshi, K., Okada, T. N., Siomi, H., and Siomi, M. C. (2009). Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway. RNA 15, 1282-1291.
    • (2009) Rna , vol.15 , pp. 1282-1291
    • Miyoshi, K.1    Okada, T.N.2    Siomi, H.3    Siomi, M.C.4
  • 39
    • 77953032534 scopus 로고    scopus 로고
    • Emerging paradigms of regulated microRNA processing
    • Newman, M. A., and Hammond, S. M. (2010). Emerging paradigms of regulated microRNA processing. Genes Dev 24, 1086-1092.
    • (2010) Genes Dev , vol.24 , pp. 1086-1092
    • Newman, M.A.1    Hammond, S.M.2
  • 40
    • 72849125318 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms
    • Norman, K. L., and Sarnow, P. (2010). Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. J Virol 84, 666-670.
    • (2010) J Virol , vol.84 , pp. 666-670
    • Norman, K.L.1    Sarnow, P.2
  • 41
    • 84856940552 scopus 로고    scopus 로고
    • Structural map of a Pan PS, microRNA-122: Hepatitis C virus complex
    • Pang, P. S., Pham, E. A., Elazar, M., Patel, S. G., Eckart, M. R., and Glenn, J. S. (2012). Structural map of a Pan PS, microRNA-122: Hepatitis C virus complex. J Virol 86, 1250-1254.
    • (2012) J Virol , vol.86 , pp. 1250-1254
    • Pang, P.S.1    Pham, E.A.2    Elazar, M.3    Patel, S.G.4    Eckart, M.R.5    Glenn, J.S.6
  • 45
    • 84860197893 scopus 로고    scopus 로고
    • MiR-146a in Immunity and Disease
    • Rusca, N., and Monticelli, S. (2011). MiR-146a in Immunity and Disease. Mol Biol Int 2011, 437301.
    • (2011) Mol Biol Int , vol.2011 , pp. 437301
    • Rusca, N.1    Monticelli, S.2
  • 46
    • 84860400268 scopus 로고    scopus 로고
    • miR than meets the eye
    • Sage, J., Ventura, A., and Macino, G. (2011). miR than meets the eye. Genes Dev 25, 1663-1667.
    • (2011) Genes Dev , vol.25 , pp. 1663-1667
    • Sage, J.1    Ventura, A.2    Macino, G.3
  • 47
    • 58149333128 scopus 로고    scopus 로고
    • Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy
    • Sarasin-Filipowicz, M., Krol, J., Markiewicz, I., Heim, M. H., and Filipowicz, W. (2009). Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat Med 15, 31-33.
    • (2009) Nat Med , vol.15 , pp. 31-33
    • Sarasin-Filipowicz, M.1    Krol, J.2    Markiewicz, I.3    Heim, M.H.4    Filipowicz, W.5
  • 48
    • 34848878881 scopus 로고    scopus 로고
    • Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes
    • Shan, Y., Zheng, J., Lambrecht, R. W., and Bonkovsky, H. L. (2007). Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. Gastroenterology 133, 1166-1174.
    • (2007) Gastroenterology , vol.133 , pp. 1166-1174
    • Shan, Y.1    Zheng, J.2    Lambrecht, R.W.3    Bonkovsky, H.L.4
  • 52
    • 84863116887 scopus 로고    scopus 로고
    • Loss of MiR-122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G1 modulated P53 activity
    • 23 Feb 2012. doi: 10. 1002/hep. 24809
    • Wang S, Qiu L, Yan X, Jin W, Wang Y, Chen L, Wu E, Ye X, Gao GF, Wang F, Chen Y, Duan Z, Meng S. (2012). Loss of MiR-122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G1 modulated P53 activity. Hepatology 23 Feb 2012. doi: 10. 1002/hep. 24809.
    • (2012) Hepatology
    • Wang, S.1    Qiu, L.2    Yan, X.3    Jin, W.4    Wang, Y.5    Chen, L.6    Wu, E.7    Ye, X.8    Gao, G.F.9    Wang, F.10    Chen, Y.11    Duan, Z.12    Meng, S.13
  • 53
    • 77957954445 scopus 로고    scopus 로고
    • Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development
    • Xu, H., He, J. H., Xiao, Z. D., Zhang, Q. Q., Chen, Y. Q., Zhou, H., and Qu, L. H. (2010). Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology 52, 1431-1442.
    • (2010) Hepatology , vol.52 , pp. 1431-1442
    • Xu, H.1    He, J.H.2    Xiao, Z.D.3    Zhang, Q.Q.4    Chen, Y.Q.5    Zhou, H.6    Qu, L.H.7
  • 54
    • 84862777271 scopus 로고    scopus 로고
    • MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/beta-catenin pathway
    • 26 Jan 2012. doi: 10. 1111/j. 1478-3231. 2011. 02750. x
    • Xu, J., Zhu, X., et al. (2012). MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/beta-catenin pathway. Liver Int 26 Jan 2012. doi: 10. 1111/j. 1478-3231. 2011. 02750. x.
    • (2012) Liver Int
    • Xu, J.1    Zhu, X.2
  • 55
    • 80051688308 scopus 로고    scopus 로고
    • MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest
    • Xu, Y., Xia, F., Ma, L., Shan, J., Shen, J., Yang, Z., Liu, J., Cui, Y., Bian, X., Bie, P., et al. (2011). MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest. Cancer Lett 310, 160-169.
    • (2011) Cancer Lett , vol.310 , pp. 160-169
    • Xu, Y.1    Xia, F.2    Ma, L.3    Shan, J.4    Shen, J.5    Yang, Z.6    Liu, J.7    Cui, Y.8    Bian, X.9    Bie, P.10
  • 56
    • 79960057790 scopus 로고    scopus 로고
    • Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma
    • Yang, F., Zhang, L., Wang, F., Wang, Y., Huo, X. S., Yin, Y. X., Wang, Y. Q., Zhang, L., and Sun, S. H. (2011). Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma. Neoplasia 13, 590-600.
    • (2011) Neoplasia , vol.13 , pp. 590-600
    • Yang, F.1    Zhang, L.2    Wang, F.3    Wang, Y.4    Huo, X.S.5    Yin, Y.X.6    Wang, Y.Q.7    Zhang, L.8    Sun, S.H.9
  • 57
    • 78049506983 scopus 로고    scopus 로고
    • A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma
    • Zeng, C., Wang, R., Li, D., Lin, X. J., Wei, Q. K., Yuan, Y., Wang, Q., Chen, W., and Zhuang, S. M. (2010). A novel GSK-3 beta-C/EBP alpha-miR-122-insulin-like growth factor 1 receptor regulatory circuitry in human hepatocellular carcinoma. Hepatology 52, 1702-1712.
    • (2010) Hepatology , vol.52 , pp. 1702-1712
    • Zeng, C.1    Wang, R.2    Li, D.3    Lin, X.J.4    Wei, Q.K.5    Yuan, Y.6    Wang, Q.7    Chen, W.8    Zhuang, S.M.9
  • 58
    • 77954820848 scopus 로고    scopus 로고
    • Dicer ablation impairs prostate stem cell activity and causes prostate atrophy
    • Zhang, L., Zhang, B., Valdez, J. M., Wang, F., Ittmann, M., and Xin, L. (2010). Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells 28, 1260-1269.
    • (2010) Stem Cells , vol.28 , pp. 1260-1269
    • Zhang, L.1    Zhang, B.2    Valdez, J.M.3    Wang, F.4    Ittmann, M.5    Xin, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.