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Volumn 298, Issue 1, 2010, Pages

Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation

Author keywords

C myb; MicroRNA 150; Microrna 194; Rac 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; MICRORNA; MICRORNA 150; MICRORNA 194; RAC1 PROTEIN; UNCLASSIFIED DRUG;

EID: 73549111067     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00220.2009     Document Type: Article
Times cited : (207)

References (25)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 431: 350-355, 2004.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 50549095181 scopus 로고    scopus 로고
    • let-7 microRNAs in development, stem cells and cancer
    • Bussing I, Slack FJ, Grosshans H. let-7 microRNAs in development, stem cells and cancer. Trends Mol Med 14: 400-409, 2008.
    • (2008) Trends Mol Med , vol.14 , pp. 400-409
    • Bussing, I.1    Slack, F.J.2    Grosshans, H.3
  • 3
    • 34548162930 scopus 로고    scopus 로고
    • Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells
    • Cao Q, Mak KM, Lieber CS. Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells. J Hepatol 46: 124-133, 2007.
    • (2007) J Hepatol , vol.46 , pp. 124-133
    • Cao, Q.1    Mak, K.M.2    Lieber, C.S.3
  • 4
    • 33644857025 scopus 로고    scopus 로고
    • Gene regulation by microRNAs
    • Carthew RW. Gene regulation by microRNAs. Curr Opin Genet Dev 16: 203-208, 2006.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 203-208
    • Carthew, R.W.1
  • 5
    • 58149386462 scopus 로고    scopus 로고
    • Cheung O, Puri P, Eicken C, Contos MJ, Mirshahi F, Maher JW, Kellum JM, Min H, Luketic VA, Sanyal AJ. Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology 48: 1810-1820, 2008.
    • Cheung O, Puri P, Eicken C, Contos MJ, Mirshahi F, Maher JW, Kellum JM, Min H, Luketic VA, Sanyal AJ. Nonalcoholic steatohepatitis is associated with altered hepatic MicroRNA expression. Hepatology 48: 1810-1820, 2008.
  • 7
    • 0034813009 scopus 로고    scopus 로고
    • Transcriptional regulation in hepatic stellate cells
    • Eng FJ, Friedman SL. Transcriptional regulation in hepatic stellate cells. Semin Liver Dis 21: 385-395, 2001.
    • (2001) Semin Liver Dis , vol.21 , pp. 385-395
    • Eng, F.J.1    Friedman, S.L.2
  • 8
    • 0032795312 scopus 로고    scopus 로고
    • Stress, superoxide, and signal transduction
    • Goldschmidt-Clermont PJ, Moldovan L. Stress, superoxide, and signal transduction. Gene Expr 7: 255-260, 1999.
    • (1999) Gene Expr , vol.7 , pp. 255-260
    • Goldschmidt-Clermont, P.J.1    Moldovan, L.2
  • 12
    • 59849084351 scopus 로고    scopus 로고
    • Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation
    • Ji J, Zhang J, Huang G, Qian J, Wang X, Mei S. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett 583: 759-766, 2009.
    • (2009) FEBS Lett , vol.583 , pp. 759-766
    • Ji, J.1    Zhang, J.2    Huang, G.3    Qian, J.4    Wang, X.5    Mei, S.6
  • 13
    • 56149119778 scopus 로고    scopus 로고
    • Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism
    • Jiang JX, Mikami K, Shah VH, Torok NJ. Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism. Hepatology 48: 1497-1505, 2008.
    • (2008) Hepatology , vol.48 , pp. 1497-1505
    • Jiang, J.X.1    Mikami, K.2    Shah, V.H.3    Torok, N.J.4
  • 15
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression
    • Lee KS, Buck M, Houglum K, Chojkier M. Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression. J Clin Invest 96: 2461-2468, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2461-2468
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 16
    • 52449090510 scopus 로고    scopus 로고
    • c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development
    • Lin YC, Kuo MW, Yu J, Kuo HH, Lin RJ, Lo WL, Yu AL. c-Myb is an evolutionary conserved miR-150 target and miR-150/c-Myb interaction is important for embryonic development. Mol Biol Evol 25: 2189-2198, 2008.
    • (2008) Mol Biol Evol , vol.25 , pp. 2189-2198
    • Lin, Y.C.1    Kuo, M.W.2    Yu, J.3    Kuo, H.H.4    Lin, R.J.5    Lo, W.L.6    Yu, A.L.7
  • 18
    • 60449093031 scopus 로고    scopus 로고
    • MicroRNAs make inroads into liver development
    • Rogler CE. MicroRNAs make inroads into liver development. Gastroenterology 136: 770-772, 2009.
    • (2009) Gastroenterology , vol.136 , pp. 770-772
    • Rogler, C.E.1
  • 22
    • 46949109527 scopus 로고    scopus 로고
    • Recent advances in the pathogenesis and diagnosis of liver fibrosis
    • Torok NJ. Recent advances in the pathogenesis and diagnosis of liver fibrosis. J Gastroenterol 43: 315-321, 2008.
    • (2008) J Gastroenterol , vol.43 , pp. 315-321
    • Torok, N.J.1
  • 25
    • 0032738763 scopus 로고    scopus 로고
    • Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis
    • Zhu J, Wu J, Frizell E, Liu SL, Bashey R, Rubin R, Norton P, Zern MA. Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology 117: 1198-1204, 1999.
    • (1999) Gastroenterology , vol.117 , pp. 1198-1204
    • Zhu, J.1    Wu, J.2    Frizell, E.3    Liu, S.L.4    Bashey, R.5    Rubin, R.6    Norton, P.7    Zern, M.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.