-
1
-
-
79952444246
-
Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association
-
Heidenreich, P.A. et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation 123, 933-944 (2011).
-
(2011)
Circulation
, vol.123
, pp. 933-944
-
-
Heidenreich, P.A.1
-
2
-
-
3142729178
-
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
-
Grundy, S.M. et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110, 227-239 (2004).
-
(2004)
Circulation
, vol.110
, pp. 227-239
-
-
Grundy, S.M.1
-
3
-
-
65249154191
-
Clock genes, intestinal transport and plasma lipid homeostasis
-
Hussain, M.M. & Pan, X. Clock genes, intestinal transport and plasma lipid homeostasis. Trends Endocrinol. Metab. 20, 177-185 (2009).
-
(2009)
Trends Endocrinol. Metab.
, vol.20
, pp. 177-185
-
-
Hussain, M.M.1
Pan, X.2
-
4
-
-
20544476998
-
Intestinal lipoprotein assembly
-
Hussain, M.M., Fatma, S., Pan, X. & Iqbal, J. Intestinal lipoprotein assembly. Curr. Opin. Lipidol. 16, 281-285 (2005).
-
(2005)
Curr. Opin. Lipidol.
, vol.16
, pp. 281-285
-
-
Hussain, M.M.1
Fatma, S.2
Pan, X.3
Iqbal, J.4
-
5
-
-
43249096797
-
Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism
-
Hussain, M.M. et al. Microsomal triglyceride transfer protein in plasma and cellular lipid metabolism. Curr. Opin. Lipidol. 19, 277-284 (2008).
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 277-284
-
-
Hussain, M.M.1
-
6
-
-
0037244002
-
Microsomal triglyceride transfer protein and its role in apolipoprotein B-lipoprotein assembly
-
Hussain, M.M., Shi, J. & Dreizen, P. Microsomal triglyceride transfer protein and its role in apolipoprotein B-lipoprotein assembly. J. Lipid Res. 44, 22-32 (2003).
-
(2003)
J. Lipid Res.
, vol.44
, pp. 22-32
-
-
Hussain, M.M.1
Shi, J.2
Dreizen, P.3
-
7
-
-
84857133310
-
Multiple functions of microsomal triglyceride transfer protein
-
Hussain, M.M., Rava, P., Walsh, M., Rana, M. & Iqbal, J. Multiple functions of microsomal triglyceride transfer protein. Nutr. Metab. (Lond) 9, 14 (2012).
-
(2012)
Nutr. Metab. (Lond)
, vol.9
, pp. 14
-
-
Hussain, M.M.1
Rava, P.2
Walsh, M.3
Rana, M.4
Iqbal, J.5
-
8
-
-
0033826953
-
The role of the microsomal triglygeride transfer protein in abetalipoproteinemia
-
Berriot-Varoqueaux, N., Aggerbeck, L.P., Samson-Bouma, M. & Wetterau, J.R. The role of the microsomal triglygeride transfer protein in abetalipoproteinemia. Annu. Rev. Nutr. 20, 663-697 (2000).
-
(2000)
Annu. Rev. Nutr.
, vol.20
, pp. 663-697
-
-
Berriot-Varoqueaux, N.1
Aggerbeck, L.P.2
Samson-Bouma, M.3
Wetterau, J.R.4
-
9
-
-
33846671059
-
MTP inhibition as a treatment for dyslipidaemias: Time to deliver or empty promises?
-
Burnett, J.R. & Watts, G.F. MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises? Expert Opin. Ther. Targets 11, 181-189 (2007).
-
(2007)
Expert Opin. Ther. Targets
, vol.11
, pp. 181-189
-
-
Burnett, J.R.1
Watts, G.F.2
-
10
-
-
56549091924
-
New approaches to target microsomal triglyceride transfer protein
-
Hussain, M.M. & Bakillah, A. New approaches to target microsomal triglyceride transfer protein. Curr. Opin. Lipidol. 19, 572-578 (2008).
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 572-578
-
-
Hussain, M.M.1
Bakillah, A.2
-
11
-
-
33846151732
-
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
-
Cuchel, M. et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N. Engl. J. Med. 356, 148-156 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 148-156
-
-
Cuchel, M.1
-
12
-
-
48349088178
-
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
-
Samaha, F.F., McKenney, J., Bloedon, L.T., Sasiela, W.J. & Rader, D.J. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat. Clin. Pract. Cardiovasc. Med. 5, 497-505 (2008).
-
(2008)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.5
, pp. 497-505
-
-
Samaha, F.F.1
McKenney, J.2
Bloedon, L.T.3
Sasiela, W.J.4
Rader, D.J.5
-
13
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
14
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
15
-
-
81355123438
-
Evolution of microRNA diversity and regulation in animals
-
Berezikov, E. Evolution of microRNA diversity and regulation in animals. Nat. Rev. Genet. 12, 846-860 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 846-860
-
-
Berezikov, E.1
-
16
-
-
24344490760
-
Determining hepatic triglyceride production in mice: Comparison of poloxamer 407 with Triton WR-1339
-
Millar, J.S., Cromley, D.A., McCoy, M.G., Rader, D.J. & Billheimer, J.T. Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339. J. Lipid Res. 46, 2023-2028 (2005).
-
(2005)
J. Lipid Res.
, vol.46
, pp. 2023-2028
-
-
Millar, J.S.1
Cromley, D.A.2
McCoy, M.G.3
Rader, D.J.4
Billheimer, J.T.5
-
17
-
-
79959845414
-
MicroRNAs 103 and 107 regulate insulin sensitivity
-
Trajkovski, M. et al. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474, 649-653 (2011).
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
-
18
-
-
84873294316
-
MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia
-
Vickers, K.C. et al. MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia. Hepatology 57, 533-542 (2013).
-
(2013)
Hepatology
, vol.57
, pp. 533-542
-
-
Vickers, K.C.1
-
19
-
-
77953787211
-
MiR-33 contributes to the regulation of cholesterol homeostasis
-
Rayner, K.J. et al. MiR-33 contributes to the regulation of cholesterol homeostasis. Science 328, 1570-1573 (2010).
-
(2010)
Science
, vol.328
, pp. 1570-1573
-
-
Rayner, K.J.1
-
20
-
-
77953780835
-
MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
-
Najafi-Shoushtari, S.H. et al. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science 328, 1566-1569 (2010).
-
(2010)
Science
, vol.328
, pp. 1566-1569
-
-
Najafi-Shoushtari, S.H.1
-
21
-
-
77955456415
-
MiR-33 links SREBP-2 induction to repression of sterol transporters
-
Marquart, T.J., Allen, R.M., Ory, D.S. & Baldan, A. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc. Natl. Acad. Sci. USA 107, 12228-12232 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12228-12232
-
-
Marquart, T.J.1
Allen, R.M.2
Ory, D.S.3
Baldan, A.4
-
22
-
-
0031657558
-
Resistance of chylomicron and VLDL remnants to post-heparin lipolysis in ApoE-deficient mice: The role of apoE in lipoprotein lipase-mediated lipolysis in vivo and in vitro
-
Zsigmond, E., Fuke, Y., Li, L., Kobayashi, K. & Chan, L. Resistance of chylomicron and VLDL remnants to post-heparin lipolysis in ApoE-deficient mice: the role of apoE in lipoprotein lipase-mediated lipolysis in vivo and in vitro. J. Lipid Res. 39, 1852-1861 (1998).
-
(1998)
J. Lipid Res.
, vol.39
, pp. 1852-1861
-
-
Zsigmond, E.1
Fuke, Y.2
Li, L.3
Kobayashi, K.4
Chan, L.5
-
23
-
-
33744828960
-
Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL
-
Westerterp, M., de Haan, W., Berbee, J.F., Havekes, L.M. & Rensen, P.C. Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL. J. Lipid Res. 47, 1203-1211 (2006).
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1203-1211
-
-
Westerterp, M.1
De Haan, W.2
Berbee, J.F.3
Havekes, L.M.4
Rensen, P.C.5
-
24
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
Lagos-Quintana, M., Rauhut, R., Lendeckel, W. & Tuschl, T. Identification of novel genes coding for small expressed RNAs. Science 294, 853-858 (2001).
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
25
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana, M. et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735-739 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
-
26
-
-
70450203075
-
The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1
-
Agrawal, R., Tran, U. & Wessely, O. The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development 136, 3927-3936 (2009).
-
(2009)
Development
, vol.136
, pp. 3927-3936
-
-
Agrawal, R.1
Tran, U.2
Wessely, O.3
-
27
-
-
77954954098
-
Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells
-
Yu, F. et al. Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells. Oncogene 29, 4194-4204 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 4194-4204
-
-
Yu, F.1
-
28
-
-
79960565215
-
Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis
-
Zaragosi, L.E. et al. Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis. Genome Biol. 12, R64 (2011).
-
(2011)
Genome Biol.
, vol.12
, Issue.R64
-
-
Zaragosi, L.E.1
-
29
-
-
85046981444
-
MicroRNA-30c promotes human adipocyte differentiation and co-represses PAI-1 and ALK2
-
Karbiener, M. et al. MicroRNA-30c promotes human adipocyte differentiation and co-represses PAI-1 and ALK2. RNA Biol. 8, 850-860 (2011).
-
(2011)
RNA Biol.
, vol.8
, pp. 850-860
-
-
Karbiener, M.1
-
30
-
-
0033525712
-
Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein low density lipoprotein production in a viable conditional knockout mouse
-
Chang, B.H.J. et al. Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein low density lipoprotein production in a viable conditional knockout mouse. J. Biol. Chem. 274, 6051-6055 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 6051-6055
-
-
Chang, B.H.J.1
-
31
-
-
84862789317
-
Phospholipid transfer activity of MTP promotes assembly of phospholipid-rich apoB-containing lipoproteins and reduces plasma as well as hepatic lipids in mice
-
Khatun, I. et al. Phospholipid transfer activity of MTP promotes assembly of phospholipid-rich apoB-containing lipoproteins and reduces plasma as well as hepatic lipids in mice. Hepatology 55, 1356-1368 (2012).
-
(2012)
Hepatology
, vol.55
, pp. 1356-1368
-
-
Khatun, I.1
-
32
-
-
0042357173
-
Multiple independently regulated pathways of cholesterol transport across the intestinal epithelial cells
-
Iqbal, J., Anwar, K. & Hussain, M.M. Multiple, independently regulated pathways of cholesterol transport across the intestinal epithelial cells. J. Biol. Chem. 278, 31610-31620 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31610-31620
-
-
Iqbal, J.1
Anwar, K.2
Hussain, M.M.3
-
33
-
-
0033578604
-
Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
-
Ibrahimi, A. et al. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J. Biol. Chem. 274, 26761-26766 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26761-26766
-
-
Ibrahimi, A.1
-
34
-
-
0029878959
-
Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteins
-
Wu, X., Zhou, M.Y., Huang, L.S., Wetterau, J. & Ginsberg, H.N. Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteins. J. Biol. Chem. 271, 10277-10281 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10277-10281
-
-
Wu, X.1
Zhou, M.Y.2
Huang, L.S.3
Wetterau, J.4
Ginsberg, H.N.5
-
35
-
-
1642506210
-
A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein
-
Athar, H., Iqbal, J., Jiang, X.C. & Hussain, M.M. A simple, rapid, and sensitive fluorescence assay for microsomal triglyceride transfer protein. J. Lipid Res. 45, 764-772 (2004).
-
(2004)
J. Lipid Res.
, vol.45
, pp. 764-772
-
-
Athar, H.1
Iqbal, J.2
Jiang, X.C.3
Hussain, M.M.4
-
36
-
-
23244441822
-
Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein
-
Rava, P., Athar, H., Johnson, C. & Hussain, M.M. Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein. J. Lipid Res. 46, 1779-1785 (2005).
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1779-1785
-
-
Rava, P.1
Athar, H.2
Johnson, C.3
Hussain, M.M.4
-
37
-
-
16044364083
-
An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells
-
Jamil, H. et al. An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells. Proc. Natl. Acad. Sci. USA 93, 11991-11995 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11991-11995
-
-
Jamil, H.1
-
38
-
-
0038143355
-
A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B: Implications for human and insect lipid transport and metabolism
-
Sellers, J.A., Hou, L., Athar, H., Hussain, M.M. & Shelness, G.S. A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B: implications for human and insect lipid transport and metabolism. J. Biol. Chem. 278, 20367-20373 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 20367-20373
-
-
Sellers, J.A.1
Hou, L.2
Athar, H.3
Hussain, M.M.4
Shelness, G.S.5
-
39
-
-
77649100083
-
NR2F1 and IRE1-ß suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells
-
Dai, K., Khatun, I. & Hussain, M.M. NR2F1 and IRE1-ß suppress microsomal triglyceride transfer protein expression and lipoprotein assembly in undifferentiated intestinal epithelial cells. Arterioscler. Thromb. Vasc. Biol. 30, 568-574 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 568-574
-
-
Dai, K.1
Khatun, I.2
Hussain, M.M.3
-
40
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch, J., Lees, M. & Sloane Stanley, G.H. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509 (1957).
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
41
-
-
0017177024
-
Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats
-
Stansbie, D., Brownsey, R.W., Crettaz, M. & Denton, R.M. Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. Biochem. J. 160, 413-416 (1976).
-
(1976)
Biochem. J.
, vol.160
, pp. 413-416
-
-
Stansbie, D.1
Brownsey, R.W.2
Crettaz, M.3
Denton, R.M.4
-
42
-
-
0017172855
-
Dietary control of triglyceride and phospholipid synthesis in rat liver slices
-
Iritani, N., Yamashita, S. & Numa, S. Dietary control of triglyceride and phospholipid synthesis in rat liver slices. J. Biochem. 80, 217-222 (1976).
-
(1976)
J. Biochem.
, vol.80
, pp. 217-222
-
-
Iritani, N.1
Yamashita, S.2
Numa, S.3
-
43
-
-
84862271804
-
Increased intestinal lipid absorption caused by Ire1ß deficiency contributes to hyperlipidemia and atherosclerosis in apolipoprotein E-deficient mice
-
Iqbal, J. et al. Increased intestinal lipid absorption caused by Ire1ß deficiency contributes to hyperlipidemia and atherosclerosis in apolipoprotein E-deficient mice. Circ. Res. 110, 1575-1584 (2012).
-
(2012)
Circ. Res.
, vol.110
, pp. 1575-1584
-
-
Iqbal, J.1
|