Loss of expression of miR-335 is implicated in hepatic stellate cell migration and activation

Experimental Cell Research

Volumn 317, Issue 12, 2011, Pages 1714-1725

  Chen, Chao ^a   Wu, Chao Qun ^b   Zhang, Zong Qi ^c   Yao, Ding Kang ^a   Zhu, Liang ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Activation; Gene ontology; Hepatic stellate cells; Migration; MiR 335; TNC

Indexed keywords

COLLAGEN TYPE 1; GLYCOPROTEIN; MICRORNA; MICRORNA 335; TENASCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STELLATE CELL;

EID: 79958845153     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.05.001     Document Type: Article

References (17)

1. Torok N.J. Recent advances in the pathogenesis and diagnosis of liver fibrosis. J. Gastroenterol. 2008, 43(5):315-321.
2. Horn T., Junge J., Christoffersen P. Early alcoholic liver injury. Activation of lipocytes in acinar zone 3 and correlation to degree of collagen formation in the Disse space. J. Hepatol. 1986, 3:333-340.
3. Chitwood D.H., Timmermans M.C. Target mimics modulate miRNAs. Nat. Genet. 2007, 39:935-936.
4. Guo C.J., Pan Q., Li D.G., Sun H., Liu B.W. miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: an essential role for apoptosis. J. Hepatol. Apr 2009, 50(4):766-778.
5. Guo C.J., Pan Q., Jiang B., Chen G.Y., Li D.G. Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells. Apoptosis Nov 2009, 14(11):1331-1340.
6. Ji J., Zhang J., Huang G., Qian J., Wang X., Mei S. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation. FEBS Lett. Feb 18 2009, 583(4):759-766.
7. Venugopal S.K., Jiang J., Kim T.H., Li Y., Wang S.S., Torok N.J., Wu J., Zern M.A. Liver fibrosis causes downregulation of miRNA150 and miRNA194 in hepatic stellate cells, and their overexpression causes decreased stellate cellactivation. Am. J. Physiol. Gastrointest. Liver Physiol. Jan 2010, 298(1):G101-G106.
8. Ogawa T., Iizuka M., Sekiya Y., Yoshizato K., Ikeda K., Kawada N. Suppression of type I collagen production by microRNA-29b in cultured human stellate cells. Biochem. Biophys. Res. Commun. Jan 1 2010, 391(1):316-321.
9. Roderburg C., Urban G.W., Bettermann K., Vucur M., Zimmermann H., Schmidt S., Janssen J., Koppe C., Knolle P., Castoldi M., Tacke F., Trautwein C., Luedde T. Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology Aug 20 2010.
10. Friedman S.L., Roll F.J. Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan. Anal. Biochem. Feb 15 1987, 161(1):207-218.
11. Yu A.C., Lee Y.L., Eng L.F. Astrogliosis in culture: I. The model and the effect of antisense oligonucleotides on glial fibrillary acidic protein synthesis. J. Neurosci. Res. Feb 15 1993, 34(3):295-303.
12. Kinnman N., Hultcrantz R., Barbu V., Rey C., Wendum D., Poupon R., Housset C. PDGF-mediated chemoattraction of hepatic stellate ceils by bile duct segments in cholestatic liver injury. Lab. Invest. May 2000, 80(5):697-707.
13. Ikeda K., Wakahara T., Wang Y.Q., Kadoya H., Kawada N., Kaneda K. In vitro migratory potential of rat quiescent hepatic stellate cells and its augmentation by cell activation. Hepatology Jun 1999, 29(6):1760-1767.
14. Failli P., DeFRANCO R.M., Caligiuri A., Gentilini A., Romanelli R.G., Marra F., Batignani G., Guerra C.T., Laffi G., Gentilini P., Pinzani M. Nitrovasodilators inhibit platelet-derived growth factor-induced proliferation and migration of activated human hepatic stellate cells. Gastroenterology Aug 2000, 119(2):479-492.
15. Yang C., Zeisberg M., Mosterman B., Sudhakar A., Yerramalla U., Holthaus K., Xu L., Eng F., Afdhal N., Kalluri R. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology Jan 2003, 124(1):147-159.
16. Carloni V., Romanelli R.G., Pinzani M., Laffi G., Gentilini P. Focal adhesion kinase and phospholipase C gamma involvement in adhesion and migration of human hepatic stellate cells. Gastroenterology Feb 1997, 112(2):522-531.
17. Tangkijvanich P., Melton A.C., Santiskulvong C., Yee H.F. Rho and p38 MAP kinase signaling pathways mediate LPA-stimulated hepatic myofibroblast. J. Biomed. Sci. May-Jun 2003, 10(3):352-358.