Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Zhang, Xiaonan ^a   Zhang, Zhanqing ^b   Dai, Fahui ^a   Shi, Bisheng ^a   Chen, Liang ^b   Zhang, Xinxin ^c   Zang, Guoqing ^c   Zhang, Jiming ^d   Chen, Xiaorong ^e   Qian, Fangxing ^f   Hu, Yunwen ^a   Yuan, Zhenghong ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d FUDAN UNIVERSITY   (China)

^e SHANGHAI PUBLIC HEALTH CLINICAL CENTER   (China)

^f Shanghai Changning Center Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; APOLIPOPROTEIN A2; BILIRUBIN; BIOLOGICAL MARKER; CYTOCHROME P450 2E1; GAMMA GLUTAMYLTRANSFERASE; HAPTOGLOBIN; HEPATITIS B SURFACE ANTIGEN; MESSENGER RNA; MICRORNA; MICRORNA 122; ALANINE AMINOTRANSFERASE; APOA2 PROTEIN, HUMAN; HP PROTEIN, HUMAN; MIRN122 MICRORNA, HUMAN; SERUM ALBUMIN;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHRONIC LIVER DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOPRECIPITATION; LIVER CELL; MAJOR CLINICAL STUDY; MALE; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; TISSUE SPECIFICITY; VIRUS CARRIER; VIRUS LOAD; AGED; BLOOD; CASE CONTROL STUDY; DIFFERENTIAL DIAGNOSIS; GENE EXPRESSION; GENETICS; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HETEROZYGOTE; METABOLISM; MIDDLE AGED;

ADULT; AGED; ALANINE TRANSAMINASE; APOLIPOPROTEIN A-II; BIOLOGICAL MARKERS; CARRIER STATE; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP2E1; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENE EXPRESSION; HAPTOGLOBINS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; MALE; MICRORNAS; MIDDLE AGED; RNA, MESSENGER; SERUM ALBUMIN;

EID: 84898605517     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092112     Document Type: Article

References (18)

1. Pinzani P, Salvianti F, Pazzagli M, Orlando C (2010) Circulating nucleic acids in cancer and pregnancy. Methods 50: 302-307.
2. Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, et al. (2009) Circulating microRNAs, potential biomarkers for drug-induced liver injury. Proc Natl Acad Sci U S A 106: 4402-4407.
3. Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, et al. (2012) Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology 56: 1946- 1957.
4. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 105: 10513-10518.
5. Zhou J, Yu L, Gao X, Hu J, Wang J, et al. (2011) Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol 29: 4781-4788.
6. Miyamoto M, Yanai M, Ookubo S, Awasaki N, Takami K, et al. (2008) Detection of Cell-Free, Liver-Specific mRNAs in Peripheral Blood from Rats with Hepatotoxicity: A Potential Toxicological Biomarker for Safety Evaluation. Toxicological Sciences 106: 538-545.
7. Wetmore BA, Brees DJ, Singh R, Watkins PB, Andersen ME, et al. (2010) Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury. Hepatology 51: 2127-2139.
8. Chan RWY, Wong J, Chan HLY, Mok TSK, Lo WYW, et al. (2009) Aberrant Concentrations of Liver-Derived Plasma Albumin mRNA in Liver Pathologies. Clinical Chemistry 56: 82-89.
9. Arataki K, Hayes CN, Akamatsu S, Akiyama R, Abe H, et al. (2013) Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B. J Med Virol 85: 789-798.
10. Li LM, Hu ZB, Zhou ZX, Chen X, Liu FY, et al. (2010) Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBVpositive hepatocarcinoma. Cancer Res 70: 9798-9807.
11. Novellino L, Rossi RL, Bonino F, Cavallone D, Abrignani S, et al. (2012) Circulating hepatitis B surface antigen particles carry hepatocellular micro- RNAs. PLoS One 7: e31952.
12. Gilad S, Meiri E, Yogev Y, Benjamin S, Lebanony D, et al. (2008) Serum microRNAs are promising novel biomarkers. PLoS One 3: e3148.
13. Chen X, Ba Y, Ma L, Cai X, Yin Y, et al. (2008) Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18: 997-1006.
14. McDonald JS, Milosevic D, Reddi HV, Grebe SK, Algeciras-Schimnich A (2011) Analysis of Circulating MicroRNA: Preanalytical and Analytical Challenges. Clinical Chemistry 57: 833-840.
15. Pritchard CC, Kroh E, Wood B, Arroyo JD, Dougherty KJ, et al. (2012) Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev Res (Phila) 5: 492-497.
16. Cheng HH, Yi HS, Kim Y, Kroh EM, Chien JW, et al. (2013) Plasma processing conditions substantially influence circulating microRNA biomarker levels. PLoS One 8: e64795.
17. Cheng HH, Yi HS, Kim Y, Kroh EM, Chien JW, et al. (2013) Plasma processing conditions substantially influence circulating microRNA biomarker levels. PLoS One 8: e64795. (Pubitemid 38435550)
18. Li Y (2006) Serum Circulating Human mRNA Profiling and Its Utility for Oral Cancer Detection. Journal of Clinical Oncology 24: 1754-1760. (Pubitemid 46622147)