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Volumn , Issue , 2014, Pages 127-180

Taxol, Taxoids, and Related Taxanes

Author keywords

Anticancer; Antitubercular agents; Cancer; Taxanes; Taxoid; Taxol

Indexed keywords


EID: 84926483780     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527676545.ch04     Document Type: Chapter
Times cited : (10)

References (318)
  • 1
    • 7144248725 scopus 로고
    • Plant antitumor agents: I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
    • Wall, M.E., Wani, M.C., Cook, C.E., Palmer, C.E., and McPhail, A.T. (1966) Plant antitumor agents: I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. Journal of the American Chemical Society, 88, 3888-3894.
    • (1966) Journal of the American Chemical Society , vol.88 , pp. 3888-3894
    • Wall, M.E.1    Wani, M.C.2    Cook, C.E.3    Palmer, C.E.4    McPhail, A.T.5
  • 2
    • 0015211527 scopus 로고
    • Plant antitumor agents: VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani, M.C., Taylor, H.L., Wall, M.E., Coggan, P., and McPhail, A.T. (1971) Plant antitumor agents: VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of the American Chemical Society, 93, 2325-2327.
    • (1971) Journal of the American Chemical Society , vol.93 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggan, P.4    McPhail, A.T.5
  • 4
    • 0017105425 scopus 로고
    • Isolation and chemical characterization of antitumor agents from plants
    • Wall, M.E., Wani, M.C., and Taylor, H.L. (1976) Isolation and chemical characterization of antitumor agents from plants. Cancer Treatment Reports, 60, 1011-1014.
    • (1976) Cancer Treatment Reports , vol.60 , pp. 1011-1014
    • Wall, M.E.1    Wani, M.C.2    Taylor, H.L.3
  • 5
    • 0031754884 scopus 로고    scopus 로고
    • Tour de paclitaxel: biocatalysis for semisynthesis
    • Patel, R.N. (1998) Tour de paclitaxel: biocatalysis for semisynthesis. Annual Review of Microbiology, 98, 361-395.
    • (1998) Annual Review of Microbiology , vol.98 , pp. 361-395
    • Patel, R.N.1
  • 6
    • 0018188876 scopus 로고
    • Cytologic evidence that taxol, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison
    • Fuchs, D.A. and Johnson, R.K. (1978) Cytologic evidence that taxol, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison. Cancer Treatment Reports, 62, 1219-1222.
    • (1978) Cancer Treatment Reports , vol.62 , pp. 1219-1222
    • Fuchs, D.A.1    Johnson, R.K.2
  • 7
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Horwitz, S.B., Fant, J., and Schiff, P.B. (1979) Promotion of microtubule assembly in vitro by taxol. Nature, 277, 665-667.
    • (1979) Nature , vol.277 , pp. 665-667
    • Horwitz, S.B.1    Fant, J.2    Schiff, P.B.3
  • 8
    • 1442285598 scopus 로고    scopus 로고
    • Personal recollections on the early development of taxol
    • Horwitz, S.B. (2004) Personal recollections on the early development of taxol. Journal of Natural Products, 67, 136-138.
    • (2004) Journal of Natural Products , vol.67 , pp. 136-138
    • Horwitz, S.B.1
  • 9
    • 0025742954 scopus 로고
    • Government moves to increase taxol supply
    • Blume, E. (1991) Government moves to increase taxol supply. Journal of the National Cancer Institute, 83, 1054-1056.
    • (1991) Journal of the National Cancer Institute , vol.83 , pp. 1054-1056
    • Blume, E.1
  • 10
    • 0027430002 scopus 로고
    • The taxol supply crisis: new NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents
    • Cragg, G.M., Schepartz, S.A., Suffness, M., and Grever, M.R. (1993) The taxol supply crisis: new NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents. Journal of Natural Products, 56, 1657-1668.
    • (1993) Journal of Natural Products , vol.56 , pp. 1657-1668
    • Cragg, G.M.1    Schepartz, S.A.2    Suffness, M.3    Grever, M.R.4
  • 13
    • 0026723301 scopus 로고
    • Taxol: the first of the taxanes, an important new class of anti-cancer agents
    • Rowinsky, E.K., Onetto, N., Canetta, R.M., and Arbuck, S.G. (1992) Taxol: the first of the taxanes, an important new class of anti-cancer agents. Seminars in Oncology, 19, 646-662.
    • (1992) Seminars in Oncology , vol.19 , pp. 646-662
    • Rowinsky, E.K.1    Onetto, N.2    Canetta, R.M.3    Arbuck, S.G.4
  • 14
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of anti-microtubule chemotherapy agents
    • Rowinsky, E.K. (1997) The development and clinical utility of the taxane class of anti-microtubule chemotherapy agents. Annual Review of Medicine, 48, 353-374.
    • (1997) Annual Review of Medicine , vol.48 , pp. 353-374
    • Rowinsky, E.K.1
  • 17
    • 0034789998 scopus 로고    scopus 로고
    • Taxol: biosynthesis, molecular genetics and biotechnological applications
    • Jennewein, S. and Croteau, R. (2001) Taxol: biosynthesis, molecular genetics and biotechnological applications. Applied Microbiology and Biotechnology, 57, 13-19.
    • (2001) Applied Microbiology and Biotechnology , vol.57 , pp. 13-19
    • Jennewein, S.1    Croteau, R.2
  • 18
    • 0034680578 scopus 로고    scopus 로고
    • Studies on the biosynthesis of taxol: synthesis of taxa-4(20),11(12)-diene-2a, 5a-diol
    • Vazquez, A. and Williams, R.M. (2000) Studies on the biosynthesis of taxol: synthesis of taxa-4(20),11(12)-diene-2a, 5a-diol. The Journal of Organic Chemistry, 65, 7865-7869.
    • (2000) The Journal of Organic Chemistry , vol.65 , pp. 7865-7869
    • Vazquez, A.1    Williams, R.M.2
  • 20
    • 11944265206 scopus 로고
    • Search and discovery of new antitumour compounds
    • Potier, P. (1992) Search and discovery of new antitumour compounds. Chemical Society Reviews, 21, 113-119.
    • (1992) Chemical Society Reviews , vol.21 , pp. 113-119
    • Potier, P.1
  • 22
    • 0000715988 scopus 로고
    • Taxanes from Taxus yunnanensis
    • Zhang, Z. and Jia, Z. (1990) Taxanes from Taxus yunnanensis. Phytochemistry, 29, 3673-3675.
    • (1990) Phytochemistry , vol.29 , pp. 3673-3675
    • Zhang, Z.1    Jia, Z.2
  • 28
    • 0025973097 scopus 로고
    • Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-b-lactams through chiral ester enolate-imine cyclocondensation
    • Ojima, I., Habus, I., Zhao, M., Georg, G.I., and Jayasinghe, R. (1991) Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-b-lactams through chiral ester enolate-imine cyclocondensation. The Journal of Organic Chemistry, 56, 1681-1683.
    • (1991) The Journal of Organic Chemistry , vol.56 , pp. 1681-1683
    • Ojima, I.1    Habus, I.2    Zhao, M.3    Georg, G.I.4    Jayasinghe, R.5
  • 29
    • 0026686518 scopus 로고
    • New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of b-lactam synthon method
    • Ojima, I., Habus, I., Zhao, M., Zucco, M., Park, Y.H., Sun, C.-M., and Brigaud, T. (1992) New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of b-lactam synthon method. Tetrahedron, 48, 6985-7012.
    • (1992) Tetrahedron , vol.48 , pp. 6985-7012
    • Ojima, I.1    Habus, I.2    Zhao, M.3    Zucco, M.4    Park, Y.H.5    Sun, C.-M.6    Brigaud, T.7
  • 31
    • 0028302451 scopus 로고
    • Expeditious semisynthesis of docetaxel using 2-trichloromethyl-1,3-oxazolidine as side-chain protection
    • Didier, E., Fouque, E., and Commerçon, A. (1994) Expeditious semisynthesis of docetaxel using 2-trichloromethyl-1,3-oxazolidine as side-chain protection. Tetrahedron Letters, 35, 3063-3064.
    • (1994) Tetrahedron Letters , vol.35 , pp. 3063-3064
    • Didier, E.1    Fouque, E.2    Commerçon, A.3
  • 32
    • 0028213554 scopus 로고
    • 2-Monosubstituted-1,3-oxazolidines as improved protective groups of N-Boc-phenylisoserine in docetaxel preparation
    • Didier, E., Fouque, E., Taillepied, I., and Commerçon, A. (1994) 2-Monosubstituted-1,3-oxazolidines as improved protective groups of N-Boc-phenylisoserine in docetaxel preparation. Tetrahedron Letters, 35, 2349-2352.
    • (1994) Tetrahedron Letters , vol.35 , pp. 2349-2352
    • Didier, E.1    Fouque, E.2    Taillepied, I.3    Commerçon, A.4
  • 33
    • 0032790361 scopus 로고    scopus 로고
    • A new semisynthesis of paclitaxel from baccatin III
    • Baloglu, E. and Kingston, D.G.I. (1999) A new semisynthesis of paclitaxel from baccatin III. Journal of Natural Products, 62, 1068-1071.
    • (1999) Journal of Natural Products , vol.62 , pp. 1068-1071
    • Baloglu, E.1    Kingston, D.G.I.2
  • 49
    • 84926449688 scopus 로고    scopus 로고
    • Greener Synthetic Pathways Award: Bristol-Myers Squibb Company: Development of a Green Synthesis for TAXOL Manufacture via Plant Cell Fermentation and Extraction
    • Agency, U.E.P. (2004) Greener Synthetic Pathways Award: Bristol-Myers Squibb Company: Development of a Green Synthesis for TAXOL Manufacture via Plant Cell Fermentation and Extraction, www.epa.gov/greenchemistry/pubs/pgcc/winners/gspa04.html.
    • (2004)
    • Agency, U.E.P.1
  • 52
    • 0027033799 scopus 로고
    • Cell culture of Taxus as a source of the antineoplastic drug taxol and related taxanes
    • Fett-Neto, A.G., DiCosmo, F., Reynolds, W.F., and Sakata, K. (1992) Cell culture of Taxus as a source of the antineoplastic drug taxol and related taxanes. Bio/ Technology, 10, 1572-1575.
    • (1992) Bio/ Technology , vol.10 , pp. 1572-1575
    • Fett-neto, A.G.1    DiCosmo, F.2    Reynolds, W.F.3    Sakata, K.4
  • 53
    • 14744288106 scopus 로고
    • Taxol: out of the woods
    • Edgington, S.M. (1991) Taxol: out of the woods. Bio/Technology, 9, 933-938.
    • (1991) Bio/Technology , vol.9 , pp. 933-938
    • Edgington, S.M.1
  • 55
    • 0027270462 scopus 로고
    • Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew
    • Stierle, A., Strobel, G., and Stierle, D. (1993) Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew. Science, 260, 214-216.
    • (1993) Science , vol.260 , pp. 214-216
    • Stierle, A.1    Strobel, G.2    Stierle, D.3
  • 56
    • 0034672382 scopus 로고    scopus 로고
    • Taxol from Tubercularia sp. strain TF5, an endophytic fungus of Taxus mairei
    • Wang, J., Li, G., Lu, H., Zheng, Z., Huang, Y., and Su, W. (2000) Taxol from Tubercularia sp. strain TF5, an endophytic fungus of Taxus mairei. FEMS Microbiology Letters, 193, 249-253.
    • (2000) FEMS Microbiology Letters , vol.193 , pp. 249-253
    • Wang, J.1    Li, G.2    Lu, H.3    Zheng, Z.4    Huang, Y.5    Su, W.6
  • 60
    • 0025850566 scopus 로고
    • Sequences of taxol and cisplatin: a phase I and pharmacologic study
    • Rowinsky, E.K., Gilbert, M., and McGuire, W.P. (1991) Sequences of taxol and cisplatin: a phase I and pharmacologic study. Journal of Clinical Oncology, 9, 1692-1703.
    • (1991) Journal of Clinical Oncology , vol.9 , pp. 1692-1703
    • Rowinsky, E.K.1    Gilbert, M.2    McGuire, W.P.3
  • 61
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
    • McGuire, W.P., Hoskins, W.J., and Brady, M.F. (1996) Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer. New England Journal of Medicine, 334, 1-6.
    • (1996) New England Journal of Medicine , vol.334 , pp. 1-6
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3
  • 63
    • 0029063397 scopus 로고
    • Structure of tubulin at 6.5 A and location of the taxol-binding site
    • Nogales, E., Wolf, S., Khan, I., Luduena, R., and Downing, K. (1995) Structure of tubulin at 6.5 A and location of the taxol-binding site. Nature, 375, 424-427.
    • (1995) Nature , vol.375 , pp. 424-427
    • Nogales, E.1    Wolf, S.2    Khan, I.3    Luduena, R.4    Downing, K.5
  • 64
    • 0026682713 scopus 로고
    • Low resolution structure of microtubules in solution: synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in comparison with glycerol and MAP-induced microtubules
    • Andreu, J.M., Bordas, J., Diaz, J.F., deAncos, J.G., Gil, R., Medrano, F.J., Nogales, E., Pantos, E., and Towns-Andrews, E. (1992) Low resolution structure of microtubules in solution: synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in comparison with glycerol and MAP-induced microtubules. Journal of Molecular Biology, 226, 169-184.
    • (1992) Journal of Molecular Biology , vol.226 , pp. 169-184
    • Andreu, J.M.1    Bordas, J.2    Diaz, J.F.3    deAncos, J.G.4    Gil, R.5    Medrano, F.J.6    Nogales, E.7    Pantos, E.8    Towns-andrews, E.9
  • 65
    • 0032509226 scopus 로고    scopus 로고
    • Changes in microtubule protofilament number induced by taxol binding to an easily accessible site
    • Diaz, J., Valpuesta, J., Chacon, P., Diakun, G., and Andreu, J. (1998) Changes in microtubule protofilament number induced by taxol binding to an easily accessible site. The Journal of Biological Chemistry, 272, 33803-33810.
    • (1998) The Journal of Biological Chemistry , vol.272 , pp. 33803-33810
    • Diaz, J.1    Valpuesta, J.2    Chacon, P.3    Diakun, G.4    Andreu, J.5
  • 69
    • 0032006059 scopus 로고    scopus 로고
    • Microtubules and actin filaments: dynamic targets for cancer chemotherapy
    • Jordan, M. and Wilson, L. (1998) Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Current Opinion in Cell Biology, 10, 123-130.
    • (1998) Current Opinion in Cell Biology , vol.10 , pp. 123-130
    • Jordan, M.1    Wilson, L.2
  • 70
    • 0028070358 scopus 로고
    • Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase
    • Long, B. and Fairchild, C. (1994) Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase. Cancer Research, 54, 4355-4361.
    • (1994) Cancer Research , vol.54 , pp. 4355-4361
    • Long, B.1    Fairchild, C.2
  • 71
    • 0028241451 scopus 로고
    • Cytotoxicity of the anti-cancer agents cisplatin and taxol during cell proliferation and the cell cycle
    • Donaldson, K., Goolsby, G., and Wahl, A. (1994) Cytotoxicity of the anti-cancer agents cisplatin and taxol during cell proliferation and the cell cycle. International Journal of Cancer, 57, 847-855.
    • (1994) International Journal of Cancer , vol.57 , pp. 847-855
    • Donaldson, K.1    Goolsby, G.2    Wahl, A.3
  • 73
    • 0036184739 scopus 로고    scopus 로고
    • Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460
    • Huisman, C., Ferreira, C., Broker, L., Rodriguez, J., Smit, E., Postmus, P., Kruyt, F., and Giaccone, G. (2002) Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. Clinical Cancer Research, 8, 596-606.
    • (2002) Clinical Cancer Research , vol.8 , pp. 596-606
    • Huisman, C.1    Ferreira, C.2    Broker, L.3    Rodriguez, J.4    Smit, E.5    Postmus, P.6    Kruyt, F.7    Giaccone, G.8
  • 75
    • 70349974226 scopus 로고    scopus 로고
    • Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules
    • Mielgo, A., Torres, V., Clair, K., Barbero, S., and Stupack, D. (2009) Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene, 28, 3551-3562.
    • (2009) Oncogene , vol.28 , pp. 3551-3562
    • Mielgo, A.1    Torres, V.2    Clair, K.3    Barbero, S.4    Stupack, D.5
  • 77
    • 0001554639 scopus 로고    scopus 로고
    • Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells
    • Shtil, A., Madlekar, S., Yu, R., Walter, R., Hagen, K., Tan, T., Roninson, I., and Kong, A. (1999) Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells. Oncogene, 18, 377-384.
    • (1999) Oncogene , vol.18 , pp. 377-384
    • Shtil, A.1    Madlekar, S.2    Yu, R.3    Walter, R.4    Hagen, K.5    Tan, T.6    Roninson, I.7    Kong, A.8
  • 78
    • 0034685876 scopus 로고    scopus 로고
    • Microtubule-interfering agents stimulate the transcription of cyclooxygenase: 2. Evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways
    • Subbaramaiah, K., Hart, J., Norton, L., and Dannenberg, A. (2000) Microtubule-interfering agents stimulate the transcription of cyclooxygenase: 2. Evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways. The Journal of Biological Chemistry, 275, 14838-14845.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 14838-14845
    • Subbaramaiah, K.1    Hart, J.2    Norton, L.3    Dannenberg, A.4
  • 79
    • 0032883001 scopus 로고    scopus 로고
    • Molecular effects of paclitaxel: myths and reality (a critical review)
    • Blagosklonny, M. and Fojo, T. (1999) Molecular effects of paclitaxel: myths and reality (a critical review). International Journal of Cancer, 83, 151-156.
    • (1999) International Journal of Cancer , vol.83 , pp. 151-156
    • Blagosklonny, M.1    Fojo, T.2
  • 80
    • 0029964257 scopus 로고    scopus 로고
    • Taxol induces Bcl-2 phosphorylation and death of prostate cancer cells
    • Haldar, S., Chintapalli, J., and Croce, C. (1996) Taxol induces Bcl-2 phosphorylation and death of prostate cancer cells. Cancer Research, 56, 1253-1255.
    • (1996) Cancer Research , vol.56 , pp. 1253-1255
    • Haldar, S.1    Chintapalli, J.2    Croce, C.3
  • 81
    • 0031035693 scopus 로고    scopus 로고
    • Bcl2 is the guardian of microtubule integrity
    • Haldar, S., Basu, A., and Croce, C. (1997) Bcl2 is the guardian of microtubule integrity. Cancer Research, 57, 229-233.
    • (1997) Cancer Research , vol.57 , pp. 229-233
    • Haldar, S.1    Basu, A.2    Croce, C.3
  • 83
    • 0030615086 scopus 로고    scopus 로고
    • Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human AML HL-60 cells
    • Ibrado, A., Liu, L., and Bhalla, K. (1997) Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human AML HL-60 cells. Cancer Research, 57, 1109-1115.
    • (1997) Cancer Research , vol.57 , pp. 1109-1115
    • Ibrado, A.1    Liu, L.2    Bhalla, K.3
  • 84
    • 1242272838 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells
    • Chun, E. and Lee, K.-Y. (2004) Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells. Biochemical and Biophysical Research Communications, 315, 771-779.
    • (2004) Biochemical and Biophysical Research Communications , vol.315 , pp. 771-779
    • Chun, E.1    Lee, K.-Y.2
  • 85
    • 0031687587 scopus 로고    scopus 로고
    • Bcl-2 overexpression is associated with resistance to paclitaxel, but not gemcitabine, in multiple myeloma cells
    • Gazitt, Y., Rothenberg, M., Hilsenback, S., Fey, V., Thomas, C., and Montegomrey, W. (1998) Bcl-2 overexpression is associated with resistance to paclitaxel, but not gemcitabine, in multiple myeloma cells. International Journal of Oncology, 13, 839-848.
    • (1998) International Journal of Oncology , vol.13 , pp. 839-848
    • Gazitt, Y.1    Rothenberg, M.2    Hilsenback, S.3    Fey, V.4    Thomas, C.5    Montegomrey, W.6
  • 87
    • 33646417913 scopus 로고    scopus 로고
    • Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index
    • Callagy, G., Pharoah, P., and Pinder, S. (2006) Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index. Clinical Cancer Research, 12, 2468-2475.
    • (2006) Clinical Cancer Research , vol.12 , pp. 2468-2475
    • Callagy, G.1    Pharoah, P.2    Pinder, S.3
  • 88
    • 33750723137 scopus 로고    scopus 로고
    • Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
    • Yoshino, T., Shiina, H., and Urakami, S. (2006) Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy. Clinical Cancer Research, 12, 6116-6125.
    • (2006) Clinical Cancer Research , vol.12 , pp. 6116-6125
    • Yoshino, T.1    Shiina, H.2    Urakami, S.3
  • 90
    • 3042645219 scopus 로고    scopus 로고
    • Molecular mechanisms of the effects of low concentrations of taxol in anaplastic thyroid cancer cells
    • Pushkarev, V., Starenki, D., Saenko, V., Namba, H., Kurebayashi, J., Tronko, M., and Yamashita, S. (2004) Molecular mechanisms of the effects of low concentrations of taxol in anaplastic thyroid cancer cells. Endocrinology, 145, 3143-3152.
    • (2004) Endocrinology , vol.145 , pp. 3143-3152
    • Pushkarev, V.1    Starenki, D.2    Saenko, V.3    Namba, H.4    Kurebayashi, J.5    Tronko, M.6    Yamashita, S.7
  • 92
    • 0035136965 scopus 로고    scopus 로고
    • Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells
    • Shiah, S., Chuang, S., and Kuo, M. (2001) Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells. Molecular Pharmacology, 59, 254-262.
    • (2001) Molecular Pharmacology , vol.59 , pp. 254-262
    • Shiah, S.1    Chuang, S.2    Kuo, M.3
  • 93
    • 0029913172 scopus 로고    scopus 로고
    • Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway
    • Blagosklonny, M., Schulte, T., Nguyen, P., Trepel, J., and Neckers, L. (1996) Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Research, 56, 1851-1854.
    • (1996) Cancer Research , vol.56 , pp. 1851-1854
    • Blagosklonny, M.1    Schulte, T.2    Nguyen, P.3    Trepel, J.4    Neckers, L.5
  • 94
    • 0033542382 scopus 로고    scopus 로고
    • Serine protease inhibitor TPCK prevents taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells
    • Huang, Y., Sheikh, M., Fornance, A., and Holbrook, N. (1999) Serine protease inhibitor TPCK prevents taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells. Oncogene, 18, 3431-3439.
    • (1999) Oncogene , vol.18 , pp. 3431-3439
    • Huang, Y.1    Sheikh, M.2    Fornance, A.3    Holbrook, N.4
  • 95
    • 70450257737 scopus 로고    scopus 로고
    • The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts
    • Ahn, J.-H., Eum, K.-H., and Lee, M. (2009) The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts. Molecular and Cellular Biochemistry, 332, 189-197.
    • (2009) Molecular and Cellular Biochemistry , vol.332 , pp. 189-197
    • Ahn, J.-H.1    Eum, K.-H.2    Lee, M.3
  • 96
    • 0035377357 scopus 로고    scopus 로고
    • Paclitaxel induces prolonged activation of the Ras/ MEK/ERK pathway independently of activating the programmed cell death machinery
    • Okano, J.-I. and Rustgi, A. (2001) Paclitaxel induces prolonged activation of the Ras/ MEK/ERK pathway independently of activating the programmed cell death machinery. The Journal of Biological Chemistry, 276, 19555-19564.
    • (2001) The Journal of Biological Chemistry , vol.276 , pp. 19555-19564
    • Okano, J.-I.1    Rustgi, A.2
  • 99
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. and Pastan, I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annual Review of Biochemistry, 62, 385-427.
    • (1993) Annual Review of Biochemistry , vol.62 , pp. 385-427
    • Gottesman, M.1    Pastan, I.2
  • 100
    • 0037282898 scopus 로고    scopus 로고
    • Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression
    • Yeh, J., Hsu, W., Wang, J., Ho, S., and Kao, A. (2003) Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression. Respiration; International Review of Thoracic Diseases, 70, 32-35.
    • (2003) Respiration; International Review of Thoracic Diseases , vol.70 , pp. 32-35
    • Yeh, J.1    Hsu, W.2    Wang, J.3    Ho, S.4    Kao, A.5
  • 101
    • 1842477895 scopus 로고    scopus 로고
    • Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples
    • Penson, R., Oliva, E., Skates, S., Glyptis, T., Fuller, A.J., Goodman, A., and Selden, M. (2004) Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples. Gynecologic Oncology, 93, 98-106.
    • (2004) Gynecologic Oncology , vol.93 , pp. 98-106
    • Penson, R.1    Oliva, E.2    Skates, S.3    Glyptis, T.4    Fuller, A.J.5    Goodman, A.6    Selden, M.7
  • 103
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • Leonard, G., Fojo, T., and Bates, S. (2003) The role of ABC transporters in clinical practice. Oncologist, 8, 411-424.
    • (2003) Oncologist , vol.8 , pp. 411-424
    • Leonard, G.1    Fojo, T.2    Bates, S.3
  • 104
    • 0345688612 scopus 로고    scopus 로고
    • Mechanisms of taxol resistance related to microtubules
    • Orr, G., Verdier-Pinard, P., McDaid, H., and Horwitz, S. (2003) Mechanisms of taxol resistance related to microtubules. Oncogene, 22, 7280-7295.
    • (2003) Oncogene , vol.22 , pp. 7280-7295
    • Orr, G.1    Verdier-pinard, P.2    McDaid, H.3    Horwitz, S.4
  • 109
    • 0031985608 scopus 로고    scopus 로고
    • Altered b-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells
    • Ranganathan, S., Benetatos, C., Colarusso, P., Dexter, D., and Hudes, G. (1998) Altered b-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells. British Journal of Cancer, 77, 562-566.
    • (1998) British Journal of Cancer , vol.77 , pp. 562-566
    • Ranganathan, S.1    Benetatos, C.2    Colarusso, P.3    Dexter, D.4    Hudes, G.5
  • 110
  • 112
    • 0034807154 scopus 로고    scopus 로고
    • Expression of b-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen correlation with sensitivity to microtubule active agents
    • Nicoletti, M., Valoti, G., Giannakakou, P., Zhan, Z., Kim, J., Lucchini, V., Landoni, F., Mayo, J., Giavazzi, R., and Fojo, T. (2001) Expression of b-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen correlation with sensitivity to microtubule active agents. Clinical Cancer Research, 7, 2912-2922.
    • (2001) Clinical Cancer Research , vol.7 , pp. 2912-2922
    • Nicoletti, M.1    Valoti, G.2    Giannakakou, P.3    Zhan, Z.4    Kim, J.5    Lucchini, V.6    Landoni, F.7    Mayo, J.8    Giavazzi, R.9    Fojo, T.10
  • 116
    • 0000052734 scopus 로고
    • Taxol and Taxotere: discovery, chemistry, and structure-activity relationships
    • Guenard, D., Gueritte-Voegelein, F., and Potier, P. (1993) Taxol and Taxotere: discovery, chemistry, and structure-activity relationships. Accounts of Chemical Research, 26, 160-167.
    • (1993) Accounts of Chemical Research , vol.26 , pp. 160-167
    • Guenard, D.1    Gueritte-voegelein, F.2    Potier, P.3
  • 118
    • 77957102852 scopus 로고    scopus 로고
    • Recent advances in the medicinal chemistry of taxoid anticancer agents
    • (B.E. Maryanoff and A.B. Reitz), JAI Press, Greenwich, CT
    • Ojima, I., Kuduk, S.D., and Chakravarty, S. (1998) Recent advances in the medicinal chemistry of taxoid anticancer agents, in Advances in Medicinal Chemistry (eds B.E. Maryanoff and A.B. Reitz), JAI Press, Greenwich, CT, pp. 69-124.
    • (1998) Advances in Medicinal Chemistry , pp. 69-124
    • Ojima, I.1    Kuduk, S.D.2    Chakravarty, S.3
  • 119
    • 0034041275 scopus 로고    scopus 로고
    • Recent advances in the chemistry of taxol
    • Kingston, D.G. (2000) Recent advances in the chemistry of taxol. Journal of Natural Products, 63, 726-734.
    • (2000) Journal of Natural Products , vol.63 , pp. 726-734
    • Kingston, D.G.1
  • 121
    • 65249131138 scopus 로고    scopus 로고
    • Recent advances in the chemistry and biology of new generation taxoids
    • Ojima, I. and Das, M. (2009) Recent advances in the chemistry and biology of new generation taxoids. Journal of Natural Products, 72, 554-565.
    • (2009) Journal of Natural Products , vol.72 , pp. 554-565
    • Ojima, I.1    Das, M.2
  • 122
    • 0023905721 scopus 로고
    • Modified taxols: 4. Synthesis and biological activity of taxols modified in the C13 side chain
    • Magri, N.F. and Kingston, D.G.I. (1988) Modified taxols: 4. Synthesis and biological activity of taxols modified in the C13 side chain. Journal of Natural Products, 51, 298-306.
    • (1988) Journal of Natural Products , vol.51 , pp. 298-306
    • Magri, N.F.1    Kingston, D.G.I.2
  • 124
    • 0027935479 scopus 로고
    • Synthesis and structure-activity relationships of new antitumor taxoids: effects of cyclohexyl substitution at the C-3 and/or C-2 of Taxotere (Docetaxel)
    • Ojima, I., Duclos, O., Zucco, M., Bissery, M.-C., Combeau, C., Vrignaud, P., Riou, J.F., and Lavelle, F. (1994) Synthesis and structure-activity relationships of new antitumor taxoids: effects of cyclohexyl substitution at the C-3 and/or C-2 of Taxotere (Docetaxel). Journal of Medicinal Chemistry, 37, 2602-2608.
    • (1994) Journal of Medicinal Chemistry , vol.37 , pp. 2602-2608
    • Ojima, I.1    Duclos, O.2    Zucco, M.3    Bissery, M.-C.4    Combeau, C.5    Vrignaud, P.6    Riou, J.F.7    Lavelle, F.8
  • 126
    • 0033581642 scopus 로고    scopus 로고
    • Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "Hydrophobic Collapse" conformation
    • Boge, T.C., Wu, Z.-J., Himes, R.H., Vander Velde, D.G., and Georg, G.I. (1999) Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "Hydrophobic Collapse" conformation. Bioorganic & Medicinal Chemistry Letters, 9, 3047-3052.
    • (1999) Bioorganic & Medicinal Chemistry Letters , vol.9 , pp. 3047-3052
    • Boge, T.C.1    Wu, Z.-J.2    Himes, R.H.3    Vander Velde, D.G.4    Georg, G.I.5
  • 128
    • 0028825869 scopus 로고
    • A new paclitaxel photoaffinity analog with a 3-(4-benzoylphenyl)propanoyl probe for characterization of drug-binding sites on tubulin and P-glycoprotein
    • Ojima, I., Duclos, O., Dormán, G., Simonot, B., Prestwich, G.D., Rao, S., Lerro, K.A., and Horwitz, S.B. (1995) A new paclitaxel photoaffinity analog with a 3-(4-benzoylphenyl)propanoyl probe for characterization of drug-binding sites on tubulin and P-glycoprotein. Journal of Medicinal Chemistry, 38, 3891-3894.
    • (1995) Journal of Medicinal Chemistry , vol.38 , pp. 3891-3894
    • Ojima, I.1    Duclos, O.2    Dormán, G.3    Simonot, B.4    Prestwich, G.D.5    Rao, S.6    Lerro, K.A.7    Horwitz, S.B.8
  • 138
    • 0001400169 scopus 로고    scopus 로고
    • Studies on the chemistry of taxol
    • Kingston, D.G.I. (1998) Studies on the chemistry of taxol. Pure and Applied Chemistry, 70, 331-334.
    • (1998) Pure and Applied Chemistry , vol.70 , pp. 331-334
    • Kingston, D.G.I.1
  • 139
    • 0034714179 scopus 로고    scopus 로고
    • Synthesis and biological activity of C-6 and C-7 modified paclitaxels
    • Yuan, H., Fairchild, C.R., Liang, X., and Kingston, D.G.I. (2000) Synthesis and biological activity of C-6 and C-7 modified paclitaxels. Tetrahedron, 56, 6407-6414.
    • (2000) Tetrahedron , vol.56 , pp. 6407-6414
    • Yuan, H.1    Fairchild, C.R.2    Liang, X.3    Kingston, D.G.I.4
  • 141
    • 0033529688 scopus 로고    scopus 로고
    • Synthesis and biological activity of a novel C4-C6 bridged paclitaxel analog
    • Yuan, H., Kingston, D.G.I., Sackett, D.L., and Hamel, E. (1999) Synthesis and biological activity of a novel C4-C6 bridged paclitaxel analog. Tetrahedron, 55, 9707-9716.
    • (1999) Tetrahedron , vol.55 , pp. 9707-9716
    • Yuan, H.1    Kingston, D.G.I.2    Sackett, D.L.3    Hamel, E.4
  • 142
    • 0028939437 scopus 로고
    • Reaction of paclitaxel and 10-desacetyl baccatin III with diethylamino sulfurtrifluoride
    • Roth, G.P., Marshall, D.R., and Chen, S.-H. (1995) Reaction of paclitaxel and 10-desacetyl baccatin III with diethylamino sulfurtrifluoride. Tetrahedron Letters, 36, 1609-1612.
    • (1995) Tetrahedron Letters , vol.36 , pp. 1609-1612
    • Roth, G.P.1    Marshall, D.R.2    Chen, S.-H.3
  • 143
    • 0028806691 scopus 로고
    • Highly water soluble taxol derivatives: 7-polyethylene glycol carbamates and carbonates
    • Greenwald, R.B., Pendri, A., and Bolikal, D. (1995) Highly water soluble taxol derivatives: 7-polyethylene glycol carbamates and carbonates. The Journal of Organic Chemistry, 60, 331-336.
    • (1995) The Journal of Organic Chemistry , vol.60 , pp. 331-336
    • Greenwald, R.B.1    Pendri, A.2    Bolikal, D.3
  • 146
    • 0027244913 scopus 로고
    • Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol
    • Chen, S.-H., Fairchild, C., Mamber, S.W., and Farina, V. (1993) Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol. The Journal of Organic Chemistry, 58, 2927-2928.
    • (1993) The Journal of Organic Chemistry , vol.58 , pp. 2927-2928
    • Chen, S.-H.1    Fairchild, C.2    Mamber, S.W.3    Farina, V.4
  • 148
    • 0033621479 scopus 로고    scopus 로고
    • Characterization of the taxol binding site on the microtubule: identification of Arg282 in b-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol
    • Rao, S., He, L., Chakravarty, S., Ojima, I., Orr, G., and Horwitz, S. (1999) Characterization of the taxol binding site on the microtubule: identification of Arg282 in b-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol. The Journal of Biological Chemistry, 274, 37990-37994.
    • (1999) The Journal of Biological Chemistry , vol.274 , pp. 37990-37994
    • Rao, S.1    He, L.2    Chakravarty, S.3    Ojima, I.4    Orr, G.5    Horwitz, S.6
  • 151
    • 0029417352 scopus 로고
    • Altered expression of M2, the class II-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance
    • Haber, M., Burkhart, C.A., Regl, D.L., Madafiglio, J., Norris, M.D., and Horwitz, S.B. (1995) Altered expression of M2, the class II-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance. The Journal of Biological Chemistry, 270, 31269-31275.
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 31269-31275
    • Haber, M.1    Burkhart, C.A.2    Regl, D.L.3    Madafiglio, J.4    Norris, M.D.5    Horwitz, S.B.6
  • 152
    • 0032904694 scopus 로고    scopus 로고
    • Antisense oligonucleotides to class III b-tubulin sensitize drug-resistant cells to taxol
    • Kavallaris, M., Burkhart, C.A., and Horwitz, S.B. (1999) Antisense oligonucleotides to class III b-tubulin sensitize drug-resistant cells to taxol. British Journal of Cancer, 80, 1020-1025.
    • (1999) British Journal of Cancer , vol.80 , pp. 1020-1025
    • Kavallaris, M.1    Burkhart, C.A.2    Horwitz, S.B.3
  • 153
  • 156
    • 0025871603 scopus 로고
    • Modified taxols: 5. Reaction of taxol with electrophilic reagents and preparation of a rearranged taxol derivative with tubulin assembly activity
    • Samaranayake, G., Magri, N.F., Jitrangsri, C., and Kingston, D.G.I. (1991) Modified taxols: 5. Reaction of taxol with electrophilic reagents and preparation of a rearranged taxol derivative with tubulin assembly activity. The Journal of Organic Chemistry, 56, 5114-5119.
    • (1991) The Journal of Organic Chemistry , vol.56 , pp. 5114-5119
    • Samaranayake, G.1    Magri, N.F.2    Jitrangsri, C.3    Kingston, D.G.I.4
  • 159
    • 0034728938 scopus 로고    scopus 로고
    • Synthesis of 5(20) deoxydocetaxel, a new active docetaxel analogue
    • Dubois, J., Thoret, S., Gueritte, F., and Guenard, D. (2000) Synthesis of 5(20) deoxydocetaxel, a new active docetaxel analogue. Tetrahedron Letters, 41, 3331-3334.
    • (2000) Tetrahedron Letters , vol.41 , pp. 3331-3334
    • Dubois, J.1    Thoret, S.2    Gueritte, F.3    Guenard, D.4
  • 163
    • 0031909425 scopus 로고    scopus 로고
    • New active paclitaxel glucuronide derivative with improved water solubility
    • Paradis, R. and Page, M. (1998) New active paclitaxel glucuronide derivative with improved water solubility. International Journal of Oncology, 12, 391-395.
    • (1998) International Journal of Oncology , vol.12 , pp. 391-395
    • Paradis, R.1    Page, M.2
  • 164
    • 0031857631 scopus 로고    scopus 로고
    • Antitumor activity of paclitaxel-2-glycinate conjugated to poly(ethylene glycol): a water-soluble prodrug
    • Pendri, A., Conover, C.D., and Greenwald, R.B. (1998) Antitumor activity of paclitaxel-2-glycinate conjugated to poly(ethylene glycol): a water-soluble prodrug. Anti-Cancer Drug Design, 13, 387-395.
    • (1998) Anti-Cancer Drug Design , vol.13 , pp. 387-395
    • Pendri, A.1    Conover, C.D.2    Greenwald, R.B.3
  • 165
    • 0035845748 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-human serum albumin-paclitaxel conjugates: preparation, characterization and pharmacokinetics
    • Dosio, F., Arpicco, S., Brusa, P., Stella, B., and Cattel, L. (2001) Poly(ethylene glycol)-human serum albumin-paclitaxel conjugates: preparation, characterization and pharmacokinetics. Journal of Controlled Release, 76, 107-117.
    • (2001) Journal of Controlled Release , vol.76 , pp. 107-117
    • Dosio, F.1    Arpicco, S.2    Brusa, P.3    Stella, B.4    Cattel, L.5
  • 166
    • 0034998446 scopus 로고    scopus 로고
    • Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility
    • Niethammer, A., Gaedicke, G., Lode, H.N., and Wrasidlo, W. (2001) Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility. Bioconjugate Chemistry, 12, 414-420.
    • (2001) Bioconjugate Chemistry , vol.12 , pp. 414-420
    • Niethammer, A.1    Gaedicke, G.2    Lode, H.N.3    Wrasidlo, W.4
  • 171
    • 24944590338 scopus 로고    scopus 로고
    • The taxol pharmacophore and the T-taxol bridging principle
    • Kingston, D., Bane, S., and Snyder, J. (2005) The taxol pharmacophore and the T-taxol bridging principle. Cell Cycle (Georgetown, Tex.), 4, 279-289.
    • (2005) Cell Cycle (Georgetown, Tex.) , vol.4 , pp. 279-289
    • Kingston, D.1    Bane, S.2    Snyder, J.3
  • 172
    • 0030750497 scopus 로고    scopus 로고
    • A novel approach to the study of solution structures and dynamic behavior of paclitaxel and docetaxel using fluorine-containing analogs as probes
    • Ojima, I., Kuduk, S.D., Chakravarty, S., Ourevitch, M., and Bégué, J.-P. (1997) A novel approach to the study of solution structures and dynamic behavior of paclitaxel and docetaxel using fluorine-containing analogs as probes. Journal of the American Chemical Society, 119, 5519-5527.
    • (1997) Journal of the American Chemical Society , vol.119 , pp. 5519-5527
    • Ojima, I.1    Kuduk, S.D.2    Chakravarty, S.3    Ourevitch, M.4    Bégué, J.-P.5
  • 173
    • 0032495513 scopus 로고    scopus 로고
    • Structure of the ab tubulin dimer by electron crystallography
    • Nogales, E., Wolf, S.G., and Downing, K.H. (1998) Structure of the ab tubulin dimer by electron crystallography. Nature, 391, 199-203.
    • (1998) Nature , vol.391 , pp. 199-203
    • Nogales, E.1    Wolf, S.G.2    Downing, K.H.3
  • 175
    • 0028861177 scopus 로고
    • Characterization of the taxol binding site on the microtubule: 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of b-tubulin
    • Rao, S., Orr, G.A., Chaudhary, A.G., Kingston, D.G.I., and Horwitz, S.B. (1995) Characterization of the taxol binding site on the microtubule: 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of b-tubulin. The Journal of Biological Chemistry, 270, 20235-20238.
    • (1995) The Journal of Biological Chemistry , vol.270 , pp. 20235-20238
    • Rao, S.1    Orr, G.A.2    Chaudhary, A.G.3    Kingston, D.G.I.4    Horwitz, S.B.5
  • 181
    • 67651115890 scopus 로고    scopus 로고
    • Recent advances in the study of the bioactive conformation of taxol
    • Sun, L., Simmerling, C., and Ojima, I. (2009) Recent advances in the study of the bioactive conformation of taxol. ChemMedChem, 4, 719-731.
    • (2009) ChemMedChem , vol.4 , pp. 719-731
    • Sun, L.1    Simmerling, C.2    Ojima, I.3
  • 187
    • 0037424365 scopus 로고    scopus 로고
    • Fast kinetics of taxol binding to microtubules: effects of solution variables and microtubule-associated proteins
    • Diaz, J., Barasoain, I., and Andreu, J. (2003) Fast kinetics of taxol binding to microtubules: effects of solution variables and microtubule-associated proteins. The Journal of Biological Chemistry, 278, 8407-8419.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 8407-8419
    • Diaz, J.1    Barasoain, I.2    Andreu, J.3
  • 189
    • 1542380040 scopus 로고    scopus 로고
    • Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization and cytotoxicity
    • Buey, R., Diaz, J., Andreu, J., O'Brate, A., Giannakakou, P., Nicolaou, K., Sasmal, P., Ritzen, A., and Namoto, K. (2004) Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization and cytotoxicity. Chemistry & Biology, 11, 225-236.
    • (2004) Chemistry & Biology , vol.11 , pp. 225-236
    • Buey, R.1    Diaz, J.2    Andreu, J.3    O'Brate, A.4    Giannakakou, P.5    Nicolaou, K.6    Sasmal, P.7    Ritzen, A.8    Namoto, K.9
  • 190
    • 0036321081 scopus 로고    scopus 로고
    • Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells
    • Lage, H. and Dietel, M.J. (2002) Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells. Journal of Cancer Research and Clinical Oncology, 128, 349-357.
    • (2002) Journal of Cancer Research and Clinical Oncology , vol.128 , pp. 349-357
    • Lage, H.1    Dietel, M.J.2
  • 193
    • 0031049783 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of non-aromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity
    • Ojima, I., Kuduk, S.D., Pera, P., Veith, J.M., and Bernacki, R.J. (1997) Synthesis and structure-activity relationships of non-aromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity. Journal of Medicinal Chemistry, 40, 279-285.
    • (1997) Journal of Medicinal Chemistry , vol.40 , pp. 279-285
    • Ojima, I.1    Kuduk, S.D.2    Pera, P.3    Veith, J.M.4    Bernacki, R.J.5
  • 198
    • 84889483761 scopus 로고    scopus 로고
    • Unique properties of fluorine and their relevance to medicinal chemistry and chemical biology
    • (I. Ojima), Wiley-Blackwell, Chichester
    • Yamazaki, T., Taguchi, T., and Ojima, I. (2009) Unique properties of fluorine and their relevance to medicinal chemistry and chemical biology, in Fluorine in Medicinal Chemistry and Chemical Biology (ed. I. Ojima), Wiley-Blackwell, Chichester, pp. 3-46.
    • (2009) Fluorine in Medicinal Chemistry and Chemical Biology , pp. 3-46
    • Yamazaki, T.1    Taguchi, T.2    Ojima, I.3
  • 203
    • 36749104372 scopus 로고    scopus 로고
    • Organofluorine chemistry at the biomedical interface: a case study on fluoro-taxoid anticancer agents
    • (V. Soloshonok, K. Mikami, T. Yamazaki, J.T. Welch, and J. Honek), American Chemical Society/Oxford University Press, Washington, DC
    • Ojima, I., Kuznetsova, L., and Sun, L. (2007) Organofluorine chemistry at the biomedical interface: a case study on fluoro-taxoid anticancer agents, in Current Fluoroorganic Chemistry: New Synthetic Directions, Technologies, Materials and Biological Applications, ACS Symposium Series 949 (eds V. Soloshonok, K. Mikami, T. Yamazaki, J.T. Welch, and J. Honek), American Chemical Society/Oxford University Press, Washington, DC, pp. 288-304.
    • (2007) Current Fluoroorganic Chemistry: New Synthetic Directions, Technologies, Materials and Biological Applications, ACS Symposium Series 949 , pp. 288-304
    • Ojima, I.1    Kuznetsova, L.2    Sun, L.3
  • 216
    • 0038419962 scopus 로고    scopus 로고
    • DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo
    • Shionoya, M., Jimbo, T., Kitagawa, M., Soga, T., and Tohgo, A. (2003) DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Science, 94, 459-466.
    • (2003) Cancer Science , vol.94 , pp. 459-466
    • Shionoya, M.1    Jimbo, T.2    Kitagawa, M.3    Soga, T.4    Tohgo, A.5
  • 217
    • 0028175036 scopus 로고
    • Paclitaxel (taxol) and docetaxel (Taxotere): not simply two of a kind
    • Verweij, J., Clavel, M., and Chevalier, B. (1994) Paclitaxel (taxol) and docetaxel (Taxotere): not simply two of a kind. Annals of Oncology, 5, 495-505.
    • (1994) Annals of Oncology , vol.5 , pp. 495-505
    • Verweij, J.1    Clavel, M.2    Chevalier, B.3
  • 220
    • 0029110526 scopus 로고
    • Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: preclinical experience
    • Bissery, M., Nohynek, G., Sanderink, G., and Lavelle, F. (1995) Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: preclinical experience. Anti-Cancer Drugs, 6, 339-355.
    • (1995) Anti-Cancer Drugs , vol.6 , pp. 339-355
    • Bissery, M.1    Nohynek, G.2    Sanderink, G.3    Lavelle, F.4
  • 222
    • 0028989720 scopus 로고
    • Docetaxel (Taxotere), a review of preclinical and clinical experience. Part II: clinical experience
    • Oosterom, A.V., Schrijvers, D., and Schrijvers, D. (1995) Docetaxel (Taxotere), a review of preclinical and clinical experience. Part II: clinical experience. Anti-Cancer Drugs, 6, 356-368.
    • (1995) Anti-Cancer Drugs , vol.6 , pp. 356-368
    • Oosterom, A.V.1    Schrijvers, D.2    Schrijvers, D.3
  • 225
    • 0028837396 scopus 로고
    • Docetaxel is a major cytotoxic drug for the treatment of advanced breast cancer: a phase II trial of the clinical screening cooperative group of the European organization for research and treatment of cancer
    • Chevallier, B., Fumoleau, P., Kerbrat, P., Dieras, V., Roche, H., Krakowski, I., Azli, N., Bayssas, M., Lentz, M., and Glabbeke, M.V. (1995) Docetaxel is a major cytotoxic drug for the treatment of advanced breast cancer: a phase II trial of the clinical screening cooperative group of the European organization for research and treatment of cancer. Journal of Clinical Oncology, 13, 314-322.
    • (1995) Journal of Clinical Oncology , vol.13 , pp. 314-322
    • Chevallier, B.1    Fumoleau, P.2    Kerbrat, P.3    Dieras, V.4    Roche, H.5    Krakowski, I.6    Azli, N.7    Bayssas, M.8    Lentz, M.9    Glabbeke, M.V.10
  • 227
  • 230
    • 11144229621 scopus 로고    scopus 로고
    • Approval summary: docetaxel in combination with prednisone for the treatment of androgen-independent hormone-refractory prostate cancer
    • Dagher, R., Li, N., Abraham, S., Rahman, A., Sridhara, R., and Pazdur, R. (2004) Approval summary: docetaxel in combination with prednisone for the treatment of androgen-independent hormone-refractory prostate cancer. Clinical Cancer Research, 10, 8147-8151.
    • (2004) Clinical Cancer Research , vol.10 , pp. 8147-8151
    • Dagher, R.1    Li, N.2    Abraham, S.3    Rahman, A.4    Sridhara, R.5    Pazdur, R.6
  • 234
    • 16244414000 scopus 로고    scopus 로고
    • Docetaxel for treatment of solid tumours: a systematic review of clinical data
    • Montero, A., Fossella, F., Hortobagyi, G., and Valero, V. (2005) Docetaxel for treatment of solid tumours: a systematic review of clinical data. The Lancet Oncology, 6, 229-239.
    • (2005) The Lancet Oncology , vol.6 , pp. 229-239
    • Montero, A.1    Fossella, F.2    Hortobagyi, G.3    Valero, V.4
  • 239
    • 84858701839 scopus 로고    scopus 로고
    • Efficacy results of node-negative HER2-amplified breast cancer subset from BCIRG 006 study: a phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin, and trastuzumab (TCH)
    • Valero, V., Slamon, D., Wiermann, W., Robert, N., Pienkowski, T., Martin, M., Mackey, J., Lindsay, M., Bee-Munteanu, V., Press, M., Sauter, G., and Crown, J. (2011) Efficacy results of node-negative HER2-amplified breast cancer subset from BCIRG 006 study: a phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin, and trastuzumab (TCH). Journal of Clinical Oncology, 29, s553.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. s553
    • Valero, V.1    Slamon, D.2    Wiermann, W.3    Robert, N.4    Pienkowski, T.5    Martin, M.6    Mackey, J.7    Lindsay, M.8    Bee-munteanu, V.9    Press, M.10    Sauter, G.11    Crown, J.12
  • 241
    • 84876291029 scopus 로고    scopus 로고
    • Epirubicin plus cyclophosphamide followed by docetaxel plus trastuzumab and bevacizumab as neoadjuvant therapy for HER2-positive locally advanced breast cancer (LABC) or as adjuvant therapy for HER2-positive pathologic stage III breast cancer (PS3BC): a phase II trial of the SNABP Foundation Research Group
    • Smith, J., Buyse, M., Rastogi, P., Geyer, Jr. C., Jacobs, S., Patocskai, E., and Wolmark, N. (2009) Epirubicin plus cyclophosphamide followed by docetaxel plus trastuzumab and bevacizumab as neoadjuvant therapy for HER2-positive locally advanced breast cancer (LABC) or as adjuvant therapy for HER2-positive pathologic stage III breast cancer (PS3BC): a phase II trial of the SNABP Foundation Research Group. Journal of Clinical Oncology, 27, s580.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. s580
    • Smith, J.1    Buyse, M.2    Rastogi, P.3    Geyer, C.4    Jacobs, S.5    Patocskai, E.6    Wolmark, N.7
  • 245
    • 84926507328 scopus 로고    scopus 로고
    • S-1 combined with bi-weekly docetaxel for non-small cell lung cancer previously treated with platinum-based chemotherapy: a phase II study of North Japan Lung Cancer Group (NJLCG0701)
    • Ishimoto, O., Sakakibara, T., Maemondo, M., Inoue, A., Matsubara, N., Morikawa, N., Okudera, K., Usui, K., Suzuki, T., Nukiwa, T., and Sugawara, S. (2012) S-1 combined with bi-weekly docetaxel for non-small cell lung cancer previously treated with platinum-based chemotherapy: a phase II study of North Japan Lung Cancer Group (NJLCG0701). Cancer and Clinical Oncology, 1, 108-117.
    • (2012) Cancer and Clinical Oncology , vol.1 , pp. 108-117
    • Ishimoto, O.1    Sakakibara, T.2    Maemondo, M.3    Inoue, A.4    Matsubara, N.5    Morikawa, N.6    Okudera, K.7    Usui, K.8    Suzuki, T.9    Nukiwa, T.10    Sugawara, S.11
  • 247
    • 38349167518 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study
    • Berthold, D., Pond, G., Soban, F., Wit, R.D., Eisenberger, M., and Tannock, I. (2008) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study. Journal of Clinical Oncology, 26, 242-245.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 242-245
    • Berthold, D.1    Pond, G.2    Soban, F.3    Wit, R.D.4    Eisenberger, M.5    Tannock, I.6
  • 248
    • 75249096926 scopus 로고    scopus 로고
    • A phase II study of neoadjuvant chemotherapy with docetaxel and bevacizumab in patients (pts) with high-risk localized prostate cancer: a Prostate Cancer Clinical Trials Consortium Trial
    • Oh, W., Febbo, P., Richie, J., Fennessy, F., Scibelli, G., Hayes, J., Choueiri, T., Tempany, C., Taplin, M., and Ross, R. (2009) A phase II study of neoadjuvant chemotherapy with docetaxel and bevacizumab in patients (pts) with high-risk localized prostate cancer: a Prostate Cancer Clinical Trials Consortium Trial. Journal of Clinical Oncology, 27, s5060.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. s5060
    • Oh, W.1    Febbo, P.2    Richie, J.3    Fennessy, F.4    Scibelli, G.5    Hayes, J.6    Choueiri, T.7    Tempany, C.8    Taplin, M.9    Ross, R.10
  • 250
    • 77956542827 scopus 로고    scopus 로고
    • Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel: final results of a multinational phase III trial (TROPIC)
    • de Bono, J.S., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J., Shen, L., Matthews, P., and Sartor, A. (2010) Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel: final results of a multinational phase III trial (TROPIC). Journal of Clinical Oncology, 28, s4508.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. s4508
    • de Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3    Hansen, S.4    Machiels, J.5    Shen, L.6    Matthews, P.7    Sartor, A.8
  • 252
    • 77954574658 scopus 로고    scopus 로고
    • Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203
    • Sun, W., Powell, M., O'Dwyer, P.J., Catalano, P., Ansari, R.H., and Benson, A.B. III (2010) Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. Journal of Clinical Oncology, 28, 2947-2951.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 2947-2951
    • Sun, W.1    Powell, M.2    O'Dwyer, P.J.3    Catalano, P.4    Ansari, R.H.5    Benson, A.B.6
  • 254
    • 77951204618 scopus 로고    scopus 로고
    • Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: results of a phase II clinical trial
    • Kelsen, D., Jhawer, M., Ilson, D., Tse, A., Randazzo, J., Robinson, E., Capanu, M., and Shah, M. (2009) Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: results of a phase II clinical trial. Journal of Clinical Oncology, 27, s4512.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. s4512
    • Kelsen, D.1    Jhawer, M.2    Ilson, D.3    Tse, A.4    Randazzo, J.5    Robinson, E.6    Capanu, M.7    Shah, M.8
  • 255
    • 79952355358 scopus 로고    scopus 로고
    • Phase II study of modified docetaxel, cisplatin, and fluororuacil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma
    • Shah, M., Jhawer, M., Ilson, D., Lefkowitz, R., Robinson, E., Capanu, M., and Kelsen, D. (2011) Phase II study of modified docetaxel, cisplatin, and fluororuacil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma. Journal of Clinical Oncology, 29, 868-874.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. 868-874
    • Shah, M.1    Jhawer, M.2    Ilson, D.3    Lefkowitz, R.4    Robinson, E.5    Capanu, M.6    Kelsen, D.7
  • 259
    • 79151485327 scopus 로고    scopus 로고
    • Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial
    • Lorch, J., Goloubeva, O., Haddad, R., Cullen, K., Sarlis, N., Tishler, R., Tan, M., Fasciano, J., Sammartino, D., and Posner, M. (2011) Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. The Lancet Oncology, 12, 153-159.
    • (2011) The Lancet Oncology , vol.12 , pp. 153-159
    • Lorch, J.1    Goloubeva, O.2    Haddad, R.3    Cullen, K.4    Sarlis, N.5    Tishler, R.6    Tan, M.7    Fasciano, J.8    Sammartino, D.9    Posner, M.10
  • 261
    • 81155155669 scopus 로고    scopus 로고
    • Health-related quality of life outcomes of docetaxel/carboplatin combination therapy vs. sequential therapy with docetaxel then carboplatin in patients with relapsed, platinum-sensitive ovarian cancer: results from a randomized clinical trial
    • Pokrzywinski, R., Secord, A., Havrilesky, L., Puls, L., Holloway, R., Lewandowski, G., Higgins, R., Nycum, L., Kohler, M., and Revicki, D. (2011) Health-related quality of life outcomes of docetaxel/carboplatin combination therapy vs. sequential therapy with docetaxel then carboplatin in patients with relapsed, platinum-sensitive ovarian cancer: results from a randomized clinical trial. Gynecologic Oncology, 123, 505-510.
    • (2011) Gynecologic Oncology , vol.123 , pp. 505-510
    • Pokrzywinski, R.1    Secord, A.2    Havrilesky, L.3    Puls, L.4    Holloway, R.5    Lewandowski, G.6    Higgins, R.7    Nycum, L.8    Kohler, M.9    Revicki, D.10
  • 262
    • 84862550763 scopus 로고    scopus 로고
    • A multicenter, randomized, phase 2 clinical trial to evaluate the efficacy and safety of combination docetaxel and carboplatin and sequential therapy with docetaxel then carboplatin in patients with recurrent platinum-sensitive ovarian cancer
    • Secord, A., Berchuck, A., Higgins, R., Nycum, L., Kohler, M., Puls, L., Holloway, R., Lewandowski, G., Valea, F., and Havrilesky, L. (2012) A multicenter, randomized, phase 2 clinical trial to evaluate the efficacy and safety of combination docetaxel and carboplatin and sequential therapy with docetaxel then carboplatin in patients with recurrent platinum-sensitive ovarian cancer. Cancer, 118, 3283-3293.
    • (2012) Cancer , vol.118 , pp. 3283-3293
    • Secord, A.1    Berchuck, A.2    Higgins, R.3    Nycum, L.4    Kohler, M.5    Puls, L.6    Holloway, R.7    Lewandowski, G.8    Valea, F.9    Havrilesky, L.10
  • 264
    • 1142291736 scopus 로고    scopus 로고
    • New anticancer agents and therapeutic strategies in development for solid cancers: a clinical perspective
    • Awada, A., Mano, M., Hendlisz, A., and Piccart, M. (2004) New anticancer agents and therapeutic strategies in development for solid cancers: a clinical perspective. Expert Review of Anticancer Therapy, 4, 53-60.
    • (2004) Expert Review of Anticancer Therapy , vol.4 , pp. 53-60
    • Awada, A.1    Mano, M.2    Hendlisz, A.3    Piccart, M.4
  • 266
    • 84860397235 scopus 로고    scopus 로고
    • Clinical development of cabazitaxel for the treatment of castration-resistant prostate cancer
    • Tao, C.-K., Seng, S., Oh, W., and Galsky, M. (2011) Clinical development of cabazitaxel for the treatment of castration-resistant prostate cancer. Clinical Medicine Insights: Oncology, 5, 163-169.
    • (2011) Clinical Medicine Insights: Oncology , vol.5 , pp. 163-169
    • Tao, C.-K.1    Seng, S.2    Oh, W.3    Galsky, M.4
  • 267
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomized open-label trial
    • Bono, J.D., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J.-P., Kocak, I., Gravis, G., Bodrogi, I., Mackenzie, M., Roessner, L.S.M., Gupta, S., and Sartor, A. (2010) Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomized open-label trial. Lancet, 376, 1147-1154.
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • Bono, J.D.1    Oudard, S.2    Ozguroglu, M.3    Hansen, S.4    Machiels, J.-P.5    Kocak, I.6    Gravis, G.7    Bodrogi, I.8    Mackenzie, M.9    Roessner, L.S.M.10    Gupta, S.11    Sartor, A.12
  • 269
    • 50849088935 scopus 로고    scopus 로고
    • A multicenter phase II study of XRP6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients
    • Pivot, X., Koralewski, P., Hidalgo, J., Chan, A., Goncalves, A., Schwartsmann, G., Assadourian, S., and Lotz, J. (2008) A multicenter phase II study of XRP6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients. Annals of Oncology, 19, 1547-1552.
    • (2008) Annals of Oncology , vol.19 , pp. 1547-1552
    • Pivot, X.1    Koralewski, P.2    Hidalgo, J.3    Chan, A.4    Goncalves, A.5    Schwartsmann, G.6    Assadourian, S.7    Lotz, J.8
  • 270
    • 77957332544 scopus 로고    scopus 로고
    • A dose-escalating study of XRP6258 in combination with capecitabine, in patients (pts) with metastatic breast cancer (MBC) progressing after anthracycline and taxane therapy
    • Besse-Hammer, T., Villanueva, C., Campone, M., Machiels, J., Awada, A., Magherini, E., Dubin, F., Semiond, D., and Pivot, X. (2009) A dose-escalating study of XRP6258 in combination with capecitabine, in patients (pts) with metastatic breast cancer (MBC) progressing after anthracycline and taxane therapy. Journal of Clinical Oncology, 27, s1053.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. s1053
    • Besse-hammer, T.1    Villanueva, C.2    Campone, M.3    Machiels, J.4    Awada, A.5    Magherini, E.6    Dubin, F.7    Semiond, D.8    Pivot, X.9
  • 271
    • 79953713649 scopus 로고    scopus 로고
    • A multicentre dose-escalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: a phase I/II study
    • Villanueva, C., Awada, A., Campone, M., Machiels, J., Besse, T., Magherini, E., Dubin, F., Semiond, D., and Pivot, X. (2011) A multicentre dose-escalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: a phase I/II study. European Journal of Cancer (Oxford, England: 1990), 47, 1037-1045.
    • (2011) European Journal of Cancer (Oxford, England: 1990) , vol.47 , pp. 1037-1045
    • Villanueva, C.1    Awada, A.2    Campone, M.3    Machiels, J.4    Besse, T.5    Magherini, E.6    Dubin, F.7    Semiond, D.8    Pivot, X.9
  • 272
    • 0035990845 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-hour or a 3-hour infusion in patients with advanced solid tumors
    • Sessa, C., Cuvier, C., Caldiera, S., Bauer, J., Bosch, S.V.D., Monnerat, C., Semiond, D., Perard, D., Lebecq, A., Besenval, M., and Marty, M. (2002) Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-hour or a 3-hour infusion in patients with advanced solid tumors. Annals of Oncology, 13, 1140-1150.
    • (2002) Annals of Oncology , vol.13 , pp. 1140-1150
    • Sessa, C.1    Cuvier, C.2    Caldiera, S.3    Bauer, J.4    Bosch, S.V.D.5    Monnerat, C.6    Semiond, D.7    Perard, D.8    Lebecq, A.9    Besenval, M.10    Marty, M.11
  • 276
    • 46249085475 scopus 로고    scopus 로고
    • Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy
    • Dieras, V., Limentani, S., Romieu, G., Tubiana-Huli, M., Lortholary, A., Kaufman, P., Girre, V., Besenval, M., and Valero, V. (2008) Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy. Annals of Oncology, 19, 1255-1260.
    • (2008) Annals of Oncology , vol.19 , pp. 1255-1260
    • Dieras, V.1    Limentani, S.2    Romieu, G.3    Tubiana-huli, M.4    Lortholary, A.5    Kaufman, P.6    Girre, V.7    Besenval, M.8    Valero, V.9
  • 277
  • 278
    • 58149140537 scopus 로고    scopus 로고
    • Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIB or stage IV non-small cell lung cancer
    • Zatloukal, P., Gervais, R., Vansteenkiste, J., Bosquee, L., Sessa, C., Brain, E., Dansin, E., Urban, T., Dohollou, N., Besenval, M., and Quoix, E. (2008) Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIB or stage IV non-small cell lung cancer. Journal of Thoracic Oncology, 3, 894-901.
    • (2008) Journal of Thoracic Oncology , vol.3 , pp. 894-901
    • Zatloukal, P.1    Gervais, R.2    Vansteenkiste, J.3    Bosquee, L.4    Sessa, C.5    Brain, E.6    Dansin, E.7    Urban, T.8    Dohollou, N.9    Besenval, M.10    Quoix, E.11
  • 279
    • 71449088216 scopus 로고    scopus 로고
    • A phase I study of larotaxel (XRP9881) administered in combination with carboplatin in chemotherapy-naïve patients with stage IIIB or stage IV non-small cell lung cancer
    • Robert, F., Harper, K., Ackerman, J., and Gupta, S. (2010) A phase I study of larotaxel (XRP9881) administered in combination with carboplatin in chemotherapy-naïve patients with stage IIIB or stage IV non-small cell lung cancer. Cancer Chemotherapy and Pharmacology, 65, 227-234.
    • (2010) Cancer Chemotherapy and Pharmacology , vol.65 , pp. 227-234
    • Robert, F.1    Harper, K.2    Ackerman, J.3    Gupta, S.4
  • 280
    • 1842843197 scopus 로고    scopus 로고
    • Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 598862) and tRA96023
    • Minderman, H., Brooks, T., Loughlin, K., Ojima, I., Bernacki, R., and Baer, M. (2004) Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 598862) and tRA96023. Cancer Chemotherapy and Pharmacology, 53, 363-369.
    • (2004) Cancer Chemotherapy and Pharmacology , vol.53 , pp. 363-369
    • Minderman, H.1    Brooks, T.2    Loughlin, K.3    Ojima, I.4    Bernacki, R.5    Baer, M.6
  • 283
    • 84867428493 scopus 로고    scopus 로고
    • An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59-8862) in patients with taxane-resistant non-small cell lung cancer
    • Gurtler, J., Pawel, J., Spiridonidis, C., Grossi, F., Larriba, J., Moscovici, M., Markovitz, E., Voliotis, D., and Gottfried, M. (2004) An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59-8862) in patients with taxane-resistant non-small cell lung cancer. Journal of Clinical Oncology, 22, s7136.
    • (2004) Journal of Clinical Oncology , vol.22 , pp. s7136
    • Gurtler, J.1    Pawel, J.2    Spiridonidis, C.3    Grossi, F.4    Larriba, J.5    Moscovici, M.6    Markovitz, E.7    Voliotis, D.8    Gottfried, M.9
  • 284
    • 59149092286 scopus 로고    scopus 로고
    • Phase II study of ortataxel in taxane-resistant breast cancer
    • Beer, M., Lenaz, L., and Amadori, D. (2008) Phase II study of ortataxel in taxane-resistant breast cancer. Journal of Clinical Oncology, 26, 1066.
    • (2008) Journal of Clinical Oncology , vol.26 , pp. 1066
    • Beer, M.1    Lenaz, L.2    Amadori, D.3
  • 286
    • 37749009044 scopus 로고    scopus 로고
    • A phase II study of DJ-927 as second-line therapy in patients (pts) with advanced gastric cancer (GC) who have failed a 5-FU non taxane based regimen
    • Evans, T., Dobrila, R., Berardi, R., Sumpter, K., Wall, L., Oyama, R., and Anthoney, D. (2006) A phase II study of DJ-927 as second-line therapy in patients (pts) with advanced gastric cancer (GC) who have failed a 5-FU non taxane based regimen. Journal of Clinical Oncology, 24, s4081.
    • (2006) Journal of Clinical Oncology , vol.24 , pp. s4081
    • Evans, T.1    Dobrila, R.2    Berardi, R.3    Sumpter, K.4    Wall, L.5    Oyama, R.6    Anthoney, D.7
  • 289
  • 291
    • 84871215302 scopus 로고    scopus 로고
    • Phase I dose-ranging, pharmacokinetic (PK) study of tesetaxel, a novel orally active tubulin-binding agent
    • Beeram, M., Papadopoulos, K., Patnaik, A., Qureshi, A., and Tolcher, A. (2010) Phase I dose-ranging, pharmacokinetic (PK) study of tesetaxel, a novel orally active tubulin-binding agent. Journal of Clinical Oncology, 28, ae13075.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. ae13075
    • Beeram, M.1    Papadopoulos, K.2    Patnaik, A.3    Qureshi, A.4    Tolcher, A.5
  • 292
    • 84926457684 scopus 로고    scopus 로고
    • An intersubject dose-escalation study of tesetaxel administered orally once every 3 weeks and once weekly for 3 consecutive weeks in patients with advanced or metastatic solid tumors
    • Beeram, M., Novick, S., Qureshi, A., Patnaik, A., Papadopoulos, K., and Tolcher, A. (2010) An intersubject dose-escalation study of tesetaxel administered orally once every 3 weeks and once weekly for 3 consecutive weeks in patients with advanced or metastatic solid tumors. Journal of Clinical Oncology, 28, 159.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 159
    • Beeram, M.1    Novick, S.2    Qureshi, A.3    Patnaik, A.4    Papadopoulos, K.5    Tolcher, A.6
  • 293
    • 82455162574 scopus 로고    scopus 로고
    • Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I dose-escalation study in patients with advanced solid tumors
    • Saif, M., Sarantopoulos, J., Patnaik, A., Tolcher, A., Takimoto, C., and Beeram, M. (2011) Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I dose-escalation study in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology, 68, 1565-1573.
    • (2011) Cancer Chemotherapy and Pharmacology , vol.68 , pp. 1565-1573
    • Saif, M.1    Sarantopoulos, J.2    Patnaik, A.3    Tolcher, A.4    Takimoto, C.5    Beeram, M.6
  • 298
    • 0028306775 scopus 로고
    • Taxuspines A-C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells
    • Kobayashi, J., Ogiwara, A., Hosoyama, H., Shigemori, H., Yoshida, N., Sasaki, T., Li, Y., Iwasaki, S., Naito, M., and Tsuruo, T. (1994) Taxuspines A-C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. Tetrahedron, 50, 7401-7416.
    • (1994) Tetrahedron , vol.50 , pp. 7401-7416
    • Kobayashi, J.1    Ogiwara, A.2    Hosoyama, H.3    Shigemori, H.4    Yoshida, N.5    Sasaki, T.6    Li, Y.7    Iwasaki, S.8    Naito, M.9    Tsuruo, T.10
  • 300
    • 84926451065 scopus 로고    scopus 로고
    • Discovery and development of new taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells
    • Ojima, I., Bounaud, P.-Y., Pera, P., and Bernacki, R. (1998) Discovery and development of new taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells. Annals of Oncology, 9, s557.
    • (1998) Annals of Oncology , vol.9 , pp. s557
    • Ojima, I.1    Bounaud, P.-Y.2    Pera, P.3    Bernacki, R.4
  • 303
    • 3242717109 scopus 로고    scopus 로고
    • Taxane-based reversal agent modulation of P-glycoprotein-, multidrug resistance protein- and breast cancer resistance protein-mediated drug transport
    • Brooks, T., Minderman, H., O'Loughlin, K., Ojima, I., Baer, M., and Bernacki, R. (2003) Taxane-based reversal agent modulation of P-glycoprotein-, multidrug resistance protein- and breast cancer resistance protein-mediated drug transport. Molecular Cancer Therapeutics, 2, 1195-1205.
    • (2003) Molecular Cancer Therapeutics , vol.2 , pp. 1195-1205
    • Brooks, T.1    Minderman, H.2    O'Loughlin, K.3    Ojima, I.4    Baer, M.5    Bernacki, R.6
  • 304
    • 2442446415 scopus 로고    scopus 로고
    • Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators
    • Brooks, T., Kennedy, D., Gruol, D., Ojima, I., Baer, M., and Bernacki, R. (2004) Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators. Anticancer Research, 24, 409-415.
    • (2004) Anticancer Research , vol.24 , pp. 409-415
    • Brooks, T.1    Kennedy, D.2    Gruol, D.3    Ojima, I.4    Baer, M.5    Bernacki, R.6
  • 306
    • 0034954447 scopus 로고    scopus 로고
    • The use of a novel taxane-based P-glycoprotein inhibitors to identify mutations altering the protein's interaction with paclitaxel
    • Gruol, D., Bernd, J., Phippard, A., Ojima, I., and Bernacki, R. (2001) The use of a novel taxane-based P-glycoprotein inhibitors to identify mutations altering the protein's interaction with paclitaxel. Molecular Pharmacology, 60, 104-113.
    • (2001) Molecular Pharmacology , vol.60 , pp. 104-113
    • Gruol, D.1    Bernd, J.2    Phippard, A.3    Ojima, I.4    Bernacki, R.5
  • 310
    • 65249123159 scopus 로고    scopus 로고
    • Antivascular actions of microtubule-binding drugs
    • Schwartz, E. (2009) Antivascular actions of microtubule-binding drugs. Clinical Cancer Research, 15, 2594-2601.
    • (2009) Clinical Cancer Research , vol.15 , pp. 2594-2601
    • Schwartz, E.1
  • 312
    • 33751570159 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism in mice of IDN 5390 (13-)N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral C-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors
    • Frapolli, R., Marangon, E., Zaffaroni, M., Colombo, T., Falcioni, C., Bagnati, R., Simone, M., D'Incalci, M., Manzotti, C., Fontana, G., Morazzoni, P., and Zucchetti, M. (2006) Pharmacokinetics and metabolism in mice of IDN 5390 (13-)N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral C-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors. Drug Metabolism and Disposition, 34, 2028-2035.
    • (2006) Drug Metabolism and Disposition , vol.34 , pp. 2028-2035
    • Frapolli, R.1    Marangon, E.2    Zaffaroni, M.3    Colombo, T.4    Falcioni, C.5    Bagnati, R.6    Simone, M.7    D'Incalci, M.8    Manzotti, C.9    Fontana, G.10    Morazzoni, P.11    Zucchetti, M.12
  • 313
    • 0026686943 scopus 로고
    • Tuberculosis: commentary on a reemergent killer
    • Bloom, B.R. and Murray, C.J. (1992) Tuberculosis: commentary on a reemergent killer. Science, 257, 1055-1064.
    • (1992) Science , vol.257 , pp. 1055-1064
    • Bloom, B.R.1    Murray, C.J.2
  • 315
    • 0242693139 scopus 로고    scopus 로고
    • Assembly dynamics of the bacterial cell division protein FtsZ: poised at the edge of stability
    • Romberg, L. and Levin, P.A. (2003) Assembly dynamics of the bacterial cell division protein FtsZ: poised at the edge of stability. Annual Review of Microbiology, 57, 125-154.
    • (2003) Annual Review of Microbiology , vol.57 , pp. 125-154
    • Romberg, L.1    Levin, P.A.2
  • 316
    • 0026705484 scopus 로고
    • The essential bacterial cell-division protein FtsZ is a GTPase
    • DeBoer, P.C.R. and Rotherfield, L. (1992) The essential bacterial cell-division protein FtsZ is a GTPase. Nature, 359, 254-256.
    • (1992) Nature , vol.359 , pp. 254-256
    • DeBoer, P.C.R.1    Rotherfield, L.2
  • 317
    • 0029852223 scopus 로고    scopus 로고
    • Tubulin secondary structure analysis, limited proteolysis sites and homology to FtsZ
    • dePereda, J.M., Leynadier, D., Evangelio, J.A., Chacon, P., and Andreu, J.M. (1996) Tubulin secondary structure analysis, limited proteolysis sites and homology to FtsZ. Biochemistry, 35, 14203-14215.
    • (1996) Biochemistry , vol.35 , pp. 14203-14215
    • dePereda, J.M.1    Leynadier, D.2    Evangelio, J.A.3    Chacon, P.4    Andreu, J.M.5
  • 318


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