-
1
-
-
7144248725
-
Plant antitumor agents: I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
-
Wall, M.E., Wani, M.C., Cook, C.E., Palmer, C.E., and McPhail, A.T. (1966) Plant antitumor agents: I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. Journal of the American Chemical Society, 88, 3888-3894.
-
(1966)
Journal of the American Chemical Society
, vol.88
, pp. 3888-3894
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
Palmer, C.E.4
McPhail, A.T.5
-
2
-
-
0015211527
-
Plant antitumor agents: VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
-
Wani, M.C., Taylor, H.L., Wall, M.E., Coggan, P., and McPhail, A.T. (1971) Plant antitumor agents: VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. Journal of the American Chemical Society, 93, 2325-2327.
-
(1971)
Journal of the American Chemical Society
, vol.93
, pp. 2325-2327
-
-
Wani, M.C.1
Taylor, H.L.2
Wall, M.E.3
Coggan, P.4
McPhail, A.T.5
-
3
-
-
37049141680
-
Plant antitumour agents: alkaloids -synthesis of a pentacyclic camptothecin precursor
-
Wani, M.C., Kepler, J.A., Thompson, J.B., Wall, M.E., and Levine, S.G. (1970) Plant antitumour agents: alkaloids -synthesis of a pentacyclic camptothecin precursor. Journal of the Chemical Society. Chemical Communications, 404.
-
(1970)
Journal of the Chemical Society. Chemical Communications
, pp. 404
-
-
Wani, M.C.1
Kepler, J.A.2
Thompson, J.B.3
Wall, M.E.4
Levine, S.G.5
-
4
-
-
0017105425
-
Isolation and chemical characterization of antitumor agents from plants
-
Wall, M.E., Wani, M.C., and Taylor, H.L. (1976) Isolation and chemical characterization of antitumor agents from plants. Cancer Treatment Reports, 60, 1011-1014.
-
(1976)
Cancer Treatment Reports
, vol.60
, pp. 1011-1014
-
-
Wall, M.E.1
Wani, M.C.2
Taylor, H.L.3
-
5
-
-
0031754884
-
Tour de paclitaxel: biocatalysis for semisynthesis
-
Patel, R.N. (1998) Tour de paclitaxel: biocatalysis for semisynthesis. Annual Review of Microbiology, 98, 361-395.
-
(1998)
Annual Review of Microbiology
, vol.98
, pp. 361-395
-
-
Patel, R.N.1
-
6
-
-
0018188876
-
Cytologic evidence that taxol, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison
-
Fuchs, D.A. and Johnson, R.K. (1978) Cytologic evidence that taxol, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison. Cancer Treatment Reports, 62, 1219-1222.
-
(1978)
Cancer Treatment Reports
, vol.62
, pp. 1219-1222
-
-
Fuchs, D.A.1
Johnson, R.K.2
-
7
-
-
0018387446
-
Promotion of microtubule assembly in vitro by taxol
-
Horwitz, S.B., Fant, J., and Schiff, P.B. (1979) Promotion of microtubule assembly in vitro by taxol. Nature, 277, 665-667.
-
(1979)
Nature
, vol.277
, pp. 665-667
-
-
Horwitz, S.B.1
Fant, J.2
Schiff, P.B.3
-
8
-
-
1442285598
-
Personal recollections on the early development of taxol
-
Horwitz, S.B. (2004) Personal recollections on the early development of taxol. Journal of Natural Products, 67, 136-138.
-
(2004)
Journal of Natural Products
, vol.67
, pp. 136-138
-
-
Horwitz, S.B.1
-
9
-
-
0025742954
-
Government moves to increase taxol supply
-
Blume, E. (1991) Government moves to increase taxol supply. Journal of the National Cancer Institute, 83, 1054-1056.
-
(1991)
Journal of the National Cancer Institute
, vol.83
, pp. 1054-1056
-
-
Blume, E.1
-
10
-
-
0027430002
-
The taxol supply crisis: new NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents
-
Cragg, G.M., Schepartz, S.A., Suffness, M., and Grever, M.R. (1993) The taxol supply crisis: new NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents. Journal of Natural Products, 56, 1657-1668.
-
(1993)
Journal of Natural Products
, vol.56
, pp. 1657-1668
-
-
Cragg, G.M.1
Schepartz, S.A.2
Suffness, M.3
Grever, M.R.4
-
11
-
-
0019783912
-
Structural analysis and biochemical study of isolated products of the yew: Taxus baccata L. (Taxaceae)
-
Chauviére, G., Guénard, D., Picot, F., Sénilh, V., and Potier, P. (1981) Structural analysis and biochemical study of isolated products of the yew: Taxus baccata L. (Taxaceae). Comptes Rendus de l'Académie des Sciences. Série II, 293, 501-503.
-
(1981)
Comptes Rendus de l'Académie des Sciences. Série II
, vol.293
, pp. 501-503
-
-
Chauviére, G.1
Guénard, D.2
Picot, F.3
Sénilh, V.4
Potier, P.5
-
13
-
-
0026723301
-
Taxol: the first of the taxanes, an important new class of anti-cancer agents
-
Rowinsky, E.K., Onetto, N., Canetta, R.M., and Arbuck, S.G. (1992) Taxol: the first of the taxanes, an important new class of anti-cancer agents. Seminars in Oncology, 19, 646-662.
-
(1992)
Seminars in Oncology
, vol.19
, pp. 646-662
-
-
Rowinsky, E.K.1
Onetto, N.2
Canetta, R.M.3
Arbuck, S.G.4
-
14
-
-
0031040149
-
The development and clinical utility of the taxane class of anti-microtubule chemotherapy agents
-
Rowinsky, E.K. (1997) The development and clinical utility of the taxane class of anti-microtubule chemotherapy agents. Annual Review of Medicine, 48, 353-374.
-
(1997)
Annual Review of Medicine
, vol.48
, pp. 353-374
-
-
Rowinsky, E.K.1
-
15
-
-
80155147586
-
Natural taxanes: developments since 1828
-
Wang, Y.-F., Shi, Q.-W., Dong, M., Kiyota, H., Gu, Y.-C., and Cong, B. (2011) Natural taxanes: developments since 1828. Chemical Reviews, 11, 7652-7709.
-
(2011)
Chemical Reviews
, vol.11
, pp. 7652-7709
-
-
Wang, Y.-F.1
Shi, Q.-W.2
Dong, M.3
Kiyota, H.4
Gu, Y.-C.5
Cong, B.6
-
17
-
-
0034789998
-
Taxol: biosynthesis, molecular genetics and biotechnological applications
-
Jennewein, S. and Croteau, R. (2001) Taxol: biosynthesis, molecular genetics and biotechnological applications. Applied Microbiology and Biotechnology, 57, 13-19.
-
(2001)
Applied Microbiology and Biotechnology
, vol.57
, pp. 13-19
-
-
Jennewein, S.1
Croteau, R.2
-
18
-
-
0034680578
-
Studies on the biosynthesis of taxol: synthesis of taxa-4(20),11(12)-diene-2a, 5a-diol
-
Vazquez, A. and Williams, R.M. (2000) Studies on the biosynthesis of taxol: synthesis of taxa-4(20),11(12)-diene-2a, 5a-diol. The Journal of Organic Chemistry, 65, 7865-7869.
-
(2000)
The Journal of Organic Chemistry
, vol.65
, pp. 7865-7869
-
-
Vazquez, A.1
Williams, R.M.2
-
19
-
-
0023074211
-
Taxol and derivatives: a biogenetic hypothesis
-
Gueritte-Voegelein, F., Guenard, D., and Potier, P. (1987) Taxol and derivatives: a biogenetic hypothesis. Journal of Natural Products, 50, 9-18.
-
(1987)
Journal of Natural Products
, vol.50
, pp. 9-18
-
-
Gueritte-voegelein, F.1
Guenard, D.2
Potier, P.3
-
20
-
-
11944265206
-
Search and discovery of new antitumour compounds
-
Potier, P. (1992) Search and discovery of new antitumour compounds. Chemical Society Reviews, 21, 113-119.
-
(1992)
Chemical Society Reviews
, vol.21
, pp. 113-119
-
-
Potier, P.1
-
21
-
-
85127711105
-
Biosynthesis of Taxol
-
(M. Suffness), CRC Press, Boca Raton, FL
-
1: Science and Applications (ed. M. Suffness), CRC Press, Boca Raton, FL, pp. 191-208.
-
(1995)
1: Science and Applications
, pp. 191-208
-
-
Floss, H.G.1
Mocek, U.2
-
22
-
-
0000715988
-
Taxanes from Taxus yunnanensis
-
Zhang, Z. and Jia, Z. (1990) Taxanes from Taxus yunnanensis. Phytochemistry, 29, 3673-3675.
-
(1990)
Phytochemistry
, vol.29
, pp. 3673-3675
-
-
Zhang, Z.1
Jia, Z.2
-
23
-
-
0019422654
-
Antileukemic alkaloids from Taxus wallichiana Zucc
-
Miller, R.W., Powell, R.G., Smith, C.R., Jr., Arnold, E., and Clardy, J. (1981) Antileukemic alkaloids from Taxus wallichiana Zucc. The Journal of Organic Chemistry, 46, 1469-1474.
-
(1981)
The Journal of Organic Chemistry
, vol.46
, pp. 1469-1474
-
-
Miller, R.W.1
Powell, R.G.2
Smith, C.R.3
Arnold, E.4
Clardy, J.5
-
24
-
-
0032823015
-
Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana
-
Bala, S., Uniyal, G.C., Chattopadhyay, S.K., Tripathi, V., Sashidhara, K.V., Kulshrestha, M., Sharma, R.P., Jain, S.P., Kukreja, A.K., and Kumar, S. (1999) Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana. Journal of Chromatography. A, 858, 239-244.
-
(1999)
Journal of Chromatography. A
, vol.858
, pp. 239-244
-
-
Bala, S.1
Uniyal, G.C.2
Chattopadhyay, S.K.3
Tripathi, V.4
Sashidhara, K.V.5
Kulshrestha, M.6
Sharma, R.P.7
Jain, S.P.8
Kukreja, A.K.9
Kumar, S.10
-
25
-
-
0007694138
-
Hemisynthesis of new taxol analogs: investigation of their interaction with tubulin
-
Senilh, V., Guéritte, F., Guénard, D., Colin, M., and Potier, P. (1984) Hemisynthesis of new taxol analogs: investigation of their interaction with tubulin. Comptes Rendus de l'Académie des Sciences, Série II, 299, 1039-1043.
-
(1984)
Comptes Rendus de l'Académie des Sciences, Série II
, vol.299
, pp. 1039-1043
-
-
Senilh, V.1
Guéritte, F.2
Guénard, D.3
Colin, M.4
Potier, P.5
-
26
-
-
0023678710
-
A highly efficient, practical approach to natural taxol
-
Denis, J.-N., Greene, A.E., Guenard, D., Gueritte-Voegelein, F., Mangatal, L., and Potier, P. (1988) A highly efficient, practical approach to natural taxol. Journal of the American Chemical Society, 110, 5917-5919.
-
(1988)
Journal of the American Chemical Society
, vol.110
, pp. 5917-5919
-
-
Denis, J.-N.1
Greene, A.E.2
Guenard, D.3
Gueritte-voegelein, F.4
Mangatal, L.5
Potier, P.6
-
28
-
-
0025973097
-
Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-b-lactams through chiral ester enolate-imine cyclocondensation
-
Ojima, I., Habus, I., Zhao, M., Georg, G.I., and Jayasinghe, R. (1991) Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-b-lactams through chiral ester enolate-imine cyclocondensation. The Journal of Organic Chemistry, 56, 1681-1683.
-
(1991)
The Journal of Organic Chemistry
, vol.56
, pp. 1681-1683
-
-
Ojima, I.1
Habus, I.2
Zhao, M.3
Georg, G.I.4
Jayasinghe, R.5
-
29
-
-
0026686518
-
New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of b-lactam synthon method
-
Ojima, I., Habus, I., Zhao, M., Zucco, M., Park, Y.H., Sun, C.-M., and Brigaud, T. (1992) New and efficient approaches to the semisynthesis of taxol and its C-13 side chain analogs by means of b-lactam synthon method. Tetrahedron, 48, 6985-7012.
-
(1992)
Tetrahedron
, vol.48
, pp. 6985-7012
-
-
Ojima, I.1
Habus, I.2
Zhao, M.3
Zucco, M.4
Park, Y.H.5
Sun, C.-M.6
Brigaud, T.7
-
30
-
-
0028232538
-
Synthesis of taxol from baccatin III via an oxazoline intermediate
-
Kingston, D.G., Chaudhary, A.G., Gunatilaka, A.A.L., and Middleton, M.L. (1994) Synthesis of taxol from baccatin III via an oxazoline intermediate. Tetrahedron Letters, 35, 4486-4489.
-
(1994)
Tetrahedron Letters
, vol.35
, pp. 4486-4489
-
-
Kingston, D.G.1
Chaudhary, A.G.2
Gunatilaka, A.A.L.3
Middleton, M.L.4
-
31
-
-
0028302451
-
Expeditious semisynthesis of docetaxel using 2-trichloromethyl-1,3-oxazolidine as side-chain protection
-
Didier, E., Fouque, E., and Commerçon, A. (1994) Expeditious semisynthesis of docetaxel using 2-trichloromethyl-1,3-oxazolidine as side-chain protection. Tetrahedron Letters, 35, 3063-3064.
-
(1994)
Tetrahedron Letters
, vol.35
, pp. 3063-3064
-
-
Didier, E.1
Fouque, E.2
Commerçon, A.3
-
32
-
-
0028213554
-
2-Monosubstituted-1,3-oxazolidines as improved protective groups of N-Boc-phenylisoserine in docetaxel preparation
-
Didier, E., Fouque, E., Taillepied, I., and Commerçon, A. (1994) 2-Monosubstituted-1,3-oxazolidines as improved protective groups of N-Boc-phenylisoserine in docetaxel preparation. Tetrahedron Letters, 35, 2349-2352.
-
(1994)
Tetrahedron Letters
, vol.35
, pp. 2349-2352
-
-
Didier, E.1
Fouque, E.2
Taillepied, I.3
Commerçon, A.4
-
33
-
-
0032790361
-
A new semisynthesis of paclitaxel from baccatin III
-
Baloglu, E. and Kingston, D.G.I. (1999) A new semisynthesis of paclitaxel from baccatin III. Journal of Natural Products, 62, 1068-1071.
-
(1999)
Journal of Natural Products
, vol.62
, pp. 1068-1071
-
-
Baloglu, E.1
Kingston, D.G.I.2
-
34
-
-
0028213668
-
First total synthesis of taxol: 1. Functionalization of the B ring
-
Holton, R.A., Somoza, C., Kim, H.-B., Liang, F., Biediger, R.J., Boatman, P.D., Shindo, M., Smith, S.C., Kim, S., Nadizadeh, H., Suzuki, Y., Tao, C., Vu, P., Tang, S., Zhang, P., Murthi, K.K., Gentile, L.N., and Liu, J.H. (1994) First total synthesis of taxol: 1. Functionalization of the B ring. Journal of the American Chemical Society, 116, 1597-1598.
-
(1994)
Journal of the American Chemical Society
, vol.116
, pp. 1597-1598
-
-
Holton, R.A.1
Somoza, C.2
Kim, H.-B.3
Liang, F.4
Biediger, R.J.5
Boatman, P.D.6
Shindo, M.7
Smith, S.C.8
Kim, S.9
Nadizadeh, H.10
Suzuki, Y.11
Tao, C.12
Vu, P.13
Tang, S.14
Zhang, P.15
Murthi, K.K.16
Gentile, L.N.17
Liu, J.H.18
-
35
-
-
0028353983
-
First total synthesis of taxol: 2. Completion of the C and D rings
-
Holton, R.A., Somoza, C., Kim, H-Baik, Liang, F., Biediger, R.J., Boatman, P.D., Shindo, M., Smith, S.C., Kim, S., Nadizadeh, H., Suzuki, Y., Tao, C., Vu, P., Tang, S., Zhang, P., Murthi, K.K., Gentile, L.N., Liu, J.H. (1994) First total synthesis of taxol: 2. Completion of the C and D rings. Journal of the American Chemical Society, 116, 1599-1600.
-
(1994)
Journal of the American Chemical Society
, vol.116
, pp. 1599-1600
-
-
Holton, R.A.1
Somoza, C.2
Kim, H.-B.3
Liang, F.4
Biediger, R.J.5
Boatman, P.D.6
Shindo, M.7
Smith, S.C.8
Kim, S.9
Nadizadeh, H.10
Suzuki, Y.11
Tao, C.12
Vu, P.13
Tang, S.14
Zhang, P.15
Murthi, K.K.16
Gentile, L.N.17
Liu, J.H.18
-
36
-
-
11044223276
-
Total synthesis of baccatin III and taxol
-
Danishefsky, S.J., Masters, J.J., Young, W.B., Link, J.T., Snyder, L.B., Magee, T.V., Jung, J.K., Isaacs, R.C.A., Bornmann, W.G., Alaimo, C.A., Coburn, C.A., and Dii Grandi, M.J. (1996) Total synthesis of baccatin III and taxol. Journal of the American Chemical Society, 118, 2843-2859.
-
(1996)
Journal of the American Chemical Society
, vol.118
, pp. 2843-2859
-
-
Danishefsky, S.J.1
Masters, J.J.2
Young, W.B.3
Link, J.T.4
Snyder, L.B.5
Magee, T.V.6
Jung, J.K.7
Isaacs, R.C.A.8
Bornmann, W.G.9
Alaimo, C.A.10
Coburn, C.A.11
Dii Grandi, M.J.12
-
37
-
-
0028012837
-
Total synthesis of taxol
-
Nicolaou, K.C., Yang, Z., Liu, J.J., Ueno, H., Nantermet, P.G., Guy, R.K., Claiborne, C.F., Renaud, J., Couladouros, E.A., Paulvannan, K., and Sorensen, E.J. (1994) Total synthesis of taxol. Nature, 367, 630-634.
-
(1994)
Nature
, vol.367
, pp. 630-634
-
-
Nicolaou, K.C.1
Yang, Z.2
Liu, J.J.3
Ueno, H.4
Nantermet, P.G.5
Guy, R.K.6
Claiborne, C.F.7
Renaud, J.8
Couladouros, E.A.9
Paulvannan, K.10
Sorensen, E.J.11
-
38
-
-
0032539249
-
Enantioselective total synthesis of (-)taxol
-
Morihira, K., Hara, R., Kawahara, H., Nishimori, T., Nakamura, N., Kusama, H., and Kuwajima, I. (1998) Enantioselective total synthesis of (-)taxol. Journal of the American Chemical Society, 120, 12980-12981.
-
(1998)
Journal of the American Chemical Society
, vol.120
, pp. 12980-12981
-
-
Morihira, K.1
Hara, R.2
Kawahara, H.3
Nishimori, T.4
Nakamura, N.5
Kusama, H.6
Kuwajima, I.7
-
39
-
-
0030936927
-
The pinene path to taxanes: 6. A concise stereocontrolled synthesis of taxol
-
Wender, P.A., Badham, N.F., Conway, S.P., Floreancig, P.E., Glass, T.E., Houze, J.B., Krauss, N.E., Lee, D., Marquess, D.G., McGrane, P.L., Meng, W., Natchus, M.G., Shuker, A.J., Sutton, J.C., and Taylor, R.E. (1997) The pinene path to taxanes: 6. A concise stereocontrolled synthesis of taxol. Journal of the American Chemical Society, 119, 2757-2758.
-
(1997)
Journal of the American Chemical Society
, vol.119
, pp. 2757-2758
-
-
Wender, P.A.1
Badham, N.F.2
Conway, S.P.3
Floreancig, P.E.4
Glass, T.E.5
Houze, J.B.6
Krauss, N.E.7
Lee, D.8
Marquess, D.G.9
McGrane, P.L.10
Meng, W.11
Natchus, M.G.12
Shuker, A.J.13
Sutton, J.C.14
Taylor, R.E.15
-
40
-
-
0032959568
-
Asymmetric total synthesis of taxol
-
Mukaiyama, T., Shiina, I., Iwadare, H., Saitoh, M., Nishimura, T., Ohkawa, N., Sakoh, H., Nishimura, T., Tani, Y.-I., Hasegawa, M., Yamada, K., and Saitoh, K. (1999) Asymmetric total synthesis of taxol. Chemistry -A European Journal, 5, 121-161.
-
(1999)
Chemistry -A European Journal
, vol.5
, pp. 121-161
-
-
Mukaiyama, T.1
Shiina, I.2
Iwadare, H.3
Saitoh, M.4
Nishimura, T.5
Ohkawa, N.6
Sakoh, H.7
Nishimura, T.8
Tani, Y.-I.9
Hasegawa, M.10
Yamada, K.11
Saitoh, K.12
-
41
-
-
0028810338
-
Total synthesis of taxol: 1. Retrosynthesis, degradation and reconstitution
-
Nicolaou, K.C., Nantermet, P.G., Ueno, H., Guy, R.K., and Sorensen, E.J. (1995) Total synthesis of taxol: 1. Retrosynthesis, degradation and reconstitution. Journal of the American Chemical Society, 117, 624-633.
-
(1995)
Journal of the American Chemical Society
, vol.117
, pp. 624-633
-
-
Nicolaou, K.C.1
Nantermet, P.G.2
Ueno, H.3
Guy, R.K.4
Sorensen, E.J.5
-
42
-
-
0028792481
-
Total synthesis of taxol: 2. Construction of the A and C ring intermediates and initial attempts to construct the ABC ring system
-
Nicolaou, K.C., Liu, J.-J., Yang, Z., Ueno, H., Guy, R.K., Sorensen, E.J., Claiborne, C.F., Guy, R.K., Hwang, C.-K., Nakada, M., and Nantermet, P.G. (1995) Total synthesis of taxol: 2. Construction of the A and C ring intermediates and initial attempts to construct the ABC ring system. Journal of the American Chemical Society, 117, 634-644.
-
(1995)
Journal of the American Chemical Society
, vol.117
, pp. 634-644
-
-
Nicolaou, K.C.1
Liu, J.-J.2
Yang, Z.3
Ueno, H.4
Guy, R.K.5
Sorensen, E.J.6
Claiborne, C.F.7
Guy, R.K.8
Hwang, C.-K.9
Nakada, M.10
Nantermet, P.G.11
-
43
-
-
0028849334
-
Total synthesis of taxol: 3. Formation of taxol's ABC ring skeleton
-
Nicolaou, K.C., Yang, Z., Liu, J.-J., Nantermet, P.G., Claiborne, C.F., Guy, R.K., and Shibayama., K. (1995) Total synthesis of taxol: 3. Formation of taxol's ABC ring skeleton. Journal of the American Chemical Society, 117, 645-652.
-
(1995)
Journal of the American Chemical Society
, vol.117
, pp. 645-652
-
-
Nicolaou, K.C.1
Yang, Z.2
Liu, J.-J.3
Nantermet, P.G.4
Claiborne, C.F.5
Guy, R.K.6
Shibayama, K.7
-
44
-
-
0028868994
-
Total synthesis of taxol: 4. The final stages and completion of the synthesis
-
Nicolaou, K.C., Ueno, H., Liu, J.-J., Nantermet, P.G., Yang, Z., Renaud, J., Paulvannan, K., and Chadha, R. (1995) Total synthesis of taxol: 4. The final stages and completion of the synthesis. Journal of the American Chemical Society, 117, 653-659.
-
(1995)
Journal of the American Chemical Society
, vol.117
, pp. 653-659
-
-
Nicolaou, K.C.1
Ueno, H.2
Liu, J.-J.3
Nantermet, P.G.4
Yang, Z.5
Renaud, J.6
Paulvannan, K.7
Chadha, R.8
-
45
-
-
0030889501
-
The pinene path to taxanes: 5. Stereocontrolled synthesis of a versatile taxane precursor
-
Wender, P.A., Badham, N.F., Conway, S.P., Floreancig, P.E., Glass, T.E., Gränicher, C., Houze, J.B., Jänichen, J., Lee, D., Marquess, D.G., McGrane, P.L., Meng, W., Mucciaro, T.P., Mühlebach, M., Natchus, M.G., Paulsen, H., Rawlins, D.B., Satkofsky, J., Shuker, A.J., Sutton, J.C., Taylor, R.E., and Tomooka, K. (1997) The pinene path to taxanes: 5. Stereocontrolled synthesis of a versatile taxane precursor. Journal of the American Chemical Society, 119, 2755-2756.
-
(1997)
Journal of the American Chemical Society
, vol.119
, pp. 2755-2756
-
-
Wender, P.A.1
Badham, N.F.2
Conway, S.P.3
Floreancig, P.E.4
Glass, T.E.5
Gränicher, C.6
Houze, J.B.7
Jänichen, J.8
Lee, D.9
Marquess, D.G.10
McGrane, P.L.11
Meng, W.12
Mucciaro, T.P.13
Mühlebach, M.14
Natchus, M.G.15
Paulsen, H.16
Rawlins, D.B.17
Satkofsky, J.18
Shuker, A.J.19
Sutton, J.C.20
Taylor, R.E.21
Tomooka, K.22
more..
-
46
-
-
0034716749
-
Enantioselective total synthesis of taxol
-
Kusama, H., Hara, R., Kawahara, S., Nishimori, T., Kashima, H., Nakamura, N., Morihira, K., and Kuwajima, I. (2000) Enantioselective total synthesis of taxol. Journal of the American Chemical Society, 122, 3811-3820.
-
(2000)
Journal of the American Chemical Society
, vol.122
, pp. 3811-3820
-
-
Kusama, H.1
Hara, R.2
Kawahara, S.3
Nishimori, T.4
Kashima, H.5
Nakamura, N.6
Morihira, K.7
Kuwajima, I.8
-
47
-
-
0026680655
-
Effects of genetic, epigenetic and environmental factors on taxol content in Taxus brevifolia and related species
-
Wheeler, N.C., Jech, K., Masters, S., Brobst, S.W., Alvarado, A.B., Hoover, A.J., and Snader, K.M. (1992) Effects of genetic, epigenetic and environmental factors on taxol content in Taxus brevifolia and related species. Journal of Natural Products, 55, 432-440.
-
(1992)
Journal of Natural Products
, vol.55
, pp. 432-440
-
-
Wheeler, N.C.1
Jech, K.2
Masters, S.3
Brobst, S.W.4
Alvarado, A.B.5
Hoover, A.J.6
Snader, K.M.7
-
49
-
-
84926449688
-
Greener Synthetic Pathways Award: Bristol-Myers Squibb Company: Development of a Green Synthesis for TAXOL Manufacture via Plant Cell Fermentation and Extraction
-
Agency, U.E.P. (2004) Greener Synthetic Pathways Award: Bristol-Myers Squibb Company: Development of a Green Synthesis for TAXOL Manufacture via Plant Cell Fermentation and Extraction, www.epa.gov/greenchemistry/pubs/pgcc/winners/gspa04.html.
-
(2004)
-
-
Agency, U.E.P.1
-
50
-
-
9144225346
-
Production of biologically active taxoids by a callus culture of Taxus cuspidata
-
Bai, J., Kitabatake, M., Toyoizumi, M., Fu, L., Zhang, S., Dai, S., Sakai, J., Hirose, K., Yamori, T., Tomida, A., Tsuruo, T., and Ando, M. (2004) Production of biologically active taxoids by a callus culture of Taxus cuspidata. Journal of Natural Products, 67, 58-63.
-
(2004)
Journal of Natural Products
, vol.67
, pp. 58-63
-
-
Bai, J.1
Kitabatake, M.2
Toyoizumi, M.3
Fu, L.4
Zhang, S.5
Dai, S.6
Sakai, J.7
Hirose, K.8
Yamori, T.9
Tomida, A.10
Tsuruo, T.11
Ando, M.12
-
51
-
-
0028221561
-
New bioactive taxoids from cell cultures of Taxus baccata
-
Ma, W., Park, G.L., Gomez, G.A., Neider, M.H., Adams, T.L., Aynsley, J.S., Sahai, O.P., Smith, R.J., Stahlhut, R.W., and Hylands, P.J. (1994) New bioactive taxoids from cell cultures of Taxus baccata. Journal of Natural Products, 57, 116-122.
-
(1994)
Journal of Natural Products
, vol.57
, pp. 116-122
-
-
Ma, W.1
Park, G.L.2
Gomez, G.A.3
Neider, M.H.4
Adams, T.L.5
Aynsley, J.S.6
Sahai, O.P.7
Smith, R.J.8
Stahlhut, R.W.9
Hylands, P.J.10
-
52
-
-
0027033799
-
Cell culture of Taxus as a source of the antineoplastic drug taxol and related taxanes
-
Fett-Neto, A.G., DiCosmo, F., Reynolds, W.F., and Sakata, K. (1992) Cell culture of Taxus as a source of the antineoplastic drug taxol and related taxanes. Bio/ Technology, 10, 1572-1575.
-
(1992)
Bio/ Technology
, vol.10
, pp. 1572-1575
-
-
Fett-neto, A.G.1
DiCosmo, F.2
Reynolds, W.F.3
Sakata, K.4
-
53
-
-
14744288106
-
Taxol: out of the woods
-
Edgington, S.M. (1991) Taxol: out of the woods. Bio/Technology, 9, 933-938.
-
(1991)
Bio/Technology
, vol.9
, pp. 933-938
-
-
Edgington, S.M.1
-
54
-
-
0030059628
-
Taxol from Pestalotiopsis microspora, an endophytic fungus of Taxus wallachiana
-
Strobel, G., Yang, X., Sears, J., Kramer, R., Sidhu, R.S., and Hess, W.M. (1996) Taxol from Pestalotiopsis microspora, an endophytic fungus of Taxus wallachiana. Microbiology (Reading, England), 142, 435-440.
-
(1996)
Microbiology (Reading, England)
, vol.142
, pp. 435-440
-
-
Strobel, G.1
Yang, X.2
Sears, J.3
Kramer, R.4
Sidhu, R.S.5
Hess, W.M.6
-
55
-
-
0027270462
-
Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew
-
Stierle, A., Strobel, G., and Stierle, D. (1993) Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew. Science, 260, 214-216.
-
(1993)
Science
, vol.260
, pp. 214-216
-
-
Stierle, A.1
Strobel, G.2
Stierle, D.3
-
56
-
-
0034672382
-
Taxol from Tubercularia sp. strain TF5, an endophytic fungus of Taxus mairei
-
Wang, J., Li, G., Lu, H., Zheng, Z., Huang, Y., and Su, W. (2000) Taxol from Tubercularia sp. strain TF5, an endophytic fungus of Taxus mairei. FEMS Microbiology Letters, 193, 249-253.
-
(2000)
FEMS Microbiology Letters
, vol.193
, pp. 249-253
-
-
Wang, J.1
Li, G.2
Lu, H.3
Zheng, Z.4
Huang, Y.5
Su, W.6
-
57
-
-
0029824617
-
Endophytic taxol producing fungi from bald cypress Taxodium distichum
-
Li, J.Y., Strobel, G., Sidhu, R., Hess, W.M., and Ford, E.J. (1996) Endophytic taxol producing fungi from bald cypress Taxodium distichum. Microbiology (Reading, England), 142, 2223-2226.
-
(1996)
Microbiology (Reading, England)
, vol.142
, pp. 2223-2226
-
-
Li, J.Y.1
Strobel, G.2
Sidhu, R.3
Hess, W.M.4
Ford, E.J.5
-
58
-
-
0025326680
-
Hypersensitivity reactions from taxol
-
Weiss, R., Donehower, R.C., and Wiernik, P.H. (1990) Hypersensitivity reactions from taxol. Journal of Clinical Oncology, 8, 1263-1268.
-
(1990)
Journal of Clinical Oncology
, vol.8
, pp. 1263-1268
-
-
Weiss, R.1
Donehower, R.C.2
Wiernik, P.H.3
-
59
-
-
0027228024
-
Clinical toxicities encountered with taxol
-
Rowinsky, E.K., Eisenhauer, E.A., and Chaudhry, V. (1993) Clinical toxicities encountered with taxol. Seminars in Oncology, 20 (Suppl. 3), 1-15.
-
(1993)
Seminars in Oncology
, vol.20
, pp. 1-15
-
-
Rowinsky, E.K.1
Eisenhauer, E.A.2
Chaudhry, V.3
-
60
-
-
0025850566
-
Sequences of taxol and cisplatin: a phase I and pharmacologic study
-
Rowinsky, E.K., Gilbert, M., and McGuire, W.P. (1991) Sequences of taxol and cisplatin: a phase I and pharmacologic study. Journal of Clinical Oncology, 9, 1692-1703.
-
(1991)
Journal of Clinical Oncology
, vol.9
, pp. 1692-1703
-
-
Rowinsky, E.K.1
Gilbert, M.2
McGuire, W.P.3
-
61
-
-
0030054309
-
Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
-
McGuire, W.P., Hoskins, W.J., and Brady, M.F. (1996) Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer. New England Journal of Medicine, 334, 1-6.
-
(1996)
New England Journal of Medicine
, vol.334
, pp. 1-6
-
-
McGuire, W.P.1
Hoskins, W.J.2
Brady, M.F.3
-
63
-
-
0029063397
-
Structure of tubulin at 6.5 A and location of the taxol-binding site
-
Nogales, E., Wolf, S., Khan, I., Luduena, R., and Downing, K. (1995) Structure of tubulin at 6.5 A and location of the taxol-binding site. Nature, 375, 424-427.
-
(1995)
Nature
, vol.375
, pp. 424-427
-
-
Nogales, E.1
Wolf, S.2
Khan, I.3
Luduena, R.4
Downing, K.5
-
64
-
-
0026682713
-
Low resolution structure of microtubules in solution: synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in comparison with glycerol and MAP-induced microtubules
-
Andreu, J.M., Bordas, J., Diaz, J.F., deAncos, J.G., Gil, R., Medrano, F.J., Nogales, E., Pantos, E., and Towns-Andrews, E. (1992) Low resolution structure of microtubules in solution: synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in comparison with glycerol and MAP-induced microtubules. Journal of Molecular Biology, 226, 169-184.
-
(1992)
Journal of Molecular Biology
, vol.226
, pp. 169-184
-
-
Andreu, J.M.1
Bordas, J.2
Diaz, J.F.3
deAncos, J.G.4
Gil, R.5
Medrano, F.J.6
Nogales, E.7
Pantos, E.8
Towns-andrews, E.9
-
65
-
-
0032509226
-
Changes in microtubule protofilament number induced by taxol binding to an easily accessible site
-
Diaz, J., Valpuesta, J., Chacon, P., Diakun, G., and Andreu, J. (1998) Changes in microtubule protofilament number induced by taxol binding to an easily accessible site. The Journal of Biological Chemistry, 272, 33803-33810.
-
(1998)
The Journal of Biological Chemistry
, vol.272
, pp. 33803-33810
-
-
Diaz, J.1
Valpuesta, J.2
Chacon, P.3
Diakun, G.4
Andreu, J.5
-
68
-
-
0027494879
-
Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients
-
Huizing, M.T., Keung, A.C., Rosing, H., van derKuij, V., tenBokkel Huinink, W.W., Mandjes, I.M., Dubbelman, A.C., Pinedo, H.M., and Beijen, J.H. (1993) Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients. Journal of Clinical Oncology, 11, 2127-2135.
-
(1993)
Journal of Clinical Oncology
, vol.11
, pp. 2127-2135
-
-
Huizing, M.T.1
Keung, A.C.2
Rosing, H.3
van derKuij, V.4
tenBokkel Huinink, W.W.5
Mandjes, I.M.6
Dubbelman, A.C.7
Pinedo, H.M.8
Beijen, J.H.9
-
69
-
-
0032006059
-
Microtubules and actin filaments: dynamic targets for cancer chemotherapy
-
Jordan, M. and Wilson, L. (1998) Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Current Opinion in Cell Biology, 10, 123-130.
-
(1998)
Current Opinion in Cell Biology
, vol.10
, pp. 123-130
-
-
Jordan, M.1
Wilson, L.2
-
70
-
-
0028070358
-
Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase
-
Long, B. and Fairchild, C. (1994) Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase. Cancer Research, 54, 4355-4361.
-
(1994)
Cancer Research
, vol.54
, pp. 4355-4361
-
-
Long, B.1
Fairchild, C.2
-
71
-
-
0028241451
-
Cytotoxicity of the anti-cancer agents cisplatin and taxol during cell proliferation and the cell cycle
-
Donaldson, K., Goolsby, G., and Wahl, A. (1994) Cytotoxicity of the anti-cancer agents cisplatin and taxol during cell proliferation and the cell cycle. International Journal of Cancer, 57, 847-855.
-
(1994)
International Journal of Cancer
, vol.57
, pp. 847-855
-
-
Donaldson, K.1
Goolsby, G.2
Wahl, A.3
-
72
-
-
0030691967
-
Coupling cell division and cell death to microtubule dynamics
-
Sorger, P., Dobles, M., Tournebize, R., and Hyman, A. (1997) Coupling cell division and cell death to microtubule dynamics. Current Opinion in Cell Biology, 9, 807-814.
-
(1997)
Current Opinion in Cell Biology
, vol.9
, pp. 807-814
-
-
Sorger, P.1
Dobles, M.2
Tournebize, R.3
Hyman, A.4
-
73
-
-
0036184739
-
Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460
-
Huisman, C., Ferreira, C., Broker, L., Rodriguez, J., Smit, E., Postmus, P., Kruyt, F., and Giaccone, G. (2002) Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460. Clinical Cancer Research, 8, 596-606.
-
(2002)
Clinical Cancer Research
, vol.8
, pp. 596-606
-
-
Huisman, C.1
Ferreira, C.2
Broker, L.3
Rodriguez, J.4
Smit, E.5
Postmus, P.6
Kruyt, F.7
Giaccone, G.8
-
74
-
-
0033155995
-
A crucial role of caspase 3 and caspase 8 in paclitaxel-induced apoptosis
-
Oyaizu, H., Adachi, Y., Taketani, S., Tokunaga, R., Fukuhara, S., and Ikehara, S. (1999) A crucial role of caspase 3 and caspase 8 in paclitaxel-induced apoptosis. Molecular Cell Biology Research Communications, 2, 36-41.
-
(1999)
Molecular Cell Biology Research Communications
, vol.2
, pp. 36-41
-
-
Oyaizu, H.1
Adachi, Y.2
Taketani, S.3
Tokunaga, R.4
Fukuhara, S.5
Ikehara, S.6
-
75
-
-
70349974226
-
Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules
-
Mielgo, A., Torres, V., Clair, K., Barbero, S., and Stupack, D. (2009) Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules. Oncogene, 28, 3551-3562.
-
(2009)
Oncogene
, vol.28
, pp. 3551-3562
-
-
Mielgo, A.1
Torres, V.2
Clair, K.3
Barbero, S.4
Stupack, D.5
-
76
-
-
10944257440
-
Taxol induces caspase 10-dependent apoptosis
-
Park, S.-J., Wu, C.-H., Gordon, J., Zhong, X., Emami, A., and Safa, A. (2004) Taxol induces caspase 10-dependent apoptosis. The Journal of Biological Chemistry, 279, 51057-51067.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 51057-51067
-
-
Park, S.-J.1
Wu, C.-H.2
Gordon, J.3
Zhong, X.4
Emami, A.5
Safa, A.6
-
77
-
-
0001554639
-
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells
-
Shtil, A., Madlekar, S., Yu, R., Walter, R., Hagen, K., Tan, T., Roninson, I., and Kong, A. (1999) Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells. Oncogene, 18, 377-384.
-
(1999)
Oncogene
, vol.18
, pp. 377-384
-
-
Shtil, A.1
Madlekar, S.2
Yu, R.3
Walter, R.4
Hagen, K.5
Tan, T.6
Roninson, I.7
Kong, A.8
-
78
-
-
0034685876
-
Microtubule-interfering agents stimulate the transcription of cyclooxygenase: 2. Evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways
-
Subbaramaiah, K., Hart, J., Norton, L., and Dannenberg, A. (2000) Microtubule-interfering agents stimulate the transcription of cyclooxygenase: 2. Evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways. The Journal of Biological Chemistry, 275, 14838-14845.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 14838-14845
-
-
Subbaramaiah, K.1
Hart, J.2
Norton, L.3
Dannenberg, A.4
-
79
-
-
0032883001
-
Molecular effects of paclitaxel: myths and reality (a critical review)
-
Blagosklonny, M. and Fojo, T. (1999) Molecular effects of paclitaxel: myths and reality (a critical review). International Journal of Cancer, 83, 151-156.
-
(1999)
International Journal of Cancer
, vol.83
, pp. 151-156
-
-
Blagosklonny, M.1
Fojo, T.2
-
80
-
-
0029964257
-
Taxol induces Bcl-2 phosphorylation and death of prostate cancer cells
-
Haldar, S., Chintapalli, J., and Croce, C. (1996) Taxol induces Bcl-2 phosphorylation and death of prostate cancer cells. Cancer Research, 56, 1253-1255.
-
(1996)
Cancer Research
, vol.56
, pp. 1253-1255
-
-
Haldar, S.1
Chintapalli, J.2
Croce, C.3
-
81
-
-
0031035693
-
Bcl2 is the guardian of microtubule integrity
-
Haldar, S., Basu, A., and Croce, C. (1997) Bcl2 is the guardian of microtubule integrity. Cancer Research, 57, 229-233.
-
(1997)
Cancer Research
, vol.57
, pp. 229-233
-
-
Haldar, S.1
Basu, A.2
Croce, C.3
-
82
-
-
0031036307
-
Raf1/bcl2 phosphorylation: a step from microtubule damage to cell death
-
Blagosklonny, M., Giannakakou, P., El-Deiry, W., Kingston, D., Higgs, P., Neckers, L., and Fojo, T. (1997) Raf1/bcl2 phosphorylation: a step from microtubule damage to cell death. Cancer Research, 57, 130-135.
-
(1997)
Cancer Research
, vol.57
, pp. 130-135
-
-
Blagosklonny, M.1
Giannakakou, P.2
El-deiry, W.3
Kingston, D.4
Higgs, P.5
Neckers, L.6
Fojo, T.7
-
83
-
-
0030615086
-
Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human AML HL-60 cells
-
Ibrado, A., Liu, L., and Bhalla, K. (1997) Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human AML HL-60 cells. Cancer Research, 57, 1109-1115.
-
(1997)
Cancer Research
, vol.57
, pp. 1109-1115
-
-
Ibrado, A.1
Liu, L.2
Bhalla, K.3
-
84
-
-
1242272838
-
Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells
-
Chun, E. and Lee, K.-Y. (2004) Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells. Biochemical and Biophysical Research Communications, 315, 771-779.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.315
, pp. 771-779
-
-
Chun, E.1
Lee, K.-Y.2
-
85
-
-
0031687587
-
Bcl-2 overexpression is associated with resistance to paclitaxel, but not gemcitabine, in multiple myeloma cells
-
Gazitt, Y., Rothenberg, M., Hilsenback, S., Fey, V., Thomas, C., and Montegomrey, W. (1998) Bcl-2 overexpression is associated with resistance to paclitaxel, but not gemcitabine, in multiple myeloma cells. International Journal of Oncology, 13, 839-848.
-
(1998)
International Journal of Oncology
, vol.13
, pp. 839-848
-
-
Gazitt, Y.1
Rothenberg, M.2
Hilsenback, S.3
Fey, V.4
Thomas, C.5
Montegomrey, W.6
-
86
-
-
0033616709
-
Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis
-
Srivastava, R., Mi, Q.-S., Hardwick, J., and Longo, D. (1999) Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 96, 3775-3780.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 3775-3780
-
-
Srivastava, R.1
Mi, Q.-S.2
Hardwick, J.3
Longo, D.4
-
87
-
-
33646417913
-
Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index
-
Callagy, G., Pharoah, P., and Pinder, S. (2006) Bcl-2 is a prognostic marker in breast cancer independently of the Nottingham Prognostic Index. Clinical Cancer Research, 12, 2468-2475.
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 2468-2475
-
-
Callagy, G.1
Pharoah, P.2
Pinder, S.3
-
88
-
-
33750723137
-
Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy
-
Yoshino, T., Shiina, H., and Urakami, S. (2006) Bcl-2 expression as a predictive marker of hormone-refractory prostate cancer treated with taxane-based chemotherapy. Clinical Cancer Research, 12, 6116-6125.
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 6116-6125
-
-
Yoshino, T.1
Shiina, H.2
Urakami, S.3
-
89
-
-
18544367200
-
Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel
-
Mabuchi, S., Ohmichi, M., Kimura, A., Hisamoto, K., Hayakawa, J., Nishio, Y., Adachi, K., Takahashi, K., Arimoto-Ishida, E., Nakatsuji, Y., Tasaka, K., and Murata, Y. (2002) Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel. The Journal of Biological Chemistry, 277, 33490-33500.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, pp. 33490-33500
-
-
Mabuchi, S.1
Ohmichi, M.2
Kimura, A.3
Hisamoto, K.4
Hayakawa, J.5
Nishio, Y.6
Adachi, K.7
Takahashi, K.8
Arimoto-ishida, E.9
Nakatsuji, Y.10
Tasaka, K.11
Murata, Y.12
-
90
-
-
3042645219
-
Molecular mechanisms of the effects of low concentrations of taxol in anaplastic thyroid cancer cells
-
Pushkarev, V., Starenki, D., Saenko, V., Namba, H., Kurebayashi, J., Tronko, M., and Yamashita, S. (2004) Molecular mechanisms of the effects of low concentrations of taxol in anaplastic thyroid cancer cells. Endocrinology, 145, 3143-3152.
-
(2004)
Endocrinology
, vol.145
, pp. 3143-3152
-
-
Pushkarev, V.1
Starenki, D.2
Saenko, V.3
Namba, H.4
Kurebayashi, J.5
Tronko, M.6
Yamashita, S.7
-
91
-
-
15644381250
-
Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of constitutively active GTP binding protein Rac1
-
Maudrell, K., Antonsson, B., Magnenat, E., Camps, M., Muda, M., Chabert, C., Gillerron, C., Boschert, U., Vial-Knecht, E., Martinou, J.-C., and Arkinstall, S. (1997) Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of constitutively active GTP binding protein Rac1. The Journal of Biological Chemistry, 272, 25238-25242.
-
(1997)
The Journal of Biological Chemistry
, vol.272
, pp. 25238-25242
-
-
Maudrell, K.1
Antonsson, B.2
Magnenat, E.3
Camps, M.4
Muda, M.5
Chabert, C.6
Gillerron, C.7
Boschert, U.8
Vial-knecht, E.9
Martinou, J.-C.10
Arkinstall, S.11
-
92
-
-
0035136965
-
Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells
-
Shiah, S., Chuang, S., and Kuo, M. (2001) Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells. Molecular Pharmacology, 59, 254-262.
-
(2001)
Molecular Pharmacology
, vol.59
, pp. 254-262
-
-
Shiah, S.1
Chuang, S.2
Kuo, M.3
-
93
-
-
0029913172
-
Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway
-
Blagosklonny, M., Schulte, T., Nguyen, P., Trepel, J., and Neckers, L. (1996) Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway. Cancer Research, 56, 1851-1854.
-
(1996)
Cancer Research
, vol.56
, pp. 1851-1854
-
-
Blagosklonny, M.1
Schulte, T.2
Nguyen, P.3
Trepel, J.4
Neckers, L.5
-
94
-
-
0033542382
-
Serine protease inhibitor TPCK prevents taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells
-
Huang, Y., Sheikh, M., Fornance, A., and Holbrook, N. (1999) Serine protease inhibitor TPCK prevents taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells. Oncogene, 18, 3431-3439.
-
(1999)
Oncogene
, vol.18
, pp. 3431-3439
-
-
Huang, Y.1
Sheikh, M.2
Fornance, A.3
Holbrook, N.4
-
95
-
-
70450257737
-
The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts
-
Ahn, J.-H., Eum, K.-H., and Lee, M. (2009) The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts. Molecular and Cellular Biochemistry, 332, 189-197.
-
(2009)
Molecular and Cellular Biochemistry
, vol.332
, pp. 189-197
-
-
Ahn, J.-H.1
Eum, K.-H.2
Lee, M.3
-
96
-
-
0035377357
-
Paclitaxel induces prolonged activation of the Ras/ MEK/ERK pathway independently of activating the programmed cell death machinery
-
Okano, J.-I. and Rustgi, A. (2001) Paclitaxel induces prolonged activation of the Ras/ MEK/ERK pathway independently of activating the programmed cell death machinery. The Journal of Biological Chemistry, 276, 19555-19564.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 19555-19564
-
-
Okano, J.-I.1
Rustgi, A.2
-
97
-
-
70149101801
-
Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77
-
Ferlini, C., Cicchillitti, L., Raspaglio, G., Bartollino, S., Cimitan, S., Bertucci, C., Mozzetti, S., Gallo, D., Persico, M., Fattorusso, C., Campiani, G., and Scambia, G. (2009) Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77. Cancer Research, 69, 6906-6914.
-
(2009)
Cancer Research
, vol.69
, pp. 6906-6914
-
-
Ferlini, C.1
Cicchillitti, L.2
Raspaglio, G.3
Bartollino, S.4
Cimitan, S.5
Bertucci, C.6
Mozzetti, S.7
Gallo, D.8
Persico, M.9
Fattorusso, C.10
Campiani, G.11
Scambia, G.12
-
98
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakacs, G., Paterson, J., Ludwig, J., Booth-Genthe, C., and Gottesman, M. (2006) Targeting multidrug resistance in cancer. Nature Reviews. Drug Discovery, 5, 219-234.
-
(2006)
Nature Reviews. Drug Discovery
, vol.5
, pp. 219-234
-
-
Szakacs, G.1
Paterson, J.2
Ludwig, J.3
Booth-genthe, C.4
Gottesman, M.5
-
99
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman, M. and Pastan, I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annual Review of Biochemistry, 62, 385-427.
-
(1993)
Annual Review of Biochemistry
, vol.62
, pp. 385-427
-
-
Gottesman, M.1
Pastan, I.2
-
100
-
-
0037282898
-
Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression
-
Yeh, J., Hsu, W., Wang, J., Ho, S., and Kao, A. (2003) Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression. Respiration; International Review of Thoracic Diseases, 70, 32-35.
-
(2003)
Respiration; International Review of Thoracic Diseases
, vol.70
, pp. 32-35
-
-
Yeh, J.1
Hsu, W.2
Wang, J.3
Ho, S.4
Kao, A.5
-
101
-
-
1842477895
-
Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples
-
Penson, R., Oliva, E., Skates, S., Glyptis, T., Fuller, A.J., Goodman, A., and Selden, M. (2004) Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples. Gynecologic Oncology, 93, 98-106.
-
(2004)
Gynecologic Oncology
, vol.93
, pp. 98-106
-
-
Penson, R.1
Oliva, E.2
Skates, S.3
Glyptis, T.4
Fuller, A.J.5
Goodman, A.6
Selden, M.7
-
102
-
-
53049085702
-
ABCB (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/ carboplatin chemotherapy
-
Johnatty, S., Beesley, J., Paul, J., Fereday, S., Spurdle, A., Webb, P., Byth, K., Marsh, S., McLeod, H., Harnett, P., Brown, R., deFazio, A., and Chenevix-Trench, G. (2008) ABCB (MDR 1) polymorphisms and progression-free survival among women with ovarian cancer following paclitaxel/ carboplatin chemotherapy. Clinical Cancer Research, 14, 5594-5601.
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 5594-5601
-
-
Johnatty, S.1
Beesley, J.2
Paul, J.3
Fereday, S.4
Spurdle, A.5
Webb, P.6
Byth, K.7
Marsh, S.8
McLeod, H.9
Harnett, P.10
Brown, R.11
deFazio, A.12
Chenevix-trench, G.13
-
103
-
-
0141888537
-
The role of ABC transporters in clinical practice
-
Leonard, G., Fojo, T., and Bates, S. (2003) The role of ABC transporters in clinical practice. Oncologist, 8, 411-424.
-
(2003)
Oncologist
, vol.8
, pp. 411-424
-
-
Leonard, G.1
Fojo, T.2
Bates, S.3
-
104
-
-
0345688612
-
Mechanisms of taxol resistance related to microtubules
-
Orr, G., Verdier-Pinard, P., McDaid, H., and Horwitz, S. (2003) Mechanisms of taxol resistance related to microtubules. Oncogene, 22, 7280-7295.
-
(2003)
Oncogene
, vol.22
, pp. 7280-7295
-
-
Orr, G.1
Verdier-pinard, P.2
McDaid, H.3
Horwitz, S.4
-
105
-
-
12944277104
-
A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
-
Giannakakou, P., Gussio, R., Nogales, E., Downing, K., Zaharevitz, D., Bollbuck, B., Poy, G., Sackett, D., Nicolaou, K., and Fojo, T. (2000) A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 97, 2904-2909.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 2904-2909
-
-
Giannakakou, P.1
Gussio, R.2
Nogales, E.3
Downing, K.4
Zaharevitz, D.5
Bollbuck, B.6
Poy, G.7
Sackett, D.8
Nicolaou, K.9
Fojo, T.10
-
106
-
-
0033063875
-
Paclitaxel resistance in non-small-cell lung cancer associated with b-tubulin gene mutations
-
Monzo, M., Rosell, R., Sanchez, J., Lee, J., O'Brate, A., Gonzalez-Larriba, J., Alberola, V., Lorenzo, J., Nunez, L., Ro, J., and Martin, C. (1999) Paclitaxel resistance in non-small-cell lung cancer associated with b-tubulin gene mutations. Journal of Clinical Oncology, 17, 1786-1793.
-
(1999)
Journal of Clinical Oncology
, vol.17
, pp. 1786-1793
-
-
Monzo, M.1
Rosell, R.2
Sanchez, J.3
Lee, J.4
O'Brate, A.5
Gonzalez-larriba, J.6
Alberola, V.7
Lorenzo, J.8
Nunez, L.9
Ro, J.10
Martin, C.11
-
107
-
-
0029550441
-
Novel mechanism of resistance of paclitaxel in human K562 leukemia cells by combined selection with PSC833
-
Jaffrezou, J., Dumontet, C., Derry, W., Duran, G., Chen, G., Tsuchiya, E., Wilson, L., Jordan, M., and Sikic, S. (1995) Novel mechanism of resistance of paclitaxel in human K562 leukemia cells by combined selection with PSC833. Oncology Research, 7, 517-527.
-
(1995)
Oncology Research
, vol.7
, pp. 517-527
-
-
Jaffrezou, J.1
Dumontet, C.2
Derry, W.3
Duran, G.4
Chen, G.5
Tsuchiya, E.6
Wilson, L.7
Jordan, M.8
Sikic, S.9
-
108
-
-
0030931827
-
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific b-tubulin isotypes
-
Kavallaris, M., Kuo, D.Y., Burkhart, C.A., Regl, D.L., Norris, M.D., Haber, M., and Horwitz, S.B. (1997) Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific b-tubulin isotypes. The Journal of Clinical Investigation, 100, 1282-1293.
-
(1997)
The Journal of Clinical Investigation
, vol.100
, pp. 1282-1293
-
-
Kavallaris, M.1
Kuo, D.Y.2
Burkhart, C.A.3
Regl, D.L.4
Norris, M.D.5
Haber, M.6
Horwitz, S.B.7
-
109
-
-
0031985608
-
Altered b-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells
-
Ranganathan, S., Benetatos, C., Colarusso, P., Dexter, D., and Hudes, G. (1998) Altered b-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells. British Journal of Cancer, 77, 562-566.
-
(1998)
British Journal of Cancer
, vol.77
, pp. 562-566
-
-
Ranganathan, S.1
Benetatos, C.2
Colarusso, P.3
Dexter, D.4
Hudes, G.5
-
110
-
-
23044435044
-
Expression of class III b-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy
-
Seve, P., Isaaac, S., Tredan, O., Souquet, P.-J., Pacheco, Y., Perol, M., Lafanechere, L., Penet, A., Peiller, E.-L., and Dumontet, C. (2005) Expression of class III b-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy. Clinical Cancer Research, 11, 5481-5486.
-
(2005)
Clinical Cancer Research
, vol.11
, pp. 5481-5486
-
-
Seve, P.1
Isaaac, S.2
Tredan, O.3
Souquet, P.-J.4
Pacheco, Y.5
Perol, M.6
Lafanechere, L.7
Penet, A.8
Peiller, E.-L.9
Dumontet, C.10
-
111
-
-
19944430079
-
Class III b-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients
-
Mozzetti, S., Ferlini, C., Concolino, P., Filippetti, E., Raspaglio, G., Prislei, S., Gallo, D., Martinelli, E., Ranelletti, F.O., Ferrandina, G., and Scambia, G. (2005) Class III b-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients. Clinical Cancer Research, 11, 298-305.
-
(2005)
Clinical Cancer Research
, vol.11
, pp. 298-305
-
-
Mozzetti, S.1
Ferlini, C.2
Concolino, P.3
Filippetti, E.4
Raspaglio, G.5
Prislei, S.6
Gallo, D.7
Martinelli, E.8
Ranelletti, F.O.9
Ferrandina, G.10
Scambia, G.11
-
112
-
-
0034807154
-
Expression of b-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen correlation with sensitivity to microtubule active agents
-
Nicoletti, M., Valoti, G., Giannakakou, P., Zhan, Z., Kim, J., Lucchini, V., Landoni, F., Mayo, J., Giavazzi, R., and Fojo, T. (2001) Expression of b-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-anticancer drug screen correlation with sensitivity to microtubule active agents. Clinical Cancer Research, 7, 2912-2922.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 2912-2922
-
-
Nicoletti, M.1
Valoti, G.2
Giannakakou, P.3
Zhan, Z.4
Kim, J.5
Lucchini, V.6
Landoni, F.7
Mayo, J.8
Giavazzi, R.9
Fojo, T.10
-
113
-
-
0033867211
-
Modulation of drug resistance by a-tubulin in paclitaxel-resistant human cancer cell lines
-
Han, H.K.-H., Gehrke, L., Tahir, S., Credo, R., Cherian, S., Sham, H., Rosenberg, S., and Ng, S. (2000) Modulation of drug resistance by a-tubulin in paclitaxel-resistant human cancer cell lines. European Journal of Cancer (Oxford, England: 1990), 36, 1565-1571.
-
(2000)
European Journal of Cancer (Oxford, England: 1990)
, vol.36
, pp. 1565-1571
-
-
Han, H.K.-H.1
Gehrke, L.2
Tahir, S.3
Credo, R.4
Cherian, S.5
Sham, H.6
Rosenberg, S.7
Ng, S.8
-
114
-
-
0020371138
-
Structure-activity study of cytotoxicity and microtubule assembly by taxol and related taxanes
-
Parness, J., Kingston, D.G.I., Powell, R.G., Harracksingh, C., and Horwitz, S.B. (1982) Structure-activity study of cytotoxicity and microtubule assembly by taxol and related taxanes. Biochemical and Biophysical Research Communications, 105, 1082-1089.
-
(1982)
Biochemical and Biophysical Research Communications
, vol.105
, pp. 1082-1089
-
-
Parness, J.1
Kingston, D.G.I.2
Powell, R.G.3
Harracksingh, C.4
Horwitz, S.B.5
-
115
-
-
0021715055
-
Preparation and biological activity of taxol acetates
-
Mellado, W., Magri, N.F., Kingston, D.G.I., Garcia-Arenas, R., Orr, G.A., and Horwitz, S.B. (1984) Preparation and biological activity of taxol acetates. Biochemical and Biophysical Research Communications, 124, 329-336.
-
(1984)
Biochemical and Biophysical Research Communications
, vol.124
, pp. 329-336
-
-
Mellado, W.1
Magri, N.F.2
Kingston, D.G.I.3
Garcia-arenas, R.4
Orr, G.A.5
Horwitz, S.B.6
-
116
-
-
0000052734
-
Taxol and Taxotere: discovery, chemistry, and structure-activity relationships
-
Guenard, D., Gueritte-Voegelein, F., and Potier, P. (1993) Taxol and Taxotere: discovery, chemistry, and structure-activity relationships. Accounts of Chemical Research, 26, 160-167.
-
(1993)
Accounts of Chemical Research
, vol.26
, pp. 160-167
-
-
Guenard, D.1
Gueritte-voegelein, F.2
Potier, P.3
-
117
-
-
85127683706
-
The medicinal chemistry of taxol
-
(M. Suffness), CRC Press, New York
-
1: Science and Applications (ed. M. Suffness), CRC Press, New York, pp. 317-375.
-
(1995)
1: Science and Applications
, pp. 317-375
-
-
Georg, G.I.1
Boge, T.C.2
Cheruvallath, Z.S.3
Clowers, J.S.4
Harriman, G.C.B.5
Hepperle, M.6
Park, H.7
-
118
-
-
77957102852
-
Recent advances in the medicinal chemistry of taxoid anticancer agents
-
(B.E. Maryanoff and A.B. Reitz), JAI Press, Greenwich, CT
-
Ojima, I., Kuduk, S.D., and Chakravarty, S. (1998) Recent advances in the medicinal chemistry of taxoid anticancer agents, in Advances in Medicinal Chemistry (eds B.E. Maryanoff and A.B. Reitz), JAI Press, Greenwich, CT, pp. 69-124.
-
(1998)
Advances in Medicinal Chemistry
, pp. 69-124
-
-
Ojima, I.1
Kuduk, S.D.2
Chakravarty, S.3
-
119
-
-
0034041275
-
Recent advances in the chemistry of taxol
-
Kingston, D.G. (2000) Recent advances in the chemistry of taxol. Journal of Natural Products, 63, 726-734.
-
(2000)
Journal of Natural Products
, vol.63
, pp. 726-734
-
-
Kingston, D.G.1
-
120
-
-
0036048410
-
The chemistry of taxol and related taxoids
-
Kingston, D.G., Jagtap, P.G., Yuan, H., and Samala, L. (2002) The chemistry of taxol and related taxoids. Fortschritte der Chemie Organischer Naturstoffe, 84, 53-225.
-
(2002)
Fortschritte der Chemie Organischer Naturstoffe
, vol.84
, pp. 53-225
-
-
Kingston, D.G.1
Jagtap, P.G.2
Yuan, H.3
Samala, L.4
-
121
-
-
65249131138
-
Recent advances in the chemistry and biology of new generation taxoids
-
Ojima, I. and Das, M. (2009) Recent advances in the chemistry and biology of new generation taxoids. Journal of Natural Products, 72, 554-565.
-
(2009)
Journal of Natural Products
, vol.72
, pp. 554-565
-
-
Ojima, I.1
Das, M.2
-
122
-
-
0023905721
-
Modified taxols: 4. Synthesis and biological activity of taxols modified in the C13 side chain
-
Magri, N.F. and Kingston, D.G.I. (1988) Modified taxols: 4. Synthesis and biological activity of taxols modified in the C13 side chain. Journal of Natural Products, 51, 298-306.
-
(1988)
Journal of Natural Products
, vol.51
, pp. 298-306
-
-
Magri, N.F.1
Kingston, D.G.I.2
-
123
-
-
0025804190
-
Relationships between the structure of taxol analogues and their antimitotic activity
-
Gueritte-Voegelein, F., Guenard, D., Lavelle, F., LeGoff, M.-T., Mangatal, L., and Potier, P. (1991) Relationships between the structure of taxol analogues and their antimitotic activity. Journal of Medicinal Chemistry, 34, 992-998.
-
(1991)
Journal of Medicinal Chemistry
, vol.34
, pp. 992-998
-
-
Gueritte-voegelein, F.1
Guenard, D.2
Lavelle, F.3
LeGoff, M.-T.4
Mangatal, L.5
Potier, P.6
-
124
-
-
0027935479
-
Synthesis and structure-activity relationships of new antitumor taxoids: effects of cyclohexyl substitution at the C-3 and/or C-2 of Taxotere (Docetaxel)
-
Ojima, I., Duclos, O., Zucco, M., Bissery, M.-C., Combeau, C., Vrignaud, P., Riou, J.F., and Lavelle, F. (1994) Synthesis and structure-activity relationships of new antitumor taxoids: effects of cyclohexyl substitution at the C-3 and/or C-2 of Taxotere (Docetaxel). Journal of Medicinal Chemistry, 37, 2602-2608.
-
(1994)
Journal of Medicinal Chemistry
, vol.37
, pp. 2602-2608
-
-
Ojima, I.1
Duclos, O.2
Zucco, M.3
Bissery, M.-C.4
Combeau, C.5
Vrignaud, P.6
Riou, J.F.7
Lavelle, F.8
-
125
-
-
0029091896
-
0-(tert-butyl) 3-dephenyl analogs of paclitaxel and docetaxel
-
0-(tert-butyl) 3-dephenyl analogs of paclitaxel and docetaxel. Journal of Medicinal Chemistry, 38, 3821-3828.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 3821-3828
-
-
Ali, S.M.1
Hoemann, M.Z.2
Aube, J.3
Mitscher, L.A.4
Georg, G.I.5
McCall, R.6
Jayasinghe, L.R.7
-
126
-
-
0033581642
-
Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "Hydrophobic Collapse" conformation
-
Boge, T.C., Wu, Z.-J., Himes, R.H., Vander Velde, D.G., and Georg, G.I. (1999) Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "Hydrophobic Collapse" conformation. Bioorganic & Medicinal Chemistry Letters, 9, 3047-3052.
-
(1999)
Bioorganic & Medicinal Chemistry Letters
, vol.9
, pp. 3047-3052
-
-
Boge, T.C.1
Wu, Z.-J.2
Himes, R.H.3
Vander Velde, D.G.4
Georg, G.I.5
-
127
-
-
0034616754
-
Macrocycle formation by ring-closing metathesis (RCM): application to the syntheses of novel macrocyclic taxoids
-
Ojima, I., Lin, S., Inoue, T., Miller, M.L., Borella, C.P., Geng, X., and Walsh, J.J. (2000) Macrocycle formation by ring-closing metathesis (RCM): application to the syntheses of novel macrocyclic taxoids. Journal of the American Chemical Society, 122, 5343-5353.
-
(2000)
Journal of the American Chemical Society
, vol.122
, pp. 5343-5353
-
-
Ojima, I.1
Lin, S.2
Inoue, T.3
Miller, M.L.4
Borella, C.P.5
Geng, X.6
Walsh, J.J.7
-
128
-
-
0028825869
-
A new paclitaxel photoaffinity analog with a 3-(4-benzoylphenyl)propanoyl probe for characterization of drug-binding sites on tubulin and P-glycoprotein
-
Ojima, I., Duclos, O., Dormán, G., Simonot, B., Prestwich, G.D., Rao, S., Lerro, K.A., and Horwitz, S.B. (1995) A new paclitaxel photoaffinity analog with a 3-(4-benzoylphenyl)propanoyl probe for characterization of drug-binding sites on tubulin and P-glycoprotein. Journal of Medicinal Chemistry, 38, 3891-3894.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 3891-3894
-
-
Ojima, I.1
Duclos, O.2
Dormán, G.3
Simonot, B.4
Prestwich, G.D.5
Rao, S.6
Lerro, K.A.7
Horwitz, S.B.8
-
129
-
-
0032508365
-
0 -and 7-benzophenone analogs of taxol in the carboxyl terminal half or murine mdr1b P-glycoprotein
-
0 -and 7-benzophenone analogs of taxol in the carboxyl terminal half or murine mdr1b P-glycoprotein. Biochemistry, 37, 11272-11279.
-
(1998)
Biochemistry
, vol.37
, pp. 11272-11279
-
-
Wu, Q.1
Bounaud, P.-Y.2
Kuduk, S.3
Yang, C.-P.4
Ojima, I.5
Horwitz, S.6
Orr, G.7
-
130
-
-
0031008547
-
Synthesis and biological activity of A-nor-paclitaxel analogues
-
Chordia, M.C., Kingston, D.G.I., Hamel, E., Lin, C.M., Long, B.H., Fairchild, C.A., Johnston, K.A., and Rose, W.C. (1997) Synthesis and biological activity of A-nor-paclitaxel analogues. Bioorganic & Medicinal Chemistry, 5, 941-947.
-
(1997)
Bioorganic & Medicinal Chemistry
, vol.5
, pp. 941-947
-
-
Chordia, M.C.1
Kingston, D.G.I.2
Hamel, E.3
Lin, C.M.4
Long, B.H.5
Fairchild, C.A.6
Johnston, K.A.7
Rose, W.C.8
-
131
-
-
0028346210
-
1
-
1. The Journal of Organic Chemistry, 59, 515-517.
-
(1994)
The Journal of Organic Chemistry
, vol.59
, pp. 515-517
-
-
Ojima, I.1
Fenoglio, I.2
Park, Y.H.3
Sun, C.-M.4
Appendino, G.5
Pera, P.6
Bernacki, R.J.7
-
132
-
-
0028893726
-
Synthesis of biologically active 2-benzoyl paclitaxel analogues
-
Georg, G.I., Ali, S.M., Boge, T.C., Datta, A., Falborg, L., Park, H., Mejillano, M., and Hirnes, R.H. (1995) Synthesis of biologically active 2-benzoyl paclitaxel analogues. Bioorganic & Medicinal Chemistry Letters, 5, 259-264.
-
(1995)
Bioorganic & Medicinal Chemistry Letters
, vol.5
, pp. 259-264
-
-
Georg, G.I.1
Ali, S.M.2
Boge, T.C.3
Datta, A.4
Falborg, L.5
Park, H.6
Mejillano, M.7
Hirnes, R.H.8
-
133
-
-
0035191067
-
Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel
-
Chordia, M.D., Yuan, H., Jagtap, P.G., Kadow, J.F., Long, B.H., Fairchild, C.R., Johnstonc, K.A., and Kingston, D.G.I. (2001) Synthesis and bioactivity of 2,4-diacyl analogues of paclitaxel. Bioorganic & Medicinal Chemistry, 9, 171-178.
-
(2001)
Bioorganic & Medicinal Chemistry
, vol.9
, pp. 171-178
-
-
Chordia, M.D.1
Yuan, H.2
Jagtap, P.G.3
Kadow, J.F.4
Long, B.H.5
Fairchild, C.R.6
Johnstonc, K.A.7
Kingston, D.G.I.8
-
134
-
-
0028235069
-
Unexpectedly facile hydrolysis of the 2-benzoate group of taxol and syntheses of analogs with increased activities
-
Chaudhary, A.G., Gharpure, M.M., Rimoldi, J.M., Chordia, M.D., Gunatilaka, A.A.L., Kingston, D.G.I., Grover, S., Lin, C.M., and Hamel, E. (1994) Unexpectedly facile hydrolysis of the 2-benzoate group of taxol and syntheses of analogs with increased activities. Journal of the American Chemical Society, 116, 4097-4098.
-
(1994)
Journal of the American Chemical Society
, vol.116
, pp. 4097-4098
-
-
Chaudhary, A.G.1
Gharpure, M.M.2
Rimoldi, J.M.3
Chordia, M.D.4
Gunatilaka, A.A.L.5
Kingston, D.G.I.6
Grover, S.7
Lin, C.M.8
Hamel, E.9
-
135
-
-
0027730478
-
"Hydrophobic collapse" of taxol and Taxotere solution conformations in mixtures of water and organic solvent
-
Vander Velde, D.G., Georg, G.I., Grunewald, G.L., Gunn, C.W., and Mitscher, L.A. (1993) "Hydrophobic collapse" of taxol and Taxotere solution conformations in mixtures of water and organic solvent. Journal of the American Chemical Society, 1993, 11650-11651.
-
(1993)
Journal of the American Chemical Society
, vol.1993
, pp. 11650-11651
-
-
Vander Velde, D.G.1
Georg, G.I.2
Grunewald, G.L.3
Gunn, C.W.4
Mitscher, L.A.5
-
136
-
-
44949151663
-
Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel
-
Matesanz, R., Barasoain, I., Yang, C.-G., Wang, L., Li, X., Ines, C.D., Coderch, C., Gago, F., Barbero, J., Andreu, J., Fang, W.-S., and Diaz, J. (2008) Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel. Chemistry & Biology, 15, 573-585.
-
(2008)
Chemistry & Biology
, vol.15
, pp. 573-585
-
-
Matesanz, R.1
Barasoain, I.2
Yang, C.-G.3
Wang, L.4
Li, X.5
Ines, C.D.6
Coderch, C.7
Gago, F.8
Barbero, J.9
Andreu, J.10
Fang, W.-S.11
Diaz, J.12
-
137
-
-
10144251769
-
Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells
-
Ojima, I., Slater, J.C., Michaud, E., Kuduk, S.D., Bounaud, P.-Y., Vrignaud, P., Bissery, M.C., Veith, J.M., Pera, P., and Bernacki, R.J. (1996) Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells. Journal of Medicinal Chemistry, 39, 3889-3896.
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, pp. 3889-3896
-
-
Ojima, I.1
Slater, J.C.2
Michaud, E.3
Kuduk, S.D.4
Bounaud, P.-Y.5
Vrignaud, P.6
Bissery, M.C.7
Veith, J.M.8
Pera, P.9
Bernacki, R.J.10
-
138
-
-
0001400169
-
Studies on the chemistry of taxol
-
Kingston, D.G.I. (1998) Studies on the chemistry of taxol. Pure and Applied Chemistry, 70, 331-334.
-
(1998)
Pure and Applied Chemistry
, vol.70
, pp. 331-334
-
-
Kingston, D.G.I.1
-
139
-
-
0034714179
-
Synthesis and biological activity of C-6 and C-7 modified paclitaxels
-
Yuan, H., Fairchild, C.R., Liang, X., and Kingston, D.G.I. (2000) Synthesis and biological activity of C-6 and C-7 modified paclitaxels. Tetrahedron, 56, 6407-6414.
-
(2000)
Tetrahedron
, vol.56
, pp. 6407-6414
-
-
Yuan, H.1
Fairchild, C.R.2
Liang, X.3
Kingston, D.G.I.4
-
140
-
-
0035952988
-
Synthesis of metabolically blocked paclitaxel analogues
-
Wittman, M.D., Altstadt, T.J., Fairchild, C., Hansel, S., Johnston, K., Kadow, J.F., Long, B.H., Rose, W.C., Vyas, D.M., Wu, M.-J., and Zoeckler, M.E. (2001) Synthesis of metabolically blocked paclitaxel analogues. Bioorganic & Medicinal Chemistry Letters, 11, 809-810.
-
(2001)
Bioorganic & Medicinal Chemistry Letters
, vol.11
, pp. 809-810
-
-
Wittman, M.D.1
Altstadt, T.J.2
Fairchild, C.3
Hansel, S.4
Johnston, K.5
Kadow, J.F.6
Long, B.H.7
Rose, W.C.8
Vyas, D.M.9
Wu, M.-J.10
Zoeckler, M.E.11
-
141
-
-
0033529688
-
Synthesis and biological activity of a novel C4-C6 bridged paclitaxel analog
-
Yuan, H., Kingston, D.G.I., Sackett, D.L., and Hamel, E. (1999) Synthesis and biological activity of a novel C4-C6 bridged paclitaxel analog. Tetrahedron, 55, 9707-9716.
-
(1999)
Tetrahedron
, vol.55
, pp. 9707-9716
-
-
Yuan, H.1
Kingston, D.G.I.2
Sackett, D.L.3
Hamel, E.4
-
142
-
-
0028939437
-
Reaction of paclitaxel and 10-desacetyl baccatin III with diethylamino sulfurtrifluoride
-
Roth, G.P., Marshall, D.R., and Chen, S.-H. (1995) Reaction of paclitaxel and 10-desacetyl baccatin III with diethylamino sulfurtrifluoride. Tetrahedron Letters, 36, 1609-1612.
-
(1995)
Tetrahedron Letters
, vol.36
, pp. 1609-1612
-
-
Roth, G.P.1
Marshall, D.R.2
Chen, S.-H.3
-
143
-
-
0028806691
-
Highly water soluble taxol derivatives: 7-polyethylene glycol carbamates and carbonates
-
Greenwald, R.B., Pendri, A., and Bolikal, D. (1995) Highly water soluble taxol derivatives: 7-polyethylene glycol carbamates and carbonates. The Journal of Organic Chemistry, 60, 331-336.
-
(1995)
The Journal of Organic Chemistry
, vol.60
, pp. 331-336
-
-
Greenwald, R.B.1
Pendri, A.2
Bolikal, D.3
-
144
-
-
0035924214
-
Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476
-
Altstadt, T.J., Fairchild, C.R., Golik, J., Johnston, K.A., Kadow, J.F., Lee, F.Y., Long, B.H., Rose, W.C., Vyas, D.M., Wong, H., Wu, M.-J., and Wittman, M.D. (2001) Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476. Journal of Medicinal Chemistry, 44, 4577-4583.
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, pp. 4577-4583
-
-
Altstadt, T.J.1
Fairchild, C.R.2
Golik, J.3
Johnston, K.A.4
Kadow, J.F.5
Lee, F.Y.6
Long, B.H.7
Rose, W.C.8
Vyas, D.M.9
Wong, H.10
Wu, M.-J.11
Wittman, M.D.12
-
145
-
-
68049131597
-
Larotaxel: broadening the road with new taxanes
-
Metzger-Filho, O., Moulin, C., Azambuja, E.D., and Ahmad, A. (2009) Larotaxel: broadening the road with new taxanes. Expert Opinion on Investigational Drugs, 18, 1183-1189.
-
(2009)
Expert Opinion on Investigational Drugs
, vol.18
, pp. 1183-1189
-
-
Metzger-filho, O.1
Moulin, C.2
Azambuja, E.D.3
Ahmad, A.4
-
146
-
-
0027244913
-
Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol
-
Chen, S.-H., Fairchild, C., Mamber, S.W., and Farina, V. (1993) Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol. The Journal of Organic Chemistry, 58, 2927-2928.
-
(1993)
The Journal of Organic Chemistry
, vol.58
, pp. 2927-2928
-
-
Chen, S.-H.1
Fairchild, C.2
Mamber, S.W.3
Farina, V.4
-
147
-
-
0033583494
-
New photoaffinity analogs of paclitaxel
-
Ojima, I., Bounaud, P.-Y., and Ahern, D.G. (1999) New photoaffinity analogs of paclitaxel. Bioorganic & Medicinal Chemistry Letters, 9, 1189-1194.
-
(1999)
Bioorganic & Medicinal Chemistry Letters
, vol.9
, pp. 1189-1194
-
-
Ojima, I.1
Bounaud, P.-Y.2
Ahern, D.G.3
-
148
-
-
0033621479
-
Characterization of the taxol binding site on the microtubule: identification of Arg282 in b-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol
-
Rao, S., He, L., Chakravarty, S., Ojima, I., Orr, G., and Horwitz, S. (1999) Characterization of the taxol binding site on the microtubule: identification of Arg282 in b-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol. The Journal of Biological Chemistry, 274, 37990-37994.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 37990-37994
-
-
Rao, S.1
He, L.2
Chakravarty, S.3
Ojima, I.4
Orr, G.5
Horwitz, S.6
-
149
-
-
0030968741
-
Synthesis and evaluation of C-seco paclitaxel analogues
-
Appendino, G., Danieli, B., Jakupovic, J., Belloro, E., Seambia, G., and Bombardelli, E. (1997) Synthesis and evaluation of C-seco paclitaxel analogues. Tetrahedron Letters, 38, 4273-4276.
-
(1997)
Tetrahedron Letters
, vol.38
, pp. 4273-4276
-
-
Appendino, G.1
Danieli, B.2
Jakupovic, J.3
Belloro, E.4
Seambia, G.5
Bombardelli, E.6
-
150
-
-
16844378550
-
The seco-taxane IDN5390 is able to target class III b-tubulin and to overcome paclitaxel resistance
-
Ferlini, C., Raspaglio, G., Mozzetti, S., Cicchillitti, L., Filippetti, F., Gallo, D., Fattorusso, C., Campiani, G., and Scambia, G. (2005) The seco-taxane IDN5390 is able to target class III b-tubulin and to overcome paclitaxel resistance. Cancer Research, 65, 2397-2405.
-
(2005)
Cancer Research
, vol.65
, pp. 2397-2405
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
Cicchillitti, L.4
Filippetti, F.5
Gallo, D.6
Fattorusso, C.7
Campiani, G.8
Scambia, G.9
-
151
-
-
0029417352
-
Altered expression of M2, the class II-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance
-
Haber, M., Burkhart, C.A., Regl, D.L., Madafiglio, J., Norris, M.D., and Horwitz, S.B. (1995) Altered expression of M2, the class II-tubulin isotype, in a murine J774.2 cell line with a high level of taxol resistance. The Journal of Biological Chemistry, 270, 31269-31275.
-
(1995)
The Journal of Biological Chemistry
, vol.270
, pp. 31269-31275
-
-
Haber, M.1
Burkhart, C.A.2
Regl, D.L.3
Madafiglio, J.4
Norris, M.D.5
Horwitz, S.B.6
-
152
-
-
0032904694
-
Antisense oligonucleotides to class III b-tubulin sensitize drug-resistant cells to taxol
-
Kavallaris, M., Burkhart, C.A., and Horwitz, S.B. (1999) Antisense oligonucleotides to class III b-tubulin sensitize drug-resistant cells to taxol. British Journal of Cancer, 80, 1020-1025.
-
(1999)
British Journal of Cancer
, vol.80
, pp. 1020-1025
-
-
Kavallaris, M.1
Burkhart, C.A.2
Horwitz, S.B.3
-
153
-
-
65749106201
-
Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III b-tubulin
-
Pepe, A., Sun, L., Zanardi, I., Wu, X., Ferlini, C., Fontana, G., Bombardelli, E., and Ojima, I. (2009) Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III b-tubulin. Bioorganic & Medicinal Chemistry Letters, 19, 3300-3304.
-
(2009)
Bioorganic & Medicinal Chemistry Letters
, vol.19
, pp. 3300-3304
-
-
Pepe, A.1
Sun, L.2
Zanardi, I.3
Wu, X.4
Ferlini, C.5
Fontana, G.6
Bombardelli, E.7
Ojima, I.8
-
154
-
-
0034712232
-
The oxetane ring in taxol
-
Wang, M., Cornett, B., Nettles, J., Liotta, D.C., and Snyder, J.P. (2000) The oxetane ring in taxol. The Journal of Organic Chemistry, 65, 1059-1068.
-
(2000)
The Journal of Organic Chemistry
, vol.65
, pp. 1059-1068
-
-
Wang, M.1
Cornett, B.2
Nettles, J.3
Liotta, D.C.4
Snyder, J.P.5
-
155
-
-
0035906452
-
Novel D-seco paclitaxel analogues: synthesis, biological evaluation and model testing
-
Barboni, L., Datta, A., Dutta, D., Georg, G.I., Vander Velde, D.G., Himes, R.H., Wang, M., and Snyder, J.P. (2001) Novel D-seco paclitaxel analogues: synthesis, biological evaluation and model testing. The Journal of Organic Chemistry, 66, 3321-3329.
-
(2001)
The Journal of Organic Chemistry
, vol.66
, pp. 3321-3329
-
-
Barboni, L.1
Datta, A.2
Dutta, D.3
Georg, G.I.4
Vander Velde, D.G.5
Himes, R.H.6
Wang, M.7
Snyder, J.P.8
-
156
-
-
0025871603
-
Modified taxols: 5. Reaction of taxol with electrophilic reagents and preparation of a rearranged taxol derivative with tubulin assembly activity
-
Samaranayake, G., Magri, N.F., Jitrangsri, C., and Kingston, D.G.I. (1991) Modified taxols: 5. Reaction of taxol with electrophilic reagents and preparation of a rearranged taxol derivative with tubulin assembly activity. The Journal of Organic Chemistry, 56, 5114-5119.
-
(1991)
The Journal of Organic Chemistry
, vol.56
, pp. 5114-5119
-
-
Samaranayake, G.1
Magri, N.F.2
Jitrangsri, C.3
Kingston, D.G.I.4
-
157
-
-
0007953052
-
Synthesis and biological evaluation of D-ring-modified taxanes: 5(20)-azadocetaxel analogs
-
Marder-Karsenti, R., Dubois, J., Bricard, L., Guenard, D., and Gueritte-Voegelein, F. (1997) Synthesis and biological evaluation of D-ring-modified taxanes: 5(20)-azadocetaxel analogs. The Journal of Organic Chemistry, 62, 6631-6637.
-
(1997)
The Journal of Organic Chemistry
, vol.62
, pp. 6631-6637
-
-
Marder-karsenti, R.1
Dubois, J.2
Bricard, L.3
Guenard, D.4
Gueritte-voegelein, F.5
-
158
-
-
0033574481
-
Synthesis and biological evaluation of novel paclitaxel (taxol) D-ring modified analogues
-
Gunatilaka, A.A.L., Ramdayal, F.D., Sarragiotto, M.H., and Kingston, D.G.I. (1999) Synthesis and biological evaluation of novel paclitaxel (taxol) D-ring modified analogues. The Journal of Organic Chemistry, 64, 2694-2703.
-
(1999)
The Journal of Organic Chemistry
, vol.64
, pp. 2694-2703
-
-
Gunatilaka, A.A.L.1
Ramdayal, F.D.2
Sarragiotto, M.H.3
Kingston, D.G.I.4
-
159
-
-
0034728938
-
Synthesis of 5(20) deoxydocetaxel, a new active docetaxel analogue
-
Dubois, J., Thoret, S., Gueritte, F., and Guenard, D. (2000) Synthesis of 5(20) deoxydocetaxel, a new active docetaxel analogue. Tetrahedron Letters, 41, 3331-3334.
-
(2000)
Tetrahedron Letters
, vol.41
, pp. 3331-3334
-
-
Dubois, J.1
Thoret, S.2
Gueritte, F.3
Guenard, D.4
-
160
-
-
0024597827
-
Synthesis of congeners and prodrugs: 3. Water-soluble prodrugs of taxol with potent antitumor activity
-
Deutsch, H.M., Glinski, J.A., Hernandez, M., Haugwitz, R.D., Narayanan, V.L., Suffness, M., and Zalkow, L.H. (1989) Synthesis of congeners and prodrugs: 3. Water-soluble prodrugs of taxol with potent antitumor activity. Journal of Medicinal Chemistry, 32, 788-792.
-
(1989)
Journal of Medicinal Chemistry
, vol.32
, pp. 788-792
-
-
Deutsch, H.M.1
Glinski, J.A.2
Hernandez, M.3
Haugwitz, R.D.4
Narayanan, V.L.5
Suffness, M.6
Zalkow, L.H.7
-
161
-
-
33748226949
-
Chemistry and biology of taxol
-
Nicolaou, K.C., Dai, W.-M., and Guy, R.K. (1994) Chemistry and biology of taxol. Angewandte Chemie -International Edition in English, 33, 15-44.
-
(1994)
Angewandte Chemie -International Edition in English
, vol.33
, pp. 15-44
-
-
Nicolaou, K.C.1
Dai, W.-M.2
Guy, R.K.3
-
162
-
-
0032727981
-
Paclitaxel derivatives for targeted therapy of cancer: toward the development of smart taxanes
-
Safavy, A., Raisch, K.P., Khazaeli, M.B., Buchsbaum, D.J., and Bonner, J.A. (1999) Paclitaxel derivatives for targeted therapy of cancer: toward the development of smart taxanes. Journal of Medicinal Chemistry, 42, 4919-4924.
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, pp. 4919-4924
-
-
Safavy, A.1
Raisch, K.P.2
Khazaeli, M.B.3
Buchsbaum, D.J.4
Bonner, J.A.5
-
163
-
-
0031909425
-
New active paclitaxel glucuronide derivative with improved water solubility
-
Paradis, R. and Page, M. (1998) New active paclitaxel glucuronide derivative with improved water solubility. International Journal of Oncology, 12, 391-395.
-
(1998)
International Journal of Oncology
, vol.12
, pp. 391-395
-
-
Paradis, R.1
Page, M.2
-
164
-
-
0031857631
-
Antitumor activity of paclitaxel-2-glycinate conjugated to poly(ethylene glycol): a water-soluble prodrug
-
Pendri, A., Conover, C.D., and Greenwald, R.B. (1998) Antitumor activity of paclitaxel-2-glycinate conjugated to poly(ethylene glycol): a water-soluble prodrug. Anti-Cancer Drug Design, 13, 387-395.
-
(1998)
Anti-Cancer Drug Design
, vol.13
, pp. 387-395
-
-
Pendri, A.1
Conover, C.D.2
Greenwald, R.B.3
-
165
-
-
0035845748
-
Poly(ethylene glycol)-human serum albumin-paclitaxel conjugates: preparation, characterization and pharmacokinetics
-
Dosio, F., Arpicco, S., Brusa, P., Stella, B., and Cattel, L. (2001) Poly(ethylene glycol)-human serum albumin-paclitaxel conjugates: preparation, characterization and pharmacokinetics. Journal of Controlled Release, 76, 107-117.
-
(2001)
Journal of Controlled Release
, vol.76
, pp. 107-117
-
-
Dosio, F.1
Arpicco, S.2
Brusa, P.3
Stella, B.4
Cattel, L.5
-
166
-
-
0034998446
-
Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility
-
Niethammer, A., Gaedicke, G., Lode, H.N., and Wrasidlo, W. (2001) Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility. Bioconjugate Chemistry, 12, 414-420.
-
(2001)
Bioconjugate Chemistry
, vol.12
, pp. 414-420
-
-
Niethammer, A.1
Gaedicke, G.2
Lode, H.N.3
Wrasidlo, W.4
-
167
-
-
0032402572
-
1), mitomycin C and doxorubicin
-
1), mitomycin C and doxorubicin. Bioorganic & Medicinal Chemistry Letters, 8, 3347-3352.
-
(1998)
Bioorganic & Medicinal Chemistry Letters
, vol.8
, pp. 3347-3352
-
-
Dubowchik, G.M.1
Mosure, K.2
Knipe, J.O.3
Firestone, R.A.4
-
168
-
-
0027213794
-
1 and analogues determined by NMR spectroscopy and molecular modeling studies
-
1 and analogues determined by NMR spectroscopy and molecular modeling studies. Tetrahedron, 49, 6533-6544.
-
(1993)
Tetrahedron
, vol.49
, pp. 6533-6544
-
-
Dubois, J.1
Guenard, D.2
Gueritte-voegelein, F.3
Guedira, N.4
Potier, P.5
Gillet, B.6
Belocil, J.-C.7
-
169
-
-
0000813445
-
Structure of a synthetic taxol precursor: N-tert-butoxycarbonyl-10-deacetyl-N-debenzoyltaxol
-
Gueritte-Voegelein, F., Guenard, D., Mangatal, L., Potier, P., Guilhem, J., Cesario, M., and Pascard, C. (1990) Structure of a synthetic taxol precursor: N-tert-butoxycarbonyl-10-deacetyl-N-debenzoyltaxol. Acta Crystallographica, C46, 781-784.
-
(1990)
Acta Crystallographica
, vol.C46
, pp. 781-784
-
-
Gueritte-voegelein, F.1
Guenard, D.2
Mangatal, L.3
Potier, P.4
Guilhem, J.5
Cesario, M.6
Pascard, C.7
-
171
-
-
24944590338
-
The taxol pharmacophore and the T-taxol bridging principle
-
Kingston, D., Bane, S., and Snyder, J. (2005) The taxol pharmacophore and the T-taxol bridging principle. Cell Cycle (Georgetown, Tex.), 4, 279-289.
-
(2005)
Cell Cycle (Georgetown, Tex.)
, vol.4
, pp. 279-289
-
-
Kingston, D.1
Bane, S.2
Snyder, J.3
-
172
-
-
0030750497
-
A novel approach to the study of solution structures and dynamic behavior of paclitaxel and docetaxel using fluorine-containing analogs as probes
-
Ojima, I., Kuduk, S.D., Chakravarty, S., Ourevitch, M., and Bégué, J.-P. (1997) A novel approach to the study of solution structures and dynamic behavior of paclitaxel and docetaxel using fluorine-containing analogs as probes. Journal of the American Chemical Society, 119, 5519-5527.
-
(1997)
Journal of the American Chemical Society
, vol.119
, pp. 5519-5527
-
-
Ojima, I.1
Kuduk, S.D.2
Chakravarty, S.3
Ourevitch, M.4
Bégué, J.-P.5
-
173
-
-
0032495513
-
Structure of the ab tubulin dimer by electron crystallography
-
Nogales, E., Wolf, S.G., and Downing, K.H. (1998) Structure of the ab tubulin dimer by electron crystallography. Nature, 391, 199-203.
-
(1998)
Nature
, vol.391
, pp. 199-203
-
-
Nogales, E.1
Wolf, S.G.2
Downing, K.H.3
-
174
-
-
0028169689
-
0 -(p-Azidobenzamido)taxol photolabels the N-terminal 31 amino acids of b-tubulin
-
0 -(p-Azidobenzamido)taxol photolabels the N-terminal 31 amino acids of b-tubulin. The Journal of Biological Chemistry, 269, 3132-3134.
-
(1994)
The Journal of Biological Chemistry
, vol.269
, pp. 3132-3134
-
-
Rao, S.1
Krauss, N.E.2
Heerding, J.M.3
Swindell, C.S.4
Ringel, I.5
Orr, G.A.6
Horwitz, S.B.7
-
175
-
-
0028861177
-
Characterization of the taxol binding site on the microtubule: 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of b-tubulin
-
Rao, S., Orr, G.A., Chaudhary, A.G., Kingston, D.G.I., and Horwitz, S.B. (1995) Characterization of the taxol binding site on the microtubule: 2-(m-azidobenzoyl) taxol photolabels a peptide (amino acids 217-231) of b-tubulin. The Journal of Biological Chemistry, 270, 20235-20238.
-
(1995)
The Journal of Biological Chemistry
, vol.270
, pp. 20235-20238
-
-
Rao, S.1
Orr, G.A.2
Chaudhary, A.G.3
Kingston, D.G.I.4
Horwitz, S.B.5
-
176
-
-
0034681179
-
Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR
-
Li, Y., Poliks, B., Cegelski, L., Poliks, M., Gryczynski, Z., Piszczek, G., Jagtap, P., Studelska, D., Kingston, D., Schaefer, J., and Bane, S. (2000) Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR. Biochemistry, 39, 281-291.
-
(2000)
Biochemistry
, vol.39
, pp. 281-291
-
-
Li, Y.1
Poliks, B.2
Cegelski, L.3
Poliks, M.4
Gryczynski, Z.5
Piszczek, G.6
Jagtap, P.7
Studelska, D.8
Kingston, D.9
Schaefer, J.10
Bane, S.11
-
177
-
-
33846201709
-
REDOR NMR distance measurements for the tubulin-bound paclitaxel conformation
-
Paik, Y., Yang, C., Metaferia, B., Tang, S., Bane, S., Ravindra, R., Shanker, N., Alcaraz, A., Johnson, S., Schaefer, J., O'Connor, R., Cegelski, L., Snyder, J., and Kingston, D. (2007) REDOR NMR distance measurements for the tubulin-bound paclitaxel conformation. Journal of the American Chemical Society, 129, 361-370.
-
(2007)
Journal of the American Chemical Society
, vol.129
, pp. 361-370
-
-
Paik, Y.1
Yang, C.2
Metaferia, B.3
Tang, S.4
Bane, S.5
Ravindra, R.6
Shanker, N.7
Alcaraz, A.8
Johnson, S.9
Schaefer, J.10
O'Connor, R.11
Cegelski, L.12
Snyder, J.13
Kingston, D.14
-
178
-
-
0035942226
-
The binding conformation of taxol in b-tubulin: a model based on electron crystallographic density
-
Snyder, J., Nettles, J., Cornett, B., Downing, K., and Nogales, E. (2001) The binding conformation of taxol in b-tubulin: a model based on electron crystallographic density. Proceedings of the National Academy of Sciences of the United States of America, 98, 5312-5316.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, pp. 5312-5316
-
-
Snyder, J.1
Nettles, J.2
Cornett, B.3
Downing, K.4
Nogales, E.5
-
179
-
-
15744400734
-
Use of the tubulin-bound paclitaxel conformation for structure-based rational drug design
-
Geney, R., Sun, L., Pera, P., Bernack, R., Xia, S., Horwitz, S., Simmerling, C., and Ojima, I. (2005) Use of the tubulin-bound paclitaxel conformation for structure-based rational drug design. Chemistry & Biology, 12, 339-348.
-
(2005)
Chemistry & Biology
, vol.12
, pp. 339-348
-
-
Geney, R.1
Sun, L.2
Pera, P.3
Bernack, R.4
Xia, S.5
Horwitz, S.6
Simmerling, C.7
Ojima, I.8
-
180
-
-
33646116076
-
The T-taxol conformation
-
Alcaraz, A.A., Mehta, A.K., Johnson, S.A., and Snyder, J.P. (2006) The T-taxol conformation. Journal of Medicinal Chemistry, 49, 2478-2488.
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 2478-2488
-
-
Alcaraz, A.A.1
Mehta, A.K.2
Johnson, S.A.3
Snyder, J.P.4
-
181
-
-
67651115890
-
Recent advances in the study of the bioactive conformation of taxol
-
Sun, L., Simmerling, C., and Ojima, I. (2009) Recent advances in the study of the bioactive conformation of taxol. ChemMedChem, 4, 719-731.
-
(2009)
ChemMedChem
, vol.4
, pp. 719-731
-
-
Sun, L.1
Simmerling, C.2
Ojima, I.3
-
182
-
-
3042836538
-
The bioactive taxol conformation on b-tubulin: experimental evidence from highly active constrained analogs
-
Ganesh, T., Guza, R.C., Bane, S., Ravindra, R., Shanker, N., Lakdawala, A.S., Snyder, J.P., and Kingston, D.G.I. (2004) The bioactive taxol conformation on b-tubulin: experimental evidence from highly active constrained analogs. Proceedings of the National Academy of Sciences of the United States of America, 101, 10006-10011.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 10006-10011
-
-
Ganesh, T.1
Guza, R.C.2
Bane, S.3
Ravindra, R.4
Shanker, N.5
Lakdawala, A.S.6
Snyder, J.P.7
Kingston, D.G.I.8
-
183
-
-
33847398220
-
0 bridged paclitaxel analogues
-
0 bridged paclitaxel analogues. Journal of Medicinal Chemistry, 50, 713-725.
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, pp. 713-725
-
-
Ganesh, T.1
Yang, C.2
Norris, A.3
Glass, T.4
Bane, S.5
Ravindra, R.6
Banergee, A.7
Metaferia, B.8
Thomas, S.9
Giannakakou, P.10
Alcaraz, A.11
Lakdawala, A.12
Snyder, J.13
Kingston, D.14
-
184
-
-
58049221274
-
0BzN-linked macrocyclic taxoids
-
0BzN-linked macrocyclic taxoids. The Journal of Organic Chemistry, 73, 9584-9593.
-
(2008)
The Journal of Organic Chemistry
, vol.73
, pp. 9584-9593
-
-
Sun, L.1
Geng, X.2
Geney, R.3
Li, Y.4
Simmerling, C.5
Li, Z.6
Lauher, J.W.7
Xia, S.8
Horwitz, S.B.9
Veith, J.M.10
Pera, P.11
Bernacki, R.J.12
Ojima, I.13
-
185
-
-
45149145322
-
Rotational-echo double-resonance NMR
-
Gullion, T. and Schaefer, J. (1989) Rotational-echo double-resonance NMR. Journal of Magnetic Resonance (San Diego, Calif: 1997), 81, 196-200.
-
(1989)
Journal of Magnetic Resonance (San Diego, Calif: 1997)
, vol.81
, pp. 196-200
-
-
Gullion, T.1
Schaefer, J.2
-
186
-
-
0035834521
-
Refined structure of a,b-tubulin at 3.5 Ao resolution
-
Lowe, J., Li, H., Downing, K.H., and Nogales, E. (2001) Refined structure of a,b-tubulin at 3.5 Ao resolution. Journal of Molecular Biology, 313, 1045-1057.
-
(2001)
Journal of Molecular Biology
, vol.313
, pp. 1045-1057
-
-
Lowe, J.1
Li, H.2
Downing, K.H.3
Nogales, E.4
-
187
-
-
0037424365
-
Fast kinetics of taxol binding to microtubules: effects of solution variables and microtubule-associated proteins
-
Diaz, J., Barasoain, I., and Andreu, J. (2003) Fast kinetics of taxol binding to microtubules: effects of solution variables and microtubule-associated proteins. The Journal of Biological Chemistry, 278, 8407-8419.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 8407-8419
-
-
Diaz, J.1
Barasoain, I.2
Andreu, J.3
-
188
-
-
33846374429
-
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
-
Buey, R., Calvo, E., Barasoain, I., Pineda, O., Edler, M., Matesanz, R., Cerezo, G., Vanderwal, C., Day, B., Sorensen, E., Lopez, J., Andeu, J., Hamel, E., and Diaz, J. (2007) Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nature Chemical Biology, 3, 117-125.
-
(2007)
Nature Chemical Biology
, vol.3
, pp. 117-125
-
-
Buey, R.1
Calvo, E.2
Barasoain, I.3
Pineda, O.4
Edler, M.5
Matesanz, R.6
Cerezo, G.7
Vanderwal, C.8
Day, B.9
Sorensen, E.10
Lopez, J.11
Andeu, J.12
Hamel, E.13
Diaz, J.14
-
189
-
-
1542380040
-
Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization and cytotoxicity
-
Buey, R., Diaz, J., Andreu, J., O'Brate, A., Giannakakou, P., Nicolaou, K., Sasmal, P., Ritzen, A., and Namoto, K. (2004) Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization and cytotoxicity. Chemistry & Biology, 11, 225-236.
-
(2004)
Chemistry & Biology
, vol.11
, pp. 225-236
-
-
Buey, R.1
Diaz, J.2
Andreu, J.3
O'Brate, A.4
Giannakakou, P.5
Nicolaou, K.6
Sasmal, P.7
Ritzen, A.8
Namoto, K.9
-
190
-
-
0036321081
-
Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells
-
Lage, H. and Dietel, M.J. (2002) Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells. Journal of Cancer Research and Clinical Oncology, 128, 349-357.
-
(2002)
Journal of Cancer Research and Clinical Oncology
, vol.128
, pp. 349-357
-
-
Lage, H.1
Dietel, M.J.2
-
191
-
-
34547763870
-
MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma
-
O'Driscoll, L., Walsh, N., Larkin, A., Ballot, J., Ooi, W.S., Gullo, G., O'Connor, R., Clynes, M., Crown, J., and Kennedy, S. (2007) MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma. Anticancer Research, 27, 2115-2120.
-
(2007)
Anticancer Research
, vol.27
, pp. 2115-2120
-
-
O'Driscoll, L.1
Walsh, N.2
Larkin, A.3
Ballot, J.4
Ooi, W.S.5
Gullo, G.6
O'Connor, R.7
Clynes, M.8
Crown, J.9
Kennedy, S.10
-
192
-
-
0028034111
-
0 -dephenyldocetaxels
-
0 -dephenyldocetaxels. Bioorganic & Medicinal Chemistry Letters, 4, 2631-2634.
-
(1994)
Bioorganic & Medicinal Chemistry Letters
, vol.4
, pp. 2631-2634
-
-
Ojima, I.1
Duclos, O.2
Kuduk, S.D.3
Sun, C.-M.4
Slatert, J.C.5
Lavelle, F.6
Veith, J.M.7
Bernacki, R.J.8
-
193
-
-
0031049783
-
Synthesis and structure-activity relationships of non-aromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity
-
Ojima, I., Kuduk, S.D., Pera, P., Veith, J.M., and Bernacki, R.J. (1997) Synthesis and structure-activity relationships of non-aromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity. Journal of Medicinal Chemistry, 40, 279-285.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 279-285
-
-
Ojima, I.1
Kuduk, S.D.2
Pera, P.3
Veith, J.M.4
Bernacki, R.J.5
-
194
-
-
0033590281
-
Synthesis and structure-activity relationships of new second-generation taxoids
-
Ojima, I., Wang, T., Miller, M.L., Lin, S., Bollera, C.P., Geng, X., Pera, P., and Bernacki, R.J. (1999) Synthesis and structure-activity relationships of new second-generation taxoids. Bioorganic & Medicinal Chemistry Letters, 9, 3423-3428.
-
(1999)
Bioorganic & Medicinal Chemistry Letters
, vol.9
, pp. 3423-3428
-
-
Ojima, I.1
Wang, T.2
Miller, M.L.3
Lin, S.4
Bollera, C.P.5
Geng, X.6
Pera, P.7
Bernacki, R.J.8
-
195
-
-
44949142967
-
Design, synthesis, and biological evaluation of new-generation taxoids
-
Ojima, I., Chen, J., Sun, L., Borella, C.P., Wang, T., Miller, M.L., Lin, S., Geng, X., Kuznetsova, L., Qu, C., Gallager, D., Zhao, X., Zanardi, I., Xia, S., Horwitz, S.B., Mallen-St. Clair, J., Guerriero, J.L., Bar-Sagi, D., Veith, J.M., Pera, P., Bernacki, R.J. (2008) Design, synthesis, and biological evaluation of new-generation taxoids. Journal of Medicinal Chemistry, 51, 3203-3221.
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, pp. 3203-3221
-
-
Ojima, I.1
Chen, J.2
Sun, L.3
Borella, C.P.4
Wang, T.5
Miller, M.L.6
Lin, S.7
Geng, X.8
Kuznetsova, L.9
Qu, C.10
Gallager, D.11
Zhao, X.12
Zanardi, I.13
Xia, S.14
Horwitz, S.B.15
Clair, M.-S.J.16
Guerriero, J.L.17
Bar-sagi, D.18
Veith, J.M.19
Pera, P.20
Bernacki, R.J.21
more..
-
196
-
-
0011826255
-
Syntheses and structure-activity relationships of new taxoids
-
(G.I. Georg, T.T. Chen, I. Ojima, and D.M. Vyas), American Chemical Society, Washington, DC
-
Ojima, I., Park, Y.H., Fenoglio, I., Duclos, O., Sun, C.-M., Kuduk, S.D., Zucco, M., Appendino, G., Pera, P., Veith, J.M., Bernacki, R.J., Bissery, M.-C., Combeau, C., Vrignaud, P., Riou, J.F., and Lavelle, F. (1995) Syntheses and structure-activity relationships of new taxoids, in Taxane Anticancer Agents: Basic Science and Current Status, ACS Symposium Series 583 (eds G.I. Georg, T.T. Chen, I. Ojima, and D.M. Vyas), American Chemical Society, Washington, DC, pp. 262-275.
-
(1995)
Taxane Anticancer Agents: Basic Science and Current Status, ACS Symposium Series 583
, pp. 262-275
-
-
Ojima, I.1
Park, Y.H.2
Fenoglio, I.3
Duclos, O.4
Sun, C.-M.5
Kuduk, S.D.6
Zucco, M.7
Appendino, G.8
Pera, P.9
Veith, J.M.10
Bernacki, R.J.11
Bissery, M.-C.12
Combeau, C.13
Vrignaud, P.14
Riou, J.F.15
Lavelle, F.16
-
197
-
-
0034543235
-
Antitumor activity of novel taxanes that act as cytotoxic agents and P-glycoprotein inhibitors at the same time
-
Ferlini, C., Distefano, M., Pignatelli, F., Lin, S., Riva, A., Bombardelli, E., Mancuso, S., Ojima, I., and Scambia, G. (2000) Antitumor activity of novel taxanes that act as cytotoxic agents and P-glycoprotein inhibitors at the same time. British Journal of Cancer, 83, 1762-1768.
-
(2000)
British Journal of Cancer
, vol.83
, pp. 1762-1768
-
-
Ferlini, C.1
Distefano, M.2
Pignatelli, F.3
Lin, S.4
Riva, A.5
Bombardelli, E.6
Mancuso, S.7
Ojima, I.8
Scambia, G.9
-
198
-
-
84889483761
-
Unique properties of fluorine and their relevance to medicinal chemistry and chemical biology
-
(I. Ojima), Wiley-Blackwell, Chichester
-
Yamazaki, T., Taguchi, T., and Ojima, I. (2009) Unique properties of fluorine and their relevance to medicinal chemistry and chemical biology, in Fluorine in Medicinal Chemistry and Chemical Biology (ed. I. Ojima), Wiley-Blackwell, Chichester, pp. 3-46.
-
(2009)
Fluorine in Medicinal Chemistry and Chemical Biology
, pp. 3-46
-
-
Yamazaki, T.1
Taguchi, T.2
Ojima, I.3
-
199
-
-
50549084514
-
0-trifluoromethyl-taxoids
-
0-trifluoromethyl-taxoids. Journal of Fluorine Chemistry, 129, 817-828.
-
(2008)
Journal of Fluorine Chemistry
, vol.129
, pp. 817-828
-
-
Kuznetsova, L.1
Pepe, A.2
Ungureanu, I.M.3
Pera, P.4
Bernacki, R.J.5
Ojima, I.6
-
200
-
-
0033948409
-
0 -difluoromethyl-taxoids
-
0 -difluoromethyl-taxoids. Bioorganic & Medicinal Chemistry Letters, 8, 1619-1628.
-
(2000)
Bioorganic & Medicinal Chemistry Letters
, vol.8
, pp. 1619-1628
-
-
Ojima, I.1
Lin, S.2
Slater, J.C.3
Wang, T.4
Pera, P.5
Bernacki, R.J.6
Ferlini, C.7
Scambia, G.8
-
201
-
-
0031023523
-
0-trifluoromethyl taxoids
-
0-trifluoromethyl taxoids. Bioorganic & Medicinal Chemistry Letters, 7, 133-138.
-
(1997)
Bioorganic & Medicinal Chemistry Letters
, vol.7
, pp. 133-138
-
-
Ojima, I.1
Slater, J.C.2
Pera, P.3
Veith, J.M.4
Abouabdellah, A.5
Bégué, J.-P.6
Bernacki, R.J.7
-
202
-
-
33748711014
-
Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes
-
Gut, I., Ojima, I., Vaclavikova, R., Simek, P., Horsky, S., Soucek, P., Kondrova, E., Kuznetsova, L.V., and Chen, J. (2006) Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes. Xenobiotica; The Fate of Foreign Compounds in Biological Systems, 36, 772-792.
-
(2006)
Xenobiotica; The Fate of Foreign Compounds in Biological Systems
, vol.36
, pp. 772-792
-
-
Gut, I.1
Ojima, I.2
Vaclavikova, R.3
Simek, P.4
Horsky, S.5
Soucek, P.6
Kondrova, E.7
Kuznetsova, L.V.8
Chen, J.9
-
203
-
-
36749104372
-
Organofluorine chemistry at the biomedical interface: a case study on fluoro-taxoid anticancer agents
-
(V. Soloshonok, K. Mikami, T. Yamazaki, J.T. Welch, and J. Honek), American Chemical Society/Oxford University Press, Washington, DC
-
Ojima, I., Kuznetsova, L., and Sun, L. (2007) Organofluorine chemistry at the biomedical interface: a case study on fluoro-taxoid anticancer agents, in Current Fluoroorganic Chemistry: New Synthetic Directions, Technologies, Materials and Biological Applications, ACS Symposium Series 949 (eds V. Soloshonok, K. Mikami, T. Yamazaki, J.T. Welch, and J. Honek), American Chemical Society/Oxford University Press, Washington, DC, pp. 288-304.
-
(2007)
Current Fluoroorganic Chemistry: New Synthetic Directions, Technologies, Materials and Biological Applications, ACS Symposium Series 949
, pp. 288-304
-
-
Ojima, I.1
Kuznetsova, L.2
Sun, L.3
-
204
-
-
84867395928
-
0 -difluorovinyl taxoids
-
0 -difluorovinyl taxoids. Journal of Fluorine Chemistry, 143, 177-188.
-
(2012)
Journal of Fluorine Chemistry
, vol.143
, pp. 177-188
-
-
Kuznetsova, L.1
Sun, L.2
Chen, J.3
Zhao, X.4
Seitz, J.5
Das, M.6
Li, Y.7
Veith, J.M.8
Pera, P.9
Bernacki, R.J.10
Xia, S.11
Horwitz, S.B.12
Ojima, I.13
-
205
-
-
84866729228
-
Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ ADR-RES cells
-
Ehrlichová, E., Ojima, I., Václavíková, R., Němcová-Fürstová, V., Vobořilová, J., Šimek, P., Horský, S., Souček, P., Kovář, J., and Gut, I. (2012) Transport, metabolism, cytotoxicity and effects of novel taxanes on the cell cycle in MDA-MB-435 and NCI/ ADR-RES cells. Naunyn-Schmiedeberg's Archives of Pharmacology, 385, 1035-1048.
-
(2012)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.385
, pp. 1035-1048
-
-
Ehrlichová, E.1
Ojima, I.2
Václavíková, R.3
Němcová-fürstová, V.4
Vobořilová, J.5
Šimek, P.6
Horský, S.7
Souček, P.8
Kovář, J.9
Gut, I.10
-
206
-
-
37049073616
-
14b-Hydroxy-l0-deacetylbaccatin III, a new taxane from Himalayan yew (Taxus wallichiana Zucc.)
-
Appendino, G., Gariboldi, P., Gabetta, B., Pace, R., Bombardelli, E., and Viterbo, D. (1992) 14b-Hydroxy-l0-deacetylbaccatin III, a new taxane from Himalayan yew (Taxus wallichiana Zucc.). Journal of the Chemical Society, Perkin Transactions 1, 2925-2929.
-
(1992)
Journal of the Chemical Society, Perkin Transactions
, vol.1
, pp. 2925-2929
-
-
Appendino, G.1
Gariboldi, P.2
Gabetta, B.3
Pace, R.4
Bombardelli, E.5
Viterbo, D.6
-
207
-
-
15644364107
-
Syntheses and structure-activity relationships of taxoids derived from 14b-hydroxy-10-deacetylbaccatin III
-
Ojima, I., Slater, J.C., Kuduk, S.D., Takeuchi, C.S., Gimi, R.H., Sun, C.-M., Park, Y.H., Pera, P., Veith, J.M., and Bernacki, R.J. (1997) Syntheses and structure-activity relationships of taxoids derived from 14b-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry, 40, 267-278.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 267-278
-
-
Ojima, I.1
Slater, J.C.2
Kuduk, S.D.3
Takeuchi, C.S.4
Gimi, R.H.5
Sun, C.-M.6
Park, Y.H.7
Pera, P.8
Veith, J.M.9
Bernacki, R.J.10
-
208
-
-
0028343398
-
Synthesis and biological activity of 14b-hydroxydocetaxel
-
Ojima, I., Fenoglio, I., Park, Y.H., Pera, P., and Bernacki, R.J. (1994) Synthesis and biological activity of 14b-hydroxydocetaxel. Bioorganic & Medicinal Chemistry Letters, 4, 1571-1574.
-
(1994)
Bioorganic & Medicinal Chemistry Letters
, vol.4
, pp. 1571-1574
-
-
Ojima, I.1
Fenoglio, I.2
Park, Y.H.3
Pera, P.4
Bernacki, R.J.5
-
209
-
-
0028301263
-
Structure-activity relationships of new taxoids derived from 14b-hydroxy-10-deacetylbaccatin III
-
Ojima, I., Park, Y.H., Sun, C.-M., Fenoglio, I., Appendino, G., Pera, P., and Bernacki, R.J. (1994) Structure-activity relationships of new taxoids derived from 14b-hydroxy-10-deacetylbaccatin III. Journal of Medicinal Chemistry, 37, 1408-1410.
-
(1994)
Journal of Medicinal Chemistry
, vol.37
, pp. 1408-1410
-
-
Ojima, I.1
Park, Y.H.2
Sun, C.-M.3
Fenoglio, I.4
Appendino, G.5
Pera, P.6
Bernacki, R.J.7
-
210
-
-
0026489553
-
Isolation of 9-dihydro-13-acetylbaccatin III from Taxus canadensis
-
Gunawardana, G., Premachandran, U., Burres, N.S., Whitten, D., Henry, R., Spanton, S., and McAlpine, J.B. (1992) Isolation of 9-dihydro-13-acetylbaccatin III from Taxus canadensis. Journal of Natural Products, 55, 1686-1689.
-
(1992)
Journal of Natural Products
, vol.55
, pp. 1686-1689
-
-
Gunawardana, G.1
Premachandran, U.2
Burres, N.S.3
Whitten, D.4
Henry, R.5
Spanton, S.6
McAlpine, J.B.7
-
211
-
-
0026801061
-
Taxanes isolated from Taxus canadensis
-
Zamir, L.O., Nedea, M.E., Belair, S., Sauriol, F., Mamer, O., Jacqmain, E., Jean, F.I., and Carneau, F.X. (1992) Taxanes isolated from Taxus canadensis. Tetrahedron Letters, 33, 5173-5176.
-
(1992)
Tetrahedron Letters
, vol.33
, pp. 5173-5176
-
-
Zamir, L.O.1
Nedea, M.E.2
Belair, S.3
Sauriol, F.4
Mamer, O.5
Jacqmain, E.6
Jean, F.I.7
Carneau, F.X.8
-
212
-
-
0037041250
-
New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals
-
Ishiyama, T., Iimura, S., Ohsuki, S., Uoto, K., Terasawa, H., and Soga, T. (2002) New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals. Bioorganic & Medicinal Chemistry Letters, 12, 1083-1086.
-
(2002)
Bioorganic & Medicinal Chemistry Letters
, vol.12
, pp. 1083-1086
-
-
Ishiyama, T.1
Iimura, S.2
Ohsuki, S.3
Uoto, K.4
Terasawa, H.5
Soga, T.6
-
213
-
-
0041833673
-
New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 4
-
Takeda, Y., Uoto, K., Chiba, J., Horiuchi, T., Iwahana, M., Atsumi, R., Ono, C., Terasawab, H., and Soga, H. (2003) New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 4. Bioorganic & Medicinal Chemistry, 11, 4431-4447.
-
(2003)
Bioorganic & Medicinal Chemistry
, vol.11
, pp. 4431-4447
-
-
Takeda, Y.1
Uoto, K.2
Chiba, J.3
Horiuchi, T.4
Iwahana, M.5
Atsumi, R.6
Ono, C.7
Terasawab, H.8
Soga, H.9
-
214
-
-
18744382450
-
New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 3
-
Takeda, Y., Yoshinoa, T., Uoto, K., Chiba, J., Ishiyama, T., Iwahana, M., Jimbo, T., Tanaka, N., Terasawa, H., and Soga, T. (2003) New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 3. Bioorganic & Medicinal Chemistry Letters, 13, 185-190.
-
(2003)
Bioorganic & Medicinal Chemistry Letters
, vol.13
, pp. 185-190
-
-
Takeda, Y.1
Yoshinoa, T.2
Uoto, K.3
Chiba, J.4
Ishiyama, T.5
Iwahana, M.6
Jimbo, T.7
Tanaka, N.8
Terasawa, H.9
Soga, T.10
-
215
-
-
2442689451
-
New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 5
-
Takeda, Y., Uoto, K., Iwahana, M., Jimbo, T., Nagata, M., Atsumi, R., Ono, C., Tanaka, N., Terasawa, H., and Soga, T. (2004) New highly active taxoids from 9b-dihydrobaccatin-9,10-acetals: Part 5. Bioorganic & Medicinal Chemistry Letters, 21, 3209-3215.
-
(2004)
Bioorganic & Medicinal Chemistry Letters
, vol.21
, pp. 3209-3215
-
-
Takeda, Y.1
Uoto, K.2
Iwahana, M.3
Jimbo, T.4
Nagata, M.5
Atsumi, R.6
Ono, C.7
Tanaka, N.8
Terasawa, H.9
Soga, T.10
-
216
-
-
0038419962
-
DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo
-
Shionoya, M., Jimbo, T., Kitagawa, M., Soga, T., and Tohgo, A. (2003) DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Science, 94, 459-466.
-
(2003)
Cancer Science
, vol.94
, pp. 459-466
-
-
Shionoya, M.1
Jimbo, T.2
Kitagawa, M.3
Soga, T.4
Tohgo, A.5
-
217
-
-
0028175036
-
Paclitaxel (taxol) and docetaxel (Taxotere): not simply two of a kind
-
Verweij, J., Clavel, M., and Chevalier, B. (1994) Paclitaxel (taxol) and docetaxel (Taxotere): not simply two of a kind. Annals of Oncology, 5, 495-505.
-
(1994)
Annals of Oncology
, vol.5
, pp. 495-505
-
-
Verweij, J.1
Clavel, M.2
Chevalier, B.3
-
218
-
-
0031758794
-
A phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer
-
Valero, V., Jones, S.E., vonHoff, D.D., Booser, D.J., Mennel, R.G., Ravdin, P.M., Holmes, F.A., Rahman, Z., Schottstaedt, M.W., Erban, J.K., Esparza-Guerra, L., Earhart, R.H., Hortobagyi, G.N., and Burris, H.A., III (1998) A phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer. Journal of Clinical Oncology, 16, 3362-3368.
-
(1998)
Journal of Clinical Oncology
, vol.16
, pp. 3362-3368
-
-
Valero, V.1
Jones, S.E.2
vonHoff, D.D.3
Booser, D.J.4
Mennel, R.G.5
Ravdin, P.M.6
Holmes, F.A.7
Rahman, Z.8
Schottstaedt, M.W.9
Erban, J.K.10
Esparza-guerra, L.11
Earhart, R.H.12
Hortobagyi, G.N.13
Burris, H.A.14
-
219
-
-
18244423415
-
Docetaxel for patients with paclitaxel-resistant Mullerian carcinoma
-
Verschraegen, C., Sittisomwong, T., Kudelka, A., Guedes, E., Steger, M., Nelson-Taylor, T., Vincent, M., Rogers, R., Atkinson, E., and Kavanagh, J. (2000) Docetaxel for patients with paclitaxel-resistant Mullerian carcinoma. Journal of Clinical Oncology, 18, 2733-2739.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 2733-2739
-
-
Verschraegen, C.1
Sittisomwong, T.2
Kudelka, A.3
Guedes, E.4
Steger, M.5
Nelson-taylor, T.6
Vincent, M.7
Rogers, R.8
Atkinson, E.9
Kavanagh, J.10
-
220
-
-
0029110526
-
Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: preclinical experience
-
Bissery, M., Nohynek, G., Sanderink, G., and Lavelle, F. (1995) Docetaxel (Taxotere): a review of preclinical and clinical experience. Part I: preclinical experience. Anti-Cancer Drugs, 6, 339-355.
-
(1995)
Anti-Cancer Drugs
, vol.6
, pp. 339-355
-
-
Bissery, M.1
Nohynek, G.2
Sanderink, G.3
Lavelle, F.4
-
221
-
-
0028291647
-
Phase I study of docetaxel administered as a 1-hour intravenous infusion on a weekly basis
-
Tomiak, E., Piccart, M., Kerger, J., Lips, S., Awada, A., Valeriola, D.D., Ravoet, C., Lossignol, D., Sculier, J., and Auzannet, V. (1994) Phase I study of docetaxel administered as a 1-hour intravenous infusion on a weekly basis. Journal of Clinical Oncology, 12, 1458-1467.
-
(1994)
Journal of Clinical Oncology
, vol.12
, pp. 1458-1467
-
-
Tomiak, E.1
Piccart, M.2
Kerger, J.3
Lips, S.4
Awada, A.5
Valeriola, D.D.6
Ravoet, C.7
Lossignol, D.8
Sculier, J.9
Auzannet, V.10
-
222
-
-
0028989720
-
Docetaxel (Taxotere), a review of preclinical and clinical experience. Part II: clinical experience
-
Oosterom, A.V., Schrijvers, D., and Schrijvers, D. (1995) Docetaxel (Taxotere), a review of preclinical and clinical experience. Part II: clinical experience. Anti-Cancer Drugs, 6, 356-368.
-
(1995)
Anti-Cancer Drugs
, vol.6
, pp. 356-368
-
-
Oosterom, A.V.1
Schrijvers, D.2
Schrijvers, D.3
-
223
-
-
0028824166
-
Phase II trial of docetaxel in advanced anthracycline-resistant or anthracenedione-resistant breast cancer
-
Ravdin, R., Burris, H.A. III, Cook, G., Eisenberg, P., Kane, M., Bierman, W., Mortimer, J., Genevois, E., and Bellet, R. (1995) Phase II trial of docetaxel in advanced anthracycline-resistant or anthracenedione-resistant breast cancer. Journal of Clinical Oncology, 13, 2879-2885.
-
(1995)
Journal of Clinical Oncology
, vol.13
, pp. 2879-2885
-
-
Ravdin, R.1
Burris, H.A.2
Cook, G.3
Eisenberg, P.4
Kane, M.5
Bierman, W.6
Mortimer, J.7
Genevois, E.8
Bellet, R.9
-
224
-
-
0028827482
-
Phase II trial of docetaxel: a new, highly effective antineoplastic agent in the management of patients with anthracycline-resistant metastatic breast cancer
-
Valero, V., Holmes, F., Walters, R., Theriault, R., Esparza, L., Fraschini, G., Fonseca, G., Bellet, R., Buzdar, A., and Hortobagyi, G. (1995) Phase II trial of docetaxel: a new, highly effective antineoplastic agent in the management of patients with anthracycline-resistant metastatic breast cancer. Journal of Clinical Oncology, 13, 2886-2894.
-
(1995)
Journal of Clinical Oncology
, vol.13
, pp. 2886-2894
-
-
Valero, V.1
Holmes, F.2
Walters, R.3
Theriault, R.4
Esparza, L.5
Fraschini, G.6
Fonseca, G.7
Bellet, R.8
Buzdar, A.9
Hortobagyi, G.10
-
225
-
-
0028837396
-
Docetaxel is a major cytotoxic drug for the treatment of advanced breast cancer: a phase II trial of the clinical screening cooperative group of the European organization for research and treatment of cancer
-
Chevallier, B., Fumoleau, P., Kerbrat, P., Dieras, V., Roche, H., Krakowski, I., Azli, N., Bayssas, M., Lentz, M., and Glabbeke, M.V. (1995) Docetaxel is a major cytotoxic drug for the treatment of advanced breast cancer: a phase II trial of the clinical screening cooperative group of the European organization for research and treatment of cancer. Journal of Clinical Oncology, 13, 314-322.
-
(1995)
Journal of Clinical Oncology
, vol.13
, pp. 314-322
-
-
Chevallier, B.1
Fumoleau, P.2
Kerbrat, P.3
Dieras, V.4
Roche, H.5
Krakowski, I.6
Azli, N.7
Bayssas, M.8
Lentz, M.9
Glabbeke, M.V.10
-
226
-
-
21144435932
-
Adjuvant docetaxel for node-positive breast cancer
-
Martin, M., Pienkowski, T., Mackey, J., Pawlicki, M., Guastalla, J., Weaver, C., Tomiak, E., Al-Tweigeri, T., Chap, L., Juhos, E., Guevin, R., Howell, A., Fornadnder, T., Hainsworth, J., Coleman, R., Winholes, J., Modiano, M., Pinter, T., Tang, S., Colwell, B., Prady, C., Provencher, L., Walde, D., Rodriguez-Lescure, A., Hugh, J., Loret, C., Rupin, M., Blitz, S., Jacovs, P., Murawsky, M., Riva, A., and Vogel, C. (2005) Adjuvant docetaxel for node-positive breast cancer. New England Journal of Medicine, 352, 2302-2312.
-
(2005)
New England Journal of Medicine
, vol.352
, pp. 2302-2312
-
-
Martin, M.1
Pienkowski, T.2
Mackey, J.3
Pawlicki, M.4
Guastalla, J.5
Weaver, C.6
Tomiak, E.7
Al-tweigeri, T.8
Chap, L.9
Juhos, E.10
Guevin, R.11
Howell, A.12
Fornadnder, T.13
Hainsworth, J.14
Coleman, R.15
Winholes, J.16
Modiano, M.17
Pinter, T.18
Tang, S.19
Colwell, B.20
Prady, C.21
Provencher, L.22
Walde, D.23
Rodriguez-lescure, A.24
Hugh, J.25
Loret, C.26
Rupin, M.27
Blitz, S.28
Jacovs, P.29
Murawsky, M.30
Riva, A.31
Vogel, C.32
more..
-
227
-
-
33750949065
-
Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 study group
-
Cutsem, E.V., Moiseyenko, V., Tjulandin, S., Majlis, A., Constenla, M., Boni, B., Rodrigues, A., Fodor, M., Chao, Y., Voznyi, E., Risse, M.-L., and Ajani, J. (2006) Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 study group. Journal of Clinical Oncology, 24, 4991-4997.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. 4991-4997
-
-
Cutsem, E.V.1
Moiseyenko, V.2
Tjulandin, S.3
Majlis, A.4
Constenla, M.5
Boni, B.6
Rodrigues, A.7
Fodor, M.8
Chao, Y.9
Voznyi, E.10
Risse, M.-L.11
Ajani, J.12
-
228
-
-
0034095853
-
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens
-
Fossella, R., DeVore, R., Kerr, R., Crawford, J., Natale, R., Dunphy, F., Kalman, L., Miller, V., Lee, J., Moore, M., Gandara, D., Karp, D., Vokes, E., Kris, M., Kim, Y., Gamza, F., and Hammershaimb, L. (2000) Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. Journal of Clinical Oncology, 18, 2354-2362.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 2354-2362
-
-
Fossella, R.1
DeVore, R.2
Kerr, R.3
Crawford, J.4
Natale, R.5
Dunphy, F.6
Kalman, L.7
Miller, V.8
Lee, J.9
Moore, M.10
Gandara, D.11
Karp, D.12
Vokes, E.13
Kris, M.14
Kim, Y.15
Gamza, F.16
Hammershaimb, L.17
-
229
-
-
0042413836
-
Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group
-
Fossella, F., Pereira, J., Pawel, J.V., Pluzanska, A., Gorbounova, V., Kaukel, E., Mattson, K., Ramlau, R., Szczesna, A., Fidias, P., Millward, M., and Belani, C. (2003) Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. Journal of Clinical Oncology, 21, 3016-3024.
-
(2003)
Journal of Clinical Oncology
, vol.21
, pp. 3016-3024
-
-
Fossella, F.1
Pereira, J.2
Pawel, J.V.3
Pluzanska, A.4
Gorbounova, V.5
Kaukel, E.6
Mattson, K.7
Ramlau, R.8
Szczesna, A.9
Fidias, P.10
Millward, M.11
Belani, C.12
-
230
-
-
11144229621
-
Approval summary: docetaxel in combination with prednisone for the treatment of androgen-independent hormone-refractory prostate cancer
-
Dagher, R., Li, N., Abraham, S., Rahman, A., Sridhara, R., and Pazdur, R. (2004) Approval summary: docetaxel in combination with prednisone for the treatment of androgen-independent hormone-refractory prostate cancer. Clinical Cancer Research, 10, 8147-8151.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 8147-8151
-
-
Dagher, R.1
Li, N.2
Abraham, S.3
Rahman, A.4
Sridhara, R.5
Pazdur, R.6
-
231
-
-
35548966042
-
Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer
-
Vermorken, J., Remenar, E., Herpen, C.V., Gorila, T., Mesia, R., Degardin, M., Stewart, J., Jelic, S., Betka, J., Preiss, J., Weyndaert, D.V.D., Awada, A., Cupissol, D., Kienzer, H., Rey, A., Desaunois, I., Bernier, J., and Lefebvre, J.-L. (2007) Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. The New England Journal of Medicine, 357, 1695-1704.
-
(2007)
The New England Journal of Medicine
, vol.357
, pp. 1695-1704
-
-
Vermorken, J.1
Remenar, E.2
Herpen, C.V.3
Gorila, T.4
Mesia, R.5
Degardin, M.6
Stewart, J.7
Jelic, S.8
Betka, J.9
Preiss, J.10
Weyndaert, D.V.D.11
Awada, A.12
Cupissol, D.13
Kienzer, H.14
Rey, A.15
Desaunois, I.16
Bernier, J.17
Lefebvre, J.-L.18
-
232
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock, I., Wit, R.D., Berry, W., Horti, J., Pluzanska, A., Chi, K., Oudard, S., Theodore, C., James, N., Turesson, I., Rosenthal, M., and Eisenberger, M. (2004) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. The New England Journal of Medicine, 351, 1502-1512.
-
(2004)
The New England Journal of Medicine
, vol.351
, pp. 1502-1512
-
-
Tannock, I.1
Wit, R.D.2
Berry, W.3
Horti, J.4
Pluzanska, A.5
Chi, K.6
Oudard, S.7
Theodore, C.8
James, N.9
Turesson, I.10
Rosenthal, M.11
Eisenberger, M.12
-
233
-
-
62549091454
-
Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial
-
Hugh, J., Hanson, H., Cheang, M., Nielsen, T., Perou, C., Dumontet, C., Reed, J., Krajewska, M., Treilleux, I., Rupin, M., Manherini, E., Mackey, J., Martin, M., and Vogel, C. (2009) Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial. Journal of Clinical Oncology, 27, 1168-1176.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 1168-1176
-
-
Hugh, J.1
Hanson, H.2
Cheang, M.3
Nielsen, T.4
Perou, C.5
Dumontet, C.6
Reed, J.7
Krajewska, M.8
Treilleux, I.9
Rupin, M.10
Manherini, E.11
Mackey, J.12
Martin, M.13
Vogel, C.14
-
234
-
-
16244414000
-
Docetaxel for treatment of solid tumours: a systematic review of clinical data
-
Montero, A., Fossella, F., Hortobagyi, G., and Valero, V. (2005) Docetaxel for treatment of solid tumours: a systematic review of clinical data. The Lancet Oncology, 6, 229-239.
-
(2005)
The Lancet Oncology
, vol.6
, pp. 229-239
-
-
Montero, A.1
Fossella, F.2
Hortobagyi, G.3
Valero, V.4
-
235
-
-
37849035252
-
Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials
-
Laurentiis, M.D., Cancello, G., Dágostino, D., Giuliano, M., Giordano, A., Monagna, E., Lauria, R., Forestieri, V., Esposito, A., Silvestro, L., Pennacchio, R., Cricitiello, C., Montanino, A., Limite, G., Bianco, A., and Placido, S.D. (2008) Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials. Journal of Clinical Oncology, 26, 44-53.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 44-53
-
-
Laurentiis, M.D.1
Cancello, G.2
Dágostino, D.3
Giuliano, M.4
Giordano, A.5
Monagna, E.6
Lauria, R.7
Forestieri, V.8
Esposito, A.9
Silvestro, L.10
Pennacchio, R.11
Cricitiello, C.12
Montanino, A.13
Limite, G.14
Bianco, A.15
Placido, S.D.16
-
236
-
-
0036534121
-
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
-
Esteva, F., Valero, V., Booser, D., Guerra, L., Murray, J., Pusztai, L., Cristofanilli, M., Arun, B., Esmaeli, B., Fitsche, H., Sneige, N., Smith, T., and Hortobagyi, G. (2002) Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer. Journal of Clinical Oncology, 20, 1800-1808.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 1800-1808
-
-
Esteva, F.1
Valero, V.2
Booser, D.3
Guerra, L.4
Murray, J.5
Pusztai, L.6
Cristofanilli, M.7
Arun, B.8
Esmaeli, B.9
Fitsche, H.10
Sneige, N.11
Smith, T.12
Hortobagyi, G.13
-
237
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
-
Marty, M., Cognetti, F., Maraninchi, D., Snyder, R., Mauriac, L., Tubiana-Hulin, M., Chan, S., Grimes, D., Anton, A., Lluch, A., Kennedy, J., O'Byrne, K., Conte, P., Green, M., Ward, C., Mayne, K., and Extra, J.-M. (2005) Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. Journal of Clinical Oncology, 23, 4265-4274.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
Snyder, R.4
Mauriac, L.5
Tubiana-hulin, M.6
Chan, S.7
Grimes, D.8
Anton, A.9
Lluch, A.10
Kennedy, J.11
O'Byrne, K.12
Conte, P.13
Green, M.14
Ward, C.15
Mayne, K.16
Extra, J.-M.17
-
238
-
-
79951982754
-
Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens
-
Valero, V., Forbes, J., Pegram, M., Pienkowski, T., Eiermann, W., Minckwitz, G.V., Roche, H., Martin, M., Crown, J., Mackey, J., Fumoleau, P., Rolski, J., Mrsic-Krmpotic, Z., Jagiello-Gruszfeld, A., Riva, A., Buyse, M., Taupin, H., Sauter, G., Press, M., and Slamon, D. (2011) Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens. Journal of Clinical Oncology, 29, 149-156.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 149-156
-
-
Valero, V.1
Forbes, J.2
Pegram, M.3
Pienkowski, T.4
Eiermann, W.5
Minckwitz, G.V.6
Roche, H.7
Martin, M.8
Crown, J.9
Mackey, J.10
Fumoleau, P.11
Rolski, J.12
Mrsic-krmpotic, Z.13
Jagiello-gruszfeld, A.14
Riva, A.15
Buyse, M.16
Taupin, H.17
Sauter, G.18
Press, M.19
Slamon, D.20
more..
-
239
-
-
84858701839
-
Efficacy results of node-negative HER2-amplified breast cancer subset from BCIRG 006 study: a phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin, and trastuzumab (TCH)
-
Valero, V., Slamon, D., Wiermann, W., Robert, N., Pienkowski, T., Martin, M., Mackey, J., Lindsay, M., Bee-Munteanu, V., Press, M., Sauter, G., and Crown, J. (2011) Efficacy results of node-negative HER2-amplified breast cancer subset from BCIRG 006 study: a phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin, and trastuzumab (TCH). Journal of Clinical Oncology, 29, s553.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. s553
-
-
Valero, V.1
Slamon, D.2
Wiermann, W.3
Robert, N.4
Pienkowski, T.5
Martin, M.6
Mackey, J.7
Lindsay, M.8
Bee-munteanu, V.9
Press, M.10
Sauter, G.11
Crown, J.12
-
240
-
-
73349115249
-
Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer trial
-
Joensuu, H., Bono, P., Kataja, V., Alanko, T., Kokko, R., Asola, R., Utriainen, T., Turpeenniemi-Hujanen, T., Jyrkkio, S., Moykkynen, K., Helle, L., Ingalsuo, S., Pajunen, M., Huusko, M., Salminen, T., Auvinen, P., Leinonen, H., Leinonen, M., Isola, J., and Kellokumpu-Lehtinen, P.-L. (2009) Fluorouracil, epirubicin, and cyclophosphamide with either docetaxel or vinorelbine, with or without trastuzumab, as adjuvant treatments of breast cancer: final results of the FinHer trial. Journal of Clinical Oncology, 27, 5685-5692.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 5685-5692
-
-
Joensuu, H.1
Bono, P.2
Kataja, V.3
Alanko, T.4
Kokko, R.5
Asola, R.6
Utriainen, T.7
Turpeenniemi-hujanen, T.8
Jyrkkio, S.9
Moykkynen, K.10
Helle, L.11
Ingalsuo, S.12
Pajunen, M.13
Huusko, M.14
Salminen, T.15
Auvinen, P.16
Leinonen, H.17
Leinonen, M.18
Isola, J.19
Kellokumpu-lehtinen, P.-L.20
more..
-
241
-
-
84876291029
-
Epirubicin plus cyclophosphamide followed by docetaxel plus trastuzumab and bevacizumab as neoadjuvant therapy for HER2-positive locally advanced breast cancer (LABC) or as adjuvant therapy for HER2-positive pathologic stage III breast cancer (PS3BC): a phase II trial of the SNABP Foundation Research Group
-
Smith, J., Buyse, M., Rastogi, P., Geyer, Jr. C., Jacobs, S., Patocskai, E., and Wolmark, N. (2009) Epirubicin plus cyclophosphamide followed by docetaxel plus trastuzumab and bevacizumab as neoadjuvant therapy for HER2-positive locally advanced breast cancer (LABC) or as adjuvant therapy for HER2-positive pathologic stage III breast cancer (PS3BC): a phase II trial of the SNABP Foundation Research Group. Journal of Clinical Oncology, 27, s580.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. s580
-
-
Smith, J.1
Buyse, M.2
Rastogi, P.3
Geyer, C.4
Jacobs, S.5
Patocskai, E.6
Wolmark, N.7
-
242
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Miles, D., Chan, A., Dirix, L., Cortes, J., Pivot, X., Tomczak, P., Delozier, T., Sohn, J., Provencher, L., Puglisi, F., Harbeck, N., Steger, G., Schneeweiss, A., Wardley, A., Chlistalla, A., and Romieu, G. (2010) Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. Journal of Clinical Oncology, 28, 3239-3247.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 3239-3247
-
-
Miles, D.1
Chan, A.2
Dirix, L.3
Cortes, J.4
Pivot, X.5
Tomczak, P.6
Delozier, T.7
Sohn, J.8
Provencher, L.9
Puglisi, F.10
Harbeck, N.11
Steger, G.12
Schneeweiss, A.13
Wardley, A.14
Chlistalla, A.15
Romieu, G.16
-
243
-
-
1342268525
-
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003
-
Pfister, D., Johnson, D., Azzoli, C., Sause, W., Smith, T., Baker, Jr. B., Olak, J., Stover, D., Strawn, J., Turrisi, A., and Somerfield, M. (2004) American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. Journal of Clinical Oncology, 22, 330-353.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. 330-353
-
-
Pfister, D.1
Johnson, D.2
Azzoli, C.3
Sause, W.4
Smith, T.5
Baker, B.6
Olak, J.7
Stover, D.8
Strawn, J.9
Turrisi, A.10
Somerfield, M.11
-
244
-
-
0037399104
-
Docetaxel in non-small cell lung cancer: a review
-
Davies, A.M., Lara, Jr. P.N., Mack, P.C., and Gandara, D.R. (2003) Docetaxel in non-small cell lung cancer: a review. Expert Opinion on Pharmacotherapy, 4, 553-565.
-
(2003)
Expert Opinion on Pharmacotherapy
, vol.4
, pp. 553-565
-
-
Davies, A.M.1
Lara, P.N.2
Mack, P.C.3
Gandara, D.R.4
-
245
-
-
84926507328
-
S-1 combined with bi-weekly docetaxel for non-small cell lung cancer previously treated with platinum-based chemotherapy: a phase II study of North Japan Lung Cancer Group (NJLCG0701)
-
Ishimoto, O., Sakakibara, T., Maemondo, M., Inoue, A., Matsubara, N., Morikawa, N., Okudera, K., Usui, K., Suzuki, T., Nukiwa, T., and Sugawara, S. (2012) S-1 combined with bi-weekly docetaxel for non-small cell lung cancer previously treated with platinum-based chemotherapy: a phase II study of North Japan Lung Cancer Group (NJLCG0701). Cancer and Clinical Oncology, 1, 108-117.
-
(2012)
Cancer and Clinical Oncology
, vol.1
, pp. 108-117
-
-
Ishimoto, O.1
Sakakibara, T.2
Maemondo, M.3
Inoue, A.4
Matsubara, N.5
Morikawa, N.6
Okudera, K.7
Usui, K.8
Suzuki, T.9
Nukiwa, T.10
Sugawara, S.11
-
246
-
-
77954035012
-
Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial
-
Herbst, R., Sun, Y., Eberhardt, W., Germonpre, P., Saijo, N., Zhou, V., Wang, J., Li, L., Kabbinavar, F., Ichinose, Y., Qin, S., Zhang, L., Biesma, B., Heymach, J., Langmuir, P., Kennedy, S., Tada, H., and Johnson, B. (2010) Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. The Lancet Oncology, 11, 619-626.
-
(2010)
The Lancet Oncology
, vol.11
, pp. 619-626
-
-
Herbst, R.1
Sun, Y.2
Eberhardt, W.3
Germonpre, P.4
Saijo, N.5
Zhou, V.6
Wang, J.7
Li, L.8
Kabbinavar, F.9
Ichinose, Y.10
Qin, S.11
Zhang, L.12
Biesma, B.13
Heymach, J.14
Langmuir, P.15
Kennedy, S.16
Tada, H.17
Johnson, B.18
-
247
-
-
38349167518
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study
-
Berthold, D., Pond, G., Soban, F., Wit, R.D., Eisenberger, M., and Tannock, I. (2008) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study. Journal of Clinical Oncology, 26, 242-245.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 242-245
-
-
Berthold, D.1
Pond, G.2
Soban, F.3
Wit, R.D.4
Eisenberger, M.5
Tannock, I.6
-
248
-
-
75249096926
-
A phase II study of neoadjuvant chemotherapy with docetaxel and bevacizumab in patients (pts) with high-risk localized prostate cancer: a Prostate Cancer Clinical Trials Consortium Trial
-
Oh, W., Febbo, P., Richie, J., Fennessy, F., Scibelli, G., Hayes, J., Choueiri, T., Tempany, C., Taplin, M., and Ross, R. (2009) A phase II study of neoadjuvant chemotherapy with docetaxel and bevacizumab in patients (pts) with high-risk localized prostate cancer: a Prostate Cancer Clinical Trials Consortium Trial. Journal of Clinical Oncology, 27, s5060.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. s5060
-
-
Oh, W.1
Febbo, P.2
Richie, J.3
Fennessy, F.4
Scibelli, G.5
Hayes, J.6
Choueiri, T.7
Tempany, C.8
Taplin, M.9
Ross, R.10
-
249
-
-
77951518711
-
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate
-
Reid, A.H., Attard, G., Danila, D.C., Oommen, N.B., Olmos, D., Fong, P.C., Molife, L.R., Hunt, J., Messiou, C., Parker, C., Dearnaley, D., Swennenhuis, J.F., Terstappen, L.W., Lee, G., Kheoh, T., Molina, A., Ryan, C.J., Small, E., Scher, H.I., and deBono, J.S. (2010) Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate. Journal of Clinical Oncology, 28, 1489-1495.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 1489-1495
-
-
Reid, A.H.1
Attard, G.2
Danila, D.C.3
Oommen, N.B.4
Olmos, D.5
Fong, P.C.6
Molife, L.R.7
Hunt, J.8
Messiou, C.9
Parker, C.10
Dearnaley, D.11
Swennenhuis, J.F.12
Terstappen, L.W.13
Lee, G.14
Kheoh, T.15
Molina, A.16
Ryan, C.J.17
Small, E.18
Scher, H.I.19
deBono, J.S.20
more..
-
250
-
-
77956542827
-
Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel: final results of a multinational phase III trial (TROPIC)
-
de Bono, J.S., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J., Shen, L., Matthews, P., and Sartor, A. (2010) Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with docetaxel: final results of a multinational phase III trial (TROPIC). Journal of Clinical Oncology, 28, s4508.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. s4508
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.5
Shen, L.6
Matthews, P.7
Sartor, A.8
-
251
-
-
56849091919
-
Review of docetaxel in the treatment of gastric cancer
-
Tetzlaff, E., Cheng, J., and Ajani, J. (2008) Review of docetaxel in the treatment of gastric cancer. Therapeutics and Clinical Risk Management, 4, 999-1007.
-
(2008)
Therapeutics and Clinical Risk Management
, vol.4
, pp. 999-1007
-
-
Tetzlaff, E.1
Cheng, J.2
Ajani, J.3
-
252
-
-
77954574658
-
Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203
-
Sun, W., Powell, M., O'Dwyer, P.J., Catalano, P., Ansari, R.H., and Benson, A.B. III (2010) Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. Journal of Clinical Oncology, 28, 2947-2951.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 2947-2951
-
-
Sun, W.1
Powell, M.2
O'Dwyer, P.J.3
Catalano, P.4
Ansari, R.H.5
Benson, A.B.6
-
253
-
-
61649104588
-
Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer
-
Enzinger, P., Ryan, D., Clark, J., Muzikansky, A., Earle, C., Kulke, M., Meyerhardt, J., Blaszkowsky, L., Zhu, A., Fidias, P., Vincitore, M., Mayer, R., and Fuchs, C. (2009) Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer. Annals of Oncology, 20, 475-480.
-
(2009)
Annals of Oncology
, vol.20
, pp. 475-480
-
-
Enzinger, P.1
Ryan, D.2
Clark, J.3
Muzikansky, A.4
Earle, C.5
Kulke, M.6
Meyerhardt, J.7
Blaszkowsky, L.8
Zhu, A.9
Fidias, P.10
Vincitore, M.11
Mayer, R.12
Fuchs, C.13
-
254
-
-
77951204618
-
Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: results of a phase II clinical trial
-
Kelsen, D., Jhawer, M., Ilson, D., Tse, A., Randazzo, J., Robinson, E., Capanu, M., and Shah, M. (2009) Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: results of a phase II clinical trial. Journal of Clinical Oncology, 27, s4512.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. s4512
-
-
Kelsen, D.1
Jhawer, M.2
Ilson, D.3
Tse, A.4
Randazzo, J.5
Robinson, E.6
Capanu, M.7
Shah, M.8
-
255
-
-
79952355358
-
Phase II study of modified docetaxel, cisplatin, and fluororuacil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma
-
Shah, M., Jhawer, M., Ilson, D., Lefkowitz, R., Robinson, E., Capanu, M., and Kelsen, D. (2011) Phase II study of modified docetaxel, cisplatin, and fluororuacil with bevacizumab in patients with metastatic gastroesophageal adenocarcinoma. Journal of Clinical Oncology, 29, 868-874.
-
(2011)
Journal of Clinical Oncology
, vol.29
, pp. 868-874
-
-
Shah, M.1
Jhawer, M.2
Ilson, D.3
Lefkowitz, R.4
Robinson, E.5
Capanu, M.6
Kelsen, D.7
-
256
-
-
56849089479
-
Phase II trial of docetaxel, cisplatin, irinotecan, and bevacizumab in metastatic esophagogastric cancer
-
Enzinger, P., Ryan, D., Regan, E., Lehman, N., Abrams, T., Hezel, A., Fidias, P., Sequist, L., Blaszkowsky, L., and Fuchs, C. (2008) Phase II trial of docetaxel, cisplatin, irinotecan, and bevacizumab in metastatic esophagogastric cancer. Journal of Clinical Oncology, 26, s4552.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. s4552
-
-
Enzinger, P.1
Ryan, D.2
Regan, E.3
Lehman, N.4
Abrams, T.5
Hezel, A.6
Fidias, P.7
Sequist, L.8
Blaszkowsky, L.9
Fuchs, C.10
-
257
-
-
77957160694
-
A phase II study of bevacizumab, oxaliplatin, and docetaxel in locally advanced and metastatic gastric and gastroesophageal junction cancers
-
El-Rayes, B., Zalupski, M., Bekai-Saab, T., Heilbrun, L., Hammad, N., Patel, B., Urba, S., Shields, A., Vaishampayan, U., Dawson, S., Almhanna, K., Smith, D., and Philip, P. (2010) A phase II study of bevacizumab, oxaliplatin, and docetaxel in locally advanced and metastatic gastric and gastroesophageal junction cancers. Annals of Oncology, 21, 1999-2004.
-
(2010)
Annals of Oncology
, vol.21
, pp. 1999-2004
-
-
El-rayes, B.1
Zalupski, M.2
Bekai-saab, T.3
Heilbrun, L.4
Hammad, N.5
Patel, B.6
Urba, S.7
Shields, A.8
Vaishampayan, U.9
Dawson, S.10
Almhanna, K.11
Smith, D.12
Philip, P.13
-
258
-
-
35548972994
-
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer
-
Posner, M.R., Hershock, D.M., Blajman, C.R., Mickiewicz, E., Winguist, E., Gorbounova, V., Tjulandin, S., Shin, D.M., Cullen, K., Ervin, T.J., Murphy, B.A., Raez, L.E., Cohen, R.B., Spaulding, M., Tishler, R.B., Roth, B., Viroglio, R.C., Venkatesan, V., Romanov, I., Agarwala, S., Harter, K.W., Dugan, M., Cmelak, A., Markoe, A.M., Read, P.W., Steinbrenner, L., Colevas, A.D., Norris, Jr. C.M., and Haddad, R.I. (2007) Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. The New England Journal of Medicine, 357, 1705-1715.
-
(2007)
The New England Journal of Medicine
, vol.357
, pp. 1705-1715
-
-
Posner, M.R.1
Hershock, D.M.2
Blajman, C.R.3
Mickiewicz, E.4
Winguist, E.5
Gorbounova, V.6
Tjulandin, S.7
Shin, D.M.8
Cullen, K.9
Ervin, T.J.10
Murphy, B.A.11
Raez, L.E.12
Cohen, R.B.13
Spaulding, M.14
Tishler, R.B.15
Roth, B.16
Viroglio, R.C.17
Venkatesan, V.18
Romanov, I.19
Agarwala, S.20
Harter, K.W.21
Dugan, M.22
Cmelak, A.23
Markoe, A.M.24
Read, P.W.25
Steinbrenner, L.26
Colevas, A.D.27
Norris, C.M.28
Haddad, R.I.29
more..
-
259
-
-
79151485327
-
Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial
-
Lorch, J., Goloubeva, O., Haddad, R., Cullen, K., Sarlis, N., Tishler, R., Tan, M., Fasciano, J., Sammartino, D., and Posner, M. (2011) Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial. The Lancet Oncology, 12, 153-159.
-
(2011)
The Lancet Oncology
, vol.12
, pp. 153-159
-
-
Lorch, J.1
Goloubeva, O.2
Haddad, R.3
Cullen, K.4
Sarlis, N.5
Tishler, R.6
Tan, M.7
Fasciano, J.8
Sammartino, D.9
Posner, M.10
-
260
-
-
9744223515
-
Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma
-
Vasey, P., Jayson, G., Gordon, A., Gabra, H., Coleman, R., Atkinson, R., Parkin, D., Paul, J., Hay, A., and Kaye, S. (2004) Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma. Journal of the National Cancer Institute, 96, 1682-1691.
-
(2004)
Journal of the National Cancer Institute
, vol.96
, pp. 1682-1691
-
-
Vasey, P.1
Jayson, G.2
Gordon, A.3
Gabra, H.4
Coleman, R.5
Atkinson, R.6
Parkin, D.7
Paul, J.8
Hay, A.9
Kaye, S.10
-
261
-
-
81155155669
-
Health-related quality of life outcomes of docetaxel/carboplatin combination therapy vs. sequential therapy with docetaxel then carboplatin in patients with relapsed, platinum-sensitive ovarian cancer: results from a randomized clinical trial
-
Pokrzywinski, R., Secord, A., Havrilesky, L., Puls, L., Holloway, R., Lewandowski, G., Higgins, R., Nycum, L., Kohler, M., and Revicki, D. (2011) Health-related quality of life outcomes of docetaxel/carboplatin combination therapy vs. sequential therapy with docetaxel then carboplatin in patients with relapsed, platinum-sensitive ovarian cancer: results from a randomized clinical trial. Gynecologic Oncology, 123, 505-510.
-
(2011)
Gynecologic Oncology
, vol.123
, pp. 505-510
-
-
Pokrzywinski, R.1
Secord, A.2
Havrilesky, L.3
Puls, L.4
Holloway, R.5
Lewandowski, G.6
Higgins, R.7
Nycum, L.8
Kohler, M.9
Revicki, D.10
-
262
-
-
84862550763
-
A multicenter, randomized, phase 2 clinical trial to evaluate the efficacy and safety of combination docetaxel and carboplatin and sequential therapy with docetaxel then carboplatin in patients with recurrent platinum-sensitive ovarian cancer
-
Secord, A., Berchuck, A., Higgins, R., Nycum, L., Kohler, M., Puls, L., Holloway, R., Lewandowski, G., Valea, F., and Havrilesky, L. (2012) A multicenter, randomized, phase 2 clinical trial to evaluate the efficacy and safety of combination docetaxel and carboplatin and sequential therapy with docetaxel then carboplatin in patients with recurrent platinum-sensitive ovarian cancer. Cancer, 118, 3283-3293.
-
(2012)
Cancer
, vol.118
, pp. 3283-3293
-
-
Secord, A.1
Berchuck, A.2
Higgins, R.3
Nycum, L.4
Kohler, M.5
Puls, L.6
Holloway, R.7
Lewandowski, G.8
Valea, F.9
Havrilesky, L.10
-
263
-
-
84862773728
-
Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer
-
Fu, S., Hennessy, B.T., Ng, C.S., Ju, Z., Coombes, K.R., Wolf, J.K., Sood, A.K., Levenback, C.F., Coleman, R.L., Kavanagh, J.J., Gershenson, D.M., Markman, M., Dice, K., Howard, A., Li, J., Li, Y., Stemke-Hale, K., Dyer, M., Atkinson, E., Jackson, E., Kundra, V., Kurzrock, R., Bast, Jr. R.C., and Mills, G.B. (2012) Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer. Gynecologic Oncology, 126, 47-53.
-
(2012)
Gynecologic Oncology
, vol.126
, pp. 47-53
-
-
Fu, S.1
Hennessy, B.T.2
Ng, C.S.3
Ju, Z.4
Coombes, K.R.5
Wolf, J.K.6
Sood, A.K.7
Levenback, C.F.8
Coleman, R.L.9
Kavanagh, J.J.10
Gershenson, D.M.11
Markman, M.12
Dice, K.13
Howard, A.14
Li, J.15
Li, Y.16
Stemke-hale, K.17
Dyer, M.18
Atkinson, E.19
Jackson, E.20
Kundra, V.21
Kurzrock, R.22
Bast, R.C.23
Mills, G.B.24
more..
-
264
-
-
1142291736
-
New anticancer agents and therapeutic strategies in development for solid cancers: a clinical perspective
-
Awada, A., Mano, M., Hendlisz, A., and Piccart, M. (2004) New anticancer agents and therapeutic strategies in development for solid cancers: a clinical perspective. Expert Review of Anticancer Therapy, 4, 53-60.
-
(2004)
Expert Review of Anticancer Therapy
, vol.4
, pp. 53-60
-
-
Awada, A.1
Mano, M.2
Hendlisz, A.3
Piccart, M.4
-
265
-
-
59449102526
-
Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
Mita, A., Denis, L., Rowinsky, E., Bono, J.D., Goetz, A., Ochoa, L., Forouzesh, B., Beeram, M., Patnaik, A., Molpus, K., Semiond, D., Besenval, M., and Tolcher, A. (2009) Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clinical Cancer Research, 15, 723-730.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 723-730
-
-
Mita, A.1
Denis, L.2
Rowinsky, E.3
Bono, J.D.4
Goetz, A.5
Ochoa, L.6
Forouzesh, B.7
Beeram, M.8
Patnaik, A.9
Molpus, K.10
Semiond, D.11
Besenval, M.12
Tolcher, A.13
-
266
-
-
84860397235
-
Clinical development of cabazitaxel for the treatment of castration-resistant prostate cancer
-
Tao, C.-K., Seng, S., Oh, W., and Galsky, M. (2011) Clinical development of cabazitaxel for the treatment of castration-resistant prostate cancer. Clinical Medicine Insights: Oncology, 5, 163-169.
-
(2011)
Clinical Medicine Insights: Oncology
, vol.5
, pp. 163-169
-
-
Tao, C.-K.1
Seng, S.2
Oh, W.3
Galsky, M.4
-
267
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomized open-label trial
-
Bono, J.D., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J.-P., Kocak, I., Gravis, G., Bodrogi, I., Mackenzie, M., Roessner, L.S.M., Gupta, S., and Sartor, A. (2010) Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomized open-label trial. Lancet, 376, 1147-1154.
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
Bono, J.D.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.-P.5
Kocak, I.6
Gravis, G.7
Bodrogi, I.8
Mackenzie, M.9
Roessner, L.S.M.10
Gupta, S.11
Sartor, A.12
-
268
-
-
77956319059
-
Cabazitaxel
-
Galsky, M., Dritselis, A., Kirkpatrick, P., and Oh, W. (2010) Cabazitaxel. Nature Reviews. Drug Discovery, 9, 677-678.
-
(2010)
Nature Reviews. Drug Discovery
, vol.9
, pp. 677-678
-
-
Galsky, M.1
Dritselis, A.2
Kirkpatrick, P.3
Oh, W.4
-
269
-
-
50849088935
-
A multicenter phase II study of XRP6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients
-
Pivot, X., Koralewski, P., Hidalgo, J., Chan, A., Goncalves, A., Schwartsmann, G., Assadourian, S., and Lotz, J. (2008) A multicenter phase II study of XRP6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients. Annals of Oncology, 19, 1547-1552.
-
(2008)
Annals of Oncology
, vol.19
, pp. 1547-1552
-
-
Pivot, X.1
Koralewski, P.2
Hidalgo, J.3
Chan, A.4
Goncalves, A.5
Schwartsmann, G.6
Assadourian, S.7
Lotz, J.8
-
270
-
-
77957332544
-
A dose-escalating study of XRP6258 in combination with capecitabine, in patients (pts) with metastatic breast cancer (MBC) progressing after anthracycline and taxane therapy
-
Besse-Hammer, T., Villanueva, C., Campone, M., Machiels, J., Awada, A., Magherini, E., Dubin, F., Semiond, D., and Pivot, X. (2009) A dose-escalating study of XRP6258 in combination with capecitabine, in patients (pts) with metastatic breast cancer (MBC) progressing after anthracycline and taxane therapy. Journal of Clinical Oncology, 27, s1053.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. s1053
-
-
Besse-hammer, T.1
Villanueva, C.2
Campone, M.3
Machiels, J.4
Awada, A.5
Magherini, E.6
Dubin, F.7
Semiond, D.8
Pivot, X.9
-
271
-
-
79953713649
-
A multicentre dose-escalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: a phase I/II study
-
Villanueva, C., Awada, A., Campone, M., Machiels, J., Besse, T., Magherini, E., Dubin, F., Semiond, D., and Pivot, X. (2011) A multicentre dose-escalating study of cabazitaxel (XRP6258) in combination with capecitabine in patients with metastatic breast cancer progressing after anthracycline and taxane treatment: a phase I/II study. European Journal of Cancer (Oxford, England: 1990), 47, 1037-1045.
-
(2011)
European Journal of Cancer (Oxford, England: 1990)
, vol.47
, pp. 1037-1045
-
-
Villanueva, C.1
Awada, A.2
Campone, M.3
Machiels, J.4
Besse, T.5
Magherini, E.6
Dubin, F.7
Semiond, D.8
Pivot, X.9
-
272
-
-
0035990845
-
Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-hour or a 3-hour infusion in patients with advanced solid tumors
-
Sessa, C., Cuvier, C., Caldiera, S., Bauer, J., Bosch, S.V.D., Monnerat, C., Semiond, D., Perard, D., Lebecq, A., Besenval, M., and Marty, M. (2002) Phase I clinical and pharmacokinetic studies of the taxoid derivative RPR 109881A administered as a 1-hour or a 3-hour infusion in patients with advanced solid tumors. Annals of Oncology, 13, 1140-1150.
-
(2002)
Annals of Oncology
, vol.13
, pp. 1140-1150
-
-
Sessa, C.1
Cuvier, C.2
Caldiera, S.3
Bauer, J.4
Bosch, S.V.D.5
Monnerat, C.6
Semiond, D.7
Perard, D.8
Lebecq, A.9
Besenval, M.10
Marty, M.11
-
273
-
-
0033863452
-
Phase I and pharmacokinetic study of a new taxoid, RPR 109881A, given as a 1-hour intravenous infusion in patients with advanced solid tumors
-
Kurata, T., Shimada, Y., Tamura, T., Yamamoto, N., Hyodo, I., Saeki, T., Takashima, S., Fujiwara, K., Wakasugi, H., and Kashimura, M. (2000) Phase I and pharmacokinetic study of a new taxoid, RPR 109881A, given as a 1-hour intravenous infusion in patients with advanced solid tumors. Journal of Clinical Oncology, 18, 3164-3171.
-
(2000)
Journal of Clinical Oncology
, vol.18
, pp. 3164-3171
-
-
Kurata, T.1
Shimada, Y.2
Tamura, T.3
Yamamoto, N.4
Hyodo, I.5
Saeki, T.6
Takashima, S.7
Fujiwara, K.8
Wakasugi, H.9
Kashimura, M.10
-
274
-
-
4244166119
-
Pharmacokinetics of a new taxoid (RPR 109881A): comparison of five different administration schedules
-
Vernillet, L., Semiond, D., Vergniol, J., Pasquier, O., Dieras, V., Marty, M., Sessa, C., Gelmon, K., Latreille, J., Pazdur, R., and Besenval, M. (1998) Pharmacokinetics of a new taxoid (RPR 109881A): comparison of five different administration schedules. Proceedings: American Society of Clinical Oncology, 16, a749.
-
(1998)
Proceedings: American Society of Clinical Oncology
, vol.16
, pp. a749
-
-
Vernillet, L.1
Semiond, D.2
Vergniol, J.3
Pasquier, O.4
Dieras, V.5
Marty, M.6
Sessa, C.7
Gelmon, K.8
Latreille, J.9
Pazdur, R.10
Besenval, M.11
-
275
-
-
1242290108
-
A multicentre, non randomized phase II study with RPR 109881A in metastatic breast cancer (MBC) patients (pts)
-
Abstract 565
-
Dieras, V., Limantani, S., Lortholary, A., Tubiana-Hulin, M., Ferrero, J.-M., Minckwitz, F.V., Valero, V., Dreiling, L., Besenval, M., and Pouillart, P. (2003) A multicentre, non randomized phase II study with RPR 109881A in metastatic breast cancer (MBC) patients (pts). Proceedings: American Society of Clinical Oncology, 22, Abstract 565.
-
(2003)
Proceedings: American Society of Clinical Oncology
, vol.22
-
-
Dieras, V.1
Limantani, S.2
Lortholary, A.3
Tubiana-hulin, M.4
Ferrero, J.-M.5
Minckwitz, F.V.6
Valero, V.7
Dreiling, L.8
Besenval, M.9
Pouillart, P.10
-
276
-
-
46249085475
-
Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy
-
Dieras, V., Limentani, S., Romieu, G., Tubiana-Huli, M., Lortholary, A., Kaufman, P., Girre, V., Besenval, M., and Valero, V. (2008) Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy. Annals of Oncology, 19, 1255-1260.
-
(2008)
Annals of Oncology
, vol.19
, pp. 1255-1260
-
-
Dieras, V.1
Limentani, S.2
Romieu, G.3
Tubiana-huli, M.4
Lortholary, A.5
Kaufman, P.6
Girre, V.7
Besenval, M.8
Valero, V.9
-
277
-
-
59149102029
-
Larotaxel (L) in combination with trastuzumab in patients with HER2{thorn} metastatic breast cancer (MBC): interim analysis of an open phase II label study
-
Dieras, V., Viens, P., Veyret, C., Romieu, G., Awada, A., Lidbrink, E., Bonnefoi, H., Mery-Mignard, D., Dalenc, F., and Roche, H. (2008) Larotaxel (L) in combination with trastuzumab in patients with HER2{thorn} metastatic breast cancer (MBC): interim analysis of an open phase II label study. Journal of Clinical Oncology, 26, 1070.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 1070
-
-
Dieras, V.1
Viens, P.2
Veyret, C.3
Romieu, G.4
Awada, A.5
Lidbrink, E.6
Bonnefoi, H.7
Mery-mignard, D.8
Dalenc, F.9
Roche, H.10
-
278
-
-
58149140537
-
Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIB or stage IV non-small cell lung cancer
-
Zatloukal, P., Gervais, R., Vansteenkiste, J., Bosquee, L., Sessa, C., Brain, E., Dansin, E., Urban, T., Dohollou, N., Besenval, M., and Quoix, E. (2008) Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIB or stage IV non-small cell lung cancer. Journal of Thoracic Oncology, 3, 894-901.
-
(2008)
Journal of Thoracic Oncology
, vol.3
, pp. 894-901
-
-
Zatloukal, P.1
Gervais, R.2
Vansteenkiste, J.3
Bosquee, L.4
Sessa, C.5
Brain, E.6
Dansin, E.7
Urban, T.8
Dohollou, N.9
Besenval, M.10
Quoix, E.11
-
279
-
-
71449088216
-
A phase I study of larotaxel (XRP9881) administered in combination with carboplatin in chemotherapy-naïve patients with stage IIIB or stage IV non-small cell lung cancer
-
Robert, F., Harper, K., Ackerman, J., and Gupta, S. (2010) A phase I study of larotaxel (XRP9881) administered in combination with carboplatin in chemotherapy-naïve patients with stage IIIB or stage IV non-small cell lung cancer. Cancer Chemotherapy and Pharmacology, 65, 227-234.
-
(2010)
Cancer Chemotherapy and Pharmacology
, vol.65
, pp. 227-234
-
-
Robert, F.1
Harper, K.2
Ackerman, J.3
Gupta, S.4
-
280
-
-
1842843197
-
Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 598862) and tRA96023
-
Minderman, H., Brooks, T., Loughlin, K., Ojima, I., Bernacki, R., and Baer, M. (2004) Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 598862) and tRA96023. Cancer Chemotherapy and Pharmacology, 53, 363-369.
-
(2004)
Cancer Chemotherapy and Pharmacology
, vol.53
, pp. 363-369
-
-
Minderman, H.1
Brooks, T.2
Loughlin, K.3
Ojima, I.4
Bernacki, R.5
Baer, M.6
-
281
-
-
20344370349
-
Phase I and pharmacokinetic study of a novel taxane BAY-59-8862
-
Creaven, P., Eckhardt, S., Hamm, J., Schwartz, G., Sutton, J., Kaidbey, J., Lathia, C., Bernacki, R., and Ramnath, N. (2002) Phase I and pharmacokinetic study of a novel taxane BAY-59-8862. Proceedings: American Society of Clinical Oncology, 21, a100.
-
(2002)
Proceedings: American Society of Clinical Oncology
, vol.21
, pp. a100
-
-
Creaven, P.1
Eckhardt, S.2
Hamm, J.3
Schwartz, G.4
Sutton, J.5
Kaidbey, J.6
Lathia, C.7
Bernacki, R.8
Ramnath, N.9
-
282
-
-
9744268442
-
A phase I and pharmacokinetic study of a novel taxane BAY 59-8862 with a weekly schedule
-
Laurence, V., Pierga, J.-Y., Beuzeboc, P., Piperno-Neumann, S., Landon, F., Grange, V., Barouki, F., Brendel, E., Schwartz, B., and Dieras, V. (2003) A phase I and pharmacokinetic study of a novel taxane BAY 59-8862 with a weekly schedule. Proceedings: American Society of Clinical Oncology, 22, a647.
-
(2003)
Proceedings: American Society of Clinical Oncology
, vol.22
, pp. a647
-
-
Laurence, V.1
Pierga, J.-Y.2
Beuzeboc, P.3
Piperno-neumann, S.4
Landon, F.5
Grange, V.6
Barouki, F.7
Brendel, E.8
Schwartz, B.9
Dieras, V.10
-
283
-
-
84867428493
-
An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59-8862) in patients with taxane-resistant non-small cell lung cancer
-
Gurtler, J., Pawel, J., Spiridonidis, C., Grossi, F., Larriba, J., Moscovici, M., Markovitz, E., Voliotis, D., and Gottfried, M. (2004) An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59-8862) in patients with taxane-resistant non-small cell lung cancer. Journal of Clinical Oncology, 22, s7136.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. s7136
-
-
Gurtler, J.1
Pawel, J.2
Spiridonidis, C.3
Grossi, F.4
Larriba, J.5
Moscovici, M.6
Markovitz, E.7
Voliotis, D.8
Gottfried, M.9
-
284
-
-
59149092286
-
Phase II study of ortataxel in taxane-resistant breast cancer
-
Beer, M., Lenaz, L., and Amadori, D. (2008) Phase II study of ortataxel in taxane-resistant breast cancer. Journal of Clinical Oncology, 26, 1066.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 1066
-
-
Beer, M.1
Lenaz, L.2
Amadori, D.3
-
285
-
-
18444380509
-
Phase I and pharmacokinetics (PK) of DJ-927, an oral taxane, in patients (pts) with advanced cancers
-
Syed, S., Beeram, M., Takimoto, C., Jakubowitz, J., Kimura, M., Ducharme, M., Gadgeel, S., Jager, R.D., Rowinsky, E., and Lorusso, P. (2004) Phase I and pharmacokinetics (PK) of DJ-927, an oral taxane, in patients (pts) with advanced cancers. Journal of Clinical Oncology, 22, s2028.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. s2028
-
-
Syed, S.1
Beeram, M.2
Takimoto, C.3
Jakubowitz, J.4
Kimura, M.5
Ducharme, M.6
Gadgeel, S.7
Jager, R.D.8
Rowinsky, E.9
Lorusso, P.10
-
286
-
-
37749009044
-
A phase II study of DJ-927 as second-line therapy in patients (pts) with advanced gastric cancer (GC) who have failed a 5-FU non taxane based regimen
-
Evans, T., Dobrila, R., Berardi, R., Sumpter, K., Wall, L., Oyama, R., and Anthoney, D. (2006) A phase II study of DJ-927 as second-line therapy in patients (pts) with advanced gastric cancer (GC) who have failed a 5-FU non taxane based regimen. Journal of Clinical Oncology, 24, s4081.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. s4081
-
-
Evans, T.1
Dobrila, R.2
Berardi, R.3
Sumpter, K.4
Wall, L.5
Oyama, R.6
Anthoney, D.7
-
287
-
-
33646236205
-
Phase II trial of DJ-927 as a second-line treatment for colorectal cancer demonstrates objective responses
-
Rhee, J., Lee, F., Saif, M., Ardalan, B., Wolff, R., Eng, C., Bogaard, K., Cheverton, P., Kimura, M., Danna, M., and Hoff, P. (2005) Phase II trial of DJ-927 as a second-line treatment for colorectal cancer demonstrates objective responses. Journal of Clinical Oncology, 23, s3654.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. s3654
-
-
Rhee, J.1
Lee, F.2
Saif, M.3
Ardalan, B.4
Wolff, R.5
Eng, C.6
Bogaard, K.7
Cheverton, P.8
Kimura, M.9
Danna, M.10
Hoff, P.11
-
288
-
-
33845628267
-
Phase II trial of DJ-927, an oral tubulin depolymerization inhibitor, in the treatment of metastatic colorectal cancer
-
Moore, M., Jones, C., Harker, G., Lee, F., Ardalan, B., Saif, M., Hoff, P., Coomes, J., Rollins, C., and Felt, K. (2006) Phase II trial of DJ-927, an oral tubulin depolymerization inhibitor, in the treatment of metastatic colorectal cancer. Journal of Clinical Oncology, 24, s3591.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. s3591
-
-
Moore, M.1
Jones, C.2
Harker, G.3
Lee, F.4
Ardalan, B.5
Saif, M.6
Hoff, P.7
Coomes, J.8
Rollins, C.9
Felt, K.10
-
289
-
-
33845617558
-
Drug evaluation: tesetaxel: an oral semisynthetic taxane derivative
-
Roche, M., Kyriakou, H., and Seiden, M. (2006) Drug evaluation: tesetaxel: an oral semisynthetic taxane derivative. Current Opinion in Investigational Drugs, 7, 1092-1099.
-
(2006)
Current Opinion in Investigational Drugs
, vol.7
, pp. 1092-1099
-
-
Roche, M.1
Kyriakou, H.2
Seiden, M.3
-
290
-
-
50349093533
-
Phase I/II study of a 3 weekly oral taxane (DJ-927) in patients with recurrent, advanced non-small cell lung cancer
-
Baas, P., Szczesna, A., Albert, I., Milanowski, J., Juhasz, E., Sztancsik, Z., Pawel, J.V., Oyama, R., and Burgers, S. (2008) Phase I/II study of a 3 weekly oral taxane (DJ-927) in patients with recurrent, advanced non-small cell lung cancer. Journal of Thoracic Oncology, 3, 745-750.
-
(2008)
Journal of Thoracic Oncology
, vol.3
, pp. 745-750
-
-
Baas, P.1
Szczesna, A.2
Albert, I.3
Milanowski, J.4
Juhasz, E.5
Sztancsik, Z.6
Pawel, J.V.7
Oyama, R.8
Burgers, S.9
-
291
-
-
84871215302
-
Phase I dose-ranging, pharmacokinetic (PK) study of tesetaxel, a novel orally active tubulin-binding agent
-
Beeram, M., Papadopoulos, K., Patnaik, A., Qureshi, A., and Tolcher, A. (2010) Phase I dose-ranging, pharmacokinetic (PK) study of tesetaxel, a novel orally active tubulin-binding agent. Journal of Clinical Oncology, 28, ae13075.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. ae13075
-
-
Beeram, M.1
Papadopoulos, K.2
Patnaik, A.3
Qureshi, A.4
Tolcher, A.5
-
292
-
-
84926457684
-
An intersubject dose-escalation study of tesetaxel administered orally once every 3 weeks and once weekly for 3 consecutive weeks in patients with advanced or metastatic solid tumors
-
Beeram, M., Novick, S., Qureshi, A., Patnaik, A., Papadopoulos, K., and Tolcher, A. (2010) An intersubject dose-escalation study of tesetaxel administered orally once every 3 weeks and once weekly for 3 consecutive weeks in patients with advanced or metastatic solid tumors. Journal of Clinical Oncology, 28, 159.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 159
-
-
Beeram, M.1
Novick, S.2
Qureshi, A.3
Patnaik, A.4
Papadopoulos, K.5
Tolcher, A.6
-
293
-
-
82455162574
-
Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I dose-escalation study in patients with advanced solid tumors
-
Saif, M., Sarantopoulos, J., Patnaik, A., Tolcher, A., Takimoto, C., and Beeram, M. (2011) Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I dose-escalation study in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology, 68, 1565-1573.
-
(2011)
Cancer Chemotherapy and Pharmacology
, vol.68
, pp. 1565-1573
-
-
Saif, M.1
Sarantopoulos, J.2
Patnaik, A.3
Tolcher, A.4
Takimoto, C.5
Beeram, M.6
-
294
-
-
0642349139
-
MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo
-
Sampath, D., Discafani, C., Loganzo, F., Beyer, B., Liu, H., Tan, X., Musto, S., Annable, T., Gallagher, P., Rios, C., and Greenberger, L. (2000) MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo. Molecular Cancer Therapeutics, 2, 873-884.
-
(2000)
Molecular Cancer Therapeutics
, vol.2
, pp. 873-884
-
-
Sampath, D.1
Discafani, C.2
Loganzo, F.3
Beyer, B.4
Liu, H.5
Tan, X.6
Musto, S.7
Annable, T.8
Gallagher, P.9
Rios, C.10
Greenberger, L.11
-
295
-
-
37249024710
-
A phase II study of milataxel: a novel taxane analogue in previously treated patients with advanced colorectal cancer
-
Ramanathan, R., Picus, J., Raftopoulos, H., Bernard, S., Lockhart, A., Frenette, G., Macdonald, J., Melin, S., Berg, D., Brescia, F., Hochster, H., and Cohn, A. (2008) A phase II study of milataxel: a novel taxane analogue in previously treated patients with advanced colorectal cancer. Cancer Chemotherapy and Pharmacology, 61, 435-438.
-
(2008)
Cancer Chemotherapy and Pharmacology
, vol.61
, pp. 435-438
-
-
Ramanathan, R.1
Picus, J.2
Raftopoulos, H.3
Bernard, S.4
Lockhart, A.5
Frenette, G.6
Macdonald, J.7
Melin, S.8
Berg, D.9
Brescia, F.10
Hochster, H.11
Cohn, A.12
-
296
-
-
37248998834
-
A phase II study of intravenous (iv) Milataxel (M) for the treatment of non-small cell lung cancer (NSCLC) refractory to platinum-based therapy
-
Mekhail, T., Serwatowski, P., Dudek, A., Belani, C., Jankowska, R., Pandya, K., Arnold, S., Brahmer, J., Gitlitz, B., and Govindan, R. (2006) A phase II study of intravenous (iv) Milataxel (M) for the treatment of non-small cell lung cancer (NSCLC) refractory to platinum-based therapy. Journal of Clinical Oncology, 24, s7089.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. s7089
-
-
Mekhail, T.1
Serwatowski, P.2
Dudek, A.3
Belani, C.4
Jankowska, R.5
Pandya, K.6
Arnold, S.7
Brahmer, J.8
Gitlitz, B.9
Govindan, R.10
-
297
-
-
34248335926
-
Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors
-
Lockhart, A., Bukowski, R., Rothenberg, M., Wang, K., Cooper, W., Grover, J., Appleman, L., Mayer, R., Shapiro, M., and Zhu, A. (2007) Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors. Cancer Chemotherapy and Pharmacology, 60, 203-209.
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, pp. 203-209
-
-
Lockhart, A.1
Bukowski, R.2
Rothenberg, M.3
Wang, K.4
Cooper, W.5
Grover, J.6
Appleman, L.7
Mayer, R.8
Shapiro, M.9
Zhu, A.10
-
298
-
-
0028306775
-
Taxuspines A-C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells
-
Kobayashi, J., Ogiwara, A., Hosoyama, H., Shigemori, H., Yoshida, N., Sasaki, T., Li, Y., Iwasaki, S., Naito, M., and Tsuruo, T. (1994) Taxuspines A-C, new taxoids from Japanese yew Taxus cuspidata inhibiting drug transport activity of P-glycoprotein in multidrug-resistant cells. Tetrahedron, 50, 7401-7416.
-
(1994)
Tetrahedron
, vol.50
, pp. 7401-7416
-
-
Kobayashi, J.1
Ogiwara, A.2
Hosoyama, H.3
Shigemori, H.4
Yoshida, N.5
Sasaki, T.6
Li, Y.7
Iwasaki, S.8
Naito, M.9
Tsuruo, T.10
-
299
-
-
0033535076
-
Modulation of multidrug resistance in tumor cells by taxinine derivative
-
Hosoyama, H., Shigemori, H., Tomida, A., Tsuruo, T., and Kobayashi, J. (1999) Modulation of multidrug resistance in tumor cells by taxinine derivative. Bioorganic & Medicinal Chemistry Letters, 9, 389-394.
-
(1999)
Bioorganic & Medicinal Chemistry Letters
, vol.9
, pp. 389-394
-
-
Hosoyama, H.1
Shigemori, H.2
Tomida, A.3
Tsuruo, T.4
Kobayashi, J.5
-
300
-
-
84926451065
-
Discovery and development of new taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells
-
Ojima, I., Bounaud, P.-Y., Pera, P., and Bernacki, R. (1998) Discovery and development of new taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells. Annals of Oncology, 9, s557.
-
(1998)
Annals of Oncology
, vol.9
, pp. s557
-
-
Ojima, I.1
Bounaud, P.-Y.2
Pera, P.3
Bernacki, R.4
-
301
-
-
0032548461
-
New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells
-
Ojima, I., Bounaud, P.-Y., Takeuchi, C., Pera, P., and Bernacki, R. (1998) New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells. Bioorganic & Medicinal Chemistry Letters, 8, 189-194.
-
(1998)
Bioorganic & Medicinal Chemistry Letters
, vol.8
, pp. 189-194
-
-
Ojima, I.1
Bounaud, P.-Y.2
Takeuchi, C.3
Pera, P.4
Bernacki, R.5
-
302
-
-
20144384731
-
Design, synthesis and SAR of novel taxane-based multi-drug resistance reversal agents
-
Ojima, I., Borella, C., Wu, X., Bounaud, P.-Y., Fumero, C., Sturm, M., Miller, M., Chakravarty, S., Chen, J., Huang, Q., Pera, P., Brooks, T., Baer, M., and Bernacki, R. (2005) Design, synthesis and SAR of novel taxane-based multi-drug resistance reversal agents. Journal of Medicinal Chemistry, 48, 2218-2228.
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, pp. 2218-2228
-
-
Ojima, I.1
Borella, C.2
Wu, X.3
Bounaud, P.-Y.4
Fumero, C.5
Sturm, M.6
Miller, M.7
Chakravarty, S.8
Chen, J.9
Huang, Q.10
Pera, P.11
Brooks, T.12
Baer, M.13
Bernacki, R.14
-
303
-
-
3242717109
-
Taxane-based reversal agent modulation of P-glycoprotein-, multidrug resistance protein- and breast cancer resistance protein-mediated drug transport
-
Brooks, T., Minderman, H., O'Loughlin, K., Ojima, I., Baer, M., and Bernacki, R. (2003) Taxane-based reversal agent modulation of P-glycoprotein-, multidrug resistance protein- and breast cancer resistance protein-mediated drug transport. Molecular Cancer Therapeutics, 2, 1195-1205.
-
(2003)
Molecular Cancer Therapeutics
, vol.2
, pp. 1195-1205
-
-
Brooks, T.1
Minderman, H.2
O'Loughlin, K.3
Ojima, I.4
Baer, M.5
Bernacki, R.6
-
304
-
-
2442446415
-
Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators
-
Brooks, T., Kennedy, D., Gruol, D., Ojima, I., Baer, M., and Bernacki, R. (2004) Structure-activity analysis of taxane-based broad-spectrum multidrug resistance modulators. Anticancer Research, 24, 409-415.
-
(2004)
Anticancer Research
, vol.24
, pp. 409-415
-
-
Brooks, T.1
Kennedy, D.2
Gruol, D.3
Ojima, I.4
Baer, M.5
Bernacki, R.6
-
305
-
-
9744264044
-
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias
-
Benderra, Z., Gaussat, A.-M., Sayada, L., Perrot, J.-Y., Chaoui, D., Marie, J.-P., and Legrand, O. (2004) Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias. Clinical Cancer Research, 10, 7896-7902.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 7896-7902
-
-
Benderra, Z.1
Gaussat, A.-M.2
Sayada, L.3
Perrot, J.-Y.4
Chaoui, D.5
Marie, J.-P.6
Legrand, O.7
-
306
-
-
0034954447
-
The use of a novel taxane-based P-glycoprotein inhibitors to identify mutations altering the protein's interaction with paclitaxel
-
Gruol, D., Bernd, J., Phippard, A., Ojima, I., and Bernacki, R. (2001) The use of a novel taxane-based P-glycoprotein inhibitors to identify mutations altering the protein's interaction with paclitaxel. Molecular Pharmacology, 60, 104-113.
-
(2001)
Molecular Pharmacology
, vol.60
, pp. 104-113
-
-
Gruol, D.1
Bernd, J.2
Phippard, A.3
Ojima, I.4
Bernacki, R.5
-
307
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
Belotti, D., Vergani, V., Drudis, T., Borsotti, P., Pitelli, M., Viale, M., Giavazzi, R., and Taraboletti, G. (1996) The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clinical Cancer Research, 2, 1843-1849.
-
(1996)
Clinical Cancer Research
, vol.2
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
Borsotti, P.4
Pitelli, M.5
Viale, M.6
Giavazzi, R.7
Taraboletti, G.8
-
308
-
-
0036554920
-
Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative
-
Taraboletti, G., Micheletti, G., Rieppi, M., Poli, M., Turatto, M., Rossi, C., Borsotti, P., Roccabianca, P., Scanziani, E., Nicoletti, M., Bombardelli, E., Morazzoni, P., Riva, A., and Giavazzi, R. (2002) Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative. Clinical Cancer Research, 8, 1182-1188.
-
(2002)
Clinical Cancer Research
, vol.8
, pp. 1182-1188
-
-
Taraboletti, G.1
Micheletti, G.2
Rieppi, M.3
Poli, M.4
Turatto, M.5
Rossi, C.6
Borsotti, P.7
Roccabianca, P.8
Scanziani, E.9
Nicoletti, M.10
Bombardelli, E.11
Morazzoni, P.12
Riva, A.13
Giavazzi, R.14
-
309
-
-
84864346913
-
Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes
-
Otová, B., Ojima, I., Václaviková, R., Hrdý, J., Ehrlichová, M., Souček, P., Vobořilová, J., Němcová, V., Zanardi, I., Horský, S., Kovář, J., and Gut, I. (2012) Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes. Investigational New Drugs, 30, 991-1002.
-
(2012)
Investigational New Drugs
, vol.30
, pp. 991-1002
-
-
Otová, B.1
Ojima, I.2
Václaviková, R.3
Hrdý, J.4
Ehrlichová, M.5
Souček, P.6
Vobořilová, J.7
Němcová, V.8
Zanardi, I.9
Horský, S.10
Kovář, J.11
Gut, I.12
-
310
-
-
65249123159
-
Antivascular actions of microtubule-binding drugs
-
Schwartz, E. (2009) Antivascular actions of microtubule-binding drugs. Clinical Cancer Research, 15, 2594-2601.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 2594-2601
-
-
Schwartz, E.1
-
311
-
-
2342455797
-
Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in paclitaxel-resistant human ovarian tumour xenograft
-
Petrangolini, G., Cassinelli, G., Pratesi, G., Tortoreto, M., Favini, E., Supinio, R., Lanzi, C., Belluco, S., and Zunino, F. (2004) Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in paclitaxel-resistant human ovarian tumour xenograft. British Journal of Cancer, 90, 1464-1468.
-
(2004)
British Journal of Cancer
, vol.90
, pp. 1464-1468
-
-
Petrangolini, G.1
Cassinelli, G.2
Pratesi, G.3
Tortoreto, M.4
Favini, E.5
Supinio, R.6
Lanzi, C.7
Belluco, S.8
Zunino, F.9
-
312
-
-
33751570159
-
Pharmacokinetics and metabolism in mice of IDN 5390 (13-)N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral C-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors
-
Frapolli, R., Marangon, E., Zaffaroni, M., Colombo, T., Falcioni, C., Bagnati, R., Simone, M., D'Incalci, M., Manzotti, C., Fontana, G., Morazzoni, P., and Zucchetti, M. (2006) Pharmacokinetics and metabolism in mice of IDN 5390 (13-)N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral C-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors. Drug Metabolism and Disposition, 34, 2028-2035.
-
(2006)
Drug Metabolism and Disposition
, vol.34
, pp. 2028-2035
-
-
Frapolli, R.1
Marangon, E.2
Zaffaroni, M.3
Colombo, T.4
Falcioni, C.5
Bagnati, R.6
Simone, M.7
D'Incalci, M.8
Manzotti, C.9
Fontana, G.10
Morazzoni, P.11
Zucchetti, M.12
-
313
-
-
0026686943
-
Tuberculosis: commentary on a reemergent killer
-
Bloom, B.R. and Murray, C.J. (1992) Tuberculosis: commentary on a reemergent killer. Science, 257, 1055-1064.
-
(1992)
Science
, vol.257
, pp. 1055-1064
-
-
Bloom, B.R.1
Murray, C.J.2
-
314
-
-
77956053743
-
Discovery of anti-TB agents that target the cell-division protein FtsZ
-
Kumar, K., Awasthi, D., Berger, W.T., Tonge, P., Slayden, R., and Ojima, I. (2010) Discovery of anti-TB agents that target the cell-division protein FtsZ. Future Medicinal Chemistry, 2, 1305-1323.
-
(2010)
Future Medicinal Chemistry
, vol.2
, pp. 1305-1323
-
-
Kumar, K.1
Awasthi, D.2
Berger, W.T.3
Tonge, P.4
Slayden, R.5
Ojima, I.6
-
315
-
-
0242693139
-
Assembly dynamics of the bacterial cell division protein FtsZ: poised at the edge of stability
-
Romberg, L. and Levin, P.A. (2003) Assembly dynamics of the bacterial cell division protein FtsZ: poised at the edge of stability. Annual Review of Microbiology, 57, 125-154.
-
(2003)
Annual Review of Microbiology
, vol.57
, pp. 125-154
-
-
Romberg, L.1
Levin, P.A.2
-
316
-
-
0026705484
-
The essential bacterial cell-division protein FtsZ is a GTPase
-
DeBoer, P.C.R. and Rotherfield, L. (1992) The essential bacterial cell-division protein FtsZ is a GTPase. Nature, 359, 254-256.
-
(1992)
Nature
, vol.359
, pp. 254-256
-
-
DeBoer, P.C.R.1
Rotherfield, L.2
-
317
-
-
0029852223
-
Tubulin secondary structure analysis, limited proteolysis sites and homology to FtsZ
-
dePereda, J.M., Leynadier, D., Evangelio, J.A., Chacon, P., and Andreu, J.M. (1996) Tubulin secondary structure analysis, limited proteolysis sites and homology to FtsZ. Biochemistry, 35, 14203-14215.
-
(1996)
Biochemistry
, vol.35
, pp. 14203-14215
-
-
dePereda, J.M.1
Leynadier, D.2
Evangelio, J.A.3
Chacon, P.4
Andreu, J.M.5
-
318
-
-
31544472652
-
Targeting FtsZ for anti-tuberculosis drug discovery: noncytotoxic taxanes as novel anti-tuberculosis agents
-
Huang, Q., Kirikae, F., Kirikae, T., Pepe, A., Slayden, R.A., Tonge, P.J., and Ojima, I. (2006) Targeting FtsZ for anti-tuberculosis drug discovery: noncytotoxic taxanes as novel anti-tuberculosis agents. Journal of Medicinal Chemistry, 49, 463-466.
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, pp. 463-466
-
-
Huang, Q.1
Kirikae, F.2
Kirikae, T.3
Pepe, A.4
Slayden, R.A.5
Tonge, P.J.6
Ojima, I.7
|