-
1
-
-
0035899331
-
Integrin signalling inhibits paclitaxel-induced apoptosis in breast cancer cells
-
Aoudjit F, Vuori K (2001) Integrin signalling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 20:4995-5004
-
(2001)
Oncogene
, vol.20
, pp. 4995-5004
-
-
Aoudjit, F.1
Vuori, K.2
-
2
-
-
59149092286
-
Phase II study of ortataxel in taxane-resistant breast cancer
-
abstract
-
Beer M, Lenaz L, Amador D (2008) Phase II study of ortataxel in taxane-resistant breast cancer. J Clin Oncol 26(20 supplement): 1066, abstract
-
(2008)
J Clin Oncol
, vol.26
, Issue.20 SUPPL.
, pp. 1066
-
-
Beer, M.1
Lenaz, L.2
Amador, D.3
-
3
-
-
41849106072
-
Cellular mechanisms of resistance to anthracyclines and taxanes in cancer: Intrinsic and acquired
-
quiz S39
-
Chien AJ, Moasser MM (2008) Cellular mechanisms of resistance to anthracyclines and taxanes in cancer: intrinsic and acquired. Semin Oncol 35(2 Suppl 2):S1-S14, quiz S39
-
(2008)
Semin Oncol
, vol.35
, Issue.2 SUPPL. 2
-
-
Chien, A.J.1
Moasser, M.M.2
-
4
-
-
0035111779
-
Taxanes in combined modality therapy for solid tumors
-
Choy H (2001) Taxanes in combined modality therapy for solid tumors. Review. Crit Rev Oncol Hematol 37:237-247
-
(2001)
Review. Crit Rev Oncol Hematol
, vol.37
, pp. 237-247
-
-
Choy, H.1
-
5
-
-
26244441166
-
Transport and cytotoxicity of paclitaxel, docetaxel and three novel taxanes in human breast cancer cells
-
Ehrlichová M, Václavíková R, Ojima I et al (2005) Transport and cytotoxicity of paclitaxel, docetaxel and three novel taxanes in human breast cancer cells. N-S Arch Pharmacol 372:95-105
-
(2005)
N-S Arch Pharmacol
, vol.372
, pp. 95-105
-
-
Ehrlichová, M.1
Václavíková, R.2
Ojima, I.3
-
6
-
-
0034543235
-
Antitumour activity of novel taxanes act at the same time as cytotoxic agents and Pglycoprotein inhibitors
-
Ferlini C, Distefano M, Pignatelli F, Lin S, Riva A, Bombardelli E, Mancuso S, Ojima I, Scambia G (2000) Antitumour activity of novel taxanes act at the same time as cytotoxic agents and Pglycoprotein inhibitors. Br J Cancer 83:1762-1768
-
(2000)
Br J Cancer
, vol.83
, pp. 1762-1768
-
-
Ferlini, C.1
Distefano, M.2
Pignatelli, F.3
Lin, S.4
Riva, A.5
Bombardelli, E.6
Mancuso, S.7
Ojima, I.8
Scambia, G.9
-
7
-
-
65249157992
-
Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity
-
Freedman H, Huzil JT, Luchko T, Luduena RF, Tuzsynski JA (2009) Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity. J Chem Inf Model 49:424-436
-
(2009)
J Chem Inf Model
, vol.49
, pp. 424-436
-
-
Freedman, H.1
Huzil, J.T.2
Luchko, T.3
Luduena, R.F.4
Tuzsynski, J.A.5
-
8
-
-
41949119102
-
Paclitaxel and docetaxel resistance: Molecular mechanisms and development of new generation taxanes
-
Galletti E, Magnani M, Renzulli ML, Botta M (2007) Paclitaxel and docetaxel resistance: molecular mechanisms and development of new generation taxanes. Chem Med Chem 7:920-942
-
(2007)
Chem Med Chem
, vol.7
, pp. 920-942
-
-
Galletti, E.1
Magnani, M.2
Renzulli, M.L.3
Botta, M.4
-
9
-
-
0034633805
-
Simple and sensitive high-performance liquid chromatography. Method for determination of docetaxel in human plasma and urine
-
Garg MB, Ackland SP (2000) Simple and sensitive high-performance liquid chromatography. Method for determination of docetaxel in human plasma and urine. J Chromatog B 748:383-388
-
(2000)
J Chromatog B
, vol.748
, pp. 383-388
-
-
Garg, M.B.1
Ackland, S.P.2
-
10
-
-
0033764635
-
Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: Effects of concentration, time and cytochrome P450-catalyzed metabolism
-
Gut I, Danielova V, Holubova J, Soucek P, Kluckova H (2000) Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: effects of concentration, time and cytochrome P450-catalyzed metabolism. Arch Toxicol 74:437-446
-
(2000)
Arch Toxicol
, vol.74
, pp. 437-446
-
-
Gut, I.1
Danielova, V.2
Holubova, J.3
Soucek, P.4
Kluckova, H.5
-
11
-
-
33748711014
-
Metabolism of new generation taxanes in human, pig, minipig and rat liver microsomes
-
Gut I, Václavíková R, Simek P, Ojima I,Horsky S, Soucek P, Kondrova E (2006) Metabolism of new generation taxanes in human, pig, minipig and rat liver microsomes. Xenobiotica 36:772-792
-
(2006)
Xenobiotica
, vol.36
, pp. 772-792
-
-
Gut, I.1
Václavíková, R.2
Simek, P.3
Ojima, I.4
Horsky, S.5
Soucek, P.6
Kondrova, E.7
-
13
-
-
68549115311
-
Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells
-
Kovář J, Ehrlichová M, Šmejkalová B, Zanardi I, Ojima I, Gut I (2009) Comparison of cell death-inducing effect of novel taxane SB-T-1216 and paclitaxel in breast cancer cells. Anticancer Res 29:2951-2960
-
(2009)
Anticancer Res
, vol.29
, pp. 2951-2960
-
-
Kovář, J.1
Ehrlichová, M.2
Šmejkalová, B.3
Zanardi, I.4
Ojima, I.5
Gut, I.6
-
14
-
-
0035756986
-
Chemistry and chemical biology of taxane anticancer agents
-
Miller ML, Ojima I (2001) Chemistry and chemical biology of taxane anticancer agents. Chem Rec 1:195-211
-
(2001)
Chem Rec
, vol.1
, pp. 195-211
-
-
Miller, M.L.1
Ojima, I.2
-
15
-
-
0037334157
-
Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole
-
Monks A, Harris E, Hose C, Connelly J, Sausville EA (2003) Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3- methylphenyl)-5-fluorobenzothiazole. Mol Pharmacol 63:766-772
-
(2003)
Mol Pharmacol
, vol.63
, pp. 766-772
-
-
Monks, A.1
Harris, E.2
Hose, C.3
Connelly, J.4
Sausville, E.A.5
-
16
-
-
10144251769
-
Synthesis and structure-activity relationships of the second-generation antitumor taxoids: Exceptional activity against drug-resistant cancer cells
-
Ojima I, Slater JC, Michaud E, Kuduk SD, Bounaud PY, Vrignaud P, Bissery MC, Veith JM, Pera P, Bernacki RJ (1996) Synthesis and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells. J Med Chem 39:3889-3896
-
(1996)
J Med Chem
, vol.39
, pp. 3889-3896
-
-
Ojima, I.1
Slater, J.C.2
Michaud, E.3
Kuduk, S.D.4
Bounaud, P.Y.5
Vrignaud, P.6
Bissery, M.C.7
Veith, J.M.8
Pera, P.9
Bernacki, R.J.10
-
17
-
-
0031040149
-
The development and clinical utility of taxane class of antimicrotubule chemotherapy agents
-
Rowinsky EK (1997) The development and clinical utility of taxane class of antimicrotubule chemotherapy agents. Annu RevMed 48:353-374
-
(1997)
Annu RevMed
, vol.48
, pp. 353-374
-
-
Rowinsky, E.K.1
-
19
-
-
0019889058
-
Taxol assembles tubulin in the absence of exogenous guanosine 5′-triphosphate or microtubule-associated proteins
-
Schiff PB, Horwitz SB (1981) Taxol assembles tubulin in the absence of exogenous guanosine 5′-triphosphate or microtubule-associated proteins. Biochemistry 20:3247-3252
-
(1981)
Biochemistry
, vol.20
, pp. 3247-3252
-
-
Schiff, P.B.1
Horwitz, S.B.2
-
20
-
-
0141993644
-
The paclitaxelmetabolism in rat and human liver microsomes is inhibited by phenolic antioxidants
-
Václaviková R,Horsky S, Simek P, Gut I (2003) The paclitaxelmetabolism in rat and human liver microsomes is inhibited by phenolic antioxidants. Naunyn-Schmiedebergs Arch Pharmacol 368:200-209
-
(2003)
Naunyn-Schmiedebergs Arch Pharmacol
, vol.368
, pp. 200-209
-
-
Václaviková, R.1
Horsky, S.2
Simek, P.3
Gut, I.4
-
21
-
-
40049090206
-
Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1); Effects on its expression and clinicopathological characteristics in breast cancer patients
-
Václaviková R, Nordgard SH, Alnaes GIG, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P (2008) Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1); effects on its expression and clinicopathological characteristics in breast cancer patients. Pharmacogenetics Genom 18:263-273
-
(2008)
Pharmacogenetics Genom
, vol.18
, pp. 263-273
-
-
Václaviková, R.1
Nordgard, S.H.2
Alnaes, G.I.G.3
Hubackova, M.4
Kubala, E.5
Kodet, R.6
Mrhalova, M.7
Novotny, J.8
Gut, I.9
Kristensen, V.N.10
Soucek, P.11
-
22
-
-
79955608066
-
Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells
-
Vobořilová J, Němcová-Fürstová V, Neubauerová J, Ojima I, Zanardi I, Gut I, Kovář J (2011) Cell death induced by novel fluorinated taxanes in drug-sensitive and drug-resistant cancer cells. Invest New Drugs 29(3):411-423
-
(2011)
Invest New Drugs
, vol.29
, Issue.3
, pp. 411-423
-
-
Vobořilová, J.1
Němcová-Fürstová, V.2
Neubauerová, J.3
Ojima, I.4
Zanardi, I.5
Gut, I.6
Kovář, J.7
|