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The pipeline of new anticancer agents for breast cancer treatment in 2003
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0041503044
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A Phase II study of epothilone analog BMS-247550 in patients with metastatic breast cancer previously treated with an anthracycline
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A Phase II study of the epothilone B analog BMS-247550 in patients with taxane-resistant metastatic breast cancer
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Thomas, E.1
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0346706376
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Phase I dose-escalation trial evaluating the safety and tolerability of EPO906 plus capecitabine in patients with advanced cancer
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(Abstract 624)
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Van Oosterom AT, Dumez H, Calvert AH et al. Phase I dose-escalation trial evaluating the safety and tolerability of EPO906 plus capecitabine in patients with advanced cancer. Proc. Am. Soc. Clin. Oncol. 22 (2003) (Abstract 624).
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Van Oosterom, A.T.1
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0036848118
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Phase I and pharmacological study of the oral farnesyltransferase inhibitor SCH-66336 given once daily to patients with advanced solid tumors
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Awada A, Eskens FA, Piccart M et al. Phase I and pharmacological study of the oral farnesyltransferase inhibitor SCH-66336 given once daily to patients with advanced solid tumors. Eur. J. Cancer 38(17), 2272-2278, (2002).
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Phase I and pharmacokinetic study of the oral farnesyl transferase inhibitor SCH 66336 given twice daily to patients with advanced solid tumors
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Eskens FA, Awada A, Cutler DL et al. Phase I and pharmacokinetic study of the oral farnesyl transferase inhibitor SCH 66336 given twice daily to patients with advanced solid tumors. J. Clin. Oncol. 19(4), 1167-1175 (2001).
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Phase I and pharmacokinetic study of farnesyltransferase inhibitor R115777 in advanced cancer
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0000165438
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A Phase I, clinical and pharmacokinetic (PK) trial of the farnesyl transferase inhibitor (FTI) R115777 plus docetaxel: A promising combination in patients (pts) with solid tumors
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(Abstract 318)
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Piccart-Gebhart MJ, Branle F, de Valeriola D et al. A Phase I, clinical and pharmacokinetic (PK) trial of the farnesyl transferase inhibitor (FTI) R115777 plus docetaxel: a promising combination in patients (pts) with solid tumors. Proc. Am. Soc. Clin. Oncol. (2001) (Abstract 318).
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Piccart-Gebhart, M.J.1
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de Valeriola, D.3
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0041496773
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Final report of the Phase I clinical program of the novel raf kinase inhibitor BAY 43-9006 in patients with refractory solid tumors
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(Abstract 813)
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Strumberg D, Awada A, Piccart M. Final report of the Phase I clinical program of the novel raf kinase inhibitor BAY 43-9006 in patients with refractory solid tumors. Proc. Am. Soc. Clin. Oncol. 22 (2003) (Abstract 813).
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Strumberg, D.1
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Piccart, M.3
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11
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0013388868
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Final results of a clinical and pharmacokinetic (PK) Phase I study of the Raf kinase inhibitor BAY 43-9006 in refractory solid cancers: A promising antitumor agent
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(Abstract 162)
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Awada A, Hendlisz H, Gil T et al. Final results of a clinical and pharmacokinetic (PK) Phase I study of the Raf kinase inhibitor BAY 43-9006 in refractory solid cancers: a promising antitumor agent. Eur. J. Cancer 38(Suppl. 7), S52 (2002) (Abstract 162).
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Final results of a Phase I study of the Raf-1 kinase inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
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(Abstract 173)
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Hirte H, Moore M, Hotte S. Final results of a Phase I study of the Raf-1 kinase inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. Eur. J. Cancer 38 (Suppl. 7), S55 (2002) (Abstract 173).
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0042498542
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Phase I study of oral raf-1 kinase inhibitor BAY 43-9006 with gemcitabine in patients with advanced solid tumors
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(Abstract 828)
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Siu L, Awada A, Takimoto CH et al. Phase I study of oral raf-1 kinase inhibitor BAY 43-9006 with gemcitabine in patients with advanced solid tumors. Proc. Am. Soc. Clin. Oncol. 22 (2003) (Abstract 828).
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Siu, L.1
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The proteasome - An emerging therapeutic target in cancer
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A Phase II study of bortezomib in relapsed, refractory myeloma
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Richardson PG, Barlogie B, Berenson J et al. A Phase II study of bortezomib in relapsed, refractory myeloma. N. Engl. J. Med. 348(26), 2609-2617 (2003).
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0142139039
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Phase I study of bortezomib in combination with docetaxel in anthracycline-pretreated advanced breast cancer
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Albanell J, Baselga J, Guix M et al. Phase I study of bortezomib in combination with docetaxel in anthracycline-pretreated advanced breast cancer. Proc. Am. Soc. Clin. Oncol. 22 (2003) (Abstract 63).
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A randomized trial of bevacizumab, an antivascular endothelial growth factor antibody for metastatic renal cancer
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0002235290
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Phase III trial of capecitabine (Xeloda®) plus bevacizumab (Avastin™) versus capecitabine alone in women with metastatic breast cancer previously treated with an anthracycline and a taxane
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(Abstract 36)
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Miller K, Rugo H, Cobleigh M et al. Phase III trial of capecitabine (Xeloda®) plus bevacizumab (Avastin™) versus capecitabine alone in women with metastatic breast cancer previously treated with an anthracycline and a taxane. Breast Cancer Res. Treat. 76(Suppl. 1), S37 (2002) (Abstract 36).
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First results of a Phase I and pharmacokinetic study of SU011248, a novel oral anti-angiogenic agent, in patients with advanced solid tumors
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Phase I study of PTK787/ZK 222584 (PTK/ZK) in metastatic renal cell carcinoma
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George, D.1
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