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Volumn 8, Issue 5, 2003, Pages 411-424

The role of ABC transporters in clinical practice

Author keywords

ABC transporter; Cancer; Chemotherapy; Clinical trial; Multidrug resistance

Indexed keywords

ABC TRANSPORTER; AMIODARONE; ANTINEOPLASTIC AGENT; BIRICODAR; CISPLATIN; CYCLOSPORIN; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; GLYCOPROTEIN P; IFOSFAMIDE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PHENOTHIAZINE DERIVATIVE; PROTEIN INHIBITOR; QUINIDINE; TAMOXIFEN; TARIQUIDAR; UNCLASSIFIED DRUG; VALSPODAR; VERAPAMIL; VINCRISTINE; VINDESINE;

EID: 0141888537     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.8-5-411     Document Type: Review
Times cited : (703)

References (114)
  • 1
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-1042.
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 2
    • 0035868913 scopus 로고    scopus 로고
    • Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: Sobering results
    • Breathnach OS, Freidlin B, Conley B et al. Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results. J Clin Oncol 2001;19:1734-1742.
    • (2001) J Clin Oncol , vol.19 , pp. 1734-1742
    • Breathnach, O.S.1    Freidlin, B.2    Conley, B.3
  • 4
    • 0037045574 scopus 로고    scopus 로고
    • Resistance to targeted therapy in leukaemia
    • Griffin JD. Resistance to targeted therapy in leukaemia. Lancet 2002;359:458-459.
    • (2002) Lancet , vol.359 , pp. 458-459
    • Griffin, J.D.1
  • 5
    • 0036118297 scopus 로고    scopus 로고
    • Determinants of response and resistance to cytotoxics
    • Rosell R, Monzo M, Alberola V et al. Determinants of response and resistance to cytotoxics. Semin Oncol 2002;29(suppl 4):110-118.
    • (2002) Semin Oncol , vol.29 , Issue.SUPPL. 4 , pp. 110-118
    • Rosell, R.1    Monzo, M.2    Alberola, V.3
  • 6
    • 0031974420 scopus 로고    scopus 로고
    • Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins
    • Shen D, Pastan I, Gottesman MM. Cross-resistance to methotrexate and metals in human cisplatin-resistant cell lines results from a pleiotropic defect in accumulation of these compounds associated with reduced plasma membrane binding proteins. Cancer Res 1998;58:268-275.
    • (1998) Cancer Res , vol.58 , pp. 268-275
    • Shen, D.1    Pastan, I.2    Gottesman, M.M.3
  • 7
    • 0035240260 scopus 로고    scopus 로고
    • Apoptosis: Implications of basic research for clinical oncology
    • Tamm I, Schriever F, Dorken B. Apoptosis: implications of basic research for clinical oncology. Lancet Oncol 2001;2:33-42.
    • (2001) Lancet Oncol , vol.2 , pp. 33-42
    • Tamm, I.1    Schriever, F.2    Dorken, B.3
  • 8
    • 0029944106 scopus 로고    scopus 로고
    • Antitopoisomerase drug action and resistance
    • Nitiss JL, Beck WT. Antitopoisomerase drug action and resistance. Eur J Cancer 1996;32A:958-966.
    • (1996) Eur J Cancer , vol.32 A , pp. 958-966
    • Nitiss, J.L.1    Beck, W.T.2
  • 9
    • 0031939392 scopus 로고    scopus 로고
    • Glutathione-related mechanisms in cellular resistance to anticancer drugs
    • Zhang K, Mack P, Wong KP. Glutathione-related mechanisms in cellular resistance to anticancer drugs. Int J Oncol 1998;12:871-882.
    • (1998) Int J Oncol , vol.12 , pp. 871-882
    • Zhang, K.1    Mack, P.2    Wong, K.P.3
  • 10
    • 0008954320 scopus 로고
    • The induction of resistance to 4-amino-N10-methyl-pteroylglutaminic acid in a strain of transmitted mouse leukemia
    • Burchenal JH, Robinson E, Johnston SF et al. The induction of resistance to 4-amino-N10-methyl-pteroylglutaminic acid in a strain of transmitted mouse leukemia. Science 1950;111:116-117.
    • (1950) Science , vol.111 , pp. 116-117
    • Burchenal, J.H.1    Robinson, E.2    Johnston, S.F.3
  • 11
    • 0015893137 scopus 로고
    • Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells
    • Dano K. Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells. Biochim Biophys Acta 1973;323:466-483.
    • (1973) Biochim Biophys Acta , vol.323 , pp. 466-483
    • Dano, K.1
  • 12
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976;455:152-162.
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 13
    • 0023153149 scopus 로고
    • The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation
    • Ueda K, Clark DP, Chen CJ et al. The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation. J Biol Chem 1987;262:505-508.
    • (1987) J Biol Chem , vol.262 , pp. 505-508
    • Ueda, K.1    Clark, D.P.2    Chen, C.J.3
  • 14
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 2001;11:1156-1166.
    • (2001) Genome Res , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 15
    • 0035682157 scopus 로고    scopus 로고
    • The mechanism of action of multidrug-resistance-linked P-glycoprotein
    • Sauna ZE, Smith MM, Muller M et al. The mechanism of action of multidrug-resistance-linked P-glycoprotein. J Bioenerg Biomembr 2001;33:481-491.
    • (2001) J Bioenerg Biomembr , vol.33 , pp. 481-491
    • Sauna, Z.E.1    Smith, M.M.2    Muller, M.3
  • 16
    • 0036224915 scopus 로고    scopus 로고
    • Inhibitors of multidrug resistance to antitumor agents (MDR)
    • Avendano C, Menendez JC. Inhibitors of multidrug resistance to antitumor agents (MDR). Curr Med Chem 2002;9:159-193.
    • (2002) Curr Med Chem , vol.9 , pp. 159-193
    • Avendano, C.1    Menendez, J.C.2
  • 17
    • 0027095653 scopus 로고
    • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • Cole SP, Bhardwaj G, Gerlach JH et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 1992;258:1650-1654.
    • (1992) Science , vol.258 , pp. 1650-1654
    • Cole, S.P.1    Bhardwaj, G.2    Gerlach, J.H.3
  • 18
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst P, Evers R, Kool M et al. A family of drug transporters: the multidrug resistance-associated proteins. J Natl Cancer Inst 2000;92:1295-1302.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3
  • 19
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
    • Loe DW, Deeley RG, Cole SP. Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. Cancer Res 1998;58:5130-5136.
    • (1998) Cancer Res , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 20
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1) in human cancer cell lines
    • Kool M, de Haas M, Scheffer GL et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1) in human cancer cell lines. Cancer Res 1997;57:3537-3547.
    • (1997) Cancer Res , vol.57 , pp. 3537-3547
    • Kool, M.1    De Haas, M.2    Scheffer, G.L.3
  • 21
    • 0033407050 scopus 로고    scopus 로고
    • Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents
    • Zeng H, Bain LJ, Belinsky MG et al. Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents. Cancer Res 1999;59:5964-5967.
    • (1999) Cancer Res , vol.59 , pp. 5964-5967
    • Zeng, H.1    Bain, L.J.2    Belinsky, M.G.3
  • 22
    • 0032879904 scopus 로고    scopus 로고
    • MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    • Schuetz JD, Connelly MC, Sun D et al. MRP4: a previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat Med 1999;5:1048-1051.
    • (1999) Nat Med , vol.5 , pp. 1048-1051
    • Schuetz, J.D.1    Connelly, M.C.2    Sun, D.3
  • 23
    • 0035682486 scopus 로고    scopus 로고
    • MRP subfamily transporters and resistance to anticancer agents
    • Kruh GD, Zeng H, Rea PA et al. MRP subfamily transporters and resistance to anticancer agents. J Bioenerg Biomembr 2001;33:493-501.
    • (2001) J Bioenerg Biomembr , vol.33 , pp. 493-501
    • Kruh, G.D.1    Zeng, H.2    Rea, P.A.3
  • 24
    • 0036829109 scopus 로고    scopus 로고
    • Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6)
    • Belinsky MG, Chen ZS, Shchaveleva I et al. Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). Cancer Res 2002;62:6172-6177.
    • (2002) Cancer Res , vol.62 , pp. 6172-6177
    • Belinsky, M.G.1    Chen, Z.S.2    Shchaveleva, I.3
  • 25
    • 0033429542 scopus 로고    scopus 로고
    • Camptothecin resistance: Role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
    • Brangi M, Litman T, Ciotti M et al. Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. Cancer Res 1999;59:5938-5946.
    • (1999) Cancer Res , vol.59 , pp. 5938-5946
    • Brangi, M.1    Litman, T.2    Ciotti, M.3
  • 26
    • 0029022589 scopus 로고
    • Idenfificafion of a sister gene to P-glycoprotein
    • Childs S, Yeh RL, Georges E et al. Idenfificafion of a sister gene to P-glycoprotein. Cancer Res 1995;55:2029-2034.
    • (1995) Cancer Res , vol.55 , pp. 2029-2034
    • Childs, S.1    Yeh, R.L.2    Georges, E.3
  • 27
    • 0035870262 scopus 로고    scopus 로고
    • Cloning and characterization of human adenosine 5′ -triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2)
    • Vulevic B, Chen Z, Boyd JT et al. Cloning and characterization of human adenosine 5′-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). Cancer Res 2001;61:3339-3347.
    • (2001) Cancer Res , vol.61 , pp. 3339-3347
    • Vulevic, B.1    Chen, Z.2    Boyd, J.T.3
  • 28
    • 13344278004 scopus 로고    scopus 로고
    • Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia
    • List AF, Spier CS, Grogan TM et al. Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia. Blood 1996;87:2464-2469.
    • (1996) Blood , vol.87 , pp. 2464-2469
    • List, A.F.1    Spier, C.S.2    Grogan, T.M.3
  • 29
    • 0034473776 scopus 로고    scopus 로고
    • The role of HER-2 expression in predicting response to therapy in breast cancer
    • discussion 92-100
    • Mass R. The role of HER-2 expression in predicting response to therapy in breast cancer. Semin Oncol 2000;27(suppl 11):46-52; discussion 92-100.
    • (2000) Semin Oncol , vol.27 , Issue.SUPPL. 11 , pp. 46-52
    • Mass, R.1
  • 30
    • 0030991321 scopus 로고    scopus 로고
    • Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi
    • Chen CC, Meadows B, Regis J et al. Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi. Clin Cancer Res 1997;3:545-552.
    • (1997) Clin Cancer Res , vol.3 , pp. 545-552
    • Chen, C.C.1    Meadows, B.2    Regis, J.3
  • 31
    • 0042132423 scopus 로고
    • Expression of a multidrug-resistance gene in human tumors and tissues
    • Fojo AT, Ueda K, Slamon DJ et al. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 1987;84:265-269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 265-269
    • Fojo, A.T.1    Ueda, K.2    Slamon, D.J.3
  • 32
    • 17744395099 scopus 로고    scopus 로고
    • Expression of functional markers in acute nonlymphoblastic leukemia
    • Han K, Kahng J, Kim M et al. Expression of functional markers in acute nonlymphoblastic leukemia. Acta Haematol 2000;104:174-180.
    • (2000) Acta Haematol , vol.104 , pp. 174-180
    • Han, K.1    Kahng, J.2    Kim, M.3
  • 33
    • 0033179095 scopus 로고    scopus 로고
    • Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: A Southwest Oncology Group study
    • Leith CP, Kopecky KJ, Chen IM et al. Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group study. Blood 1999;94:1086-1099.
    • (1999) Blood , vol.94 , pp. 1086-1099
    • Leith, C.P.1    Kopecky, K.J.2    Chen, I.M.3
  • 34
    • 0034043234 scopus 로고    scopus 로고
    • P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy
    • Broxterman HJ, Sonneveld P, van Putten WJ et al. P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy. Leukemia 2000;14:1018-1024.
    • (2000) Leukemia , vol.14 , pp. 1018-1024
    • Broxterman, H.J.1    Sonneveld, P.2    Van Putten, W.J.3
  • 35
    • 0029928803 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein (MRP) in haematological malignancies
    • Nooter K, Burger H, Stoter G. Multidrug resistance-associated protein (MRP) in haematological malignancies. Leuk Lymphoma 1996;20:381-387.
    • (1996) Leuk Lymphoma , vol.20 , pp. 381-387
    • Nooter, K.1    Burger, H.2    Stoter, G.3
  • 36
    • 0036121001 scopus 로고    scopus 로고
    • Multidrug resistance mechanisms in chronic lymphocytic leukaemia
    • Consoli U, Santonocito A, Stagno F et al. Multidrug resistance mechanisms in chronic lymphocytic leukaemia. Br J Haematol 2002;116:774-780.
    • (2002) Br J Haematol , vol.116 , pp. 774-780
    • Consoli, U.1    Santonocito, A.2    Stagno, F.3
  • 37
    • 0032430818 scopus 로고    scopus 로고
    • Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival
    • Borg AG, Burgess R, Green LM et al. Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival. Br J Haematol 1998;103:1083-1091.
    • (1998) Br J Haematol , vol.103 , pp. 1083-1091
    • Borg, A.G.1    Burgess, R.2    Green, L.M.3
  • 38
    • 0030920342 scopus 로고    scopus 로고
    • Multidrug resistance in breast cancer: A meta-analysis MDR1/gp170 expression and its possible functional significance
    • Trock BJ, Leonessa F, Clarke R. Multidrug resistance in breast cancer: a meta-analysis MDR1/gp170 expression and its possible functional significance. J Natl Cancer Inst 1997;89:917-931.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 917-931
    • Trock, B.J.1    Leonessa, F.2    Clarke, R.3
  • 39
    • 0031018861 scopus 로고    scopus 로고
    • P-glycoprotein: The intermediate end point of drug response to induction chemotherapy in locally advanced breast cancer
    • Chung HC, Rha SY, Kim JH et al. P-glycoprotein: the intermediate end point of drug response to induction chemotherapy in locally advanced breast cancer. Breast Cancer Res Treat 1997;42:65-72.
    • (1997) Breast Cancer Res Treat , vol.42 , pp. 65-72
    • Chung, H.C.1    Rha, S.Y.2    Kim, J.H.3
  • 40
    • 0030045286 scopus 로고    scopus 로고
    • Sequential assessment of multidrug resistance phenotype and measurement of S-phase fraction as predictive markers of breast cancer response to neoadjuvant chemotherapy
    • Chevillard S, Pouillart P, Beldjord C et al. Sequential assessment of multidrug resistance phenotype and measurement of S-phase fraction as predictive markers of breast cancer response to neoadjuvant chemotherapy. Cancer 1996;77:292-300.
    • (1996) Cancer , vol.77 , pp. 292-300
    • Chevillard, S.1    Pouillart, P.2    Beldjord, C.3
  • 41
    • 0033038623 scopus 로고    scopus 로고
    • Expression of multidrug resistance protein-related genes in lung cancer: Correlation with drug response
    • Young LC, Campling BG, Voskoglou-Nomikos T et al. Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response. Clin Cancer Res 1999;5:673-680.
    • (1999) Clin Cancer Res , vol.5 , pp. 673-680
    • Young, L.C.1    Campling, B.G.2    Voskoglou-Nomikos, T.3
  • 42
    • 0003360972 scopus 로고    scopus 로고
    • A phase 3 study of PSC 833 in combination with paclitaxel and carboplatin (PC-PSC) versus paclitaxel and carboplatin (PC) alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary cancer of the peritoneum
    • Joly F, Mangioni C, Nicoletto M et al. A phase 3 study of PSC 833 in combination with paclitaxel and carboplatin (PC-PSC) versus paclitaxel and carboplatin (PC) alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary cancer of the peritoneum. Proc Am Soc Clin Oncol 2002;21:202a.
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Joly, F.1    Mangioni, C.2    Nicoletto, M.3
  • 43
    • 0029939666 scopus 로고    scopus 로고
    • Diagnosis and reversal of multidrug resistance in paediatric cancers
    • Chan HSL, Grogan TM, DeBoer G et al. Diagnosis and reversal of multidrug resistance in paediatric cancers. Eur J Cancer 1996;32A:1051-1061.
    • (1996) Eur J Cancer , vol.32 A , pp. 1051-1061
    • Chan, H.S.L.1    Grogan, T.M.2    DeBoer, G.3
  • 44
    • 0029983195 scopus 로고    scopus 로고
    • High level expression of the multidrug resistance (MDR1) gene in the normal bladder urothelium: A potential involvement in protection against carcinogens?
    • Clifford SC, Neal DE, Lunec J. High level expression of the multidrug resistance (MDR1) gene in the normal bladder urothelium: a potential involvement in protection against carcinogens? Carcinogenesis 1996;17:601-604.
    • (1996) Carcinogenesis , vol.17 , pp. 601-604
    • Clifford, S.C.1    Neal, D.E.2    Lunec, J.3
  • 45
    • 0030029210 scopus 로고    scopus 로고
    • Alterations in expression of the multidrug resistance-associated protein (MRP) gene in high-grade transitional cell carcinoma of the bladder
    • Clifford SC, Neal DE, Lunec J. Alterations in expression of the multidrug resistance-associated protein (MRP) gene in high-grade transitional cell carcinoma of the bladder. Br J Cancer 1996;73:659-666.
    • (1996) Br J Cancer , vol.73 , pp. 659-666
    • Clifford, S.C.1    Neal, D.E.2    Lunec, J.3
  • 46
    • 0036533566 scopus 로고    scopus 로고
    • Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin
    • Tada Y, Wada M, Migita T et al. Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin. Int J Cancer 2002;98:630-635.
    • (2002) Int J Cancer , vol.98 , pp. 630-635
    • Tada, Y.1    Wada, M.2    Migita, T.3
  • 47
    • 0028175407 scopus 로고
    • P-glycoprotein expression in bladder cancer
    • Park J, Shinohara N, Liebert M et al. P-glycoprotein expression in bladder cancer. J Urol 1994;151:43-46.
    • (1994) J Urol , vol.151 , pp. 43-46
    • Park, J.1    Shinohara, N.2    Liebert, M.3
  • 48
    • 0030979119 scopus 로고    scopus 로고
    • Clinical significance of multi-drug resistance associated protein and P-glycoprotein in patients with bladder cancer
    • discussion 1264-1265
    • Nakagawa M, Emoto A, Nasu N et al. Clinical significance of multi-drug resistance associated protein and P-glycoprotein in patients with bladder cancer. J Urol 1997;157:1260-1264; discussion 1264-1265.
    • (1997) J Urol , vol.157 , pp. 1260-1264
    • Nakagawa, M.1    Emoto, A.2    Nasu, N.3
  • 49
    • 0029770135 scopus 로고    scopus 로고
    • MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors
    • Toth K, Vaughan MM, Peress NS et al. MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors. Am J Pathol 1996;149:853-858.
    • (1996) Am J Pathol , vol.149 , pp. 853-858
    • Toth, K.1    Vaughan, M.M.2    Peress, N.S.3
  • 50
    • 0036772386 scopus 로고    scopus 로고
    • Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tamours detected by the BXP-21 monoclonal antibody in paraffin-embedded material
    • Diestra JE, Scheffer GL, Catala I et al. Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tamours detected by the BXP-21 monoclonal antibody in paraffin-embedded material. J Pathol 2002;198:213-219.
    • (2002) J Pathol , vol.198 , pp. 213-219
    • Diestra, J.E.1    Scheffer, G.L.2    Catala, I.3
  • 51
    • 0024292717 scopus 로고
    • An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene
    • Choi KH, Chen CJ, Kriegler M et al. An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell 1988;53:519-529.
    • (1988) Cell , vol.53 , pp. 519-529
    • Choi, K.H.1    Chen, C.J.2    Kriegler, M.3
  • 52
    • 0028229150 scopus 로고
    • Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
    • Schinkel AH, Smit JJ, van Tellingen O et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 1994;77:491-502.
    • (1994) Cell , vol.77 , pp. 491-502
    • Schinkel, A.H.1    Smit, J.J.2    Van Tellingen, O.3
  • 53
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhancing cytotoxicity of vincristine and vinblastine by verapamil
    • Tsuruo T, Iida H, Tsukagoshi S et al. Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhancing cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res 1981;41:1967-1972.
    • (1981) Cancer Res , vol.41 , pp. 1967-1972
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3
  • 54
    • 0026634681 scopus 로고
    • Modulation of multidrug-resistant multiple myeloma by cyclosporin
    • The Leukaemia Group of the EORTC and the HOVON
    • Sonneveld P, Durie BG, Lokhorst HM et al. Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON. Lancet 1992;340:255-259.
    • (1992) Lancet , vol.340 , pp. 255-259
    • Sonneveld, P.1    Durie, B.G.2    Lokhorst, H.M.3
  • 55
    • 0028094485 scopus 로고
    • Clinical modulation of multidrug resistance in multiple myeloma: Effect of cyclosporine on resistant tumor cells
    • Sonneveld P, Schoester M, de Leeuw K. Clinical modulation of multidrug resistance in multiple myeloma: effect of cyclosporine on resistant tumor cells. J Clin Oncol 1994;12:1584-1591.
    • (1994) J Clin Oncol , vol.12 , pp. 1584-1591
    • Sonneveld, P.1    Schoester, M.2    De Leeuw, K.3
  • 56
    • 0035673972 scopus 로고    scopus 로고
    • Cyclosporin A combined with vincristine, doxorubicin and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: An EORTC-HOVON randomized phase III study (06914)
    • Sonneveld P, Suciu S, Weijermans P et al. Cyclosporin A combined with vincristine, doxorubicin and dexamethasone (VAD) compared with VAD alone in patients with advanced refractory multiple myeloma: an EORTC-HOVON randomized phase III study (06914). Br J Haematol 2001;115:895-902.
    • (2001) Br J Haematol , vol.115 , pp. 895-902
    • Sonneveld, P.1    Suciu, S.2    Weijermans, P.3
  • 57
    • 0028816350 scopus 로고
    • A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma
    • A Southwest Oncology Group Study
    • Dalton WS, Crowley JJ, Salmon SS et al. A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group Study. Cancer 1995;75:815-820.
    • (1995) Cancer , vol.75 , pp. 815-820
    • Dalton, W.S.1    Crowley, J.J.2    Salmon, S.S.3
  • 58
    • 0026584396 scopus 로고
    • Cyclosporins as drug resistance modifiers
    • Twentyman PR. Cyclosporins as drug resistance modifiers. Biochem Pharmacol 1992;43:109-117.
    • (1992) Biochem Pharmacol , vol.43 , pp. 109-117
    • Twentyman, P.R.1
  • 59
    • 85163513522 scopus 로고    scopus 로고
    • Solving the problems of multidrug resistance: ABC transporters in clinical oncology
    • Holland IB, Cole SP, Kuchler K et al., eds. ABC Proteins: From Bacteria to Man. London: Elsevier Science
    • Bates SE. Solving the problems of multidrug resistance: ABC transporters in clinical oncology. In: Holland IB, Cole SP, Kuchler K et al., eds. ABC Proteins: From Bacteria to Man. London: Elsevier Science, 2002:359-391.
    • (2002) ABC Proteins: From Bacteria to Man , pp. 359-391
    • Bates, S.E.1
  • 60
    • 0036300981 scopus 로고    scopus 로고
    • Safety and efficacy of the multidrug resistance inhibitor Incel (biricodar; VX-710) in combination with paclitaxel for advanced breast cancer refractory to paclitaxel
    • Toppmeyer D, Seidman AD, Pollak M et al. Safety and efficacy of the multidrug resistance inhibitor Incel (biricodar; VX-710) in combination with paclitaxel for advanced breast cancer refractory to paclitaxel. Clin Cancer Res 2002;8:670-678.
    • (2002) Clin Cancer Res , vol.8 , pp. 670-678
    • Toppmeyer, D.1    Seidman, A.D.2    Pollak, M.3
  • 61
    • 0036190730 scopus 로고    scopus 로고
    • Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma
    • Bramwell VH, Morris D, Ernst DS et al. Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma. Clin Cancer Res 2002;8:383-393.
    • (2002) Clin Cancer Res , vol.8 , pp. 383-393
    • Bramwell, V.H.1    Morris, D.2    Ernst, D.S.3
  • 62
  • 63
    • 0033993578 scopus 로고    scopus 로고
    • Phase I study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies
    • Fracasso PM, Westervelt P, Fears CL et al. Phase I study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies. J Clin Oncol 2000;18:1124-1134.
    • (2000) J Clin Oncol , vol.18 , pp. 1124-1134
    • Fracasso, P.M.1    Westervelt, P.2    Fears, C.L.3
  • 65
    • 0032960840 scopus 로고    scopus 로고
    • + cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833
    • + cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833. Blood 1999;93:306-314.
    • (1999) Blood , vol.93 , pp. 306-314
    • Robey, R.1    Bakke, S.2    Stein, W.3
  • 66
    • 0035876039 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin
    • Peck RA, Hewett J, Harding MW et al. Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin. J Clin Oncol 2001;19:3130-3141.
    • (2001) J Clin Oncol , vol.19 , pp. 3130-3141
    • Peck, R.A.1    Hewett, J.2    Harding, M.W.3
  • 67
    • 0037316891 scopus 로고    scopus 로고
    • 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576
    • 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576. Clin Cancer Res 2003;9:650-656.
    • (2003) Clin Cancer Res , vol.9 , pp. 650-656
    • Agrawal, M.1    Abraham, J.2    Balis, F.M.3
  • 68
    • 0031804471 scopus 로고    scopus 로고
    • Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer
    • Ciarmiello A, Del Vecchio S, Silvestro P et al. Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer. J Clin Oncol 1998;16:1677-1683.
    • (1998) J Clin Oncol , vol.16 , pp. 1677-1683
    • Ciarmiello, A.1    Del Vecchio, S.2    Silvestro, P.3
  • 69
    • 0035760302 scopus 로고    scopus 로고
    • Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: A Southwest Oncology Group study
    • List AF, Kopecky KJ, Willman CL et al. Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study. Blood 2001;98:3212-3220.
    • (2001) Blood , vol.98 , pp. 3212-3220
    • List, A.F.1    Kopecky, K.J.2    Willman, C.L.3
  • 70
    • 9444257012 scopus 로고    scopus 로고
    • Combination of quinine as a potential reversing agent with mitoxantrone and cytarabine for the treatment of acute leukemias: A randomized multicenter study
    • Solary E, Witz B, Caillot D et al. Combination of quinine as a potential reversing agent with mitoxantrone and cytarabine for the treatment of acute leukemias: a randomized multicenter study. Blood 1996;88:1198-1205.
    • (1996) Blood , vol.88 , pp. 1198-1205
    • Solary, E.1    Witz, B.2    Caillot, D.3
  • 71
    • 0037103189 scopus 로고    scopus 로고
    • Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720
    • Baer MR, George SL, Dodge RK et al. Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720. Blood 2002;100:1224-1232.
    • (2002) Blood , vol.100 , pp. 1224-1232
    • Baer, M.R.1    George, S.L.2    Dodge, R.K.3
  • 72
    • 0033635917 scopus 로고    scopus 로고
    • Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma
    • Belpomme D, Gauthier S, Pujade-Lauraine E et al. Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma. Ann Oncol 2000;11:1471-1476.
    • (2000) Ann Oncol , vol.11 , pp. 1471-1476
    • Belpomme, D.1    Gauthier, S.2    Pujade-Lauraine, E.3
  • 73
    • 0027256051 scopus 로고
    • Oral verapamil with chemotherapy for advanced non-small cell lung cancer: A randomised study
    • Millward MJ, Cantwell BM, Munro NC et al. Oral verapamil with chemotherapy for advanced non-small cell lung cancer: a randomised study. Br J Cancer 1993;67:1031-1035.
    • (1993) Br J Cancer , vol.67 , pp. 1031-1035
    • Millward, M.J.1    Cantwell, B.M.2    Munro, N.C.3
  • 74
    • 0035876393 scopus 로고    scopus 로고
    • Phase II study of paclitaxel and valspodar (PSC 833) in refractory ovarian carcinoma: A gynecologic oncology group study
    • Fracasso PM, Brady MF, Moore DH et al. Phase II study of paclitaxel and valspodar (PSC 833) in refractory ovarian carcinoma: a gynecologic oncology group study. J Clin Oncol 2001;19:2975-2982.
    • (2001) J Clin Oncol , vol.19 , pp. 2975-2982
    • Fracasso, P.M.1    Brady, M.F.2    Moore, D.H.3
  • 75
    • 0031686969 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP
    • Rowinsky EK, Smith L, Wang YM et al. Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP. J Clin Oncol 1998;16:2964-2976.
    • (1998) J Clin Oncol , vol.16 , pp. 2964-2976
    • Rowinsky, E.K.1    Smith, L.2    Wang, Y.M.3
  • 76
    • 0036445653 scopus 로고    scopus 로고
    • A phase II study of the MDR inhibitor biricodar (INCEL, VX-710) and paclitaxel in women with advanced ovarian cancer refractory to paclitaxel therapy
    • Seiden MV, Swenerton KD, Matulonis U et al. A phase II study of the MDR inhibitor biricodar (INCEL, VX-710) and paclitaxel in women with advanced ovarian cancer refractory to paclitaxel therapy. Gynecol Oncol 2002;86;302-310.
    • (2002) Gynecol Oncol , vol.86 , pp. 302-310
    • Seiden, M.V.1    Swenerton, K.D.2    Matulonis, U.3
  • 77
    • 0028841512 scopus 로고
    • Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833
    • Beketic-Oreskovic L, Duran GE, Chen G et al. Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833. J Natl Cancer Inst 1995;87:1593-1602.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1593-1602
    • Beketic-Oreskovic, L.1    Duran, G.E.2    Chen, G.3
  • 78
    • 0034792174 scopus 로고    scopus 로고
    • In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line
    • Cocker HA, Tiffin N, Pritchard-Jones K et al. In vitro prevention of the emergence of multidrug resistance in a pediatric rhabdomyosarcoma cell line. Clin Cancer Res 2001;7:3193-3198.
    • (2001) Clin Cancer Res , vol.7 , pp. 3193-3198
    • Cocker, H.A.1    Tiffin, N.2    Pritchard-Jones, K.3
  • 79
    • 0027274736 scopus 로고
    • Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia
    • List AF, Spier C, Greer J et al. Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia. J Clin Oncol 1993;11:1652-1660.
    • (1993) J Clin Oncol , vol.11 , pp. 1652-1660
    • List, A.F.1    Spier, C.2    Greer, J.3
  • 80
    • 0033063333 scopus 로고    scopus 로고
    • Kinetic concepts in the systemic drug therapy of breast cancer
    • Norton L. Kinetic concepts in the systemic drug therapy of breast cancer. Semin Oncol 1999;26(suppl 2):11-20.
    • (1999) Semin Oncol , vol.26 , Issue.SUPPL. 2 , pp. 11-20
    • Norton, L.1
  • 81
    • 0001583660 scopus 로고    scopus 로고
    • Coadministration of oral cyclosporin A enables oral therapy with paclitaxel
    • Meerum Terwogt JM, Malingre MM, Beijnen JH et al. Coadministration of oral cyclosporin A enables oral therapy with paclitaxel. Clin Cancer Res 1999;5:3379-3384.
    • (1999) Clin Cancer Res , vol.5 , pp. 3379-3384
    • Meerum Terwogt, J.M.1    Malingre, M.M.2    Beijnen, J.H.3
  • 82
    • 0036895360 scopus 로고    scopus 로고
    • Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer
    • Kruijtzer CM, Schellens JHM, Mezger J et al. Phase II and pharmacologic study of weekly oral paclitaxel plus cyclosporine in patients with advanced non-small-cell lung cancer. J Clin Oncol 2002;20:4508-4516.
    • (2002) J Clin Oncol , vol.20 , pp. 4508-4516
    • Kruijtzer, C.M.1    Schellens, J.H.M.2    Mezger, J.3
  • 83
    • 0037294483 scopus 로고    scopus 로고
    • Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer
    • Kruijtzer CM, Boot H, Beijnen JH et al. Weekly oral paclitaxel as first-line treatment in patients with advanced gastric cancer. Ann Oncol 2003;14:197-204.
    • (2003) Ann Oncol , vol.14 , pp. 197-204
    • Kruijtzer, C.M.1    Boot, H.2    Beijnen, J.H.3
  • 84
    • 0028801904 scopus 로고
    • Inhibition of intestinal P-glycoprotein and effects on etoposide absorption
    • Leu BL, Huang JD. Inhibition of intestinal P-glycoprotein and effects on etoposide absorption. Cancer Chemother Pharmacol 1995;35:432-436.
    • (1995) Cancer Chemother Pharmacol , vol.35 , pp. 432-436
    • Leu, B.L.1    Huang, J.D.2
  • 85
    • 0035749772 scopus 로고    scopus 로고
    • Polymorphisms in the ABC drug transporter gene MDR1
    • Brinkmann U, Eichelbaum M. Polymorphisms in the ABC drug transporter gene MDR1. Pharmacogenomics J 2001;1:59-64.
    • (2001) Pharmacogenomics J , vol.1 , pp. 59-64
    • Brinkmann, U.1    Eichelbaum, M.2
  • 86
    • 0036896380 scopus 로고    scopus 로고
    • Region-dependent modulation of intestinal permeability by drug efflux transporters: In vitro studies in mdr1a(-/-) mouse intestine
    • Stephens RH, Tanianis-Hughes J, Higgs NB et al. Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a(-/-) mouse intestine. J Pharmacol Exp Ther 2002;303:1095-1101.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 1095-1101
    • Stephens, R.H.1    Tanianis-Hughes, J.2    Higgs, N.B.3
  • 87
    • 0035870289 scopus 로고    scopus 로고
    • Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
    • Maliepaard M, Scheffer GL, Faneyte IF et al. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res 2001;61:3458-3464.
    • (2001) Cancer Res , vol.61 , pp. 3458-3464
    • Maliepaard, M.1    Scheffer, G.L.2    Faneyte, I.F.3
  • 88
    • 0036644903 scopus 로고    scopus 로고
    • Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918
    • Kruijtzer CM, Beijnen JH, Rosing H et al. Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918. J Clin Oncol 2002;20:2943-2950.
    • (2002) J Clin Oncol , vol.20 , pp. 2943-2950
    • Kruijtzer, C.M.1    Beijnen, J.H.2    Rosing, H.3
  • 89
    • 18844482235 scopus 로고    scopus 로고
    • A phase 1 study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide, and the MDR modulator PSC 833: A Southwest Oncology Group study 9617
    • Chauncey TR, Rankin C, Anderson JE et al. A phase 1 study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide, and the MDR modulator PSC 833: a Southwest Oncology Group study 9617. Leuk Res 2000;24:567-574.
    • (2000) Leuk Res , vol.24 , pp. 567-574
    • Chauncey, T.R.1    Rankin, C.2    Anderson, J.E.3
  • 90
    • 0028793942 scopus 로고
    • Expression of multidrug resistance-associated protein (MRP) and multidrug resistance (MDR1) genes in acute myeloid leukemia
    • Zhou DC, Zittoun R, Marie JP. Expression of multidrug resistance-associated protein (MRP) and multidrug resistance (MDR1) genes in acute myeloid leukemia. Leukemia 1995;9:1661-1666.
    • (1995) Leukemia , vol.9 , pp. 1661-1666
    • Zhou, D.C.1    Zittoun, R.2    Marie, J.P.3
  • 91
    • 0033179207 scopus 로고    scopus 로고
    • Simultaneous activity of MRP1 and P-gp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia
    • Legrand O, Simonin G, Beauchamp-Nicoud A et al. Simultaneous activity of MRP1 and P-gp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia. Blood 1999;94:1046-1056.
    • (1999) Blood , vol.94 , pp. 1046-1056
    • Legrand, O.1    Simonin, G.2    Beauchamp-Nicoud, A.3
  • 92
    • 0027507266 scopus 로고
    • P-glycoprotein expression in human plasma cell myeloma: Correlation with prior chemotherapy
    • Grogan TM, Spier CM, Salmon SE et al. P-glycoprotein expression in human plasma cell myeloma: correlation with prior chemotherapy. Blood 1993;81:490-495.
    • (1993) Blood , vol.81 , pp. 490-495
    • Grogan, T.M.1    Spier, C.M.2    Salmon, S.E.3
  • 93
    • 0028025021 scopus 로고
    • Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoeitic cells
    • Abbaszadegan MR, Futscher BW, Klimecki WT et al. Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoeitic cells. Cancer Res 1994;54:4676-4679.
    • (1994) Cancer Res , vol.54 , pp. 4676-4679
    • Abbaszadegan, M.R.1    Futscher, B.W.2    Klimecki, W.T.3
  • 94
    • 0029977802 scopus 로고    scopus 로고
    • MRP and MDR1 gene expression in primary breast carcinomas
    • Filipits M, Suchomel RW, Dekan G et al. MRP and MDR1 gene expression in primary breast carcinomas. Clin Cancer Res 1996;2:1231-1237.
    • (1996) Clin Cancer Res , vol.2 , pp. 1231-1237
    • Filipits, M.1    Suchomel, R.W.2    Dekan, G.3
  • 95
    • 0031936939 scopus 로고    scopus 로고
    • Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin
    • Mechetner E, Kyshtoobayeva A, Zonis S et al. Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin. Clin Cancer Res 1998;4:389-398.
    • (1998) Clin Cancer Res , vol.4 , pp. 389-398
    • Mechetner, E.1    Kyshtoobayeva, A.2    Zonis, S.3
  • 96
    • 0031866752 scopus 로고    scopus 로고
    • Multidrug resistance related genes and p53 expression in human non small cell lung cancer
    • Galimberti S, Marchetti A, Buttitta F et al: Multidrug resistance related genes and p53 expression in human non small cell lung cancer. Anticancer Res 1998;18:2973-2976.
    • (1998) Anticancer Res , vol.18 , pp. 2973-2976
    • Galimberti, S.1    Marchetti, A.2    Buttitta, F.3
  • 97
    • 0028830165 scopus 로고
    • Value of P-glycoprotein, glutathione S-transferase pi, c-erbB-2, and p53 as prognostic factors in ovarian carcinomas
    • van der Zee AG, Hollema H, Suurmeijer AJ et al. Value of P-glycoprotein, glutathione S-transferase pi, c-erbB-2, and p53 as prognostic factors in ovarian carcinomas. J Clin Oncol 1995;13:70-78.
    • (1995) J Clin Oncol , vol.13 , pp. 70-78
    • Van der Zee, A.G.1    Hollema, H.2    Suurmeijer, A.J.3
  • 98
    • 0032756995 scopus 로고    scopus 로고
    • Immunohistochemical evidence that P-glycoprotein in non-small cell lung cancers is associated with shorter survival
    • Yokoyama H, Ishida T, Sugio K et al. Immunohistochemical evidence that P-glycoprotein in non-small cell lung cancers is associated with shorter survival. Surg Today 1999;29:1141-1147.
    • (1999) Surg Today , vol.29 , pp. 1141-1147
    • Yokoyama, H.1    Ishida, T.2    Sugio, K.3
  • 99
    • 0030905994 scopus 로고    scopus 로고
    • Expression of multidrug resistance-associated protein gene in Ewing's sarcoma and malignant peripheral neuroectodermal tumor of bone
    • Oda Y, Dockhorn-Dworniczak B, Jurgens H et al. Expression of multidrug resistance-associated protein gene in Ewing's sarcoma and malignant peripheral neuroectodermal tumor of bone. J Cancer Res Clin Oncol 1997;123:237-239.
    • (1997) J Cancer Res Clin Oncol , vol.123 , pp. 237-239
    • Oda, Y.1    Dockhorn-Dworniczak, B.2    Jurgens, H.3
  • 100
    • 17844380242 scopus 로고    scopus 로고
    • Effect of P-glycoprotein expression on outcome in the Ewing family of tumors
    • Perri T, Fogel M, Mor S et al. Effect of P-glycoprotein expression on outcome in the Ewing family of tumors. Pediatr Hematol Oncol 2001;18:325-334.
    • (2001) Pediatr Hematol Oncol , vol.18 , pp. 325-334
    • Perri, T.1    Fogel, M.2    Mor, S.3
  • 101
    • 0031792926 scopus 로고    scopus 로고
    • Expression of multidrug resistance protein gene in patients with glioma after chemotherapy
    • Abe T, Mori T, Wakabayashi Y et al. Expression of multidrug resistance protein gene in patients with glioma after chemotherapy. J Neurooncol 1998;40:11-18.
    • (1998) J Neurooncol , vol.40 , pp. 11-18
    • Abe, T.1    Mori, T.2    Wakabayashi, Y.3
  • 102
    • 0034478036 scopus 로고    scopus 로고
    • Drug resistance-associated factors in primary and secondary glioblastomas and their precursor tumors
    • Tews DS, Nissen A, Kulgen C et al. Drug resistance-associated factors in primary and secondary glioblastomas and their precursor tumors. J Neurooncol 2000;50:227-237.
    • (2000) J Neurooncol , vol.50 , pp. 227-237
    • Tews, D.S.1    Nissen, A.2    Kulgen, C.3
  • 103
    • 0024989789 scopus 로고
    • Expression of multidrug-resistance (MDR1) gene in normal epithelia and in invasive carcinomas of the uterine cervix
    • Riou GF, Zhou D, Ahomadegbe JC et al. Expression of multidrug-resistance (MDR1) gene in normal epithelia and in invasive carcinomas of the uterine cervix. J Natl Cancer Inst 1990;82:1493-1496.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1493-1496
    • Riou, G.F.1    Zhou, D.2    Ahomadegbe, J.C.3
  • 104
    • 0026521047 scopus 로고
    • Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue
    • Schneider J, Efferth T, Mattern J et al. Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue. Am J Obstet Gynecol 1992;166:825-829.
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 825-829
    • Schneider, J.1    Efferth, T.2    Mattern, J.3
  • 105
    • 0034234653 scopus 로고    scopus 로고
    • Expression of breast cancer resistance protein in blast cells from patients with acute leukemia
    • Ross DD, Karp JE, Chen TT et al. Expression of breast cancer resistance protein in blast cells from patients with acute leukemia. Blood 2000;96:365-368.
    • (2000) Blood , vol.96 , pp. 365-368
    • Ross, D.D.1    Karp, J.E.2    Chen, T.T.3
  • 106
    • 0037093101 scopus 로고    scopus 로고
    • Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia
    • van der Kolk DM, Vellenga E, Scheffer GL et al. Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia. Blood 2002;99:3763-3770.
    • (2002) Blood , vol.99 , pp. 3763-3770
    • Van der Kolk, D.M.1    Vellenga, E.2    Scheffer, G.L.3
  • 107
    • 0035726216 scopus 로고    scopus 로고
    • Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia
    • Sargent JM, Williamson CJ, Maliepaard M et al. Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia. Br J Haematol 2001;115:257-262.
    • (2001) Br J Haematol , vol.115 , pp. 257-262
    • Sargent, J.M.1    Williamson, C.J.2    Maliepaard, M.3
  • 108
    • 0036100195 scopus 로고    scopus 로고
    • Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)
    • van den Heuvel-Eibrink MM, Wiemer EA, Prins A et al. Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML). Leukemia 2002;16:833-839.
    • (2002) Leukemia , vol.16 , pp. 833-839
    • Van den Heuvel-Eibrink, M.M.1    Wiemer, E.A.2    Prins, A.3
  • 109
    • 0036052296 scopus 로고    scopus 로고
    • BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia
    • Steinbach D, Sell W, Voigt A et al. BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia. Leukemia 2002;16:1443-1447.
    • (2002) Leukemia , vol.16 , pp. 1443-1447
    • Steinbach, D.1    Sell, W.2    Voigt, A.3
  • 110
    • 0035012619 scopus 로고    scopus 로고
    • Expression of multidrug resistance-related transporters in human breast carcinoma
    • Kanzaki A, Toi M, Nakayama K et al. Expression of multidrug resistance-related transporters in human breast carcinoma. Jpn J Cancer Res 2001;92:452-458.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 452-458
    • Kanzaki, A.1    Toi, M.2    Nakayama, K.3
  • 111
    • 0036554732 scopus 로고    scopus 로고
    • Expression of the breast cancer resistance protein in breast cancer
    • Faneyte IF, Kristel PM, Maliepaard M et al. Expression of the breast cancer resistance protein in breast cancer. Clin Cancer Res 2002;8:1068-1074.
    • (2002) Clin Cancer Res , vol.8 , pp. 1068-1074
    • Faneyte, I.F.1    Kristel, P.M.2    Maliepaard, M.3
  • 112
    • 0036260972 scopus 로고    scopus 로고
    • Multidrug resistance related molecules in human and murine lung
    • Scheffer GL, Pijnenborg AC, Smit EF et al. Multidrug resistance related molecules in human and murine lung. J Clin Pathol 2002;55:332-339.
    • (2002) J Clin Pathol , vol.55 , pp. 332-339
    • Scheffer, G.L.1    Pijnenborg, A.C.2    Smit, E.F.3
  • 113
    • 0028020860 scopus 로고
    • Quinidine as a resistance modulator of epirubicin in advanced breast cancer: Mature results of a placebo-controlled randomized trial
    • Wishart GC, Bissett D, Paul J et al. Quinidine as a resistance modulator of epirubicin in advanced breast cancer: mature results of a placebo-controlled randomized trial. J Clin Oncol 1994;12:1771-1777.
    • (1994) J Clin Oncol , vol.12 , pp. 1771-1777
    • Wishart, G.C.1    Bissett, D.2    Paul, J.3
  • 114
    • 0027375301 scopus 로고
    • A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer
    • West of Scotland Lung Cancer Research Group and the Aberdeen Oncology Group
    • Milroy R. A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer. West of Scotland Lung Cancer Research Group and the Aberdeen Oncology Group. Br J Cancer 1993;68:813-818.
    • (1993) Br J Cancer , vol.68 , pp. 813-818
    • Milroy, R.1


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