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Volumn 16, Issue 4, 2015, Pages 427-446

The biology of IQGAP proteins: Beyond the cytoskeleton

Author keywords

biology; IQGAP1; IQGAP2; IQGAP3; therapeutics

Indexed keywords

ACTIN; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; APC PROTEIN; BACTERIAL ENZYME; BACTERIAL PROTEIN; CORTACTIN; DABRAFENIB; EZRIN; GLUCOSE; INSULIN; IQGAP PROTEIN; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; ONCOPROTEIN; RAS PROTEIN; SCAFFOLD PROTEIN; SORAFENIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VEMURAFENIB; VIMENTIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; IQGAP2 PROTEIN, HUMAN; IQGAP3 PROTEIN, HUMAN;

EID: 84926252376     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201439834     Document Type: Article
Times cited : (177)

References (221)
  • 1
    • 84867988900 scopus 로고    scopus 로고
    • Contractile-ring assembly in fission yeast cytokinesis: Recent advances and new perspectives
    • Lee IJ, Coffman VC, Wu JQ, (2012) Contractile-ring assembly in fission yeast cytokinesis: recent advances and new perspectives. Cytoskeleton 69: 751-763
    • (2012) Cytoskeleton , vol.69 , pp. 751-763
    • Lee, I.J.1    Coffman, V.C.2    Wu, J.Q.3
  • 2
    • 84858329431 scopus 로고    scopus 로고
    • IQGAP Family members in yeast, Dictyostelium, and mammalian cells
    • Shannon KB, (2012) IQGAP Family members in yeast, Dictyostelium, and mammalian cells. Int J Cell Biol 2012: 894817
    • (2012) Int J Cell Biol , vol.2012 , pp. 894817
    • Shannon, K.B.1
  • 4
    • 33646726750 scopus 로고    scopus 로고
    • IQGAP1 in cellular signaling: Bridging the GAP
    • Brown MD, Sacks DB, (2006) IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol 16: 242-249
    • (2006) Trends Cell Biol , vol.16 , pp. 242-249
    • Brown, M.D.1    Sacks, D.B.2
  • 5
    • 84856219974 scopus 로고    scopus 로고
    • IQGAP1 and its binding proteins control diverse biological functions
    • White CD, Erdemir HH, Sacks DB, (2012) IQGAP1 and its binding proteins control diverse biological functions. Cell Signal 24: 826-834
    • (2012) Cell Signal , vol.24 , pp. 826-834
    • White, C.D.1    Erdemir, H.H.2    Sacks, D.B.3
  • 6
    • 77953395353 scopus 로고    scopus 로고
    • An emerging role for IQGAP1 in regulating protein traffic
    • Osman M, (2010) An emerging role for IQGAP1 in regulating protein traffic. Sci World J 10: 944-953
    • (2010) Sci World J , vol.10 , pp. 944-953
    • Osman, M.1
  • 7
    • 0043093686 scopus 로고    scopus 로고
    • IQGAP proteins are integral components of cytoskeletal regulation
    • Briggs MW, Sacks DB, (2003) IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep 4: 571-574
    • (2003) EMBO Rep , vol.4 , pp. 571-574
    • Briggs, M.W.1    Sacks, D.B.2
  • 8
    • 0038787005 scopus 로고    scopus 로고
    • IQGAPs: Integrators of the cytoskeleton, cell adhesion machinery, and signaling networks
    • Mateer SC, Wang N, Bloom GS, (2003) IQGAPs: integrators of the cytoskeleton, cell adhesion machinery, and signaling networks. Cell Motil Cytoskeleton 55: 147-155
    • (2003) Cell Motil Cytoskeleton , vol.55 , pp. 147-155
    • Mateer, S.C.1    Wang, N.2    Bloom, G.S.3
  • 10
  • 12
    • 2342424547 scopus 로고    scopus 로고
    • IQGAP1 binds ERK2 and modulates its activity
    • Roy M, Li Z, Sacks DB, (2004) IQGAP1 binds ERK2 and modulates its activity. J Biol Chem 279: 17329-17337
    • (2004) J Biol Chem , vol.279 , pp. 17329-17337
    • Roy, M.1    Li, Z.2    Sacks, D.B.3
  • 13
    • 24344491858 scopus 로고    scopus 로고
    • IQGAP1 is a scaffold for mitogen-activated protein kinase signaling
    • Roy M, Li Z, Sacks DB, (2005) IQGAP1 is a scaffold for mitogen-activated protein kinase signaling. Mol Cell Biol 25: 7940-7952
    • (2005) Mol Cell Biol , vol.25 , pp. 7940-7952
    • Roy, M.1    Li, Z.2    Sacks, D.B.3
  • 15
    • 84894053464 scopus 로고    scopus 로고
    • IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function
    • Matsunaga H, Kubota K, Inoue T, Isono F, Ando O, (2014) IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function. Biochem Biophys Res Commun 444: 360-364
    • (2014) Biochem Biophys Res Commun , vol.444 , pp. 360-364
    • Matsunaga, H.1    Kubota, K.2    Inoue, T.3    Isono, F.4    Ando, O.5
  • 18
    • 0029891491 scopus 로고    scopus 로고
    • IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs
    • Hart MJ, Callow MG, Souza B, Polakis P, (1996) IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. EMBO J 15: 2997-3005
    • (1996) EMBO J , vol.15 , pp. 2997-3005
    • Hart, M.J.1    Callow, M.G.2    Souza, B.3    Polakis, P.4
  • 23
    • 0037025333 scopus 로고    scopus 로고
    • IQGAP1 is a component of Cdc42 signaling to the cytoskeleton
    • Swart-Mataraza JM, Li Z, Sacks DB, (2002) IQGAP1 is a component of Cdc42 signaling to the cytoskeleton. J Biol Chem 277: 24753-24763
    • (2002) J Biol Chem , vol.277 , pp. 24753-24763
    • Swart-Mataraza, J.M.1    Li, Z.2    Sacks, D.B.3
  • 24
    • 0030859462 scopus 로고    scopus 로고
    • Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase
    • Erickson JW, Cerione RA, Hart MJ, (1997) Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase. J Biol Chem 272: 24443-24447
    • (1997) J Biol Chem , vol.272 , pp. 24443-24447
    • Erickson, J.W.1    Cerione, R.A.2    Hart, M.J.3
  • 27
    • 38549143782 scopus 로고    scopus 로고
    • Cytokinesis in development and disease: Variations on a common theme
    • Li R, (2007) Cytokinesis in development and disease: variations on a common theme. Cell Mol Life Sci 64: 3044-3058
    • (2007) Cell Mol Life Sci , vol.64 , pp. 3044-3058
    • Li, R.1
  • 28
    • 0031444358 scopus 로고    scopus 로고
    • An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast
    • Epp JA, Chant J, (1997) An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast. Curr Biol 7: 921-929
    • (1997) Curr Biol , vol.7 , pp. 921-929
    • Epp, J.A.1    Chant, J.2
  • 29
    • 0032572583 scopus 로고    scopus 로고
    • Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton
    • Osman MA, Cerione RA, (1998) Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton. J Cell Biol 142: 443-455
    • (1998) J Cell Biol , vol.142 , pp. 443-455
    • Osman, M.A.1    Cerione, R.A.2
  • 30
    • 0032918702 scopus 로고    scopus 로고
    • The multiple roles of Cyk1p in the assembly and function of the actomyosin ring in budding yeast
    • Shannon KB, Li R, (1999) The multiple roles of Cyk1p in the assembly and function of the actomyosin ring in budding yeast. Mol Biol Cell 10: 283-296
    • (1999) Mol Biol Cell , vol.10 , pp. 283-296
    • Shannon, K.B.1    Li, R.2
  • 31
    • 0030040263 scopus 로고    scopus 로고
    • Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring
    • Chang F, Woollard A, Nurse P, (1996) Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. J Cell Sci 109 (Pt 1): 131-142
    • (1996) J Cell Sci , vol.109 , pp. 131-142
    • Chang, F.1    Woollard, A.2    Nurse, P.3
  • 32
    • 0032554902 scopus 로고    scopus 로고
    • Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body
    • Eng K, Naqvi NI, Wong KC, Balasubramanian MK, (1998) Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body. Curr Biol 8: 611-621
    • (1998) Curr Biol , vol.8 , pp. 611-621
    • Eng, K.1    Naqvi, N.I.2    Wong, K.C.3    Balasubramanian, M.K.4
  • 33
    • 0242362741 scopus 로고    scopus 로고
    • Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis
    • Wu JQ, Kuhn JR, Kovar DR, Pollard TD, (2003) Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis. Dev Cell 5: 723-734
    • (2003) Dev Cell , vol.5 , pp. 723-734
    • Wu, J.Q.1    Kuhn, J.R.2    Kovar, D.R.3    Pollard, T.D.4
  • 34
    • 56549088009 scopus 로고    scopus 로고
    • The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans
    • Li CR, Wang YM, Wang Y, (2008) The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans. EMBO J 27: 2998-3010
    • (2008) EMBO J , vol.27 , pp. 2998-3010
    • Li, C.R.1    Wang, Y.M.2    Wang, Y.3
  • 35
    • 33748276641 scopus 로고    scopus 로고
    • Rho GTPase signaling in Dictyostelium discoideum: Insights from the genome
    • Vlahou G, Rivero F, (2006) Rho GTPase signaling in Dictyostelium discoideum: insights from the genome. Eur J Cell Biol 85: 947-959
    • (2006) Eur J Cell Biol , vol.85 , pp. 947-959
    • Vlahou, G.1    Rivero, F.2
  • 36
    • 0030926552 scopus 로고    scopus 로고
    • Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis
    • Adachi H, Takahashi Y, Hasebe T, Shirouzu M, Yokoyama S, Sutoh K, (1997) Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis. J Cell Biol 137: 891-898
    • (1997) J Cell Biol , vol.137 , pp. 891-898
    • Adachi, H.1    Takahashi, Y.2    Hasebe, T.3    Shirouzu, M.4    Yokoyama, S.5    Sutoh, K.6
  • 37
    • 0030574044 scopus 로고    scopus 로고
    • DGAP1, a homologue of rasGTPase activating proteins that controls growth, cytokinesis, and development in Dictyostelium discoideum
    • Faix J, Dittrich W, (1996) DGAP1, a homologue of rasGTPase activating proteins that controls growth, cytokinesis, and development in Dictyostelium discoideum. FEBS Lett 394: 251-257
    • (1996) FEBS Lett , vol.394 , pp. 251-257
    • Faix, J.1    Dittrich, W.2
  • 38
    • 0035898686 scopus 로고    scopus 로고
    • Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins
    • Faix J, Weber I, Mintert U, Kohler J, Lottspeich F, Marriott G, (2001) Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins. EMBO J 20: 3705-3715
    • (2001) EMBO J , vol.20 , pp. 3705-3715
    • Faix, J.1    Weber, I.2    Mintert, U.3    Kohler, J.4    Lottspeich, F.5    Marriott, G.6
  • 40
    • 3042718729 scopus 로고    scopus 로고
    • Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms
    • Skop AR, Liu H, Yates J 3rd, Meyer BJ, Heald R, (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science 305: 61-66
    • (2004) Science , vol.305 , pp. 61-66
    • Skop, A.R.1    Liu, H.2    Yates, J.3    Meyer, B.J.4    Heald, R.5
  • 41
    • 52049114347 scopus 로고    scopus 로고
    • Cdc42 protein acts upstream of IQGAP1 and regulates cytokinesis in mouse oocytes and embryos
    • Bielak-Zmijewska A, Kolano A, Szczepanska K, Maleszewski M, Borsuk E, (2008) Cdc42 protein acts upstream of IQGAP1 and regulates cytokinesis in mouse oocytes and embryos. Dev Biol 322: 21-32
    • (2008) Dev Biol , vol.322 , pp. 21-32
    • Bielak-Zmijewska, A.1    Kolano, A.2    Szczepanska, K.3    Maleszewski, M.4    Borsuk, E.5
  • 42
    • 78449299390 scopus 로고    scopus 로고
    • The myriad roles of anillin during cytokinesis
    • Piekny AJ, Maddox AS, (2010) The myriad roles of anillin during cytokinesis. Semin Cell Dev Biol 21: 881-891
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 881-891
    • Piekny, A.J.1    Maddox, A.S.2
  • 45
    • 84911162014 scopus 로고    scopus 로고
    • Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis
    • Adachi M, Kawasaki A, Nojima H, Nishida E, Tsukita S, (2014) Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis. Genes Cells 19: 803-820
    • (2014) Genes Cells , vol.19 , pp. 803-820
    • Adachi, M.1    Kawasaki, A.2    Nojima, H.3    Nishida, E.4    Tsukita, S.5
  • 46
    • 84884670045 scopus 로고    scopus 로고
    • The podocyte slit diaphragm - From a thin grey line to a complex signalling hub
    • Grahammer F, Schell C, Huber TB, (2013) The podocyte slit diaphragm-from a thin grey line to a complex signalling hub. Nat Rev Nephrol 9: 587-598
    • (2013) Nat Rev Nephrol , vol.9 , pp. 587-598
    • Grahammer, F.1    Schell, C.2    Huber, T.B.3
  • 47
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: A unifying view of glomerular diseases
    • Wiggins RC, (2007) The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int 71: 1205-1214
    • (2007) Kidney Int , vol.71 , pp. 1205-1214
    • Wiggins, R.C.1
  • 48
    • 22244466451 scopus 로고    scopus 로고
    • Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex
    • Lehtonen S, Ryan JJ, Kudlicka K, Iino N, Zhou H, Farquhar MG, (2005) Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex. Proc Natl Acad Sci U S A 102: 9814-9819
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9814-9819
    • Lehtonen, S.1    Ryan, J.J.2    Kudlicka, K.3    Iino, N.4    Zhou, H.5    Farquhar, M.G.6
  • 49
    • 84861469119 scopus 로고    scopus 로고
    • IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro
    • Rigothier C, Auguste P, Welsh GI, Lepreux S, Deminiere C, Mathieson PW, Saleem MA, Ripoche J, Combe C, (2012) IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro. PLoS ONE 7: e37695
    • (2012) PLoS ONE , vol.7 , pp. e37695
    • Rigothier, C.1    Auguste, P.2    Welsh, G.I.3    Lepreux, S.4    Deminiere, C.5    Mathieson, P.W.6    Saleem, M.A.7    Ripoche, J.8    Combe, C.9
  • 50
    • 77953878405 scopus 로고    scopus 로고
    • Adherens junctions: From molecules to morphogenesis
    • Harris TJ, Tepass U, (2010) Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol 11: 502-514
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 502-514
    • Harris, T.J.1    Tepass, U.2
  • 51
    • 34548269154 scopus 로고    scopus 로고
    • N-cadherin regulates cytoskeletally associated IQGAP1/ERK signaling and memory formation
    • Schrick C, Fischer A, Srivastava DP, Tronson NC, Penzes P, Radulovic J, (2007) N-cadherin regulates cytoskeletally associated IQGAP1/ERK signaling and memory formation. Neuron 55: 786-798
    • (2007) Neuron , vol.55 , pp. 786-798
    • Schrick, C.1    Fischer, A.2    Srivastava, D.P.3    Tronson, N.C.4    Penzes, P.5    Radulovic, J.6
  • 53
    • 0036510761 scopus 로고    scopus 로고
    • IQGAP1-mediated stimulation of transcriptional co-activation by β-catenin is modulated by calmodulin
    • Briggs MW, Li Z, Sacks DB, (2002) IQGAP1-mediated stimulation of transcriptional co-activation by β-catenin is modulated by calmodulin. J Biol Chem 277: 7453-7465
    • (2002) J Biol Chem , vol.277 , pp. 7453-7465
    • Briggs, M.W.1    Li, Z.2    Sacks, D.B.3
  • 55
    • 53349110116 scopus 로고    scopus 로고
    • Therapeutical relevance of MAP-kinase inhibitors in renal diseases: Current knowledge and future clinical perspectives
    • Grande MT, Lopez-Novoa JM, (2008) Therapeutical relevance of MAP-kinase inhibitors in renal diseases: current knowledge and future clinical perspectives. Curr Med Chem 15: 2054-2070
    • (2008) Curr Med Chem , vol.15 , pp. 2054-2070
    • Grande, M.T.1    Lopez-Novoa, J.M.2
  • 56
    • 84889658289 scopus 로고    scopus 로고
    • IQGAP1 mediates angiotensin II-induced apoptosis of podocytes via the ERK1/2 MAPK signaling pathway
    • Liu Y, Liang W, Yang Q, Ren Z, Chen X, Zha D, Singhal PC, Ding G, (2013) IQGAP1 mediates angiotensin II-induced apoptosis of podocytes via the ERK1/2 MAPK signaling pathway. Am J Nephrol 38: 430-444
    • (2013) Am J Nephrol , vol.38 , pp. 430-444
    • Liu, Y.1    Liang, W.2    Yang, Q.3    Ren, Z.4    Chen, X.5    Zha, D.6    Singhal, P.C.7    Ding, G.8
  • 60
    • 0037192854 scopus 로고    scopus 로고
    • Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cells
    • Hellberg CB, Burden-Gulley SM, Pietz GE, Brady-Kalnay SM, (2002) Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cells. J Biol Chem 277: 11165-11173
    • (2002) J Biol Chem , vol.277 , pp. 11165-11173
    • Hellberg, C.B.1    Burden-Gulley, S.M.2    Pietz, G.E.3    Brady-Kalnay, S.M.4
  • 61
    • 0037847431 scopus 로고    scopus 로고
    • 2+, calmodulin, Cdc42 and the cytoskeleton
    • 2+, calmodulin, Cdc42 and the cytoskeleton. FEBS Lett 542: 7-11
    • (2003) FEBS Lett , vol.542 , pp. 7-11
    • Briggs, M.W.1    Sacks, D.B.2
  • 64
    • 78049276672 scopus 로고    scopus 로고
    • Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies
    • Wynshaw-Boris A, Pramparo T, Youn YH, Hirotsune S, (2010) Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies. Semin Cell Dev Biol 21: 823-830
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 823-830
    • Wynshaw-Boris, A.1    Pramparo, T.2    Youn, Y.H.3    Hirotsune, S.4
  • 65
    • 0037015059 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
    • Jin K, Zhu Y, Sun Y, Mao XO, Xie L, Greenberg DA, (2002) Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci U S A 99: 11946-11950
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11946-11950
    • Jin, K.1    Zhu, Y.2    Sun, Y.3    Mao, X.O.4    Xie, L.5    Greenberg, D.A.6
  • 66
    • 34247543119 scopus 로고    scopus 로고
    • IQGAP1 regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro
    • Balenci L, Saoudi Y, Grunwald D, Deloulme JC, Bouron A, Bernards A, Baudier J, (2007) IQGAP1 regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro. J Neurosci 27: 4716-4724
    • (2007) J Neurosci , vol.27 , pp. 4716-4724
    • Balenci, L.1    Saoudi, Y.2    Grunwald, D.3    Deloulme, J.C.4    Bouron, A.5    Bernards, A.6    Baudier, J.7
  • 70
    • 84880834728 scopus 로고    scopus 로고
    • Molecular mechanisms of dendrite stability
    • Koleske AJ, (2013) Molecular mechanisms of dendrite stability. Nat Rev Neurosci 14: 536-550
    • (2013) Nat Rev Neurosci , vol.14 , pp. 536-550
    • Koleske, A.J.1
  • 73
    • 0034730790 scopus 로고    scopus 로고
    • Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart
    • Franchini KG, Torsoni AS, Soares PH, Saad MJ, (2000) Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart. Circ Res 87: 558-565
    • (2000) Circ Res , vol.87 , pp. 558-565
    • Franchini, K.G.1    Torsoni, A.S.2    Soares, P.H.3    Saad, M.J.4
  • 74
    • 0036084426 scopus 로고    scopus 로고
    • Load-induced focal adhesion kinase activation in the myocardium: Role of stretch and contractile activity
    • Domingos PP, Fonseca PM, Nadruz W Jr, Franchini KG, (2002) Load-induced focal adhesion kinase activation in the myocardium: role of stretch and contractile activity. Am J Physiol Heart Circ Physiol 282: H556-H564
    • (2002) Am J Physiol Heart Circ Physiol , vol.282 , pp. H556-H564
    • Domingos, P.P.1    Fonseca, P.M.2    Nadruz, Jr.W.3    Franchini, K.G.4
  • 77
    • 4043148481 scopus 로고    scopus 로고
    • IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species-dependent endothelial migration and proliferation
    • Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, et al, (2004) IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species-dependent endothelial migration and proliferation. Circ Res 95: 276-283
    • (2004) Circ Res , vol.95 , pp. 276-283
    • Yamaoka-Tojo, M.1    Ushio-Fukai, M.2    Hilenski, L.3    Dikalov, S.I.4    Chen, Y.E.5    Tojo, T.6    Fukai, T.7    Fujimoto, M.8    Patrushev, N.A.9    Wang, N.10
  • 78
    • 57349159403 scopus 로고    scopus 로고
    • IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis
    • Meyer RD, Sacks DB, Rahimi N, (2008) IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis. PLoS ONE 3: e3848
    • (2008) PLoS ONE , vol.3 , pp. e3848
    • Meyer, R.D.1    Sacks, D.B.2    Rahimi, N.3
  • 79
    • 84884373913 scopus 로고    scopus 로고
    • IQGAP1 links PDGF receptor-beta signal to focal adhesions involved in vascular smooth muscle cell migration: Role in neointimal formation after vascular injury
    • Kohno T, Urao N, Ashino T, Sudhahar V, Inomata H, Yamaoka-Tojo M, McKinney RD, Fukai T, Ushio-Fukai M, (2013) IQGAP1 links PDGF receptor-beta signal to focal adhesions involved in vascular smooth muscle cell migration: role in neointimal formation after vascular injury. Am J Physiol Cell Physiol 305: C591-C600
    • (2013) Am J Physiol Cell Physiol , vol.305 , pp. C591-C600
    • Kohno, T.1    Urao, N.2    Ashino, T.3    Sudhahar, V.4    Inomata, H.5    Yamaoka-Tojo, M.6    McKinney, R.D.7    Fukai, T.8    Ushio-Fukai, M.9
  • 80
    • 38149036613 scopus 로고    scopus 로고
    • IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
    • Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB, (2008) IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem 283: 1008-1017
    • (2008) J Biol Chem , vol.283 , pp. 1008-1017
    • Jadeski, L.1    Mataraza, J.M.2    Jeong, H.W.3    Li, Z.4    Sacks, D.B.5
  • 81
  • 82
    • 80054953975 scopus 로고    scopus 로고
    • Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense
    • David S, Ghosh CC, Mukherjee A, Parikh SM, (2011) Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense. Arterioscler Thromb Vasc Biol 31: 2643-2652
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2643-2652
    • David, S.1    Ghosh, C.C.2    Mukherjee, A.3    Parikh, S.M.4
  • 86
    • 84896708893 scopus 로고    scopus 로고
    • IQ domain GTPase-activating protein 1 is involved in shear stress-induced progenitor-derived endothelial cell alignment
    • Rami L, Auguste P, Thebaud NB, Bareille R, Daculsi R, Ripoche J, Bordenave L, (2013) IQ domain GTPase-activating protein 1 is involved in shear stress-induced progenitor-derived endothelial cell alignment. PLoS ONE 8: e79919
    • (2013) PLoS ONE , vol.8 , pp. e79919
    • Rami, L.1    Auguste, P.2    Thebaud, N.B.3    Bareille, R.4    Daculsi, R.5    Ripoche, J.6    Bordenave, L.7
  • 87
    • 0141751697 scopus 로고    scopus 로고
    • Calcium sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • Somlyo AP, Somlyo AV, (2003) Calcium sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1358
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 88
    • 73949121819 scopus 로고    scopus 로고
    • Regulation of smooth muscle contraction by small GTPases
    • Puetz S, Lubomirov LT, Pfitzer G, (2009) Regulation of smooth muscle contraction by small GTPases. Physiology 24: 342-356
    • (2009) Physiology , vol.24 , pp. 342-356
    • Puetz, S.1    Lubomirov, L.T.2    Pfitzer, G.3
  • 90
    • 79957900616 scopus 로고    scopus 로고
    • Dynamics of insulin secretion and the clinical implications for obesity and diabetes
    • Seino S, Shibasaki T, Minami K, (2011) Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J Clin Invest 121: 2118-2125
    • (2011) J Clin Invest , vol.121 , pp. 2118-2125
    • Seino, S.1    Shibasaki, T.2    Minami, K.3
  • 94
    • 84926255482 scopus 로고    scopus 로고
    • Interactome analysis of AMP-activated protein kinase (AMPK)-alpha1 and -beta1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry
    • Moon S, Han D, Kim Y, Jin J, Ho WK, (2014) Interactome analysis of AMP-activated protein kinase (AMPK)-alpha1 and -beta1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry. Sci Rep 4: 4376
    • (2014) Sci Rep , vol.4 , pp. 4376
    • Moon, S.1    Han, D.2    Kim, Y.3    Jin, J.4    Ho, W.K.5
  • 95
    • 83255176779 scopus 로고    scopus 로고
    • Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake
    • Chiariello CS, LaComb JF, Bahou WF, Schmidt VA, (2011) Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake. Regul Pept 173: 36-46
    • (2011) Regul Pept , vol.173 , pp. 36-46
    • Chiariello, C.S.1    Lacomb, J.F.2    Bahou, W.F.3    Schmidt, V.A.4
  • 97
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert S, Shannon K, Bollag G, (2007) Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 7: 295-308
    • (2007) Nat Rev Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 98
    • 84887478023 scopus 로고    scopus 로고
    • Tumor adaptation and resistance to RAF inhibitors
    • Lito P, Rosen N, Solit DB, (2013) Tumor adaptation and resistance to RAF inhibitors. Nat Med 19: 1401-1409
    • (2013) Nat Med , vol.19 , pp. 1401-1409
    • Lito, P.1    Rosen, N.2    Solit, D.B.3
  • 99
    • 67649240282 scopus 로고    scopus 로고
    • IQGAP1 regulation and roles in cancer
    • Johnson M, Sharma M, Henderson BR, (2009) IQGAP1 regulation and roles in cancer. Cell Signal 21: 1471-1478
    • (2009) Cell Signal , vol.21 , pp. 1471-1478
    • Johnson, M.1    Sharma, M.2    Henderson, B.R.3
  • 100
    • 67349198476 scopus 로고    scopus 로고
    • IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis
    • White CD, Brown MD, Sacks DB, (2009) IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis. FEBS Lett 583: 1817-1824
    • (2009) FEBS Lett , vol.583 , pp. 1817-1824
    • White, C.D.1    Brown, M.D.2    Sacks, D.B.3
  • 103
    • 84857712365 scopus 로고    scopus 로고
    • Protein-protein interaction inhibitors get into the groove
    • Mullard A, (2012) Protein-protein interaction inhibitors get into the groove. Nat Rev Drug Discov 11: 173-175
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 173-175
    • Mullard, A.1
  • 104
    • 84909587217 scopus 로고    scopus 로고
    • Small-molecule inhibitors of protein-protein interactions: Progressing toward the reality
    • Arkin MR, Tang Y, Wells JA, (2014) Small-molecule inhibitors of protein-protein interactions: progressing toward the reality. Chem Biol 21: 1102-1114
    • (2014) Chem Biol , vol.21 , pp. 1102-1114
    • Arkin, M.R.1    Tang, Y.2    Wells, J.A.3
  • 105
    • 0033961250 scopus 로고    scopus 로고
    • Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1
    • Li S, Wang Q, Chakladar A, Bronson RT, Bernards A, (2000) Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1. Mol Cell Biol 20: 697-701
    • (2000) Mol Cell Biol , vol.20 , pp. 697-701
    • Li, S.1    Wang, Q.2    Chakladar, A.3    Bronson, R.T.4    Bernards, A.5
  • 106
    • 35348992048 scopus 로고    scopus 로고
    • Manipulation of host-cell pathways by bacterial pathogens
    • Bhavsar AP, Guttman JA, Finlay BB, (2007) Manipulation of host-cell pathways by bacterial pathogens. Nature 449: 827-834
    • (2007) Nature , vol.449 , pp. 827-834
    • Bhavsar, A.P.1    Guttman, J.A.2    Finlay, B.B.3
  • 107
    • 58049216318 scopus 로고    scopus 로고
    • Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin
    • Brown MD, Bry L, Li Z, Sacks DB, (2008) Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin. J Biol Chem 283: 35212-35222
    • (2008) J Biol Chem , vol.283 , pp. 35212-35222
    • Brown, M.D.1    Bry, L.2    Li, Z.3    Sacks, D.B.4
  • 108
    • 62149140232 scopus 로고    scopus 로고
    • Identification and characterization of Ibe, a novel type III effector protein of A/E pathogens targeting human IQGAP1
    • Buss C, Muller D, Ruter C, Heusipp G, Schmidt MA, (2009) Identification and characterization of Ibe, a novel type III effector protein of A/E pathogens targeting human IQGAP1. Cell Microbiol 11: 661-677
    • (2009) Cell Microbiol , vol.11 , pp. 661-677
    • Buss, C.1    Muller, D.2    Ruter, C.3    Heusipp, G.4    Schmidt, M.A.5
  • 109
    • 84865319107 scopus 로고    scopus 로고
    • IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells
    • Krishnan S, Fernandez GE, Sacks DB, Prasadarao NV, (2012) IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells. Cell Microbiol 14: 1415-1433
    • (2012) Cell Microbiol , vol.14 , pp. 1415-1433
    • Krishnan, S.1    Fernandez, G.E.2    Sacks, D.B.3    Prasadarao, N.V.4
  • 110
    • 35648942810 scopus 로고    scopus 로고
    • IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1 and Cdc42
    • Brown MD, Bry L, Li Z, Sacks DB, (2007) IQGAP1 regulates Salmonella invasion through interactions with actin, Rac1 and Cdc42. J Biol Chem 282: 30265-30272
    • (2007) J Biol Chem , vol.282 , pp. 30265-30272
    • Brown, M.D.1    Bry, L.2    Li, Z.3    Sacks, D.B.4
  • 112
    • 82455220362 scopus 로고    scopus 로고
    • Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling
    • Kim H, White CD, Li Z, Sacks DB, (2011) Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling. Biochem J 440: 309-318
    • (2011) Biochem J , vol.440 , pp. 309-318
    • Kim, H.1    White, C.D.2    Li, Z.3    Sacks, D.B.4
  • 113
    • 84867355751 scopus 로고    scopus 로고
    • Chlamydophila (Chlamydia) pneumoniae infection promotes vascular smooth muscle cell adhesion and migration through IQ domain GTPase-activating protein 1
    • Zhang L, Li X, Wang B, Zhang T, Ye J, (2012) Chlamydophila (Chlamydia) pneumoniae infection promotes vascular smooth muscle cell adhesion and migration through IQ domain GTPase-activating protein 1. Microb Pathog 53: 207-213
    • (2012) Microb Pathog , vol.53 , pp. 207-213
    • Zhang, L.1    Li, X.2    Wang, B.3    Zhang, T.4    Ye, J.5
  • 114
    • 84868146992 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration
    • Karlsson T, Turkina MV, Yakymenko O, Magnusson KE, Vikstrom E, (2012) The Pseudomonas aeruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration. PLoS Pathog 8: e1002953
    • (2012) PLoS Pathog , vol.8 , pp. e1002953
    • Karlsson, T.1    Turkina, M.V.2    Yakymenko, O.3    Magnusson, K.E.4    Vikstrom, E.5
  • 115
    • 84877279350 scopus 로고    scopus 로고
    • Platforms for antibiotic discovery
    • Lewis K, (2013) Platforms for antibiotic discovery. Nat Rev Drug Discov 12: 371-387
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 371-387
    • Lewis, K.1
  • 116
    • 0038314400 scopus 로고    scopus 로고
    • Virus entry, assembly, budding, and membrane rafts
    • Chazal N, Gerlier D, (2003) Virus entry, assembly, budding, and membrane rafts. Microbiol Mol Biol Rev 67: 226-237
    • (2003) Microbiol Mol Biol Rev , vol.67 , pp. 226-237
    • Chazal, N.1    Gerlier, D.2
  • 117
  • 119
  • 120
  • 121
    • 84908342915 scopus 로고    scopus 로고
    • Interaction with tsg101 is necessary for the efficient transport and release of nucleocapsids in Marburg virus-infected cells
    • Dolnik O, Kolesnikova L, Welsch S, Strecker T, Schudt G, Becker S, (2014) Interaction with tsg101 is necessary for the efficient transport and release of nucleocapsids in Marburg virus-infected cells. PLoS Pathog 10: e1004463
    • (2014) PLoS Pathog , vol.10 , pp. e1004463
    • Dolnik, O.1    Kolesnikova, L.2    Welsch, S.3    Strecker, T.4    Schudt, G.5    Becker, S.6
  • 122
    • 84897112785 scopus 로고    scopus 로고
    • Regulation of Akt signaling by sirtuins: Its implication in cardiac hypertrophy and aging
    • Pillai VB, Sundaresan NR, Gupta MP, (2014) Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. Circ Res 114: 368-378
    • (2014) Circ Res , vol.114 , pp. 368-378
    • Pillai, V.B.1    Sundaresan, N.R.2    Gupta, M.P.3
  • 125
    • 79953216184 scopus 로고    scopus 로고
    • IQ-motif selectivity in human IQGAP2 and IQGAP3: Binding of calmodulin and myosin essential light chain
    • Atcheson E, Hamilton E, Pathmanathan S, Greer B, Harriott P, Timson DJ, (2011) IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain. Biosci Rep 31: 371-379
    • (2011) Biosci Rep , vol.31 , pp. 371-379
    • Atcheson, E.1    Hamilton, E.2    Pathmanathan, S.3    Greer, B.4    Harriott, P.5    Timson, D.J.6
  • 126
    • 0029784514 scopus 로고    scopus 로고
    • The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases
    • Brill S, Li S, Lyman CW, Church DM, Wasmuth JJ, Weissbach L, Bernards A, Snijders AJ, (1996) The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases. Mol Cell Biol 16: 4869-4878
    • (1996) Mol Cell Biol , vol.16 , pp. 4869-4878
    • Brill, S.1    Li, S.2    Lyman, C.W.3    Church, D.M.4    Wasmuth, J.J.5    Weissbach, L.6    Bernards, A.7    Snijders, A.J.8
  • 127
    • 0038620337 scopus 로고    scopus 로고
    • IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization
    • Schmidt VA, Scudder L, Devoe CE, Bernards A, Cupit LD, Bahou WF, (2003) IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood 101: 3021-3028
    • (2003) Blood , vol.101 , pp. 3021-3028
    • Schmidt, V.A.1    Scudder, L.2    Devoe, C.E.3    Bernards, A.4    Cupit, L.D.5    Bahou, W.F.6
  • 128
    • 84901309518 scopus 로고    scopus 로고
    • IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells
    • Yang Y, Zhao W, Xu QW, Wang XS, Zhang Y, Zhang J, (2014) IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells. PLoS ONE 9: e97578
    • (2014) PLoS ONE , vol.9 , pp. e97578
    • Yang, Y.1    Zhao, W.2    Xu, Q.W.3    Wang, X.S.4    Zhang, Y.5    Zhang, J.6
  • 132
    • 15744404625 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression
    • Bourguignon LY, Gilad E, Rothman K, Peyrollier K, (2005) Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression. J Biol Chem 280: 11961-11972
    • (2005) J Biol Chem , vol.280 , pp. 11961-11972
    • Bourguignon, L.Y.1    Gilad, E.2    Rothman, K.3    Peyrollier, K.4
  • 136
    • 67649304855 scopus 로고    scopus 로고
    • Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells
    • Usatyuk PV, Gorshkova IA, He D, Zhao Y, Kalari SK, Garcia JG, Natarajan V, (2009) Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells. J Biol Chem 284: 15339-15352
    • (2009) J Biol Chem , vol.284 , pp. 15339-15352
    • Usatyuk, P.V.1    Gorshkova, I.A.2    He, D.3    Zhao, Y.4    Kalari, S.K.5    Garcia, J.G.6    Natarajan, V.7
  • 137
    • 84893875999 scopus 로고    scopus 로고
    • Conserved sequence repeats of IQGAP1 mediate binding to Ezrin
    • Liu J, Guidry JJ, Worthylake DK, (2013) Conserved sequence repeats of IQGAP1 mediate binding to Ezrin. J Proteome Res 13: 1156-1166
    • (2013) J Proteome Res , vol.13 , pp. 1156-1166
    • Liu, J.1    Guidry, J.J.2    Worthylake, D.K.3
  • 138
    • 77957682469 scopus 로고    scopus 로고
    • TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
    • Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK, (2010) TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev 24: 2180-2193
    • (2010) Genes Dev , vol.24 , pp. 2180-2193
    • Mukhopadhyay, S.1    Wen, X.2    Chih, B.3    Nelson, C.D.4    Lane, W.S.5    Scales, S.J.6    Jackson, P.K.7
  • 139
    • 40849108777 scopus 로고    scopus 로고
    • Mapping the integrin-linked kinase interactome using SILAC
    • Dobreva I, Fielding A, Foster LJ, Dedhar S, (2008) Mapping the integrin-linked kinase interactome using SILAC. J Proteome Res 7: 1740-1749
    • (2008) J Proteome Res , vol.7 , pp. 1740-1749
    • Dobreva, I.1    Fielding, A.2    Foster, L.J.3    Dedhar, S.4
  • 143
    • 79961135745 scopus 로고    scopus 로고
    • Protein 4.1R regulates cell migration and IQGAP1 recruitment to the leading edge
    • Ruiz-Saenz A, Kremer L, Alonso MA, Millan J, Correas I, (2011) Protein 4.1R regulates cell migration and IQGAP1 recruitment to the leading edge. J Cell Sci 124: 2529-2538
    • (2011) J Cell Sci , vol.124 , pp. 2529-2538
    • Ruiz-Saenz, A.1    Kremer, L.2    Alonso, M.A.3    Millan, J.4    Correas, I.5
  • 144
    • 10044238907 scopus 로고    scopus 로고
    • Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis
    • Lui WY, Mruk DD, Cheng CY, (2005) Interactions among IQGAP1, Cdc42, and the cadherin/catenin protein complex regulate Sertoli-germ cell adherens junction dynamics in the testis. J Cell Physiol 202: 49-66
    • (2005) J Cell Physiol , vol.202 , pp. 49-66
    • Lui, W.Y.1    Mruk, D.D.2    Cheng, C.Y.3
  • 145
    • 45049085512 scopus 로고    scopus 로고
    • Requirement of kinesin-mediated membrane transport of WAVE2 along microtubules for lamellipodia formation promoted by hepatocyte growth factor
    • Takahashi K, Suzuki K, (2008) Requirement of kinesin-mediated membrane transport of WAVE2 along microtubules for lamellipodia formation promoted by hepatocyte growth factor. Exp Cell Res 314: 2313-2322
    • (2008) Exp Cell Res , vol.314 , pp. 2313-2322
    • Takahashi, K.1    Suzuki, K.2
  • 146
    • 9644268123 scopus 로고    scopus 로고
    • Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A
    • Nakajima E, Suzuki K, Takahashi K, (2005) Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A. Biochem Biophys Res Commun 326: 249-253
    • (2005) Biochem Biophys Res Commun , vol.326 , pp. 249-253
    • Nakajima, E.1    Suzuki, K.2    Takahashi, K.3
  • 150
    • 0038708352 scopus 로고    scopus 로고
    • Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells
    • Katata T, Irie K, Fukuhara A, Kawakatsu T, Yamada A, Shimizu K, Takai Y, (2003) Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells. Oncogene 22: 2097-2109
    • (2003) Oncogene , vol.22 , pp. 2097-2109
    • Katata, T.1    Irie, K.2    Fukuhara, A.3    Kawakatsu, T.4    Yamada, A.5    Shimizu, K.6    Takai, Y.7
  • 152
    • 0032500751 scopus 로고    scopus 로고
    • Binding of myosin essential light chain to the cytoskeleton-associated protein IQGAP1
    • Weissbach L, Bernards A, Herion DW, (1998) Binding of myosin essential light chain to the cytoskeleton-associated protein IQGAP1. Biochem Biophys Res Commun 251: 269-276
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 269-276
    • Weissbach, L.1    Bernards, A.2    Herion, D.W.3
  • 153
    • 0037147160 scopus 로고    scopus 로고
    • The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes
    • Mbele GO, Deloulme JC, Gentil BJ, Delphin C, Ferro M, Garin J, Takahashi M, Baudier J, (2002) The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes. J Biol Chem 277: 49998-50007
    • (2002) J Biol Chem , vol.277 , pp. 49998-50007
    • Mbele, G.O.1    Deloulme, J.C.2    Gentil, B.J.3    Delphin, C.4    Ferro, M.5    Garin, J.6    Takahashi, M.7    Baudier, J.8
  • 155
    • 0037337310 scopus 로고    scopus 로고
    • A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling
    • Blagoev B, Kratchmarova I, Ong SE, Nielsen M, Foster LJ, Mann M, (2003) A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. Nat Biotechnol 21: 315-318
    • (2003) Nat Biotechnol , vol.21 , pp. 315-318
    • Blagoev, B.1    Kratchmarova, I.2    Ong, S.E.3    Nielsen, M.4    Foster, L.J.5    Mann, M.6
  • 156
    • 79955440704 scopus 로고    scopus 로고
    • MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation
    • McNulty DE, Li Z, White CD, Sacks DB, Annan RS, (2011) MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation. J Biol Chem 286: 15010-15021
    • (2011) J Biol Chem , vol.286 , pp. 15010-15021
    • McNulty, D.E.1    Li, Z.2    White, C.D.3    Sacks, D.B.4    Annan, R.S.5
  • 157
    • 80051932950 scopus 로고    scopus 로고
    • IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance
    • White CD, Li Z, Dillon DA, Sacks DB, (2011) IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance. J Biol Chem 286: 29734-29747
    • (2011) J Biol Chem , vol.286 , pp. 29734-29747
    • White, C.D.1    Li, Z.2    Dillon, D.A.3    Sacks, D.B.4
  • 160
    • 80051856620 scopus 로고    scopus 로고
    • IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse"
    • Neel NF, Sai J, Ham AJ, Sobolik-Delmaire T, Mernaugh RL, Richmond A, (2011) IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse". PLoS ONE 6: e23813
    • (2011) PLoS ONE , vol.6 , pp. e23813
    • Neel, N.F.1    Sai, J.2    Ham, A.J.3    Sobolik-Delmaire, T.4    Mernaugh, R.L.5    Richmond, A.6
  • 161
    • 84896528786 scopus 로고    scopus 로고
    • G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
    • Feigin ME, Xue B, Hammell MC, Muthuswamy SK, (2014) G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. Proc Natl Acad Sci U S A 111: 4191-4196
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 4191-4196
    • Feigin, M.E.1    Xue, B.2    Hammell, M.C.3    Muthuswamy, S.K.4
  • 164
    • 26844443598 scopus 로고    scopus 로고
    • Phosphorylation-dependent interactions of alpha-Actinin-1/IQGAP1 with the AMPA receptor subunit GluR4
    • Nuriya M, Oh S, Huganir RL, (2005) Phosphorylation-dependent interactions of alpha-Actinin-1/IQGAP1 with the AMPA receptor subunit GluR4. J Neurochem 95: 544-552
    • (2005) J Neurochem , vol.95 , pp. 544-552
    • Nuriya, M.1    Oh, S.2    Huganir, R.L.3
  • 166
    • 84885177444 scopus 로고    scopus 로고
    • IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration
    • Choi S, Thapa N, Hedman AC, Li Z, Sacks DB, Anderson RA, (2013) IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration. EMBO J 32: 2617-2630
    • (2013) EMBO J , vol.32 , pp. 2617-2630
    • Choi, S.1    Thapa, N.2    Hedman, A.C.3    Li, Z.4    Sacks, D.B.5    Anderson, R.A.6
  • 169
    • 79955974141 scopus 로고    scopus 로고
    • Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification
    • Gunaratne J, Goh MX, Swa HL, Lee FY, Sanford E, Wong LM, Hogue KA, Blackstock WP, Okumura K, (2011) Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification. J Biol Chem 286: 18093-18103
    • (2011) J Biol Chem , vol.286 , pp. 18093-18103
    • Gunaratne, J.1    Goh, M.X.2    Swa, H.L.3    Lee, F.Y.4    Sanford, E.5    Wong, L.M.6    Hogue, K.A.7    Blackstock, W.P.8    Okumura, K.9
  • 170
    • 84863107745 scopus 로고    scopus 로고
    • A conserved role of IQGAP1 in regulating TOR complex 1
    • Tekletsadik YK, Sonn R, Osman MA, (2012) A conserved role of IQGAP1 in regulating TOR complex 1. J Cell Sci 125: 2041-2052
    • (2012) J Cell Sci , vol.125 , pp. 2041-2052
    • Tekletsadik, Y.K.1    Sonn, R.2    Osman, M.A.3
  • 171
    • 73449124046 scopus 로고    scopus 로고
    • TNFalpha induced oxidative stress dependent Akt signaling affects actin cytoskeletal organization in glioma cells
    • Ghosh S, Tewari R, Dixit D, Sen E, (2009) TNFalpha induced oxidative stress dependent Akt signaling affects actin cytoskeletal organization in glioma cells. Neurochem Int 56: 194-201
    • (2009) Neurochem Int , vol.56 , pp. 194-201
    • Ghosh, S.1    Tewari, R.2    Dixit, D.3    Sen, E.4
  • 172
    • 77955833744 scopus 로고    scopus 로고
    • IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation
    • Chen F, Zhu HH, Zhou LF, Wu SS, Wang J, Chen Z, (2010) IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation. Exp Mol Med 42: 477-483
    • (2010) Exp Mol Med , vol.42 , pp. 477-483
    • Chen, F.1    Zhu, H.H.2    Zhou, L.F.3    Wu, S.S.4    Wang, J.5    Chen, Z.6
  • 174
    • 33744912491 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II
    • 2+/calmodulin-dependent protein kinase II. J Cell Physiol 208: 213-219
    • (2006) J Cell Physiol , vol.208 , pp. 213-219
    • Takahashi, K.1    Suzuki, K.2
  • 175
    • 84903278256 scopus 로고    scopus 로고
    • A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions
    • Fram S, King H, Sacks DB, Wells CM, (2014) A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions. Cell Mol Life Sci 71: 2759-2773
    • (2014) Cell Mol Life Sci , vol.71 , pp. 2759-2773
    • Fram, S.1    King, H.2    Sacks, D.B.3    Wells, C.M.4
  • 176
    • 51649097710 scopus 로고    scopus 로고
    • Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins
    • Kaur R, Yuan X, Lu ML, Balk SP, (2008) Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins. Prostate 68: 1510-1516
    • (2008) Prostate , vol.68 , pp. 1510-1516
    • Kaur, R.1    Yuan, X.2    Lu, M.L.3    Balk, S.P.4
  • 177
    • 0041319417 scopus 로고    scopus 로고
    • Identification of an IQGAP1/AKAP79 complex in beta-cells
    • Nauert JB, Rigas JD, Lester LB, (2003) Identification of an IQGAP1/AKAP79 complex in beta-cells. J Cell Biochem 90: 97-108
    • (2003) J Cell Biochem , vol.90 , pp. 97-108
    • Nauert, J.B.1    Rigas, J.D.2    Lester, L.B.3
  • 178
    • 10344260216 scopus 로고    scopus 로고
    • Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator
    • Grohmanova K, Schlaepfer D, Hess D, Gutierrez P, Beck M, Kroschewski R, (2004) Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator. J Biol Chem 279: 48495-48504
    • (2004) J Biol Chem , vol.279 , pp. 48495-48504
    • Grohmanova, K.1    Schlaepfer, D.2    Hess, D.3    Gutierrez, P.4    Beck, M.5    Kroschewski, R.6
  • 179
    • 18244377646 scopus 로고    scopus 로고
    • Requirement of protein phosphatase 2A for recruitment of IQGAP1 to Rac-bound beta1 integrin
    • Suzuki K, Chikamatsu Y, Takahashi K, (2005) Requirement of protein phosphatase 2A for recruitment of IQGAP1 to Rac-bound beta1 integrin. J Cell Physiol 203: 487-492
    • (2005) J Cell Physiol , vol.203 , pp. 487-492
    • Suzuki, K.1    Chikamatsu, Y.2    Takahashi, K.3
  • 180
    • 3543035767 scopus 로고    scopus 로고
    • Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
    • Meek SE, Lane WS, Piwnica-Worms H, (2004) Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. J Biol Chem 279: 32046-32054
    • (2004) J Biol Chem , vol.279 , pp. 32046-32054
    • Meek, S.E.1    Lane, W.S.2    Piwnica-Worms, H.3
  • 182
    • 33847372478 scopus 로고    scopus 로고
    • Characterization of IQGAP1-containing complexes in NK-like cells: Evidence for Rac2 and RACK1 association during homotypic adhesion
    • Meng X, Krokhin O, Cheng K, Ens W, Wilkins JA, (2007) Characterization of IQGAP1-containing complexes in NK-like cells: evidence for Rac2 and RACK1 association during homotypic adhesion. J Proteome Res 6: 744-750
    • (2007) J Proteome Res , vol.6 , pp. 744-750
    • Meng, X.1    Krokhin, O.2    Cheng, K.3    Ens, W.4    Wilkins, J.A.5
  • 184
    • 59149105836 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway
    • Hu B, Shi B, Jarzynka MJ, Yiin JJ, D'Souza-Schorey C, Cheng SY, (2009) ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res 69: 794-801
    • (2009) Cancer Res , vol.69 , pp. 794-801
    • Hu, B.1    Shi, B.2    Jarzynka, M.J.3    Yiin, J.J.4    D'Souza-Schorey, C.5    Cheng, S.Y.6
  • 186
    • 84903549576 scopus 로고    scopus 로고
    • The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts
    • Steenblock C, Heckel T, Czupalla C, Santo AI, Niehage C, Sztacho M, Hoflack B, (2014) The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts. J Biol Chem 289: 18347-18359
    • (2014) J Biol Chem , vol.289 , pp. 18347-18359
    • Steenblock, C.1    Heckel, T.2    Czupalla, C.3    Santo, A.I.4    Niehage, C.5    Sztacho, M.6    Hoflack, B.7
  • 187
    • 80054933395 scopus 로고    scopus 로고
    • The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
    • Liu Z, Lee J, Krummey S, Lu W, Cai H, Lenardo MJ, (2011) The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease. Nat Immunol 12: 1063-1070
    • (2011) Nat Immunol , vol.12 , pp. 1063-1070
    • Liu, Z.1    Lee, J.2    Krummey, S.3    Lu, W.4    Cai, H.5    Lenardo, M.J.6
  • 188
    • 10644254712 scopus 로고    scopus 로고
    • Identification of protein-protein interactions using in vivo cross-linking and mass spectrometry
    • Vasilescu J, Guo X, Kast J, (2004) Identification of protein-protein interactions using in vivo cross-linking and mass spectrometry. Proteomics 4: 3845-3854
    • (2004) Proteomics , vol.4 , pp. 3845-3854
    • Vasilescu, J.1    Guo, X.2    Kast, J.3
  • 190
    • 84890957222 scopus 로고    scopus 로고
    • IQGAP1 protein regulates nuclear localization of beta-catenin via importin-beta5 protein in Wnt signaling
    • Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H, (2013) IQGAP1 protein regulates nuclear localization of beta-catenin via importin-beta5 protein in Wnt signaling. J Biol Chem 288: 36351-36360
    • (2013) J Biol Chem , vol.288 , pp. 36351-36360
    • Goto, T.1    Sato, A.2    Adachi, S.3    Iemura, S.4    Natsume, T.5    Shibuya, H.6
  • 191
    • 34547103558 scopus 로고    scopus 로고
    • IQGAP1 binds Rap1 and modulates its activity
    • Jeong HW, Li Z, Brown MD, Sacks DB, (2007) IQGAP1 binds Rap1 and modulates its activity. J Biol Chem 282: 20752-20762
    • (2007) J Biol Chem , vol.282 , pp. 20752-20762
    • Jeong, H.W.1    Li, Z.2    Brown, M.D.3    Sacks, D.B.4
  • 193
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark EA, Golub TR, Lander ES, Hynes RO, (2000) Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406: 532-535
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 194
    • 79957661591 scopus 로고    scopus 로고
    • RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1
    • Wu Y, Chen YC, Sang JR, Xu WR, (2011) RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1. Mol Med Rep 4: 697-703
    • (2011) Mol Med Rep , vol.4 , pp. 697-703
    • Wu, Y.1    Chen, Y.C.2    Sang, J.R.3    Xu, W.R.4
  • 195
    • 0032558696 scopus 로고    scopus 로고
    • Distinct cellular effects and interactions of the Rho-family GTPase TC10
    • Neudauer CL, Joberty G, Tatsis N, Macara IG, (1998) Distinct cellular effects and interactions of the Rho-family GTPase TC10. Curr Biol 8: 1151-1160
    • (1998) Curr Biol , vol.8 , pp. 1151-1160
    • Neudauer, C.L.1    Joberty, G.2    Tatsis, N.3    Macara, I.G.4
  • 199
    • 84897404602 scopus 로고    scopus 로고
    • IQGAP1 binds to estrogen receptor-alpha and modulates its function
    • Erdemir HH, Li Z, Sacks DB, (2014) IQGAP1 binds to estrogen receptor-alpha and modulates its function. J Biol Chem 289: 9100-9112
    • (2014) J Biol Chem , vol.289 , pp. 9100-9112
    • Erdemir, H.H.1    Li, Z.2    Sacks, D.B.3
  • 200
    • 77954922964 scopus 로고    scopus 로고
    • Activator-Mediator binding regulates Mediator-cofactor interactions
    • Ebmeier CC, Taatjes DJ, (2010) Activator-Mediator binding regulates Mediator-cofactor interactions. Proc Natl Acad Sci U S A 107: 11283-11288
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11283-11288
    • Ebmeier, C.C.1    Taatjes, D.J.2
  • 201
    • 84858986637 scopus 로고    scopus 로고
    • Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation
    • Li J, Chu M, Wang S, Chan D, Qi S, Wu M, Zhou Z, Nishi E, Qin J, Wong J, (2012) Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation. J Biol Chem 287: 10089-10098
    • (2012) J Biol Chem , vol.287 , pp. 10089-10098
    • Li, J.1    Chu, M.2    Wang, S.3    Chan, D.4    Qi, S.5    Wu, M.6    Zhou, Z.7    Nishi, E.8    Qin, J.9    Wong, J.10
  • 203
    • 84881226456 scopus 로고    scopus 로고
    • The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway
    • Cheung KL, Lee JH, Shu L, Kim JH, Sacks DB, Kong AN, (2013) The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway. J Biol Chem 288: 22378-22386
    • (2013) J Biol Chem , vol.288 , pp. 22378-22386
    • Cheung, K.L.1    Lee, J.H.2    Shu, L.3    Kim, J.H.4    Sacks, D.B.5    Kong, A.N.6
  • 204
    • 84879154874 scopus 로고    scopus 로고
    • Identification and functional studies of a new Nrf2 partner IQGAP1: A critical role in the stability and transactivation of Nrf2
    • Kim JH, Xu EY, Sacks DB, Lee J, Shu L, Xia B, Kong AN, (2013) Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2. Antioxid Redox Signal 19: 89-101
    • (2013) Antioxid Redox Signal , vol.19 , pp. 89-101
    • Kim, J.H.1    Xu, E.Y.2    Sacks, D.B.3    Lee, J.4    Shu, L.5    Xia, B.6    Kong, A.N.7
  • 205
    • 78650232705 scopus 로고    scopus 로고
    • IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest
    • Johnson M, Sharma M, Brocardo MG, Henderson BR, (2011) IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest. Int J Biochem Cell Biol 43: 65-73
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 65-73
    • Johnson, M.1    Sharma, M.2    Brocardo, M.G.3    Henderson, B.R.4
  • 207
    • 79952108946 scopus 로고    scopus 로고
    • Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line
    • Sato A, Naito T, Hiramoto A, Goda K, Omi T, Kitade Y, Sasaki T, Matsuda A, Fukushima M, Wataya Y, et al, (2010) Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line. FEBS J 277: 4464-4473
    • (2010) FEBS J , vol.277 , pp. 4464-4473
    • Sato, A.1    Naito, T.2    Hiramoto, A.3    Goda, K.4    Omi, T.5    Kitade, Y.6    Sasaki, T.7    Matsuda, A.8    Fukushima, M.9    Wataya, Y.10
  • 208
    • 80054818729 scopus 로고    scopus 로고
    • Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway
    • Toyokawa G, Cho HS, Masuda K, Yamane Y, Yoshimatsu M, Hayami S, Takawa M, Iwai Y, Daigo Y, Tsuchiya E, et al, (2011) Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway. Neoplasia 13: 887-898
    • (2011) Neoplasia , vol.13 , pp. 887-898
    • Toyokawa, G.1    Cho, H.S.2    Masuda, K.3    Yamane, Y.4    Yoshimatsu, M.5    Hayami, S.6    Takawa, M.7    Iwai, Y.8    Daigo, Y.9    Tsuchiya, E.10
  • 209
    • 84860356248 scopus 로고    scopus 로고
    • Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins
    • Sun L, Prince T, Manjarrez JR, Scroggins BT, Matts RL, (2012) Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochim Biophys Acta 1823: 1092-1101
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1092-1101
    • Sun, L.1    Prince, T.2    Manjarrez, J.R.3    Scroggins, B.T.4    Matts, R.L.5
  • 211
    • 2342487399 scopus 로고    scopus 로고
    • The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs
    • Villace P, Marion RM, Ortin J, (2004) The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs. Nucleic Acids Res 32: 2411-2420
    • (2004) Nucleic Acids Res , vol.32 , pp. 2411-2420
    • Villace, P.1    Marion, R.M.2    Ortin, J.3
  • 212
    • 84908305287 scopus 로고    scopus 로고
    • IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM
    • Chung LK, Philip NH, Schmidt VA, Koller A, Strowig T, Flavell RA, Brodsky IE, Bliska JB, (2014) IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM. MBio 5: e01402-14
    • (2014) MBio , vol.5 , pp. e1402-e1414
    • Chung, L.K.1    Philip, N.H.2    Schmidt, V.A.3    Koller, A.4    Strowig, T.5    Flavell, R.A.6    Brodsky, I.E.7    Bliska, J.B.8
  • 215
    • 39749108409 scopus 로고    scopus 로고
    • Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent
    • Schmidt VA, Chiariello CS, Capilla E, Miller F, Bahou WF, (2008) Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent. Mol Cell Biol 28: 1489-1502
    • (2008) Mol Cell Biol , vol.28 , pp. 1489-1502
    • Schmidt, V.A.1    Chiariello, C.S.2    Capilla, E.3    Miller, F.4    Bahou, W.F.5
  • 217
    • 48649099673 scopus 로고    scopus 로고
    • IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade
    • Nojima H, Adachi M, Matsui T, Okawa K, Tsukita S, (2008) IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade. Nat Cell Biol 10: 971-978
    • (2008) Nat Cell Biol , vol.10 , pp. 971-978
    • Nojima, H.1    Adachi, M.2    Matsui, T.3    Okawa, K.4    Tsukita, S.5
  • 220
    • 76449096124 scopus 로고    scopus 로고
    • Role of host cell polarity and leading edge properties in Pseudomonas type III secretion
    • Bridge DR, Novotny MJ, Moore ER, Olson JC, (2009) Role of host cell polarity and leading edge properties in Pseudomonas type III secretion. Microbiology 156: 356-373
    • (2009) Microbiology , vol.156 , pp. 356-373
    • Bridge, D.R.1    Novotny, M.J.2    Moore, E.R.3    Olson, J.C.4


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