TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia

Genes and Development

Volumn 24, Issue 19, 2010, Pages 2180-2193

  Mukhopadhyay, Saikat ^a   Wen, Xiaohui ^a   Chih, Ben ^a   Nelson, Christopher D ^a   Lane, William S ^b   Scales, Suzie J ^a   Jackson, Peter K ^a  

^a GENENTECH INC   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

G protein coupled receptor; Hedgehog; Intraflagellar transport; Primary cilia; TULP3

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PHOSPHATIDYLINOSITIDE; PROTEIN; SONIC HEDGEHOG PROTEIN; TUBBY LIKE PROTEIN 3; UNCLASSIFIED DRUG; CELL RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; PHOSPHATIDYLINOSITOL; TULP3 PROTEIN, MOUSE;

ARTICLE; CELL MIGRATION; EUKARYOTIC FLAGELLUM; HUMAN; HUMAN CELL; INTRAFLAGELLAR TRANSPORT; MEMBRANE BINDING; NEURAL TUBE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

ERINACEIDAE; MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELLS, CULTURED; CILIA; GTP-BINDING PROTEINS; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE ALIGNMENT;

EID: 77957682469     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1966210     Document Type: Article

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