The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

Nature Immunology

Volumn 12, Issue 11, 2011, Pages 1063-1070

  Liu, Zhihua ^a   Lee, Jinwoo ^a   Krummey, Scott ^a   Lu, Wei ^a   Cai, Huaibin ^b   Lenardo, Michael J ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT KINASE 2; RNA; TRANSCRIPTION FACTOR NFAT;

ALLELE; ARTICLE; COLITIS; CONTROLLED STUDY; CROHN DISEASE; DISEASE SEVERITY; ENTERITIS; ENZYME DEFICIENCY; GENOME; HUMAN; IMMUNOREGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; COLITIS; CROHN DISEASE; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MACROPHAGE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RNA, UNTRANSLATED; TRANSGENES;

EID: 80054933395     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2113     Document Type: Article

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