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Volumn 8, Issue 2, 2013, Pages

β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion via Rap1 and IQGAP1

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 2; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MESSENGER RNA; RAP1 PROTEIN; RAP1A PROTEIN; UNCLASSIFIED DRUG;

EID: 84873539187     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056174     Document Type: Article
Times cited : (58)

References (63)
  • 2
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz RJ, Shenoy SK, (2005) Transduction of receptor signals by beta-arrestins. Science 308: 512-517.
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 3
    • 80052359992 scopus 로고    scopus 로고
    • Emerging paradigms of beta-arrestin-dependent seven transmembrane receptor signaling
    • Shukla XK, Lefkowitz RJ, (2011) Emerging paradigms of beta-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem Sci 36: 457-469.
    • (2011) Trends Biochem Sci , vol.36 , pp. 457-469
    • Shukla, X.K.1    Lefkowitz, R.J.2
  • 4
    • 78650854802 scopus 로고    scopus 로고
    • Beta-arrestins as regulators of signal termination and transduction: how do they determine what to scaffold
    • DeFea KA, (2011) Beta-arrestins as regulators of signal termination and transduction: how do they determine what to scaffold? Cell Signal 23: 621-629.
    • (2011) Cell Signal , vol.23 , pp. 621-629
    • DeFea, K.A.1
  • 5
    • 80054782210 scopus 로고    scopus 로고
    • beta-arrestin-dependent actin reorganization: bringing the right players together at the leading edge
    • Min J, Defea K, (2011) beta-arrestin-dependent actin reorganization: bringing the right players together at the leading edge. Mol Pharmacol 80: 760-768.
    • (2011) Mol Pharmacol , vol.80 , pp. 760-768
    • Min, J.1    Defea, K.2
  • 6
    • 14844338481 scopus 로고    scopus 로고
    • beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
    • Barnes WG, Reiter E, Violin JD, Ren XR, Milligan G, et al. (2005) beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J Biol Chem 280: 8041-8050.
    • (2005) J Biol Chem , vol.280 , pp. 8041-8050
    • Barnes, W.G.1    Reiter, E.2    Violin, J.D.3    Ren, X.R.4    Milligan, G.5
  • 7
    • 0037147145 scopus 로고    scopus 로고
    • Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
    • Sun Y, Cheng Z, Ma L, Pei G, (2002) Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem 277: 49212-49219.
    • (2002) J Biol Chem , vol.277 , pp. 49212-49219
    • Sun, Y.1    Cheng, Z.2    Ma, L.3    Pei, G.4
  • 8
    • 34547107639 scopus 로고    scopus 로고
    • Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
    • Zoudilova M, Kumar P, Ge L, Wang P, Bokoch GM, et al. (2007) Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J Biol Chem 282: 20634-20646.
    • (2007) J Biol Chem , vol.282 , pp. 20634-20646
    • Zoudilova, M.1    Kumar, P.2    Ge, L.3    Wang, P.4    Bokoch, G.M.5
  • 9
    • 64849103757 scopus 로고    scopus 로고
    • G protein-coupled receptors stimulation and the control of cell migration
    • Cotton M, Claing A, (2009) G protein-coupled receptors stimulation and the control of cell migration. Cell Signal 21: 1045-1053.
    • (2009) Cell Signal , vol.21 , pp. 1045-1053
    • Cotton, M.1    Claing, A.2
  • 10
    • 66249141288 scopus 로고    scopus 로고
    • The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42
    • Mythreye K, Blobe GC, (2009) The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42. Proc Natl Acad Sci U S A 106: 8221-8226.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 8221-8226
    • Mythreye, K.1    Blobe, G.C.2
  • 11
    • 34249705229 scopus 로고    scopus 로고
    • Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression
    • Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Vasilcanu D, et al. (2007) Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression. J Biol Chem 282: 11329-11338.
    • (2007) J Biol Chem , vol.282 , pp. 11329-11338
    • Girnita, L.1    Shenoy, S.K.2    Sehat, B.3    Vasilcanu, R.4    Vasilcanu, D.5
  • 12
    • 55249127104 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis
    • Matsubayashi J, Takanashi M, Oikawa K, Fujita K, Tanaka M, et al. (2008) Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis. J Pathol 216: 317-327.
    • (2008) J Pathol , vol.216 , pp. 317-327
    • Matsubayashi, J.1    Takanashi, M.2    Oikawa, K.3    Fujita, K.4    Tanaka, M.5
  • 13
    • 62449145673 scopus 로고    scopus 로고
    • Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
    • Rosano L, Cianfrocca R, Masi S, Spinella F, Di Castro V, et al. (2009) Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci U S A 106: 2806-2811.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2806-2811
    • Rosano, L.1    Cianfrocca, R.2    Masi, S.3    Spinella, F.4    Di Castro, V.5
  • 15
    • 45949097905 scopus 로고    scopus 로고
    • Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer
    • Raghuwanshi SK, Nasser MW, Chen X, Strieter RM, Richardson RM, (2008) Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer. J Immunol 180: 5699-5706.
    • (2008) J Immunol , vol.180 , pp. 5699-5706
    • Raghuwanshi, S.K.1    Nasser, M.W.2    Chen, X.3    Strieter, R.M.4    Richardson, R.M.5
  • 16
    • 38949163338 scopus 로고    scopus 로고
    • Rapid xenograft tumor progression in beta-arrestin1 transgenic mice due to enhanced tumor angiogenesis
    • Zou L, Yang R, Chai J, Pei G, (2008) Rapid xenograft tumor progression in beta-arrestin1 transgenic mice due to enhanced tumor angiogenesis. FASEB J 22: 355-364.
    • (2008) FASEB J , vol.22 , pp. 355-364
    • Zou, L.1    Yang, R.2    Chai, J.3    Pei, G.4
  • 17
    • 33846998992 scopus 로고    scopus 로고
    • Beta-arrestin signaling and regulation of transcription
    • Ma L, Pei G, (2007) Beta-arrestin signaling and regulation of transcription. J Cell Sci 120: 213-218.
    • (2007) J Cell Sci , vol.120 , pp. 213-218
    • Ma, L.1    Pei, G.2
  • 18
    • 67249152481 scopus 로고    scopus 로고
    • Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer
    • Lakshmikanthan V, Zou L, Kim JI, Michal A, Nie Z, et al. (2009) Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer. Proc Natl Acad Sci U S A 106: 9379-9384.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9379-9384
    • Lakshmikanthan, V.1    Zou, L.2    Kim, J.I.3    Michal, A.4    Nie, Z.5
  • 19
    • 84873543386 scopus 로고    scopus 로고
    • beta-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression
    • Shenoy SK, Han S, Zhao YL, Hara MR, Oliver T, et al. (2011) beta-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. Oncogene 22: 256-265.
    • (2011) Oncogene , vol.22 , pp. 256-265
    • Shenoy, S.K.1    Han, S.2    Zhao, Y.L.3    Hara, M.R.4    Oliver, T.5
  • 20
    • 67651151233 scopus 로고    scopus 로고
    • Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells
    • Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, et al. (2009) Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res 7: 1064-1077.
    • (2009) Mol Cancer Res , vol.7 , pp. 1064-1077
    • Li, T.T.1    Alemayehu, M.2    Aziziyeh, A.I.3    Pape, C.4    Pampillo, M.5
  • 21
    • 82255163335 scopus 로고    scopus 로고
    • Differential expression of arrestins is a predictor of breast cancer progression and survival
    • Michal AM, Peck AR, Tran TH, Liu C, Rimm DL, et al. (2011) Differential expression of arrestins is a predictor of breast cancer progression and survival. Breast Cancer Res Treat 130: 791-807.
    • (2011) Breast Cancer Res Treat , vol.130 , pp. 791-807
    • Michal, A.M.1    Peck, A.R.2    Tran, T.H.3    Liu, C.4    Rimm, D.L.5
  • 22
    • 79959610178 scopus 로고    scopus 로고
    • GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness
    • Zajac M, Law J, Cvetkovic DD, Pampillo M, McColl L, et al. (2011) GPR54 (KISS1R) Transactivates EGFR to Promote Breast Cancer Cell Invasiveness. PLoS One 6: e21599.
    • (2011) PLoS One , vol.6
    • Zajac, M.1    Law, J.2    Cvetkovic, D.D.3    Pampillo, M.4    McColl, L.5
  • 23
    • 77952415656 scopus 로고    scopus 로고
    • Beyond desensitization: physiological relevance of arrestin-dependent signaling
    • Luttrell LM, Gesty-Palmer D, (2010) Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev 62: 305-330.
    • (2010) Pharmacol Rev , vol.62 , pp. 305-330
    • Luttrell, L.M.1    Gesty-Palmer, D.2
  • 24
    • 29244461715 scopus 로고    scopus 로고
    • A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors
    • Urs NM, Jones KT, Salo PD, Severin JE, Trejo J, et al. (2005) A requirement for membrane cholesterol in the beta-arrestin- and clathrin-dependent endocytosis of LPA1 lysophosphatidic acid receptors. J Cell Sci 118: 5291-5304.
    • (2005) J Cell Sci , vol.118 , pp. 5291-5304
    • Urs, N.M.1    Jones, K.T.2    Salo, P.D.3    Severin, J.E.4    Trejo, J.5
  • 25
    • 34848814480 scopus 로고    scopus 로고
    • Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing
    • Watterson KR, Lanning DA, Diegelmann RF, Spiegel S, (2007) Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing. Wound Repair Regen 15: 607-616.
    • (2007) Wound Repair Regen , vol.15 , pp. 607-616
    • Watterson, K.R.1    Lanning, D.A.2    Diegelmann, R.F.3    Spiegel, S.4
  • 26
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • Mills GB, Moolenaar WH, (2003) The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer 3: 582-591.
    • (2003) Nat Rev Cancer , vol.3 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 29
    • 65649132676 scopus 로고    scopus 로고
    • Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases
    • Liu S, Umezu-Goto M, Murph M, Lu Y, Liu W, et al. (2009) Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell 15: 539-550.
    • (2009) Cancer Cell , vol.15 , pp. 539-550
    • Liu, S.1    Umezu-Goto, M.2    Murph, M.3    Lu, Y.4    Liu, W.5
  • 30
    • 78651260241 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling
    • Du J, Sun C, Hu Z, Yang Y, Zhu Y, et al. (2010) Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling. PlosOne 5(12): e15940.
    • (2010) PlosOne , vol.5 , Issue.12
    • Du, J.1    Sun, C.2    Hu, Z.3    Yang, Y.4    Zhu, Y.5
  • 31
    • 34250630498 scopus 로고    scopus 로고
    • LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells
    • Chen M, Towers LN, O'Connor KL, (2007) LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells. Am J Physiol Cell Physiol 292: C1927-1933.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Chen, M.1    Towers, L.N.2    O'Connor, K.L.3
  • 32
    • 18544379729 scopus 로고    scopus 로고
    • Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization
    • Bhattacharya M, Anborgh PH, Babwah AV, Dale LB, Dobransky T, et al. (2002) Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization. Nat Cell Biol 4: 547-555.
    • (2002) Nat Cell Biol , vol.4 , pp. 547-555
    • Bhattacharya, M.1    Anborgh, P.H.2    Babwah, A.V.3    Dale, L.B.4    Dobransky, T.5
  • 33
    • 0029913467 scopus 로고    scopus 로고
    • Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
    • Herrmann C, Horn G, Spaargaren M, Wittinghofer A, (1996) Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. J Biol Chem 271: 6794-6800.
    • (1996) J Biol Chem , vol.271 , pp. 6794-6800
    • Herrmann, C.1    Horn, G.2    Spaargaren, M.3    Wittinghofer, A.4
  • 34
    • 77649191184 scopus 로고    scopus 로고
    • Rap1, a mercenary among the Ras-like GTPases
    • Frische EW, Zwartkruis FJ, (2010) Rap1, a mercenary among the Ras-like GTPases. Dev Biol 340(1): 1-9.
    • (2010) Dev Biol , vol.340 , Issue.1 , pp. 1-9
    • Frische, E.W.1    Zwartkruis, F.J.2
  • 35
    • 74949088546 scopus 로고    scopus 로고
    • Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck
    • Goto M, Mitra RS, Liu M, Lee J, Henson BS, et al. (2010) Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck. Clin Cancer Res 16: 65-76.
    • (2010) Clin Cancer Res , vol.16 , pp. 65-76
    • Goto, M.1    Mitra, R.S.2    Liu, M.3    Lee, J.4    Henson, B.S.5
  • 36
    • 0142024483 scopus 로고    scopus 로고
    • Rap1 GTPase: functions, regulation, and malignancy
    • Hattori M, Minato N, (2003) Rap1 GTPase: functions, regulation, and malignancy. J Biochem 134: 479-484.
    • (2003) J Biochem , vol.134 , pp. 479-484
    • Hattori, M.1    Minato, N.2
  • 37
    • 80052645527 scopus 로고    scopus 로고
    • Ras-related protein 1 and the insulin-like growth factor type I receptor are associated with risk of progression in patients diagnosed with carcinoma in situ
    • Furstenau DK, Mitra N, Wan F, Lewis R, Feldman MD, et al. (2011) Ras-related protein 1 and the insulin-like growth factor type I receptor are associated with risk of progression in patients diagnosed with carcinoma in situ. Breast Cancer Res Treat 129(2): 361-372.
    • (2011) Breast Cancer Res Treat , vol.129 , Issue.2 , pp. 361-372
    • Furstenau, D.K.1    Mitra, N.2    Wan, F.3    Lewis, R.4    Feldman, M.D.5
  • 38
    • 34250304220 scopus 로고    scopus 로고
    • Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells
    • Itoh M, Nelson CM, Myers CA, Bissell MJ, (2007) Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells. Cancer Res 67: 4759-4766.
    • (2007) Cancer Res , vol.67 , pp. 4759-4766
    • Itoh, M.1    Nelson, C.M.2    Myers, C.A.3    Bissell, M.J.4
  • 39
    • 33646726750 scopus 로고    scopus 로고
    • IQGAP1 in cellular signaling: bridging the GAP
    • Brown MD, Sacks DB, (2006) IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol 16: 242-249.
    • (2006) Trends Cell Biol , vol.16 , pp. 242-249
    • Brown, M.D.1    Sacks, D.B.2
  • 42
    • 78651260241 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling
    • Du J, Sun C, Hu Z, Yang Y, Zhu Y, et al. (2010) Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling. PLoS One 5: e15940.
    • (2010) PLoS One , vol.5
    • Du, J.1    Sun, C.2    Hu, Z.3    Yang, Y.4    Zhu, Y.5
  • 43
    • 10744225477 scopus 로고    scopus 로고
    • Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells
    • Fang X, Yu S, Bast RC, Liu S, Xu HJ, et al. (2004) Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells. J Biol Chem 279: 9653-9661.
    • (2004) J Biol Chem , vol.279 , pp. 9653-9661
    • Fang, X.1    Yu, S.2    Bast, R.C.3    Liu, S.4    Xu, H.J.5
  • 44
    • 17044448378 scopus 로고    scopus 로고
    • Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK
    • Stahle M, Veit C, Bachfischer U, Schierling K, Skripczynski B, et al. (2003) Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J Cell Sci 116: 3835-3846.
    • (2003) J Cell Sci , vol.116 , pp. 3835-3846
    • Stahle, M.1    Veit, C.2    Bachfischer, U.3    Schierling, K.4    Skripczynski, B.5
  • 45
    • 0032531756 scopus 로고    scopus 로고
    • Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling
    • Zwartkruis FJ, Wolthuis RM, Nabben NM, Franke B, Bos JL, (1998) Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling. EMBO J 17: 5905-5912.
    • (1998) EMBO J , vol.17 , pp. 5905-5912
    • Zwartkruis, F.J.1    Wolthuis, R.M.2    Nabben, N.M.3    Franke, B.4    Bos, J.L.5
  • 46
    • 80052885398 scopus 로고    scopus 로고
    • p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1
    • Kimura T, Mogi C, Sato K, Tomura H, Ohta H, et al. (2011) p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1. Cardiovasc Res 92: 149-158.
    • (2011) Cardiovasc Res , vol.92 , pp. 149-158
    • Kimura, T.1    Mogi, C.2    Sato, K.3    Tomura, H.4    Ohta, H.5
  • 47
    • 34547103558 scopus 로고    scopus 로고
    • IQGAP1 binds Rap1 and modulates its activity
    • Jeong HW, Li Z, Brown MD, Sacks DB, (2007) IQGAP1 binds Rap1 and modulates its activity. J Biol Chem 282: 20752-20762.
    • (2007) J Biol Chem , vol.282 , pp. 20752-20762
    • Jeong, H.W.1    Li, Z.2    Brown, M.D.3    Sacks, D.B.4
  • 48
    • 18444369936 scopus 로고    scopus 로고
    • Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
    • Fukata M, Watanabe T, Noritake J, Nakagawa M, Yamaga M, et al. (2002) Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell 109: 873-885.
    • (2002) Cell , vol.109 , pp. 873-885
    • Fukata, M.1    Watanabe, T.2    Noritake, J.3    Nakagawa, M.4    Yamaga, M.5
  • 49
    • 38149036613 scopus 로고    scopus 로고
    • IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
    • Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB, (2008) IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem 283: 1008-1017.
    • (2008) J Biol Chem , vol.283 , pp. 1008-1017
    • Jadeski, L.1    Mataraza, J.M.2    Jeong, H.W.3    Li, Z.4    Sacks, D.B.5
  • 50
    • 79959677602 scopus 로고    scopus 로고
    • Life at the leading edge
    • Ridley AJ, (2011) Life at the leading edge. Cell 145: 1012-1022.
    • (2011) Cell , vol.145 , pp. 1012-1022
    • Ridley, A.J.1
  • 51
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • Bos JL, (2005) Linking Rap to cell adhesion. Curr Opin Cell Biol 17: 123-128.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 123-128
    • Bos, J.L.1
  • 52
    • 34547512353 scopus 로고    scopus 로고
    • Functional specialization of beta-arrestin interactions revealed by proteomic analysis
    • Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, et al. (2007) Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proc Natl Acad Sci U S A 104: 12011-12016.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12011-12016
    • Xiao, K.1    McClatchy, D.B.2    Shukla, A.K.3    Zhao, Y.4    Chen, M.5
  • 53
    • 84873565464 scopus 로고    scopus 로고
    • IQGAP1 and its binding proteins control diverse biological functions
    • White CD, Erdemir HH, Sacks DB (2011) IQGAP1 and its binding proteins control diverse biological functions. Cell Signalling.
    • (2011) Cell Signalling
    • White, C.D.1    Erdemir, H.H.2    Sacks, D.B.3
  • 54
    • 33947607229 scopus 로고    scopus 로고
    • Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity
    • Hanson SM, Cleghorn WM, Francis DJ, Vishnivetskiy SA, Raman D, et al. (2007) Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity. J Mol Biol 368: 375-387.
    • (2007) J Mol Biol , vol.368 , pp. 375-387
    • Hanson, S.M.1    Cleghorn, W.M.2    Francis, D.J.3    Vishnivetskiy, S.A.4    Raman, D.5
  • 55
    • 79955770162 scopus 로고    scopus 로고
    • Scaffold proteins: hubs for controlling the flow of cellular information
    • Good MC, Zalatan JG, Lim WA, (2011) Scaffold proteins: hubs for controlling the flow of cellular information. Science 332: 680-686.
    • (2011) Science , vol.332 , pp. 680-686
    • Good, M.C.1    Zalatan, J.G.2    Lim, W.A.3
  • 56
    • 79952111834 scopus 로고    scopus 로고
    • Organizing signal transduction through A-kinase anchoring proteins (AKAPs)
    • Logue JS, Scott JD, (2010) Organizing signal transduction through A-kinase anchoring proteins (AKAPs). FEBS J 21: 4370-4375.
    • (2010) FEBS J , vol.21 , pp. 4370-4375
    • Logue, J.S.1    Scott, J.D.2
  • 57
    • 45349084318 scopus 로고    scopus 로고
    • The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
    • Sakurai-Yageta M, Recchi C, Le Dez G, Sibarita JB, Daviet L, et al. (2008) The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol 181: 985-998.
    • (2008) J Cell Biol , vol.181 , pp. 985-998
    • Sakurai-Yageta, M.1    Recchi, C.2    Le Dez, G.3    Sibarita, J.B.4    Daviet, L.5
  • 58
    • 64049090068 scopus 로고    scopus 로고
    • Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS
    • Li J, Ghio AJ, Cho SH, Brinckerhoff CE, Simon SA, et al. (2009) Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS. Environ Health Perspect 117: 400-409.
    • (2009) Environ Health Perspect , vol.117 , pp. 400-409
    • Li, J.1    Ghio, A.J.2    Cho, S.H.3    Brinckerhoff, C.E.4    Simon, S.A.5
  • 59
    • 67449124367 scopus 로고    scopus 로고
    • Activation of Rap1 promotes prostate cancer metastasis
    • Bailey CL, Kelly P, Casey PJ, (2009) Activation of Rap1 promotes prostate cancer metastasis. Cancer Res 69: 4962-4968.
    • (2009) Cancer Res , vol.69 , pp. 4962-4968
    • Bailey, C.L.1    Kelly, P.2    Casey, P.J.3
  • 60
    • 45549107951 scopus 로고    scopus 로고
    • Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma
    • Mitra RS, Goto M, Lee JS, Maldonado D, Taylor JM, et al. (2008) Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma. Cancer Res 68: 3959-3969.
    • (2008) Cancer Res , vol.68 , pp. 3959-3969
    • Mitra, R.S.1    Goto, M.2    Lee, J.S.3    Maldonado, D.4    Taylor, J.M.5
  • 62
    • 84860389407 scopus 로고    scopus 로고
    • Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase
    • McSherry EF, Brannan K, Hudson L, Hill AD, Hopkins AM, (2011) Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase. Breast Cancer Res 13: R31.
    • (2011) Breast Cancer Res , vol.13
    • McSherry, E.F.1    Brannan, K.2    Hudson, L.3    Hill, A.D.4    Hopkins, A.M.5
  • 63
    • 34948857003 scopus 로고    scopus 로고
    • AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB-231 breast cancer cells
    • Dorfleutner A, Stehlik C, Zhang J, Gallick GE, Flynn DC, (2007) AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB-231 breast cancer cells. J Cell Physiol 213: 740-749.
    • (2007) J Cell Physiol , vol.213 , pp. 740-749
    • Dorfleutner, A.1    Stehlik, C.2    Zhang, J.3    Gallick, G.E.4    Flynn, D.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.