Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-Cadherin-mediated cell-cell adhesion

Science

Volumn 281, Issue 5378, 1998, Pages 832-835

  Kuroda, Shinya ^a   Fukata, Masaki ^a   Nakagawa, Masato ^a   Fujii, Katsuhiko ^a   Nakamura, Tomoko ^a   Ookubo, Tadashi ^a   Izawa, Ichiro ^a   Nagase, Takahiro ^a   Nomura, Nobuo ^a   Tani, Hideki ^a   Shoji, Ikuo ^a   Matsuura, Yoshiharu ^a   Yonehara, Shin ^a   Kaibuchi, Kozo ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CELL PROTEIN; GUANOSINE TRIPHOSPHATASE; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GENE OVEREXPRESSION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ALPHA CATENIN; ANIMALS; BETA CATENIN; CADHERINS; CDC42 GTP-BINDING PROTEIN; CELL ADHESION; CELL CYCLE PROTEINS; CELL MEMBRANE; CYTOSKELETAL PROTEINS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; L CELLS (CELL LINE); MICE; MUTATION; PROTEINS; RAC GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0032493903     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.281.5378.832     Document Type: Article

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40. We thank A. Nagafuchi and S. Tsukita for providing L, EL, and nEαCL cells; cDNAs encoding E-cadherin, α-catenin, or β-catenin; and antibodies to E-cadherin (ECCD-2) or to α-catenin. We also thank M. Takeichi for providing ECCD-2 and Kazusa DNA Research Institute for support of a cDNA Research Program. Supported by grants-in-aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan (1997), by the Japan Society for the Promotion of Science Research for the Future, by the Human Frontier Science Program, and by grants from Kirin Brewery Co. Ltd.