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Volumn 8, Issue 4, 2013, Pages

IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling

Author keywords

[No Author keywords available]

Indexed keywords

DISHEVELLED 1; DISHEVELLED 2; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; WNT PROTEIN;

EID: 84875930807     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060865     Document Type: Article
Times cited : (26)

References (52)
  • 1
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R, (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 2
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H, (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 3
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus
    • Peifer M, Polakis P, (2000) Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science 287: 1606-1609.
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 4
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz A, Nusse R, (1998) Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol 14: 59-88.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 5
    • 0034644526 scopus 로고    scopus 로고
    • Linking colorectal cancer to Wnt signaling
    • Bienz M, Clevers H, (2000) Linking colorectal cancer to Wnt signaling. Cell 103: 311-320.
    • (2000) Cell , vol.103 , pp. 311-320
    • Bienz, M.1    Clevers, H.2
  • 6
    • 0030739838 scopus 로고    scopus 로고
    • Carcinogenesis: a balance between beta-catenin and APC
    • Gumbiner BM, (1997) Carcinogenesis: a balance between beta-catenin and APC. Curr Biol 7: R443-R446.
    • (1997) Curr Biol , vol.7
    • Gumbiner, B.M.1
  • 7
    • 0030861128 scopus 로고    scopus 로고
    • Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus
    • Miller JR, Moon RT, (1997) Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus. J Cell Biol 139: 229-243.
    • (1997) J Cell Biol , vol.139 , pp. 229-243
    • Miller, J.R.1    Moon, R.T.2
  • 8
    • 0026039487 scopus 로고
    • Injected Wnt RNA induces a complete body axis in Xenopus embryos
    • Sokol S, Christian JL, Moon RT, Melton DA, (1991) Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell 67: 741-752.
    • (1991) Cell , vol.67 , pp. 741-752
    • Sokol, S.1    Christian, J.L.2    Moon, R.T.3    Melton, D.A.4
  • 9
    • 0028954815 scopus 로고
    • Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling
    • Funayama N, Fagotto F, McCrea P, Gumbiner BM, (1995) Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling. J Cell Biol 128: 959-968.
    • (1995) J Cell Biol , vol.128 , pp. 959-968
    • Funayama, N.1    Fagotto, F.2    McCrea, P.3    Gumbiner, B.M.4
  • 10
    • 0029915306 scopus 로고    scopus 로고
    • Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus
    • Fagotto F, Funayama N, Gluck U, Gumbiner BM, (1996) Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus. J Cell Biol 132: 1105-1114.
    • (1996) J Cell Biol , vol.132 , pp. 1105-1114
    • Fagotto, F.1    Funayama, N.2    Gluck, U.3    Gumbiner, B.M.4
  • 11
    • 0030293782 scopus 로고    scopus 로고
    • Analysis of Dishevelled signalling pathways during Xenopus development
    • Sokol SY, (1996) Analysis of Dishevelled signalling pathways during Xenopus development. Curr Biol 6: 1456-1467.
    • (1996) Curr Biol , vol.6 , pp. 1456-1467
    • Sokol, S.Y.1
  • 12
    • 0029832381 scopus 로고    scopus 로고
    • The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm
    • Carnac G, Kodjabachian L, Gurdon JB, Lemaire P, (1996) The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm. Development 122: 3055-3065.
    • (1996) Development , vol.122 , pp. 3055-3065
    • Carnac, G.1    Kodjabachian, L.2    Gurdon, J.B.3    Lemaire, P.4
  • 13
    • 0030471628 scopus 로고    scopus 로고
    • Combinatorial signalling by Xwnt-11 and Xnr3 in the organizer epithelium
    • Glinka A, Delius H, Blumenstock C, Niehrs C, (1996) Combinatorial signalling by Xwnt-11 and Xnr3 in the organizer epithelium. Mech Dev 60: 221-231.
    • (1996) Mech Dev , vol.60 , pp. 221-231
    • Glinka, A.1    Delius, H.2    Blumenstock, C.3    Niehrs, C.4
  • 14
    • 0031453354 scopus 로고    scopus 로고
    • The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer
    • Laurent MN, Blitz IL, Hashimoto C, Rothbächer U, Cho KW, (1997) The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer. Development 124: 4905-4916.
    • (1997) Development , vol.124 , pp. 4905-4916
    • Laurent, M.N.1    Blitz, I.L.2    Hashimoto, C.3    Rothbächer, U.4    Cho, K.W.5
  • 15
    • 0030219387 scopus 로고    scopus 로고
    • Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2
    • Klingensmith J, Yang Y, Axelrod JD, Beier DR, Perrimon N, et al. (1996) Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mech Dev 58: 15-26.
    • (1996) Mech Dev , vol.58 , pp. 15-26
    • Klingensmith, J.1    Yang, Y.2    Axelrod, J.D.3    Beier, D.R.4    Perrimon, N.5
  • 16
    • 8944229701 scopus 로고    scopus 로고
    • cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene
    • Pizzuti A, Amati F, Calabrese G, Mari A, Colosimo A, et al. (1996) cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene. Hum Mol Genet 5: 953-358.
    • (1996) Hum Mol Genet , vol.5 , pp. 358-953
    • Pizzuti, A.1    Amati, F.2    Calabrese, G.3    Mari, A.4    Colosimo, A.5
  • 17
    • 37549056198 scopus 로고    scopus 로고
    • Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3
    • Lee YN, Gao Y, Wang HY, (2008) Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1,-2, and-3. Cell Signal 20: 443-452.
    • (2008) Cell Signal , vol.20 , pp. 443-452
    • Lee, Y.N.1    Gao, Y.2    Wang, H.Y.3
  • 18
    • 0037126331 scopus 로고    scopus 로고
    • The DIX domain targets dishevelled to actin stress fibres and vesicular membranes
    • Capelluto DG, Kutateladze TG, Habas R, Finkielstein CV, He X, et al. (2002) The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature 419: 726-729.
    • (2002) Nature , vol.419 , pp. 726-729
    • Capelluto, D.G.1    Kutateladze, T.G.2    Habas, R.3    Finkielstein, C.V.4    He, X.5
  • 19
    • 16644386504 scopus 로고    scopus 로고
    • Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1
    • Pan WJ, Pang SZ, Huang T, Guo HY, Wu D, et al. (2004) Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1. Cell Res 14: 324-330.
    • (2004) Cell Res , vol.14 , pp. 324-330
    • Pan, W.J.1    Pang, S.Z.2    Huang, T.3    Guo, H.Y.4    Wu, D.5
  • 20
    • 0032695975 scopus 로고    scopus 로고
    • Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates
    • Moriguchi T, Kawachi K, Kamakura S, Masuyama N, Yamanaka H, et al. (1999) Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates. J Biol Chem 274: 30957-30962.
    • (1999) J Biol Chem , vol.274 , pp. 30957-30962
    • Moriguchi, T.1    Kawachi, K.2    Kamakura, S.3    Masuyama, N.4    Yamanaka, H.5
  • 21
    • 0242690871 scopus 로고    scopus 로고
    • Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis
    • Rothbächer U, Laurent MN, Deardorff MA, Klein PS, Cho KW, et al. (2000) Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis. EMBO J 19: 1010-1022.
    • (2000) EMBO J , vol.19 , pp. 1010-1022
    • Rothbächer, U.1    Laurent, M.N.2    Deardorff, M.A.3    Klein, P.S.4    Cho, K.W.5
  • 22
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N, (1998) Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev 12: 2610-2622.
    • (1998) Genes Dev , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 23
    • 0032504052 scopus 로고    scopus 로고
    • Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    • Boutros M, Paricio N, Strutt DI, Mlodzik M, (1998) Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94: 109-118.
    • (1998) Cell , vol.94 , pp. 109-118
    • Boutros, M.1    Paricio, N.2    Strutt, D.I.3    Mlodzik, M.4
  • 24
    • 41549133557 scopus 로고    scopus 로고
    • Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction
    • Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, et al. (2008) Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J Cell Biol 180: 1087-1100.
    • (2008) J Cell Biol , vol.180 , pp. 1087-1100
    • Gan, X.Q.1    Wang, J.Y.2    Xi, Y.3    Wu, Z.L.4    Li, Y.P.5
  • 25
    • 0029813867 scopus 로고    scopus 로고
    • Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1
    • Kuroda S, Fukata M, Kobayashi K, Nakafuku M, Nomura N, et al. (1996) Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1. J Biol Chem 271: 23363-23367.
    • (1996) J Biol Chem , vol.271 , pp. 23363-23367
    • Kuroda, S.1    Fukata, M.2    Kobayashi, K.3    Nakafuku, M.4    Nomura, N.5
  • 26
    • 0030943857 scopus 로고    scopus 로고
    • Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry
    • Joyal JL, Annan RS, Ho YD, Huddleston ME, Carr SA, et al. (1997) Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry. J Biol Chem 272: 15419-15425.
    • (1997) J Biol Chem , vol.272 , pp. 15419-15425
    • Joyal, J.L.1    Annan, R.S.2    Ho, Y.D.3    Huddleston, M.E.4    Carr, S.A.5
  • 27
    • 0030859462 scopus 로고    scopus 로고
    • Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase
    • Erickson JW, Cerione RA, Hart MJ, (1997) Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase. J Biol Chem 272: 24443-24447.
    • (1997) J Biol Chem , vol.272 , pp. 24443-24447
    • Erickson, J.W.1    Cerione, R.A.2    Hart, M.J.3
  • 28
    • 0032500751 scopus 로고    scopus 로고
    • Binding of myosin essential light chain to the cytoskeleton-associated protein IQGAP1
    • Weissbach L, Bernards A, Herion DW, (1998) Binding of myosin essential light chain to the cytoskeleton-associated protein IQGAP1. Biochem Biophys Res Commun 251: 269-276.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 269-276
    • Weissbach, L.1    Bernards, A.2    Herion, D.W.3
  • 29
    • 0037023772 scopus 로고    scopus 로고
    • The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin
    • Mateer SC, McDaniel AE, Nicolas V, Habermacher GM, Lin MJ, et al. (2002) The mechanism for regulation of the F-actin binding activity of IQGAP1 by calcium/calmodulin. J Biol Chem 277: 12324-12333.
    • (2002) J Biol Chem , vol.277 , pp. 12324-12333
    • Mateer, S.C.1    McDaniel, A.E.2    Nicolas, V.3    Habermacher, G.M.4    Lin, M.J.5
  • 30
    • 0037423218 scopus 로고    scopus 로고
    • Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1
    • Li Z, Sacks DB, (2003) Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1. J Biol Chem 278: 4347-4352.
    • (2003) J Biol Chem , vol.278 , pp. 4347-4352
    • Li, Z.1    Sacks, D.B.2
  • 31
    • 2342424547 scopus 로고    scopus 로고
    • IQGAP1 binds ERK2 and modulates its activity
    • Roy M, Li Z, Sacks DB, (2004) IQGAP1 binds ERK2 and modulates its activity. J Biol Chem 279: 17329-17337.
    • (2004) J Biol Chem , vol.279 , pp. 17329-17337
    • Roy, M.1    Li, Z.2    Sacks, D.B.3
  • 32
    • 1842790679 scopus 로고    scopus 로고
    • Calcium negatively modulates calmodulin interaction with IQGAP1
    • Li Q, Stuenkel EL, (2004) Calcium negatively modulates calmodulin interaction with IQGAP1. Biochem Biophys Res Commun 317: 787-795.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 787-795
    • Li, Q.1    Stuenkel, E.L.2
  • 33
    • 0032493903 scopus 로고    scopus 로고
    • Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion
    • Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, et al. (1998) Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science 281: 832-835.
    • (1998) Science , vol.281 , pp. 832-835
    • Kuroda, S.1    Fukata, M.2    Nakagawa, M.3    Fujii, K.4    Nakamura, T.5
  • 34
    • 0036510761 scopus 로고    scopus 로고
    • IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin
    • Briggs MW, Li Z, Sacks DB, (2002) IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin. J Biol Chem 277: 7453-7465.
    • (2002) J Biol Chem , vol.277 , pp. 7453-7465
    • Briggs, M.W.1    Li, Z.2    Sacks, D.B.3
  • 35
    • 33646726750 scopus 로고    scopus 로고
    • IQGAP1 in cellular signaling: bridging the GAP
    • Brown MD, Sacks DB, (2006) IQGAP1 in cellular signaling: bridging the GAP. Trends Cell Biol 16: 242-249.
    • (2006) Trends Cell Biol , vol.16 , pp. 242-249
    • Brown, M.D.1    Sacks, D.B.2
  • 36
    • 67349198476 scopus 로고    scopus 로고
    • IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis
    • White CD, Brown MD, Sacks DB, (2009) IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis. FEBS Lett 583: 1817-1824.
    • (2009) FEBS Lett , vol.583 , pp. 1817-1824
    • White, C.D.1    Brown, M.D.2    Sacks, D.B.3
  • 37
    • 39749108409 scopus 로고    scopus 로고
    • Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent
    • Schmidt VA, Chiariello CS, Capilla E, Miller F, Bahou WF, (2008) Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent. Mol Cell Biol 28: 1489-1502.
    • (2008) Mol Cell Biol , vol.28 , pp. 1489-1502
    • Schmidt, V.A.1    Chiariello, C.S.2    Capilla, E.3    Miller, F.4    Bahou, W.F.5
  • 38
    • 0037406806 scopus 로고    scopus 로고
    • Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis
    • Yamashiro S, Noguchi T, Mabuchi I, (2003) Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis. Cell Motil Cytoskeleton 55: 36-50.
    • (2003) Cell Motil Cytoskeleton , vol.55 , pp. 36-50
    • Yamashiro, S.1    Noguchi, T.2    Mabuchi, I.3
  • 39
    • 34547673530 scopus 로고    scopus 로고
    • IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos
    • Yamashiro S, Abe H, Mabuchi I, (2007) IQGAP2 is required for the cadherin-mediated cell-to-cell adhesion in Xenopus laevis embryos. Dev Biol 308: 485-493.
    • (2007) Dev Biol , vol.308 , pp. 485-493
    • Yamashiro, S.1    Abe, H.2    Mabuchi, I.3
  • 40
    • 33846990139 scopus 로고    scopus 로고
    • Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling
    • Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY, (2005) Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. J Biol 4: 3.
    • (2005) J Biol , vol.4 , pp. 3
    • Itoh, K.1    Brott, B.K.2    Bae, G.U.3    Ratcliffe, M.J.4    Sokol, S.Y.5
  • 41
    • 0033536001 scopus 로고    scopus 로고
    • A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation
    • Shimizu K, Gurdons JB, (1999) A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation. Proc Natl Acad Sci U S A 96: 6791-6796.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6791-6796
    • Shimizu, K.1    Gurdons, J.B.2
  • 42
    • 75149176441 scopus 로고    scopus 로고
    • Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase
    • Ohnishi E, Goto T, Sato A, Kim MS, Iemura S, et al. (2010) Nemo-like kinase, an essential effector of anterior formation, functions downstream of p38 mitogen-activated protein kinase. Mol Cell Biol 30: 675-683.
    • (2010) Mol Cell Biol , vol.30 , pp. 675-683
    • Ohnishi, E.1    Goto, T.2    Sato, A.3    Kim, M.S.4    Iemura, S.5
  • 43
    • 84873883019 scopus 로고    scopus 로고
    • WNK Signaling Is Involved in Neural Development via Lhx8/Awh Expression
    • Sato A, Shibuya H, (2013) WNK Signaling Is Involved in Neural Development via Lhx8/Awh Expression. PLoS One 8: e55301.
    • (2013) PLoS One , vol.8
    • Sato, A.1    Shibuya, H.2
  • 44
    • 0037106283 scopus 로고    scopus 로고
    • A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics
    • Natsume T, Yamauchi Y, Nakayama H, Shinkawa T, Yanagida M, et al. (2002) A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Anal Chem 74: 4725-4733.
    • (2002) Anal Chem , vol.74 , pp. 4725-4733
    • Natsume, T.1    Yamauchi, Y.2    Nakayama, H.3    Shinkawa, T.4    Yanagida, M.5
  • 45
    • 33846235822 scopus 로고    scopus 로고
    • Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
    • Bryja V, Schulte G, Arenas E, (2007) Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal 19: 610-616.
    • (2007) Cell Signal , vol.19 , pp. 610-616
    • Bryja, V.1    Schulte, G.2    Arenas, E.3
  • 46
    • 0034604726 scopus 로고    scopus 로고
    • Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells
    • Song DH, Sussman DJ, Seldin DC, (2000) Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. J Biol Chem 275: 23790-23797.
    • (2000) J Biol Chem , vol.275 , pp. 23790-23797
    • Song, D.H.1    Sussman, D.J.2    Seldin, D.C.3
  • 47
    • 0037767761 scopus 로고    scopus 로고
    • Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning
    • Bastock R, Strutt H, Strutt D, (2003) Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning. Development 130: 3007-3014.
    • (2003) Development , vol.130 , pp. 3007-3014
    • Bastock, R.1    Strutt, H.2    Strutt, D.3
  • 48
    • 0034943604 scopus 로고    scopus 로고
    • PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
    • Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, et al. (2001) PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling. Nat Cell Biol 3: 628-636.
    • (2001) Nat Cell Biol , vol.3 , pp. 628-636
    • Sun, T.Q.1    Lu, B.2    Feng, J.J.3    Reinhard, C.4    Jan, Y.N.5
  • 49
    • 34547750005 scopus 로고    scopus 로고
    • Dynamic recruitment of axin by Dishevelled protein assemblies
    • Schwarz-Romond T, Metcalfe C, Bienz M, (2007) Dynamic recruitment of axin by Dishevelled protein assemblies. J Cell Sci 120: 2402-2412.
    • (2007) J Cell Sci , vol.120 , pp. 2402-2412
    • Schwarz-Romond, T.1    Metcalfe, C.2    Bienz, M.3
  • 50
    • 0034723073 scopus 로고    scopus 로고
    • Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription
    • Strovel ET, Wu D, Sussman DJ, (2000) Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription. J Biol Chem 275: 2399-2403.
    • (2000) J Biol Chem , vol.275 , pp. 2399-2403
    • Strovel, E.T.1    Wu, D.2    Sussman, D.J.3
  • 51
    • 0036931633 scopus 로고    scopus 로고
    • Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure
    • Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, et al. (2002) Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development 129: 5827-5838.
    • (2002) Development , vol.129 , pp. 5827-5838
    • Hamblet, N.S.1    Lijam, N.2    Ruiz-Lozano, P.3    Wang, J.4    Yang, Y.5
  • 52
    • 57149114315 scopus 로고    scopus 로고
    • Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development
    • Etheridge SL, Ray S, Li S, Hamblet NS, Lijam N, et al. (2008) Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development. PLoS Genet 4: e1000259.
    • (2008) PLoS Genet , vol.4
    • Etheridge, S.L.1    Ray, S.2    Li, S.3    Hamblet, N.S.4    Lijam, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.