메뉴 건너뛰기




Volumn 111, Issue 11, 2014, Pages 4191-4196

G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 161; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84896528786     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320239111     Document Type: Article
Times cited : (63)

References (31)
  • 1
    • 0032875356 scopus 로고    scopus 로고
    • Physiological regulation of G protein-linked signaling
    • Morris AJ, Malbon CC (1999) Physiological regulation of G protein-linked signaling. Physiol Rev 79(4):1373-1430. (Pubitemid 29473319)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1373-1430
    • Morris, A.J.1    Malbon, C.C.2
  • 2
    • 84884594350 scopus 로고    scopus 로고
    • Harnessing the genome for characterization of g-protein coupled receptors in cancer pathogenesis
    • Feigin ME (2013) Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis. FEBS J 280(19):4729-4738.
    • (2013) FEBS J , vol.280 , Issue.19 , pp. 4729-4738
    • Feigin, M.E.1
  • 3
    • 78650845707 scopus 로고    scopus 로고
    • G protein-coupled receptors: Novel targets for drug discovery in cancer
    • Lappano R, Maggiolini M (2011) G protein-coupled receptors: Novel targets for drug discovery in cancer. Nat Rev Drug Discov 10(1):47-60.
    • (2011) Nat Rev Drug Discov , vol.10 , Issue.1 , pp. 47-60
    • Lappano, R.1    Maggiolini, M.2
  • 4
    • 33846474121 scopus 로고    scopus 로고
    • G-protein-coupled receptors and cancer
    • DOI 10.1038/nrc2069, PII NRC2069
    • Dorsam RT, Gutkind JS (2007) G-protein-coupled receptors and cancer. Nat Rev Cancer 7(2):79-94. (Pubitemid 46164746)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.2 , pp. 79-94
    • Dorsam, R.T.1    Gutkind, J.S.2
  • 5
    • 84878219891 scopus 로고    scopus 로고
    • The emerging mutational landscape of g proteins and g-protein-coupled receptors in cancer
    • O'Hayre M, et al. (2013) The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer. Nat Rev Cancer 13(6):412-424.
    • (2013) Nat Rev Cancer , vol.13 , Issue.6 , pp. 412-424
    • O'Hayre, M.1
  • 6
    • 80054997116 scopus 로고    scopus 로고
    • Exon capture analysis of g protein-coupled receptors identifies activating mutations in grm3 in melanoma
    • Prickett TD, et al. (2011) Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet 43(11):1119-1126.
    • (2011) Nat Genet , vol.43 , Issue.11 , pp. 1119-1126
    • Prickett, T.D.1
  • 7
    • 77955660663 scopus 로고    scopus 로고
    • Diverse somatic mutation patterns and pathway alterations in human cancers
    • Kan Z, et al. (2010) Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466(7308):869-873.
    • (2010) Nature , vol.466 , Issue.7308 , pp. 869-873
    • Kan, Z.1
  • 8
    • 84868320535 scopus 로고    scopus 로고
    • Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
    • Liang H, et al. (2012) Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res 22(11):2120-2129.
    • (2012) Genome Res , vol.22 , Issue.11 , pp. 2120-2129
    • Liang, H.1
  • 9
    • 78649329196 scopus 로고    scopus 로고
    • Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing
    • Zhao Q, et al. (2010) Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing. Genome Biol 11(11):R114.
    • (2010) Genome Biol , vol.11 , Issue.11
    • Zhao, Q.1
  • 10
    • 84866894408 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of squamous cell lung cancers
    • Cancer Genome Atlas Research Network
    • Hammerman PS, et al.; Cancer Genome Atlas Research Network (2012) Comprehensive genomic characterization of squamous cell lung cancers. Nature 489(7417): 519-525.
    • (2012) Nature , vol.489 , Issue.7417 , pp. 519-525
    • Hammerman, P.S.1
  • 12
    • 84875993448 scopus 로고    scopus 로고
    • Genetic susceptibility to triple-negative breast cancer
    • Stevens KN, Vachon CM, Couch FJ (2013) Genetic susceptibility to triple-negative breast cancer. Cancer Res 73(7):2025-2030.
    • (2013) Cancer Res , vol.73 , Issue.7 , pp. 2025-2030
    • Stevens, K.N.1    Vachon, C.M.2    Couch, F.J.3
  • 14
    • 53649103350 scopus 로고    scopus 로고
    • The orphan g protein-coupled receptor 161 is required for leftright patterning
    • Leung T, et al. (2008) The orphan G protein-coupled receptor 161 is required for leftright patterning. Dev Biol 323(1):31-40.
    • (2008) Dev Biol , vol.323 , Issue.1 , pp. 31-40
    • Leung, T.1
  • 15
    • 84872508509 scopus 로고    scopus 로고
    • The ciliary g-protein-coupled receptor gpr161 negatively regulates the sonic hedgehog pathway via camp signaling
    • Mukhopadhyay S, et al. (2013) The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell 152(1-2): 210-223.
    • (2013) Cell , vol.152 , Issue.1-2 , pp. 210-223
    • Mukhopadhyay, S.1
  • 16
    • 84889606709 scopus 로고    scopus 로고
    • A melanocyte lineage program confers resistance to map kinase pathway inhibition
    • Johannessen CM, et al. (2013) A melanocyte lineage program confers resistance to MAP kinase pathway inhibition. Nature 504(7478):138-142.
    • (2013) Nature , vol.504 , Issue.7478 , pp. 138-142
    • Johannessen, C.M.1
  • 17
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • DOI 10.1016/S1046-2023(03)00032-X
    • Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30(3):256-268. (Pubitemid 36677560)
    • (2003) Methods , vol.30 , Issue.3 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 19
    • 84856219974 scopus 로고    scopus 로고
    • Iqgap1 and its binding proteins control diverse biological functions
    • White CD, Erdemir HH, Sacks DB (2012) IQGAP1 and its binding proteins control diverse biological functions. Cell Signal 24(4):826-834.
    • (2012) Cell Signal , vol.24 , Issue.4 , pp. 826-834
    • White, C.D.1    Erdemir, H.H.2    Sacks, D.B.3
  • 20
    • 84873539187 scopus 로고    scopus 로고
    • β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1
    • Alemayehu M, et al. (2013) β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1. PLoS ONE 8(2): e56174.
    • (2013) PLoS ONE , vol.8 , Issue.2
    • Alemayehu, M.1
  • 21
    • 38149036613 scopus 로고    scopus 로고
    • Iqgap1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
    • Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB (2008) IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem 283(2):1008-1017.
    • (2008) J Biol Chem , vol.283 , Issue.2 , pp. 1008-1017
    • Jadeski, L.1    Mataraza, J.M.2    Jeong, H.W.3    Li, Z.4    Sacks, D.B.5
  • 23
    • 77951247324 scopus 로고    scopus 로고
    • Overexpression of iqgap1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion
    • Hayashi H, et al. (2010) Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion. Int J Cancer 126(11): 2563-2574.
    • (2010) Int J Cancer , vol.126 , Issue.11 , pp. 2563-2574
    • Hayashi, H.1
  • 24
    • 84878139116 scopus 로고    scopus 로고
    • A molecular rheostat at the interface of cancer and diabetes
    • Osman MA, Sarkar FH, Rodriguez-Boulan E (2013) A molecular rheostat at the interface of cancer and diabetes. Biochim Biophys Acta 1836(1):166-176.
    • (2013) Biochim Biophys Acta , vol.1836 , Issue.1 , pp. 166-176
    • Osman, M.A.1    Sarkar, F.H.2    Rodriguez-Boulan, E.3
  • 26
    • 68949186350 scopus 로고    scopus 로고
    • Iqgap1 regulates cell proliferation through a novel cdc42-mtor pathway
    • Wang JB, Sonn R, Tekletsadik YK, Samorodnitsky D, OsmanMA (2009) IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway. J Cell Sci 122(Pt 12):2024-2033.
    • (2009) J Cell Sci , vol.122 , Issue.PART 12 , pp. 2024-2033
    • Wang, J.B.1    Sonn, R.2    Tekletsadik, Y.K.3    Samorodnitsky, D.4    Osman, M.A.5
  • 27
    • 84863107745 scopus 로고    scopus 로고
    • A conserved role of iqgap1 in regulating tor complex 1
    • Tekletsadik YK, Sonn R, Osman MA (2012) A conserved role of IQGAP1 in regulating TOR complex 1. J Cell Sci 125(Pt 8):2041-2052.
    • (2012) J Cell Sci , vol.125 , Issue.PART 8 , pp. 2041-2052
    • Tekletsadik, Y.K.1    Sonn, R.2    Osman, M.A.3
  • 28
    • 80051932950 scopus 로고    scopus 로고
    • Iqgap1 protein binds human epidermal growth factor receptor 2 (her2) and modulates trastuzumab resistance
    • White CD, Li Z, Dillon DA, Sacks DB (2011) IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance. J Biol Chem 286(34):29734-29747.
    • (2011) J Biol Chem , vol.286 , Issue.34 , pp. 29734-29747
    • White, C.D.1    Li, Z.2    Dillon, D.A.3    Sacks, D.B.4
  • 29
    • 84884594350 scopus 로고    scopus 로고
    • Harnessing the genome for characterization of g-protein coupled receptors in cancer pathogenesis
    • Feigin M (2013) Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis. FEBS J 280(19):4729-4738.
    • (2013) FEBS J , vol.280 , Issue.19 , pp. 4729-4738
    • Feigin, M.1
  • 31
    • 56349098933 scopus 로고    scopus 로고
    • Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
    • Zhan L, et al. (2008) Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 135(5):865-878.
    • (2008) Cell , vol.135 , Issue.5 , pp. 865-878
    • Zhan, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.