-
1
-
-
0032875356
-
Physiological regulation of G protein-linked signaling
-
Morris AJ, Malbon CC (1999) Physiological regulation of G protein-linked signaling. Physiol Rev 79(4):1373-1430. (Pubitemid 29473319)
-
(1999)
Physiological Reviews
, vol.79
, Issue.4
, pp. 1373-1430
-
-
Morris, A.J.1
Malbon, C.C.2
-
2
-
-
84884594350
-
Harnessing the genome for characterization of g-protein coupled receptors in cancer pathogenesis
-
Feigin ME (2013) Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis. FEBS J 280(19):4729-4738.
-
(2013)
FEBS J
, vol.280
, Issue.19
, pp. 4729-4738
-
-
Feigin, M.E.1
-
3
-
-
78650845707
-
G protein-coupled receptors: Novel targets for drug discovery in cancer
-
Lappano R, Maggiolini M (2011) G protein-coupled receptors: Novel targets for drug discovery in cancer. Nat Rev Drug Discov 10(1):47-60.
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.1
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
4
-
-
33846474121
-
G-protein-coupled receptors and cancer
-
DOI 10.1038/nrc2069, PII NRC2069
-
Dorsam RT, Gutkind JS (2007) G-protein-coupled receptors and cancer. Nat Rev Cancer 7(2):79-94. (Pubitemid 46164746)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.2
, pp. 79-94
-
-
Dorsam, R.T.1
Gutkind, J.S.2
-
5
-
-
84878219891
-
The emerging mutational landscape of g proteins and g-protein-coupled receptors in cancer
-
O'Hayre M, et al. (2013) The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer. Nat Rev Cancer 13(6):412-424.
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.6
, pp. 412-424
-
-
O'Hayre, M.1
-
6
-
-
80054997116
-
Exon capture analysis of g protein-coupled receptors identifies activating mutations in grm3 in melanoma
-
Prickett TD, et al. (2011) Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet 43(11):1119-1126.
-
(2011)
Nat Genet
, vol.43
, Issue.11
, pp. 1119-1126
-
-
Prickett, T.D.1
-
7
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, et al. (2010) Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466(7308):869-873.
-
(2010)
Nature
, vol.466
, Issue.7308
, pp. 869-873
-
-
Kan, Z.1
-
8
-
-
84868320535
-
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
-
Liang H, et al. (2012) Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer. Genome Res 22(11):2120-2129.
-
(2012)
Genome Res
, vol.22
, Issue.11
, pp. 2120-2129
-
-
Liang, H.1
-
9
-
-
78649329196
-
Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing
-
Zhao Q, et al. (2010) Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing. Genome Biol 11(11):R114.
-
(2010)
Genome Biol
, vol.11
, Issue.11
-
-
Zhao, Q.1
-
10
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network
-
Hammerman PS, et al.; Cancer Genome Atlas Research Network (2012) Comprehensive genomic characterization of squamous cell lung cancers. Nature 489(7417): 519-525.
-
(2012)
Nature
, vol.489
, Issue.7417
, pp. 519-525
-
-
Hammerman, P.S.1
-
12
-
-
84875993448
-
Genetic susceptibility to triple-negative breast cancer
-
Stevens KN, Vachon CM, Couch FJ (2013) Genetic susceptibility to triple-negative breast cancer. Cancer Res 73(7):2025-2030.
-
(2013)
Cancer Res
, vol.73
, Issue.7
, pp. 2025-2030
-
-
Stevens, K.N.1
Vachon, C.M.2
Couch, F.J.3
-
13
-
-
41149143108
-
The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development
-
DOI 10.1073/pnas.0705657105
-
Matteson PG, et al. (2008) The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. Proc Natl Acad Sci USA 105(6):2088-2093. (Pubitemid 351439469)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 2088-2093
-
-
Matteson, P.G.1
Desai, J.2
Korstanje, R.3
Lazar, G.4
Borsuk, T.E.5
Rollins, J.6
Kadambi, S.7
Joseph, J.8
Rahman, T.9
Wink, J.10
Benayed, R.11
Paigen, B.12
Millonig, J.H.13
-
14
-
-
53649103350
-
The orphan g protein-coupled receptor 161 is required for leftright patterning
-
Leung T, et al. (2008) The orphan G protein-coupled receptor 161 is required for leftright patterning. Dev Biol 323(1):31-40.
-
(2008)
Dev Biol
, vol.323
, Issue.1
, pp. 31-40
-
-
Leung, T.1
-
15
-
-
84872508509
-
The ciliary g-protein-coupled receptor gpr161 negatively regulates the sonic hedgehog pathway via camp signaling
-
Mukhopadhyay S, et al. (2013) The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell 152(1-2): 210-223.
-
(2013)
Cell
, vol.152
, Issue.1-2
, pp. 210-223
-
-
Mukhopadhyay, S.1
-
16
-
-
84889606709
-
A melanocyte lineage program confers resistance to map kinase pathway inhibition
-
Johannessen CM, et al. (2013) A melanocyte lineage program confers resistance to MAP kinase pathway inhibition. Nature 504(7478):138-142.
-
(2013)
Nature
, vol.504
, Issue.7478
, pp. 138-142
-
-
Johannessen, C.M.1
-
17
-
-
0037603113
-
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
-
DOI 10.1016/S1046-2023(03)00032-X
-
Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30(3):256-268. (Pubitemid 36677560)
-
(2003)
Methods
, vol.30
, Issue.3
, pp. 256-268
-
-
Debnath, J.1
Muthuswamy, S.K.2
Brugge, J.S.3
-
18
-
-
33947264077
-
PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase
-
DOI 10.1016/j.molcel.2007.03.003, PII S1097276507001487
-
Sancak Y, et al. (2007) PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell 25(6):903-915. (Pubitemid 46436534)
-
(2007)
Molecular Cell
, vol.25
, Issue.6
, pp. 903-915
-
-
Sancak, Y.1
Thoreen, C.C.2
Peterson, T.R.3
Lindquist, R.A.4
Kang, S.A.5
Spooner, E.6
Carr, S.A.7
Sabatini, D.M.8
-
19
-
-
84856219974
-
Iqgap1 and its binding proteins control diverse biological functions
-
White CD, Erdemir HH, Sacks DB (2012) IQGAP1 and its binding proteins control diverse biological functions. Cell Signal 24(4):826-834.
-
(2012)
Cell Signal
, vol.24
, Issue.4
, pp. 826-834
-
-
White, C.D.1
Erdemir, H.H.2
Sacks, D.B.3
-
20
-
-
84873539187
-
β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1
-
Alemayehu M, et al. (2013) β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1. PLoS ONE 8(2): e56174.
-
(2013)
PLoS ONE
, vol.8
, Issue.2
-
-
Alemayehu, M.1
-
21
-
-
38149036613
-
Iqgap1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
-
Jadeski L, Mataraza JM, Jeong HW, Li Z, Sacks DB (2008) IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells. J Biol Chem 283(2):1008-1017.
-
(2008)
J Biol Chem
, vol.283
, Issue.2
, pp. 1008-1017
-
-
Jadeski, L.1
Mataraza, J.M.2
Jeong, H.W.3
Li, Z.4
Sacks, D.B.5
-
22
-
-
21044443326
-
IQGAP1: A key regulator of adhesion and migration
-
DOI 10.1242/jcs.02379
-
Noritake J, Watanabe T, Sato K, Wang S, Kaibuchi K (2005) IQGAP1: A key regulator of adhesion and migration. J Cell Sci 118(Pt 10):2085-2092. (Pubitemid 40872832)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.10
, pp. 2085-2092
-
-
Noritake, J.1
Watanabe, T.2
Sato, K.3
Wang, S.4
Kaibuchi, K.5
-
23
-
-
77951247324
-
Overexpression of iqgap1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion
-
Hayashi H, et al. (2010) Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion. Int J Cancer 126(11): 2563-2574.
-
(2010)
Int J Cancer
, vol.126
, Issue.11
, pp. 2563-2574
-
-
Hayashi, H.1
-
24
-
-
84878139116
-
A molecular rheostat at the interface of cancer and diabetes
-
Osman MA, Sarkar FH, Rodriguez-Boulan E (2013) A molecular rheostat at the interface of cancer and diabetes. Biochim Biophys Acta 1836(1):166-176.
-
(2013)
Biochim Biophys Acta
, vol.1836
, Issue.1
, pp. 166-176
-
-
Osman, M.A.1
Sarkar, F.H.2
Rodriguez-Boulan, E.3
-
25
-
-
10344260216
-
Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of Rho-GTPase regulator
-
DOI 10.1074/jbc.M408113200
-
Grohmanova K, et al. (2004) Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of rho-GTPase regulator. J Biol Chem 279(47):48495-48504. (Pubitemid 39625723)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.47
, pp. 48495-48504
-
-
Grohmanova, K.1
Schlaepfer, D.2
Hess, D.3
Gutierrez, P.4
Beck, M.5
Kroschewski, R.6
-
26
-
-
68949186350
-
Iqgap1 regulates cell proliferation through a novel cdc42-mtor pathway
-
Wang JB, Sonn R, Tekletsadik YK, Samorodnitsky D, OsmanMA (2009) IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway. J Cell Sci 122(Pt 12):2024-2033.
-
(2009)
J Cell Sci
, vol.122
, Issue.PART 12
, pp. 2024-2033
-
-
Wang, J.B.1
Sonn, R.2
Tekletsadik, Y.K.3
Samorodnitsky, D.4
Osman, M.A.5
-
27
-
-
84863107745
-
A conserved role of iqgap1 in regulating tor complex 1
-
Tekletsadik YK, Sonn R, Osman MA (2012) A conserved role of IQGAP1 in regulating TOR complex 1. J Cell Sci 125(Pt 8):2041-2052.
-
(2012)
J Cell Sci
, vol.125
, Issue.PART 8
, pp. 2041-2052
-
-
Tekletsadik, Y.K.1
Sonn, R.2
Osman, M.A.3
-
28
-
-
80051932950
-
Iqgap1 protein binds human epidermal growth factor receptor 2 (her2) and modulates trastuzumab resistance
-
White CD, Li Z, Dillon DA, Sacks DB (2011) IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance. J Biol Chem 286(34):29734-29747.
-
(2011)
J Biol Chem
, vol.286
, Issue.34
, pp. 29734-29747
-
-
White, C.D.1
Li, Z.2
Dillon, D.A.3
Sacks, D.B.4
-
29
-
-
84884594350
-
Harnessing the genome for characterization of g-protein coupled receptors in cancer pathogenesis
-
Feigin M (2013) Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis. FEBS J 280(19):4729-4738.
-
(2013)
FEBS J
, vol.280
, Issue.19
, pp. 4729-4738
-
-
Feigin, M.1
-
31
-
-
56349098933
-
Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
-
Zhan L, et al. (2008) Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 135(5):865-878.
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 865-878
-
-
Zhan, L.1
|