MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation

Journal of Biological Chemistry

Volumn 286, Issue 17, 2011, Pages 15010-15021

  McNulty, Dean E ^a,b   Li, Zhigang ^c   White, Colin D ^c   Sacks, David B ^c,d   Annan, Roland S ^a  

^a GLAXOSMITHKLINE   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHOSPHORYLATION; CELLULAR RESPONSE; FUNCTIONAL INTERACTION; IMMUNOPRECIPITATES; IN-CELL; IN-VITRO ANALYSIS; ISOFORMS; KINASE DOMAINS; PHARMACOLOGICAL INHIBITION; SMALL INTERFERING RNA; TYROSINE PHOSPHORYLATION; WILD TYPES;

AMINO ACIDS; CALMODULIN; ENZYMES; MASS SPECTROMETRY; PHOSPHORYLATION; RNA;

SCAFFOLDS (BIOLOGY);

CALCIUM ION; CALMODULIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; PROTEIN KINASE C ALPHA; SERINE; SMALL INTERFERING RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ANIMALS; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS B-RAF; RAS GTPASE-ACTIVATING PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 79955440704     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.227694     Document Type: Article

References (62)

1. Yarden, Y., and Sliwkowski, M. X. (2001) Nat. Rev. Mol. Cell Biol. 2, 127-137
2. Zhang, H., Berezov, A., Wang, Q., Zhang, G., Drebin, J., Murali, R., and Greene, M. I. (2007) J. Clin. Invest. 117, 2051-2058
3. Mendelsohn, J., and Baselga, J. (2000) Oncogene 19, 6550-6565
4. Lowenstein, E. J., Daly, R. J., Batzer, A. G., Li, W., Margolis, B., Lammers, R., Ullrich, A., Skolnik, E. Y., Bar-Sagi, D., and Schlessinger, J. (1992) Cell 70, 431-442
5. Carpenter, G. (2000) BioEssays 22, 697-707
6. Brown, M. D., and Sacks, D. B. (2006) Trends Cell Biol. 16, 242-249
7. Briggs, M. W., and Sacks, D. B. (2003) EMBO Rep. 4, 571-574
8. Briggs, M. W., and Sacks, D. B. (2003) FEBS Lett. 542, 7-11
9. Noritake, J., Watanabe, T., Sato, K., Wang, S., and Kaibuchi, K. (2005) J. Cell Sci. 118, 2085-2092
10. Kuroda, S., Fukata, M., Nakagawa, M., Fujii, K., Nakamura, T., Ookubo, T., Izawa, I., Nagase, T., Nomura, N., Tani, H., Shoji, I., Matsuura, Y., Yonehara, S., and Kaibuchi, K. (1998) Science 281, 832-835
11. Li, Z., Kim, S. H., Higgins, J. M., Brenner, M. B., and Sacks, D. B. (1999) J. Biol. Chem. 274, 37885-37892
12. Briggs, M. W., Li, Z., and Sacks, D. B. (2002) J. Biol. Chem. 277, 7453-7465
13. Johnson, M., Sharma, M., and Henderson, B. R. (2009) Cell. Signal. 21, 1471-1478
14. White, C. D., Brown, M. D., and Sacks, D. B. (2009) FEBS Lett. 583, 1817-1824
15. Brown, M. D., Bry, L., Li, Z., and Sacks, D. B. (2008) J. Biol. Chem. 283, 35212-35222
16. Kolch, W. (2005) Nat. Rev. Mol. Cell Biol. 6, 827-837
17. Morrison, D. K., and Davis, R. J. (2003) Annu. Rev. Cell Dev. Biol. 19, 91-118
18. Kortum, R. L., and Lewis, R. E. (2004) Mol. Cell. Biol. 24, 4407-4416
19. Roy, F., Laberge, G., Douziech, M., Ferland-McCollough, D., and Therrien, M. (2002) Genes Dev. 16, 427-438
20. Ren, J. G., Li, Z., and Sacks, D. B. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 10465-10469
21. Roy, M., Li, Z., and Sacks, D. B. (2004) J. Biol. Chem. 279, 17329-17337
22. Roy, M., Li, Z., and Sacks, D. B. (2005) Mol. Cell. Biol. 25, 7940-7952
23. Bourguignon, L. Y., Gilad, E., Rothman, K., and Peyrollier, K. (2005) J. Biol. Chem. 280, 11961-11972
24. Schrick, C., Fischer, A., Srivastava, D. P., Tronson, N. C., Penzes, P., and Radulovic, J. (2007) Neuron 55, 786-798
25. Pearson, G., Robinson, F., Beers Gibson, T., Xu, B. E., Karandikar, M., Berman, K., and Cobb, M. H. (2001) Endocr. Rev. 22, 153-183
26. Ho, Y. D., Joyal, J. L., Li, Z., and Sacks, D. B. (1999) J. Biol. Chem. 274, 464-470
27. Ren, J. G., Li, Z., Crimmins, D. L., and Sacks, D. B. (2005) J. Biol. Chem. 280, 34548-34557
28. Li, Z., McNulty, D. E., Marler, K. J., Lim, L., Hall, C., Annan, R. S., and Sacks, D. B. (2005) J. Biol. Chem. 280, 13871-13878
29. Joyal, J. L., Annan, R. S., Ho, Y. D., Huddleston, M. E., Carr, S. A., Hart, M. J., and Sacks, D. B. (1997) J. Biol. Chem. 272, 15419-15425
30. McCormack, A. L., Schieltz, D. M., Goode, B., Yang, S., Barnes, G., Drubin, D., and Yates, J. R., 3rd (1997) Anal. Chem. 69, 767-776
31. Ren, J. G., Li, Z., and Sacks, D. B. (2008) J. Biol. Chem. 283, 22972-22982
32. Hart, M. J., Callow, M. G., Souza, B., and Polakis, P. (1996) EMBO J. 15, 2997-3005
33. Mateer, S. C., McDaniel, A. E., Nicolas, V., Habermacher, G. M., Lin, M. J., Cromer, D. A., King, M. E., and Bloom, G. S. (2002) J. Biol. Chem. 277, 12324-12333
34. Jeong, H. W., Li, Z., Brown, M. D., and Sacks, D. B. (2007) J. Biol. Chem. 282, 20752-20762
35. McCallum, S. J., Erickson, J. W., and Cerione, R. A. (1998) J. Biol. Chem. 273, 22537-22544
36. Li, Z., and Sacks, D. B. (2003) J. Biol. Chem. 278, 4347-4352
37. Grohmanova, K., Schlaepfer, D., Hess, D., Gutierrez, P., Beck, M., and Kroschewski, R. (2004) J. Biol. Chem. 279, 48495-48504
38. Singh, A. B., and Harris, R. C. (2005) Cell. Signal. 17, 1183-1193
39. Slater, S. J., Kelly, M. B., Taddeo, F. J., Rubin, E., and Stubbs, C. D. (1994) J. Biol. Chem. 269, 17160-17165
40. Chen, P., Xie, H., and Wells, A. (1996) Mol. Biol. Cell 7, 871-881
41. Welsh, J. B., Gill, G. N., Rosenfeld, M. G., and Wells, A. (1991) J. Cell Biol. 114, 533-543
42. Utz, I., Gekeler, V., Ise, W., Beck, J., Spitaler, M., Grunicke, H., and Hofmann, J. (1996) Anticancer Res. 16, 289-296
43. Kuroda, S., Fukata, M., Kobayashi, K., Nakafuku, M., Nomura, N., Iwamatsu, A., and Kaibuchi, K. (1996) J. Biol. Chem. 271, 23363-23367
44. Casar, B., Arozarena, I., Sanz-Moreno, V., Pinto, A., Agudo-Ibáñez, L., Marais, R., Lewis, R. E., Berciano, M. T., and Crespo, P. (2009) Mol. Cell. Biol. 29, 1338-1353
45. Blagoev, B., Kratchmarova, I., Ong, S. E., Nielsen, M., Foster, L. J., and Mann, M. (2003) Nat. Biotechnol. 21, 315-318
46. Yamaoka-Tojo, M., Ushio-Fukai, M., Hilenski, L., Dikalov, S. I., Chen, Y. E., Tojo, T., Fukai, T., Fujimoto, M., Patrushev, N. A., Wang, N., Kontos, C. D., Bloom, G. S., and Alexander, R. W. (2004) Circ. Res. 95, 276-283
47. Nuriya, M., Oh, S., and Huganir, R. L. (2005) J. Neurochem. 95, 544-552
48. Benseñor, L. B., Kan, H. M., Wang, N., Wallrabe, H., Davidson, L. A., Cai, Y., Schafer, D. A., and Bloom, G. S. (2007) J. Cell Sci. 120, 658-669
49. Sánchez-González, P., Jellali, K., and Villalobo, A. (2010) FEBS J. 277, 327-342
50. Wang, Y., Wang, M., Wang, F., Zhu, M., Ma, Y., Wang, X., and Wu, R. (2008) Int. J. Mol. Med. 22, 79-87
51. Wang, J. B., Sonn, R., Tekletsadik, Y. K., Samorodnitsky, D., and Osman, M. A. (2009) J. Cell Sci. 122, 2024-2033
52. Olsen, J. V., Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P., and Mann, M. (2006) Cell 127, 635-648
53. Livneh, E., Dull, T. J., Berent, E., Prywes, R., Ullrich, A., and Schlessinger, J. (1988) Mol. Cell. Biol. 8, 2302-2308
54. Lund, K. A., Lazar, C. S., Chen, W. S., Walsh, B. J., Welsh, J. B., Herbst, J. J., Walton, G. M., Rosenfeld, M. G., Gill, G. N., and Wiley, H. S. (1990) J. Biol. Chem. 265, 20517-20523
55. Morrison, P., Saltiel, A. R., and Rosner, M. R. (1996) J. Biol. Chem. 271, 12891-12896
56. Wang, X. Q., Yan, Q., Sun, P., Liu, J. W., Go, L., McDaniel, S. M., and Paller, A. S. (2007) Cancer Res. 67, 9986-9995
57. Hubbard, S. R. (2009) Cell 137, 1181-1183
58. Biscardi, J. S., Maa, M. C., Tice, D. A., Cox, M. E., Leu, T. H., and Parsons, S. J. (1999) J. Biol. Chem. 274, 8335-8343
59. Lombardo, C. R., Consler, T. G., and Kassel, D. B. (1995) Biochemistry 34, 16456-16466
60. Sato, K., Sato, A., Aoto, M., and Fukami, Y. (1995) Biochem. Biophys. Res. Commun. 215, 1078-1087
61. Stover, D. R., Becker, M., Liebetanz, J., and Lydon, N. B. (1995) J. Biol. Chem. 270, 15591-15597
62. Meyer, R. D., Sacks, D. B., and Rahimi, N. (2008) PLoS One 3, e3848