Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway

Journal of Cell Science

Volumn 126, Issue 18, 2013, Pages 4121-4135

  Jacquemet, Guillaume ^a   Morgan, Mark R ^a   Byron, Adam ^b   Humphries, Jonathan D ^a   Choi, Colin K ^c   Chen, Christopher S ^c   Caswell, Patrick T ^a   Humphries, Martin J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

FLNa; Integrin; IQGAP1; Migration; Rac1; RacGAP1

Indexed keywords

BETA1 INTEGRIN; FIBRONECTIN; FILAMIN A; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; RAC1 PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CELL MIGRATION; CELL SPREADING; CHEMICAL ANALYSIS; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS;

FLNA; INTEGRIN; IQGAP1; MIGRATION; RAC1; RACGAP1;

ANIMALS; ANTIGENS, CD29; CELL MOVEMENT; FILAMINS; HUMANS; MEMBRANE PROTEINS; MICE; PROTEOMICS; RAC1 GTP-BINDING PROTEIN; RAS GTPASE-ACTIVATING PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 84884381345     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.121988     Document Type: Article

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