Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice

Neurobiology of Disease

Volumn 76, Issue , 2015, Pages 98-111

  Larson, Eloise ^a,b   Fyfe, Ian ^a   Morton, A Jennifer ^a   Monckton, Darren G ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Huntington disease (HD); Mutation; Polyglutamine expansion; R6 2 mice; Somatic instability; Trinucleotide repeat expansion

Indexed keywords

AGE; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CAG REPEAT; CONTROLLED STUDY; CORPUS STRIATUM; GENETIC VARIABILITY; GENOMIC INSTABILITY; GLIA CELL; HUNTINGTON CHOREA; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; TISSUE STRUCTURE; TRINUCLEOTIDE REPEAT; ANIMAL; ANTIBODY SPECIFICITY; BRAIN; DISEASE MODEL; GENETICS; GLIA; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

AGE FACTORS; ALLELES; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NEUROGLIA; ORGAN SPECIFICITY; TRINUCLEOTIDE REPEAT EXPANSION; TRINUCLEOTIDE REPEATS;

EID: 84923641644     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.01.004     Document Type: Article

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