Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1

Human Molecular Genetics

Volumn 12, Issue 21, 2003, Pages 2789-2795

  Watase, Kei ^a   Venken, Koen J T ^a   Sun, Yaling ^a   Orr, Harry T ^b   Zoghbi, Huda Y ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; DNA; GENE PRODUCT; GUANINE; POLYGLUTAMINE; TRANS ACTING FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL SPECIFICITY; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DISEASE TRANSMISSION; DNA DETERMINATION; FEMALE; GENE EXPRESSION; GENETIC STABILITY; HUNTINGTON CHOREA; MALE; MOSAICISM; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPIC VARIATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPINAL CORD; SPINOCEREBELLAR DEGENERATION; TISSUE SPECIFICITY; TRINUCLEOTIDE REPEAT;

ANIMALS; CEREBELLUM; CHROMOSOMAL INSTABILITY; GENOMIC INSTABILITY; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NEURONS; SPINAL CORD; SPINOCEREBELLAR ATAXIAS; TRINUCLEOTIDE REPEATS;

ANIMALIA;

EID: 0242524440     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg300     Document Type: Article

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