Inherited CAG·CTG allele length is a major modifier of somatic mutation length variability in Huntington disease

DNA Repair

Volumn 6, Issue 6, 2007, Pages 789-796

  Veitch, Nicola J ^a   Ennis, Margaret ^a   McAbney, John P ^a   Shelbourne, Peggy F ^a   Monckton, Darren G ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

DNA mutation; Genetic instability; Huntington disease; Mutation detection; Somatic mosaicism; Triplet repeat expansion

Indexed keywords

CELL DNA;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHEEK; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; DNA MODIFICATION; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MAJOR CLINICAL STUDY; MOSAICISM; ONSET AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOMATIC MUTATION; TISSUE SPECIFICITY; TRINUCLEOTIDE REPEAT; DNA REPAIR; GENETIC PROCEDURES; GENETICS; MUTATION; PHENOTYPE;

AGE OF ONSET; ALLELES; DNA REPAIR; GENETIC TECHNIQUES; GENOTYPE; HUMANS; HUNTINGTON DISEASE; MUTATION; PHENOTYPE; POLYMERASE CHAIN REACTION; TRINUCLEOTIDE REPEAT EXPANSION; TRINUCLEOTIDE REPEATS; VARIATION (GENETICS);

EID: 34247567905     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2007.01.002     Document Type: Article

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