Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Cowin, Randi Michelle ^a   Bui, Nghiem ^a   Graham, Deanna ^a   Green, Jennie R ^a   Grueninger, Stephan ^b   Yuva Paylor, Lisa A ^a   Syed, Arsalan U ^a   Weiss, Andreas ^b   Paylor, Richard ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; HTT PROTEIN, HUMAN; NERVE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; C57BL 6 MOUSE; COGNITION; CONGENIC STRAIN; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; FEMALE; GENE INSERTION; GENETIC STABILITY; HUNTINGTON CHOREA; MALE; MENTAL FUNCTION; MOTOR PERFORMANCE; MOUSE; MOUSE STRAIN; NONHUMAN; ONSET AGE; PHENOTYPE; PHYSICAL ACTIVITY; R6 2 MOUSE; ROTAROD TEST; TRANSGENE; TRANSGENIC MOUSE; TRINUCLEOTIDE REPEAT; ANIMAL; ANIMAL BEHAVIOR; AVOIDANCE BEHAVIOR; C57BL MOUSE; CBA MOUSE; CROSS BREEDING; GENETICS; GENOTYPE; HUMAN;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GENOTYPE; HUMANS; HUNTINGTON DISEASE; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PHENOTYPE; TRANSGENES; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 82855172160     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028409     Document Type: Article

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