Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis

Human Molecular Genetics

Volumn 12, Issue 24, 2003, Pages 3359-3367

  Kennedy, Laura ^a   Evans, Elizabeth ^a   Chen, Chiung Mei ^a   Craven, Lyndsey ^a   Detloff, Peter J ^b   Ennis, Margaret ^a   Shelbourne, Peggy F ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; GLUTAMINE; GUANINE; HUNTINGTIN; MUTANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL SELECTION; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE MODEL; DISEASE SEVERITY; GENE FUNCTION; GENE MUTATION; GENETIC CODE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; MOLECULAR BIOLOGY; MOUSE; MOUSE MUTANT; NEUROPATHOLOGY; NONHUMAN; OBSERVATION; ONSET AGE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE SPECIFICITY; TRINUCLEOTIDE REPEAT;

AGE FACTORS; ALLELES; ANIMALS; BRAIN; HUMANS; HUNTINGTON DISEASE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; ORGAN SPECIFICITY; TRINUCLEOTIDE REPEAT EXPANSION;

ANIMALIA;

EID: 0346752132     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg352     Document Type: Article

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