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Volumn 17, Issue 4, 1997, Pages 404-410

Huntington is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; HUNTINGTIN; HD PROTEIN, HUMAN; HDH PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN;

EID: 0030613177     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1297-404     Document Type: Article
Times cited : (434)

References (15)
  • 1
    • 0022876328 scopus 로고
    • Huntington's disease: Pathogenesis and management
    • Martin, J.B. & Gusella, J.F. Huntington's disease: pathogenesis and management. N. Engl. J. Med. 315, 1267-1276 (1986).
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1267-1276
    • Martin, J.B.1    Gusella, J.F.2
  • 2
    • 0022395922 scopus 로고
    • Neuropathological classification of Huntington's disease
    • Vonsattel, J.P. et al. Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 44, 559-577 (1985).
    • (1985) J. Neuropathol. Exp. Neurol. , vol.44 , pp. 559-577
    • Vonsattel, J.P.1
  • 3
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983 (1993).
    • (1993) Cell , vol.72 , pp. 971-983
  • 4
    • 8244246428 scopus 로고    scopus 로고
    • Reduced penetrance of the Huntington's disease mutation
    • McNeil, S.M. et al. Reduced penetrance of the Huntington's disease mutation. Hum. Mol. Genet. 6, 775-779 (1997).
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 775-779
    • McNeil, S.M.1
  • 5
    • 0029997090 scopus 로고    scopus 로고
    • Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
    • Rubinsztein, D.C. et al. Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am. J. Hum. Genet. 59, 16-22 (1996).
    • (1996) Am. J. Hum. Genet. , vol.59 , pp. 16-22
    • Rubinsztein, D.C.1
  • 6
    • 0030948716 scopus 로고    scopus 로고
    • The genetic defect causing Huntington's disease: Repeated in other contexts?
    • Gusella, J.F., Persichetti, F. & MacDonald, M.E. The genetic defect causing Huntington's disease: repeated in other contexts? Mol. Med. 3, 238-246 (1997).
    • (1997) Mol. Med. , vol.3 , pp. 238-246
    • Gusella, J.F.1    Persichetti, F.2    MacDonald, M.E.3
  • 7
    • 0029022840 scopus 로고
    • Abnormal gene product identified in Huntington's disease lymphocytes and brain
    • Ide, K. et al. Abnormal gene product identified in Huntington's disease lymphocytes and brain. Biochem. Biophys. Res. Commun. 209, 1119-1125 (1995).
    • (1995) Biochem. Biophys. Res. Commun. , vol.209 , pp. 1119-1125
    • Ide, K.1
  • 8
    • 0029055601 scopus 로고
    • Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
    • Trottier, Y. et al. Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nature Genet. 10, 104-110 (1995).
    • (1995) Nature Genet. , vol.10 , pp. 104-110
    • Trottier, Y.1
  • 9
    • 0028904293 scopus 로고
    • Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein
    • Jou, Y.S. & Myers, R.M. Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein. Hum. Mol. Genet. 4, 465-469 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 465-469
    • Jou, Y.S.1    Myers, R.M.2
  • 10
    • 0029034511 scopus 로고
    • Widespread expression of Huntington's disease gene (IT15) protein product
    • Sharp, A.H. et al. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron 14, 1065-1074 (1995).
    • (1995) Neuron , vol.14 , pp. 1065-1074
    • Sharp, A.H.1
  • 11
    • 0028989602 scopus 로고
    • Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
    • DiFiglia, M. et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14, 1075-1081 (1995).
    • (1995) Neuron , vol.14 , pp. 1075-1081
    • DiFiglia, M.1
  • 12
    • 0029152808 scopus 로고
    • Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
    • Gutekunst, C.-A. et al. Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc. Natl. Acad. Sci. USA 92, 8710-8714 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8710-8714
    • Gutekunst, C.-A.1
  • 13
    • 0029295607 scopus 로고
    • Normal and expanded Huntington's disease alleles produce distinguishable proteins due to translation across the CAG repeat
    • Persichetti, F. et al. Normal and expanded Huntington's disease alleles produce distinguishable proteins due to translation across the CAG repeat. Mol. Med. 1, 374-383 (1995).
    • (1995) Mol. Med. , vol.1 , pp. 374-383
    • Persichetti, F.1
  • 14
    • 0028972448 scopus 로고
    • Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
    • Trottier, Y. et al. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias. Nature 378, 403-406 (1995).
    • (1995) Nature , vol.378 , pp. 403-406
    • Trottier, Y.1
  • 15
    • 0028677475 scopus 로고
    • Huntington's disease CAG trinucleotide repeats in neuropathologically confirmed post-mortem brains
    • Persichetti, F. et al. Huntington's disease CAG trinucleotide repeats in neuropathologically confirmed post-mortem brains. Neurobiol. Dis. 1, 159-166 (1995).
    • (1995) Neurobiol. Dis. , vol.1 , pp. 159-166
    • Persichetti, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.