Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/1 mouse model of huntington's disease

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Rattray, Ivan ^a   Smith, Edward J ^a   Crum, William R ^a   Walker, Thomas A ^a   Gale, Richard ^a   Bates, Gillian P ^a   Modo, Michel ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOANALYSIS; BEHAVIOR DISORDER; BRAIN ATROPHY; BRAIN SIZE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE MARKER; EX VIVO STUDY; FEMALE; GRAY MATTER; HISTOPATHOLOGY; HUNTINGTON CHOREA; IN VIVO STUDY; LONGITUDINAL STUDY; MALE; MOTOR PERFORMANCE; MOUSE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING;

AGE FACTORS; ANIMALS; BEHAVIORAL SYMPTOMS; BRAIN; CONDITIONING (PSYCHOLOGY); CROSSES, GENETIC; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MAZE LEARNING; MICE; ORGAN SIZE; PHENOTYPE; ROTAROD PERFORMANCE TEST; SPECIES SPECIFICITY;

EID: 84893193971     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084726     Document Type: Article

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