메뉴 건너뛰기




Volumn 91, Issue 6, 1997, Pages 753-763

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

EID: 0031469707     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80464-X     Document Type: Article
Times cited : (327)

References (33)
  • 1
    • 0028220405 scopus 로고
    • Trinucleotide repeats in neurologic diseases: An hypothesis concerning the pathogenesis of Huntington's Disease, Kennedy's Disease, and Spinocerebellar Ataxia Type I
    • Cha, J.-H.J., and Dure, L.S., IV(1994).Trinucleotide repeats in neurologic diseases: an hypothesis concerning the pathogenesis of Huntington's Disease, Kennedy's Disease, and Spinocerebellar Ataxia Type I. Life Sci. 54, 1459-1464.
    • (1994) Life Sci. , vol.54 , pp. 1459-1464
    • Cha, J.-H.J.1    Dure L.S. IV2
  • 4
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtini n neuronal intranuclear inclusions and dystrophic neurites in brain
    • DiFiglia, M., Sapp, E.,Chase, K.O., Davies, S.W., Bates, G.P., Vonsattel, J.P., and Aronin, N. (1997). Aggregation of Huntingtini n neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277, 1990-1993.
    • (1997) Science , vol.277 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 5
    • 0024441554 scopus 로고
    • Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome
    • Dunnett, S.B., Sirinathsinghji, D.J., Heavens, R., Rogers, D.C., and Kuehn, M.R. (1989). Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome. Brain Res. 501, 401-406.
    • (1989) Brain Res. , vol.501 , pp. 401-406
    • Dunnett, S.B.1    Sirinathsinghji, D.J.2    Heavens, R.3    Rogers, D.C.4    Kuehn, M.R.5
  • 6
    • 0023679928 scopus 로고
    • Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome
    • Finger, S., Heavens, R.P., Sirinathsinghji, D.J., Kuehn, M.R., and Dunnett, S.B. (1988). Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome. J. Neurol. Sci. 86, 203-213.
    • (1988) J. Neurol. Sci. , vol.86 , pp. 203-213
    • Finger, S.1    Heavens, R.P.2    Sirinathsinghji, D.J.3    Kuehn, M.R.4    Dunnett, S.B.5
  • 8
    • 0023150598 scopus 로고
    • HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
    • Hooper, M., Hardy, K., Handyside, A., Hunter, S., and Monk, M. (1987). HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326, 292-295.
    • (1987) Nature , vol.326 , pp. 292-295
    • Hooper, M.1    Hardy, K.2    Handyside, A.3    Hunter, S.4    Monk, M.5
  • 9
    • 0030058208 scopus 로고    scopus 로고
    • Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo
    • Ikeda, H., Yamaguchi, M., Sugai, S., Aze, Y., Narumiya, S., and Kakizuka, A. (1996). Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo. Nat. Genet. 13, 196-202.
    • (1996) Nat. Genet. , vol.13 , pp. 196-202
    • Ikeda, H.1    Yamaguchi, M.2    Sugai, S.3    Aze, Y.4    Narumiya, S.5    Kakizuka, A.6
  • 10
    • 0025935431 scopus 로고
    • Amphetamine induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome
    • Jinnah, H.A., Gage, F.H., and Friedmann, T. (1991). Amphetamine induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome. Behav. Neurosci. 105, 1004-1012.
    • (1991) Behav. Neurosci. , vol.105 , pp. 1004-1012
    • Jinnah, H.A.1    Gage, F.H.2    Friedmann, T.3
  • 11
    • 0027287356 scopus 로고
    • Brain purines in a genetic mouse model of Lesch-Nyhan disease
    • Jinnah, H.A., Page, T., and Friedmann, T. (1993). Brain purines in a genetic mouse model of Lesch-Nyhan disease. J. Neurochem. 60, 2036-2045.
    • (1993) J. Neurochem. , vol.60 , pp. 2036-2045
    • Jinnah, H.A.1    Page, T.2    Friedmann, T.3
  • 13
    • 0028922314 scopus 로고
    • Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: Possible pathogenetic relevance for the (CAG)nexpanded neuronopathies
    • Kazemi-Esfarjani, P., Trifiro, M.A., and Pinsky, L. (1995). Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)nexpanded neuronopathies. Hum. Mol. Genet. 4, 523-527.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 523-527
    • Kazemi-Esfarjani, P.1    Trifiro, M.A.2    Pinsky, L.3
  • 14
    • 0029926760 scopus 로고    scopus 로고
    • Monoclonal antibodies directed against the amino-terminal domain of human TBP cross-react with TBP from other species
    • Lobo Ruppert, S.M., McCulloch, V., Meyer, M., Bautista, C., Falkowski, M., Stunnenberg, H.G., and Hernandez, N. (1996). Monoclonal antibodies directed against the amino-terminal domain of human TBP cross-react with TBP from other species. Hybridoma 15, 55-68.
    • (1996) Hybridoma , vol.15 , pp. 55-68
    • Lobo Ruppert, S.M.1    McCulloch, V.2    Meyer, M.3    Bautista, C.4    Falkowski, M.5    Stunnenberg, H.G.6    Hernandez, N.7
  • 16
    • 0030716768 scopus 로고    scopus 로고
    • The cerebellar leucine rich acidic nuclear protein (LANP) interacts with ataxin-1
    • Matilla, A., Koshy, B., Cummings, C.J., Isobe, T., Orr, H.T., and Zoghbi, H.Y. (1997). The cerebellar leucine rich acidic nuclear protein (LANP) interacts with ataxin-1. Nature 389, 974-978.
    • (1997) Nature , vol.389 , pp. 974-978
    • Matilla, A.1    Koshy, B.2    Cummings, C.J.3    Isobe, T.4    Orr, H.T.5    Zoghbi, H.Y.6
  • 17
    • 0027321548 scopus 로고
    • Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
    • Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W., and Roder, J.C. (1993). Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8424-8428
    • Nagy, A.1    Rossant, J.2    Nagy, R.3    Abramow-Newerly, W.4    Roder, J.C.5
  • 18
    • 0029791355 scopus 로고    scopus 로고
    • Huntington disease: New insights into the relationship between CAG expansion and disease
    • Nasir, J., Goldberg, Y.P., and Hayden, M.R. (1996). Huntington disease: new insights into the relationship between CAG expansion and disease. Hum. Mol. Genet. 5, 1431-1435.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1431-1435
    • Nasir, J.1    Goldberg, Y.P.2    Hayden, M.R.3
  • 19
    • 0029746150 scopus 로고    scopus 로고
    • In vitro synthesis and cloning of long CAG repeats
    • Ordway, J.M., and Detloff, P.J. (1996). In vitro synthesis and cloning of long CAG repeats. Biotechniques 21, 609-610.
    • (1996) Biotechniques , vol.21 , pp. 609-610
    • Ordway, J.M.1    Detloff, P.J.2
  • 20
    • 0030434731 scopus 로고    scopus 로고
    • Toward understanding polyglutamine-induced neurological disease in spinocerebellar ataxia type 1
    • Orr H.T., and Zoghbi, H.Y. (1996). Toward understanding polyglutamine-induced neurological disease in spinocerebellar ataxia type 1. Cold Spring Harb. Symp. Quant. Biol. 61, 649-657.
    • (1996) Cold Spring Harb. Symp. Quant. Biol. , vol.61 , pp. 649-657
    • Orr, H.T.1    Zoghbi, H.Y.2
  • 22
    • 0002476699 scopus 로고
    • The clinical neurology of Huntington's disease
    • P.S. Harper, ed. (London: W.B. Saunders Company Ltd.)
    • Quarrell, O., and Harper, P. (1991). The clinical neurology of Huntington's disease. In Huntington's Disease, P.S. Harper, ed. (London: W.B. Saunders Company Ltd.), pp. 37-80.
    • (1991) Huntington's Disease , pp. 37-80
    • Quarrell, O.1    Harper, P.2
  • 23
    • 0030985156 scopus 로고    scopus 로고
    • The complex pathology of trinucleotide repeats
    • Reddy, R.S., and Housman, D.E. (1997). The complex pathology of trinucleotide repeats. Curr. Opin. Cell Biol. 9, 364-372.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 364-372
    • Reddy, R.S.1    Housman, D.E.2
  • 24
    • 0029089172 scopus 로고
    • When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
    • Ross, C.A. (1995). When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron 15, 493-496.
    • (1995) Neuron , vol.15 , pp. 493-496
    • Ross, C.A.1
  • 29
    • 0028972448 scopus 로고
    • Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
    • Trottier, Y., Lutz, Y., Stevanin, G., Imbert, G., Devys, D., Cancel, G., Saudou, F., Weber, C., David, G.,Tora, L., et al. (1995). Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias. Nature 378, 403-406.
    • (1995) Nature , vol.378 , pp. 403-406
    • Trottier, Y.1    Lutz, Y.2    Stevanin, G.3    Imbert, G.4    Devys, D.5    Cancel, G.6    Saudou, F.7    Weber, C.8    David, G.9    Tora, L.10
  • 31
    • 0026708152 scopus 로고
    • Mouse models of hypoxanthine phosphoribosyltransferase deficiency
    • Williamson, D.J., Hooper, M.L., and Melton, D.W. (1992). Mouse models of hypoxanthine phosphoribosyltransferase deficiency. J. Inherit. Metab. Dis. 15, 665-673.
    • (1992) J. Inherit. Metab. Dis. , vol.15 , pp. 665-673
    • Williamson, D.J.1    Hooper, M.L.2    Melton, D.W.3
  • 32
  • 33
    • 0030294445 scopus 로고    scopus 로고
    • The expanding world of ataxins
    • Zoghbi, H.Y. (1996). The expanding world of ataxins. Nat. Genet. 14, 237-238.
    • (1996) Nat. Genet. , vol.14 , pp. 237-238
    • Zoghbi, H.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.