Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress

Molecular Oncology

Volumn 9, Issue 3, 2015, Pages 601-616

  Maya Mendoza, Apolinar ^a   Ostrakova, Jitka ^a   Kosar, Martin ^a,b   Hall, Arnaldur ^a   Duskova, Pavlina ^c   Mistrik, Martin ^c   Merchut Maya, Joanna Maria ^a   Hodny, Zdenek ^b   Bartkova, Jirina ^a   Christensen, Claus ^a   Bartek, Jiri ^a,b,c  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b INSTITUTE OF MATHEMATICS   (Czech Republic)

^c PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

DNA damage response; DNA fork progression; Energy metabolism; Myc; Ras; Replication stress

Indexed keywords

DNA; MYC PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE;

ARTICLE; BIOENERGY; CELL CYCLE ARREST; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA REPLICATION; ENERGY METABOLISM; FIBROBLAST; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NORMAL HUMAN; ONCOGENE MYC; ONCOGENE RAS; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SENESCENCE; U2OS CELL LINE; VELOCITY; CELL DEATH; DNA DAMAGE; GENETICS; METABOLISM; MITOCHONDRION; PHYSIOLOGICAL STRESS; TUMOR CELL LINE;

CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DNA REPLICATION; ENERGY METABOLISM; GENES, RAS; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-MYC; STRESS, PHYSIOLOGICAL;

EID: 84923365887     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.11.001     Document Type: Article

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