Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma

Pigment Cell and Melanoma Research

Volumn 25, Issue 6, 2012, Pages 732-739

  Filipp, Fabian V ^a,b   Ratnikov, Boris ^a   De Ingeniis, Jessica ^a   Smith, Jeffrey W ^a   Osterman, Andrei L ^a   Scott, David A ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glutamine; Metabolism; Mitochondria; NMR; Systems biology

Indexed keywords

ACETYL COENZYME A; ALANINE; ANTINEOPLASTIC AGENT; ARGININE; ARGININE DEIMIDASE; ARGININOSUCCINATE SYNTHASE; B RAF KINASE; CARBON; FATTY ACID SYNTHASE; GLUTAMINE; ISOCITRATE DEHYDROGENASE 2; PROLINE; PYRUVATE DEHYDROGENASE; SERINE; TRACER; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; AUXOTROPHY; CANCER CELL CULTURE; CANCER PATIENT; CARBON METABOLISM; CARBON SOURCE; CELL METABOLISM; CITRIC ACID CYCLE; CLINICAL TRIAL (TOPIC); ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FATTY ACID SYNTHESIS; GAS CHROMATOGRAPHY; GENE MUTATION; GLIOBLASTOMA; GLUCONEOGENESIS; GLYCOLYSIS; HUMAN; IMMUNOGENICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MELANOCYTE; MELANOMA; MELANOMA CELL; METABOLOMICS; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOGENE C MYC; ONCOGENE N RAS; OXIDATION; OXIDATIVE PHOSPHORYLATION; TUMOR CELL;

CITRIC ACID CYCLE; GLUTAMINE; GLYCOLYSIS; HUMANS; MELANOMA; MITOCHONDRIA; SKIN NEOPLASMS;

EID: 84867909952     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12000     Document Type: Article

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