-
1
-
-
0030724731
-
High telomerase activity in primary lung cancers: Association with increased cell proliferation rates and advanced pathologic stage
-
Albanell, J., Lonardo, F., Rusch, V., Engelhardt, M., Langenfeld, J., Han, W., Klimstra, D., Venkatraman, E., Moore, M.A., and Dmitrovsky, E. (1997). High telomerase activity in primary lung cancers: association with increased cell proliferation rates and advanced pathologic stage. J. Natl. Cancer Inst. 89, 1609-1615.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 1609-1615
-
-
Albanell, J.1
Lonardo, F.2
Rusch, V.3
Engelhardt, M.4
Langenfeld, J.5
Han, W.6
Klimstra, D.7
Venkatraman, E.8
Moore, M.A.9
Dmitrovsky, E.10
-
3
-
-
0028096177
-
Functional interactions within adenovirus E1A protein complexes
-
Barbeau, D., Charbonneau, R., Whalen, S.G., Bayley, S.T., and Branton, P.E. (1994). Functional interactions within adenovirus E1A protein complexes. Oncogene 9, 359-373.
-
(1994)
Oncogene
, vol.9
, pp. 359-373
-
-
Barbeau, D.1
Charbonneau, R.2
Whalen, S.G.3
Bayley, S.T.4
Branton, P.E.5
-
4
-
-
0031299239
-
Mouse models for the study of telomerase
-
Blasco, M.A., Lee, H.W., Rizen, M., Hanahan, D., DePinho, R., and Greider, C.W. (1997a). Mouse models for the study of telomerase. Ciba Found. Symp. 211, 160-176.
-
(1997)
Ciba Found. Symp.
, vol.211
, pp. 160-176
-
-
Blasco, M.A.1
Lee, H.W.2
Rizen, M.3
Hanahan, D.4
DePinho, R.5
Greider, C.W.6
-
5
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco, M.A., Lee, H.W., Hande, M.P., Samper, E., Lansdorp, P.M., DePinho, R.A., and Greider, C.W. (1997b). Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91, 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
6
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar, A.G., Ouellette, M., Frolkis, M., Holt, S.E., Chiu, C., Morin, G.B., Harley, C.B., Shay, J.W., Lichtsteiner, S., and Wright, W.E. (1998). Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
7
-
-
0027509346
-
A region in the C-terminus of adenovirus 2/5 E1A protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis, and metastasis
-
Boyd, J.M., Subramanian, T., Schaeper, U., La Regina, M., Bayley, S., and Chinnadurai, D. (1993). A region in the C-terminus of adenovirus 2/5 E1A protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis, and metastasis. EMBO J. 12, 469-478.
-
(1993)
EMBO J.
, vol.12
, pp. 469-478
-
-
Boyd, J.M.1
Subramanian, T.2
Schaeper, U.3
La Regina, M.4
Bayley, S.5
Chinnadurai, D.6
-
8
-
-
0030990049
-
Telomere dynamics and telomerase activity in in vitro immortalised cells
-
Bryan, T.M., and Reddel, R.R. (1997). Telomere dynamics and telomerase activity in in vitro immortalised cells. Eur. J. Cancer 33, 767-773.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 767-773
-
-
Bryan, T.M.1
Reddel, R.R.2
-
9
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan, T.M., Englezou, A., Dalla-Pozza, L., Dunham, M.A., and Reddel, R.R. (1997). Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 3, 1271-1274.
-
(1997)
Nat. Med.
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
10
-
-
0029013631
-
Telomerase activity associated with acquisition of malignancy in human colorectal cancer
-
Chadeneau, C., Hay, K., Hirte, H.W., Gallinger, S., and Bacchetti, S. (1995). Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res. 55, 2533-2536.
-
(1995)
Cancer Res.
, vol.55
, pp. 2533-2536
-
-
Chadeneau, C.1
Hay, K.2
Hirte, H.W.3
Gallinger, S.4
Bacchetti, S.5
-
11
-
-
0033553516
-
p53-deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin, L., Artandi, S.E., Shen, Q., Tam, A., Lee, S.L., Gottleib, G.J., Greider, C.W., and DePinho, R.A. (1999). p53-deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97, 527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottleib, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
12
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
-
Counter, C.M., Hahn, W.C., Wei, W., Caddle, S.D., Beijersbergen, R.L., Lansdorp, P.M., Sedivy, J.M., and Weinberg, R.A. (1998). Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc. Natl. Acad. Sci. USA 95, 14723-14728.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddle, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
13
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
-
Debbas, M., and White, E. (1993). Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev. 7, 546-554.
-
(1993)
Genes Dev.
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
14
-
-
0030700224
-
Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma
-
Dei Tos, A.P., Piccinin, S., Doglioni, C., Vukosavljevic, T., Mentzel, T., Boiocchi, M., and Fletcher, C.D. (1997). Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma. Am. J. Pathol. 151, 1531-1539.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1531-1539
-
-
Dei Tos, A.P.1
Piccinin, S.2
Doglioni, C.3
Vukosavljevic, T.4
Mentzel, T.5
Boiocchi, M.6
Fletcher, C.D.7
-
15
-
-
0032146795
-
E1A signaling to p53 involves the p19(ARF) tumor suppressor
-
de Stanchina, E., McCurrach, M.E., Zindy, F., Shieh, S.Y., Ferbeyre, G., Samuelson, A.V., Roussel, M.F., Sherr, C.J., and Lowe, S.W. (1998). E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev. 12, 2434-2442.
-
(1998)
Genes Dev.
, vol.12
, pp. 2434-2442
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Shieh, S.Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Roussel, M.F.7
Sherr, C.J.8
Lowe, S.W.9
-
16
-
-
0028987481
-
The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains
-
Dorsman, J.C., Hagmeyer, B.M., Veenstra, J., Elfferich, N.N., Zantema, A., and Van Der Eb, A.J. (1995). The N-terminal region of the adenovirus type 5 E1A proteins can repress expression of cellular genes via two distinct but overlapping domains. J. Virol. 69, 2962-2967.
-
(1995)
J. Virol.
, vol.69
, pp. 2962-2967
-
-
Dorsman, J.C.1
Hagmeyer, B.M.2
Veenstra, J.3
Elfferich, N.N.4
Zantema, A.5
Van Der Eb, A.J.6
-
17
-
-
0033672470
-
Telomere maintenance by recombinantion in human cells
-
Dunham, M.A., Neumann, A.A., Fasching, C.L., and Reddel, R.R. (2000). Telomere maintenance by recombinantion in human cells. Nat. Genet. 26, 447-450.
-
(2000)
Nat. Genet.
, vol.26
, pp. 447-450
-
-
Dunham, M.A.1
Neumann, A.A.2
Fasching, C.L.3
Reddel, R.R.4
-
18
-
-
0033595637
-
Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma
-
Ebina, Y., Yamada, H., Fujino, T., Furuta, I., Sakuragi, N., Yamamoto, R., Katoh, M., Oshimura, M., and Fujimoto, S. (1999). Telomerase activity correlates with histo-pathological factors in uterine endometrial carcinoma. Int. J. Cancer 84, 529-532.
-
(1999)
Int. J. Cancer
, vol.84
, pp. 529-532
-
-
Ebina, Y.1
Yamada, H.2
Fujino, T.3
Furuta, I.4
Sakuragi, N.5
Yamamoto, R.6
Katoh, M.7
Oshimura, M.8
Fujimoto, S.9
-
19
-
-
0035177216
-
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
-
Elenbaas, B., Spirio, L., Koerner, F., Fleming, M.D., Zimonjic, D.B., Donaher, J.L., Popescu, N.C., Hahn, W.C., and Weinberg, R.A. (2001). Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 15, 50-65.
-
(2001)
Genes Dev.
, vol.15
, pp. 50-65
-
-
Elenbaas, B.1
Spirio, L.2
Koerner, F.3
Fleming, M.D.4
Zimonjic, D.B.5
Donaher, J.L.6
Popescu, N.C.7
Hahn, W.C.8
Weinberg, R.A.9
-
20
-
-
0028794489
-
Potential role of natural killer cells in controlling tumorigenesis by human T-cell leukemia viruses
-
Feuer, G., Stewart, S.A., Baird, S.M., Lee, F., Feuer, R., and Chen, I.S. (1995). Potential role of natural killer cells in controlling tumorigenesis by human T-cell leukemia viruses. J. Virol. 69, 1328-1333.
-
(1995)
J. Virol.
, vol.69
, pp. 1328-1333
-
-
Feuer, G.1
Stewart, S.A.2
Baird, S.M.3
Lee, F.4
Feuer, R.5
Chen, I.S.6
-
21
-
-
0035839104
-
The p400 complex is an essential E1A transformation target
-
Fuchs, M., Gerber, J., Drapkin, R., Sif, S., Ikura, T., Ogryzko, V., Lane, W.S., Nakatani, Y., and Livingston, D.M. (2001). The p400 complex is an essential E1A transformation target. Cell 106, 297-307.
-
(2001)
Cell
, vol.106
, pp. 297-307
-
-
Fuchs, M.1
Gerber, J.2
Drapkin, R.3
Sif, S.4
Ikura, T.5
Ogryzko, V.6
Lane, W.S.7
Nakatani, Y.8
Livingston, D.M.9
-
22
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
González-Suárez, E., Samper, E., Flores, J.M., and Blasco, M.A. (2000). Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat. Genet. 26, 114-117.
-
(2000)
Nat. Genet.
, vol.26
, pp. 114-117
-
-
González-Suárez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
23
-
-
0034234237
-
CBP/p300 in cell growth, transformation, and development
-
Goodman, R.H., and Smolik, S. (2000). CBP/p300 in cell growth, transformation, and development. Genes Dev. 14, 1553-1577.
-
(2000)
Genes Dev.
, vol.14
, pp. 1553-1577
-
-
Goodman, R.H.1
Smolik, S.2
-
24
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse
-
Greenberg, R.A., Chin, L., Femino, A., Lee, K.H., Gottlieb, G.J., Singer, R.H., Greider, C.W., and DePinho, R.A. (1999). Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 97, 515-525.
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
25
-
-
0033614998
-
Creation of human tumor cells with defined genetic elements
-
Hahn, W.C., Counter, C.M., Lundberg, A.S., Beijersbergen, R.L., Brooks, M.W., and Weinberg, R.A. (1999). Creation of human tumor cells with defined genetic elements. Nature 400, 464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
26
-
-
0036118368
-
Enumeration of the simian virus 40 early region elements necessary for human cell transformation
-
Hahn, W.C., Dessain, S.K., Brooks, M.W., King, J.E., Elenbaas, B., Sabatini, D.M., DeCaprio, J.A., and Weinberg, R.A. (2002). Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol. Cell. Biol. 22, 2111-2123.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2111-2123
-
-
Hahn, W.C.1
Dessain, S.K.2
Brooks, M.W.3
King, J.E.4
Elenbaas, B.5
Sabatini, D.M.6
DeCaprio, J.A.7
Weinberg, R.A.8
-
27
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D., and Weinberg, R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
28
-
-
0033582717
-
MaRX: An approach to genetics in mammalian cells
-
Hannon, G.J., Sun, P., Carnero, A., Xie, L.Y., Maestro, R., Conklin, D.S., and Beach, D. (1999). MaRX: an approach to genetics in mammalian cells. Science 283, 1129-1130.
-
(1999)
Science
, vol.283
, pp. 1129-1130
-
-
Hannon, G.J.1
Sun, P.2
Carnero, A.3
Xie, L.Y.4
Maestro, R.5
Conklin, D.S.6
Beach, D.7
-
29
-
-
0022589970
-
Association of adenovirus early-region 1A proteins with cellular polypeptides
-
Harlow, E., Whyte, P., Franza, B.R., Jr., and Schley, C. (1986). Association of adenovirus early-region 1A proteins with cellular polypeptides. Mol. Cell. Biol. 6, 1579-1589.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 1579-1589
-
-
Harlow, E.1
Whyte, P.2
Franza Jr., B.R.3
Schley, C.4
-
31
-
-
0028263811
-
c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
-
Harrington, E.A., Bennett, M.R., Fanindi, A., and Evan, G.I. (1994). c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13, 3286-3295.
-
(1994)
EMBO J.
, vol.13
, pp. 3286-3295
-
-
Harrington, E.A.1
Bennett, M.R.2
Fanindi, A.3
Evan, G.I.4
-
32
-
-
0028171968
-
Mediation of c-Myc-induced apoptosis by p53
-
Hermeking, H., and Eick, D. (1994). Mediation of c-Myc-induced apoptosis by p53. Science 265, 2091-2093.
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
33
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
Herrera, E., Samper, E., Martin-Caballero, J., Flores, J.M., Lee, H.W., and Blasco, M.A. (1999). Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J. 18, 2950-2960.
-
(1999)
EMBO J.
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
34
-
-
0343750697
-
Impaired germinal center reaction in mice with short telomeres
-
Herrera, E., Martinez, A.C., and Blasco, M.A. (2000). Impaired germinal center reaction in mice with short telomeres. EMBO J. 19, 472-481.
-
(2000)
EMBO J.
, vol.19
, pp. 472-481
-
-
Herrera, E.1
Martinez, A.C.2
Blasco, M.A.3
-
35
-
-
84993876589
-
Correlating telomerase activity levels with human neuroblastoma outcomes
-
Hiyama, E., Hiyama, K., Yokoyama, T., Matsuura, Y., Piatyszek, M.A., and Shay, J.W. (1995). Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med. 1, 249-255.
-
(1995)
Nat. Med.
, vol.1
, pp. 249-255
-
-
Hiyama, E.1
Hiyama, K.2
Yokoyama, T.3
Matsuura, Y.4
Piatyszek, M.A.5
Shay, J.W.6
-
36
-
-
0035135973
-
Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter
-
Hoare, S.F., Bryce, L.A., Wisman, G.B., Burns, S., Going, J.J., van der Zee, A.G., and Keith, W.N. (2001). Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter. Cancer Res. 61, 27-32.
-
(2001)
Cancer Res.
, vol.61
, pp. 27-32
-
-
Hoare, S.F.1
Bryce, L.A.2
Wisman, G.B.3
Burns, S.4
Going, J.J.5
Van Der Zee, A.G.6
Keith, W.N.7
-
37
-
-
0031431785
-
Systematic determination of telomerase activity and telomere length during the progression of human breast cancer in cell culture models
-
Imam, S.A., Kim, M.S., Anker, L., Datar, R.H., Law, R.E., and Taylor, C.R. (1997). Systematic determination of telomerase activity and telomere length during the progression of human breast cancer in cell culture models. Anticancer Res. 17, 4435-4441.
-
(1997)
Anticancer Res.
, vol.17
, pp. 4435-4441
-
-
Imam, S.A.1
Kim, M.S.2
Anker, L.3
Datar, R.H.4
Law, R.E.5
Taylor, C.R.6
-
38
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo, T., Zindy, F., Roussel, M.F., Quelle, D.E., Downing, J.R., Ashmun, R.A., Grosveld, G., and Sherr, C.J. (1997). Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91, 649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
39
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim, N.W., Piatyszek, M.A., Prowse, K.R., Harley, C.B., West, M.D., Ho, P.L., Coviello, G.M., Wright, W.E., Weinrich, S.L., and Shay, J.W. (1994). Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
40
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land, H., Parada, L.F., and Weinberg, R.A. (1983). Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304, 596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
41
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee, H.W., Blasco, M.A., Gottliebb, G.J., Horner, J.W., 2nd, Greider, C.W., and DePinho, R.A. (1998). Essential role of mouse telomerase in highly proliferative organs. Nature 392, 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottliebb, G.J.3
Horner II, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
42
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
Lin, A.W., Barradas, M., Stone, J.C., van Aelst, L., Serrano, M., and Lowe, S.W. (1998). Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev. 12, 3008-3019.
-
(1998)
Genes Dev.
, vol.12
, pp. 3008-3019
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
Van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
43
-
-
0027262606
-
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
-
Lowe, S.W., and Ruley, H.E. (1993). Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev. 7, 535-545.
-
(1993)
Genes Dev.
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
44
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe, S.W., Bodis, S., McClatchey, A., Remington, L., Ruley, H.E., Fisher, D.E., Housman, D.E., and Jacks, T. (1994). p53 status and the efficacy of cancer therapy in vivo. Science 266, 807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
45
-
-
0034500453
-
Telomeres and their control
-
McEachern, M.J., Krauskopf, A., and Blackburn, E.H. (2000). Telomeres and their control. Annu. Rev. Genet. 34, 331-358.
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 331-358
-
-
McEachern, M.J.1
Krauskopf, A.2
Blackburn, E.H.3
-
46
-
-
0035117940
-
Telomere length abnormalities in mammalian radiosensitive cells
-
McIlrath, J., Bouffler, S.D., Samper, E., Cuthbert, A., Wojcik, A., Szumiel, I., Bryant, P.E., Riches, A.C., Thompson, A., Blasco, M.A., et al. (2001). Telomere length abnormalities in mammalian radiosensitive cells. Cancer Res. 61, 912-915.
-
(2001)
Cancer Res.
, vol.61
, pp. 912-915
-
-
McIlrath, J.1
Bouffler, S.D.2
Samper, E.3
Cuthbert, A.4
Wojcik, A.5
Szumiel, I.6
Bryant, P.E.7
Riches, A.C.8
Thompson, A.9
Blasco, M.A.10
-
47
-
-
0032493894
-
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins
-
McMahon, S.B., Van Buskirk, H.A., Dugan, K.A., Copeland, T.D., and Cole, M.D. (1998). The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94, 363-374.
-
(1998)
Cell
, vol.94
, pp. 363-374
-
-
McMahon, S.B.1
Van Buskirk, H.A.2
Dugan, K.A.3
Copeland, T.D.4
Cole, M.D.5
-
48
-
-
0033578386
-
A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor
-
Meloni, A.R., Smith, E.J., and Nevins, J.R. (1999). A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor. Proc. Natl. Acad. Sci. USA 96, 9574-9579.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9574-9579
-
-
Meloni, A.R.1
Smith, E.J.2
Nevins, J.R.3
-
49
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells during immortalization
-
Meyerson, M., Counter, C.M., Eaton, E.N., Ellisen, L.W., Steiner, P., Caddle, S.D., Ziaugra, L., Beijersbergen, R.L., Davidoff, M.J., Liu, Q., et al. (1997). hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells during immortalization. Cell 90, 785-795.
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
Counter, C.M.2
Eaton, E.N.3
Ellisen, L.W.4
Steiner, P.5
Caddle, S.D.6
Ziaugra, L.7
Beijersbergen, R.L.8
Davidoff, M.J.9
Liu, Q.10
-
50
-
-
0029089514
-
Loss of telomeric sites in the chromosomes of mus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangements
-
Nanda, I., Schneider-Rasp, S., Winking, H., and Schmid, M. (1995). Loss of telomeric sites in the chromosomes of mus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangements. Chromosome Res. 3, 399-409.
-
(1995)
Chromosome Res.
, vol.3
, pp. 399-409
-
-
Nanda, I.1
Schneider-Rasp, S.2
Winking, H.3
Schmid, M.4
-
51
-
-
0023007274
-
Suppression of tumor growth by senescence in virally transformed human fibroblasts
-
O'Brien, W., Stenman, G., and Sager, R. (1986). Suppression of tumor growth by senescence in virally transformed human fibroblasts. Proc. Natl. Acad. Sci. USA 83, 8659-8663.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 8659-8663
-
-
O'Brien, W.1
Stenman, G.2
Sager, R.3
-
52
-
-
0030895204
-
When checkpoints fail
-
Paulovich, A.G., Toczyski, D.P., and Hartwell, L.H. (1997). When checkpoints fail. Cell 88, 315-322.
-
(1997)
Cell
, vol.88
, pp. 315-322
-
-
Paulovich, A.G.1
Toczyski, D.P.2
Hartwell, L.H.3
-
53
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
Rudolph, K.L., Millard, M., Bosenberg, M.W., and DePinho, R.A. (2001). Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat. Genet. 28, 155-159.
-
(2001)
Nat. Genet.
, vol.28
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
DePinho, R.A.4
-
54
-
-
0020520517
-
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
-
Ruley, H.E. (1983). Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 304, 602-606.
-
(1983)
Nature
, vol.304
, pp. 602-606
-
-
Ruley, H.E.1
-
55
-
-
0026006294
-
Senescence as a mode of tumor suppression
-
Sager, R. (1991). Senescence as a mode of tumor suppression. Environ. Health Perspect. 93, 59-62.
-
(1991)
Environ. Health Perspect.
, vol.93
, pp. 59-62
-
-
Sager, R.1
-
56
-
-
0034280093
-
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang
-
Samper, E., Goytisolo, F.A., Slijepcevic, P., van Buul, P.P., and Blasco, M.A. (2000). Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang. EMBO Rep. 1, 244-252.
-
(2000)
EMBO Rep.
, vol.1
, pp. 244-252
-
-
Samper, E.1
Goytisolo, F.A.2
Slijepcevic, P.3
Van Buul, P.P.4
Blasco, M.A.5
-
57
-
-
0035833257
-
Normal telomere length and chromosomal end capping in poly (ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability
-
Samper, E., Goytisolo, F.A., Menissier-de Murcia, J., Gonzalez-Suarez, E., Cigudosa, J.C., de Murcia, G., and Blasco, M.A. (2001). Normal telomere length and chromosomal end capping in poly (ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability. J. Cell Biol. 154, 49-60.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 49-60
-
-
Samper, E.1
Goytisolo, F.A.2
Menissier-de Murcia, J.3
Gonzalez-Suarez, E.4
Cigudosa, J.C.5
De Murcia, G.6
Blasco, M.A.7
-
58
-
-
0030726461
-
Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins
-
Samuelson, A.V., and Lowe, S.W. (1997). Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins. Proc. Natl. Acad. Sci. USA 94, 12094-12099.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12094-12099
-
-
Samuelson, A.V.1
Lowe, S.W.2
-
59
-
-
0029849620
-
Cancer cell cycles
-
Sherr, C.J. (1996). Cancer cell cycles. Science 274, 1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
60
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
Serrano, M., Lee, H., Chin, L., Cordon-Cardo, C., Beach, D., and DePinho, R.A. (1996). Role of the INK4a locus in tumor suppression and cell mortality. Cell 85, 27-37.
-
(1996)
Cell
, vol.85
, pp. 27-37
-
-
Serrano, M.1
Lee, H.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
DePinho, R.A.6
-
61
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D.H., and Lowe, S.W. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.H.4
Lowe, S.W.5
-
62
-
-
0022799430
-
Activated v-myc and v-ras oncogenes do not transform normal human lymphocytes
-
Stevenson, M., and Volsky, D.J. (1986). Activated v-myc and v-ras oncogenes do not transform normal human lymphocytes. Mol. Cell. Biol. 6, 3410-3417.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 3410-3417
-
-
Stevenson, M.1
Volsky, D.J.2
-
63
-
-
0032531003
-
Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis
-
Tang, R., Cheng, A.J., Wang, J.Y., and Wang, T.C. (1998). Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis. Cancer Res. 58, 4052-4054.
-
(1998)
Cancer Res.
, vol.58
, pp. 4052-4054
-
-
Tang, R.1
Cheng, A.J.2
Wang, J.Y.3
Wang, T.C.4
-
64
-
-
0028871755
-
E1A promotes association between p300 and pRb in multimeric complexes required for normal biological activity
-
Wang, H.H., Moran, E., and Yaciuk, P. (1995). E1A promotes association between p300 and pRb in multimeric complexes required for normal biological activity. J. Virol. 69, 7917-7924.
-
(1995)
J. Virol.
, vol.69
, pp. 7917-7924
-
-
Wang, H.H.1
Moran, E.2
Yaciuk, P.3
-
65
-
-
2642610318
-
Myc activates telomerase
-
Wang, J., Xie, L.Y., Allan, S., Beach, D., and Hannon, G.J. (1998). Myc activates telomerase. Genes Dev. 12, 1769-1774.
-
(1998)
Genes Dev.
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
66
-
-
0032555236
-
Signaling pathways in Ras-mediated tumorigenicity and metastasis
-
Webb, C.P., Van Aelst, L., Wigler, M.H., and Woude, G.F. (1998). Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc. Natl. Acad. Sci. USA 95, 8773-8778.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8773-8778
-
-
Webb, C.P.1
Van Aelst, L.2
Wigler, M.H.3
Woude, G.F.4
-
67
-
-
0023914010
-
Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
-
Whyte, P., Buchkovich, K.J., Horowitz, J.M., Friend, S.H., Raybuck, M., Weinberg, R.A., and Harlow, E. (1988). Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 334, 124-129.
-
(1988)
Nature
, vol.334
, pp. 124-129
-
-
Whyte, P.1
Buchkovich, K.J.2
Horowitz, J.M.3
Friend, S.H.4
Raybuck, M.5
Weinberg, R.A.6
Harlow, E.7
-
68
-
-
0024968181
-
Cellular targets for transformation by the adenovirus E1A proteins
-
Whyte, P., Williamson, N.M., and Harlow, E. (1989). Cellular targets for transformation by the adenovirus E1A proteins. Cell 56, 67-75.
-
(1989)
Cell
, vol.56
, pp. 67-75
-
-
Whyte, P.1
Williamson, N.M.2
Harlow, E.3
-
69
-
-
0029023065
-
Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity, and sensitivity
-
Wright, W.E., Shay, J.W., and Piatyszek, M.A. (1995). Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity, and sensitivity. Nucleic Acids Res. 23, 3794-3795.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3794-3795
-
-
Wright, W.E.1
Shay, J.W.2
Piatyszek, M.A.3
-
70
-
-
0033168057
-
Telomerase activity and human telomerase reverse transcriptase mRNA expression in soft tissue tumors: Correlation with grade, histology, and proliferative activity
-
Yan, P., Coindre, J.M., Benhattar, J., Bosman, F.T., and Guillou, L. (1999). Telomerase activity and human telomerase reverse transcriptase mRNA expression in soft tissue tumors: correlation with grade, histology, and proliferative activity. Cancer Res. 59, 3166-3170.
-
(1999)
Cancer Res.
, vol.59
, pp. 3166-3170
-
-
Yan, P.1
Coindre, J.M.2
Benhattar, J.3
Bosman, F.T.4
Guillou, L.5
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