Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- And insult-dependent manner, and follow expression of p16ink4a

Cell Cycle

Volumn 10, Issue 3, 2011, Pages 457-468

  Kosar, Martin ^a,b   Bartkova, Jirina ^b   Hubackova, Sona ^a   Hodny, Zdenek ^a   Lukas, Jiri ^b   Bartek, Jiri ^a,b  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

Activated Ras oncogene; Bacterial toxin; DNA damage response; Etoposide; Histone 3 trimethylated on lysine 9; Hydroxyurea; Replication stress; Senescence associated heterochromatin foci

Indexed keywords

CELL NUCLEUS DNA; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DOXORUBICIN; ETOPOSIDE; HISTONE; HISTONE H3; HYDROXYUREA; RAS PROTEIN;

ARTICLE; CARCINOGENESIS; CELL AGING; CELL PROLIFERATION; CELL STRESS; CELL TYPE; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GENOTOXICITY; HETEROCHROMATIN; HUMAN; HUMAN CELL; KERATINOCYTE; ONCOGENE; ONCOGENE RAS; PRECANCER; PROTEIN MODIFICATION; TELOMERE;

BACTERIA (MICROORGANISMS);

EID: 79851493300     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.3.14707     Document Type: Article

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