Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor

Antioxidants and Redox Signaling

Volumn 21, Issue 15, 2014, Pages 2149-2174

  Goldkorn, Tzipora ^a   Filosto, Simone ^a   Chung, Samuel ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CHOLESTEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; LIPID; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTRAL SPHINGOMYELINASE 2; PROTEIN TYROSINE KINASE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN;

APOPTOSIS; CANCER RESISTANCE; CARCINOGENESIS; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CELL SELECTION; CHRONIC LUNG DISEASE; CONFORMATION; DISEASE COURSE; ENDOCYTOSIS; EPITHELIUM CELL; EXOSOME; HUMAN; INFLAMMATION; LIPID RAFT; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; LUNG DEVELOPMENT; LUNG EMPHYSEMA; LUNG INJURY; MOLECULARLY TARGETED THERAPY; NONHUMAN; ONCOGENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; SMOKING; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; LUNG NEOPLASMS; METABOLISM;

NICOTIANA TABACUM;

ANIMALS; APOPTOSIS; BIOSYNTHETIC PATHWAYS; CERAMIDES; HUMANS; LUNG INJURY; LUNG NEOPLASMS; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMOKING;

EID: 84920483431     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5469     Document Type: Review

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