-
1
-
-
7944238044
-
Somatic alterations in the human cancer genome
-
Weir, B., Zhao, X. & Meyerson, M. Somatic alterations in the human cancer genome. Cancer Cell 6, 433-438 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 433-438
-
-
Weir, B.1
Zhao, X.2
Meyerson, M.3
-
2
-
-
9244222261
-
Targeted cancer therapy
-
Sawyers, C. Targeted cancer therapy. Nature 432, 294-297 (2004).
-
(2004)
Nature
, vol.432
, pp. 294-297
-
-
Sawyers, C.1
-
3
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
Pinkel, D. et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nature Genet. 20, 207-211 (1998).
-
(1998)
Nature Genet
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
-
4
-
-
0032823523
-
Genome-wide analysis of DNA copy-number changes using cDNA microarrays
-
Pollack, J. R. et al. Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nature Genet. 23, 41-46 (1999).
-
(1999)
Nature Genet
, vol.23
, pp. 41-46
-
-
Pollack, J.R.1
-
5
-
-
10744230160
-
High-resolution analysis of DNA copy number using oligonucleotide microarrays
-
Bignell, G. R. et al. High-resolution analysis of DNA copy number using oligonucleotide microarrays. Genome Res. 14, 287-295 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 287-295
-
-
Bignell, G.R.1
-
6
-
-
2342453338
-
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays
-
Zhao, X. et al. An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res. 64, 3060-3071 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 3060-3071
-
-
Zhao, X.1
-
7
-
-
21844478747
-
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
-
Garraway, L. A. et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436, 117-122 (2005).
-
(2005)
Nature
, vol.436
, pp. 117-122
-
-
Garraway, L.A.1
-
8
-
-
21344437734
-
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis
-
Zhao, X. et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res. 65, 5561-5570 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 5561-5570
-
-
Zhao, X.1
-
9
-
-
0035793042
-
Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
-
Li, C. & Wong, W. H. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl Acad. Sci. USA 98, 31-36 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 31-36
-
-
Li, C.1
Wong, W.H.2
-
10
-
-
17744413236
-
Model-based analysis of oligonucleotide arrays: Model validation, design issues and standard error application
-
RESEARCH0032
-
Li, C. & Wong, W. H. Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol. 2, RESEARCH0032 (2001).
-
(2001)
Genome Biol
, vol.2
-
-
Li, C.1
Wong, W.H.2
-
11
-
-
12344259648
-
Analysis of array CGH data: From signal ratio to gain and loss of DNA regions
-
Hupe, P., Stransky, N., Thiery, J. P., Radvanyi, F. & Barillot, E. Analysis of array CGH data: from signal ratio to gain and loss of DNA regions. Bioinformatics 20, 3413-3422 (2004).
-
(2004)
Bioinformatics
, vol.20
, pp. 3413-3422
-
-
Hupe, P.1
Stransky, N.2
Thiery, J.P.3
Radvanyi, F.4
Barillot, E.5
-
12
-
-
84945511709
-
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
-
in the press
-
Beroukhim, R. et al. Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma. Proc. Natl Acad Sci. USA. (in the press).
-
Proc. Natl Acad Sci. USA
-
-
Beroukhim, R.1
-
13
-
-
0037037789
-
Chromosomal imbalances in human lung cancer
-
Balsara, B. R. & Testa, J. R. Chromosomal imbalances in human lung cancer. Oncogene 21, 6877-6883 (2002).
-
(2002)
Oncogene
, vol.21
, pp. 6877-6883
-
-
Balsara, B.R.1
Testa, J.R.2
-
14
-
-
33644525896
-
High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH
-
Garnis, C. et al. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int. J. Cancer 118, 1556-1564 (2006).
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1556-1564
-
-
Garnis, C.1
-
15
-
-
22144433675
-
High-resolution genomic profiles of human lung cancer
-
Tonon, G. et al. High-resolution genomic profiles of human lung cancer. Proc. Natl Acad. Sci. USA 102, 9625-9630 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 9625-9630
-
-
Tonon, G.1
-
16
-
-
0028024945
-
Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas
-
Hayashi, N., Sugimoto, Y., Tsuchiya, E., Ogawa, M. & Nakamura, Y. Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas. Biochem. Biophys. Res. Commun. 202, 1426-1430 (1994).
-
(1994)
Biochem. Biophys. Res. Commun
, vol.202
, pp. 1426-1430
-
-
Hayashi, N.1
Sugimoto, Y.2
Tsuchiya, E.3
Ogawa, M.4
Nakamura, Y.5
-
17
-
-
0036645286
-
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
-
Sanchez-Cespedes, M. et al. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. Cancer Res. 62, 3659-3662 (2002).
-
(2002)
Cancer Res
, vol.62
, pp. 3659-3662
-
-
Sanchez-Cespedes, M.1
-
18
-
-
0024452546
-
p53: A frequent target for genetic abnormalities in lung cancer
-
Takahashi, T. et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 246, 491-494 (1989).
-
(1989)
Science
, vol.246
, pp. 491-494
-
-
Takahashi, T.1
-
19
-
-
26944490279
-
Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer
-
Sato, M. et al. Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer. Genes Chromosomes Cancer 44, 405-414 (2005).
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 405-414
-
-
Sato, M.1
-
20
-
-
20144370942
-
A survey of homozygous deletions in human cancer genomes
-
Cox, C. et al. A survey of homozygous deletions in human cancer genomes. Proc. Natl Acad. Sci. USA 102, 4542-4547 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 4542-4547
-
-
Cox, C.1
-
21
-
-
14844303317
-
Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
-
Barnes, A. P. et al. Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium. J. Biol. Chem. 280, 7997-8003 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 7997-8003
-
-
Barnes, A.P.1
-
22
-
-
33646851581
-
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
-
Zhu, C. Q. et al. Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br. J. Cancer 94, 1452-1459 (2006).
-
(2006)
Br. J. Cancer
, vol.94
, pp. 1452-1459
-
-
Zhu, C.Q.1
-
23
-
-
0033719635
-
Frequent amplification of the telomerase reverse transcriptase gene in human tumors
-
Zhang, A. et al. Frequent amplification of the telomerase reverse transcriptase gene in human tumors. Cancer Res. 60, 6230-6235 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 6230-6235
-
-
Zhang, A.1
-
24
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson, D. H. et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J. Clin. Oncol. 22, 2184-2191 (2004).
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
-
25
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler, A. et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J. Med. 355, 2542-2550 (2006).
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
-
26
-
-
0031447594
-
Thyroid transcription factor-1
-
Bingle, C. D. Thyroid transcription factor-1. Int. J. Biochem. Cell Biol. 29, 1471-1473 (1997).
-
(1997)
Int. J. Biochem. Cell Biol
, vol.29
, pp. 1471-1473
-
-
Bingle, C.D.1
-
27
-
-
0028964324
-
Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells
-
Ikeda, K. et al. Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells. J. Biol. Chem. 270, 8108-8114 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 8108-8114
-
-
Ikeda, K.1
-
28
-
-
0033960450
-
-/- embryos
-
-/- embryos. Dev. Dyn. 217, 180-190 (2000).
-
(2000)
Dev. Dyn
, vol.217
, pp. 180-190
-
-
Yuan, B.1
-
29
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
-
Mullighan, C. G. et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446, 758-764 (2007).
-
(2007)
Nature
, vol.446
, pp. 758-764
-
-
Mullighan, C.G.1
-
30
-
-
3843084078
-
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
-
Bamford, S. et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br. J. Cancer 91, 355-358 (2004).
-
(2004)
Br. J. Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
-
31
-
-
1542515338
-
A census of human cancer genes
-
Futreal, P. A. et al. A census of human cancer genes. Nature Rev. Cancer 4, 177-183 (2004).
-
(2004)
Nature Rev. Cancer
, vol.4
, pp. 177-183
-
-
Futreal, P.A.1
-
32
-
-
33646361583
-
GenePattern 2.0
-
Reich, M. et al. GenePattern 2.0. Nature Genet. 38, 500-501 (2006).
-
(2006)
Nature Genet
, vol.38
, pp. 500-501
-
-
Reich, M.1
-
33
-
-
0037316303
-
A comparison of normalization methods for high-density oligonucleotide array data based on variance and bias
-
Bolstad, B. M., Irizarry, R. A., Astrand, M. & Speed, T. P. A comparison of normalization methods for high-density oligonucleotide array data based on variance and bias. Bioinformatics 19, 185-193 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
34
-
-
4444291843
-
Detection of large-scale variation in the human genome
-
Iafrate, A. J. et al. Detection of large-scale variation in the human genome. Nature Genet. 36, 949-951 (2004).
-
(2004)
Nature Genet
, vol.36
, pp. 949-951
-
-
Iafrate, A.J.1
-
35
-
-
2542548405
-
dChipSNP: Significance curve and clustering of SNP-array-based loss-of-heterozygosity data
-
Lin, M. et al. dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data. Bioinformatics 20, 1233-1240 (2004).
-
(2004)
Bioinformatics
, vol.20
, pp. 1233-1240
-
-
Lin, M.1
-
36
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
Rozen, S. & Skaletsky, H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132, 365-386 (2000).
-
(2000)
Methods Mol. Biol
, vol.132
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
37
-
-
0030872838
-
PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
-
Nickerson, D. A., Tobe, V. O. & Taylor, S. L. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing. Nucleic Acids Res. 25, 2745-2751 (1997).
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2745-2751
-
-
Nickerson, D.A.1
Tobe, V.O.2
Taylor, S.L.3
-
38
-
-
2542594616
-
Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer
-
Rubin, M. A. et al. Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer. Cancer Res. 64, 3814-3822 (2004).
-
(2004)
Cancer Res
, vol.64
, pp. 3814-3822
-
-
Rubin, M.A.1
-
39
-
-
33646953271
-
NCI-Navy Medical Oncology Branch cell line data base
-
Phelps, R. M. et al. NCI-Navy Medical Oncology Branch cell line data base. J. Cell. Biochem., Suppl. 24, 32-91 (1996).
-
(1996)
J. Cell. Biochem., Suppl
, vol.24
, pp. 32-91
-
-
Phelps, R.M.1
-
40
-
-
0021928246
-
Intermediate filament and cross-linked envelope expression in human lung tumor cell lines
-
Banks-Schlegel, S. P., Gazdar, A. F. & Harris, C. C. Intermediate filament and cross-linked envelope expression in human lung tumor cell lines. Cancer Res. 45, 1187-1197 (1985).
-
(1985)
Cancer Res
, vol.45
, pp. 1187-1197
-
-
Banks-Schlegel, S.P.1
Gazdar, A.F.2
Harris, C.C.3
-
41
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
-
42
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L. & Trono, D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnol. 15, 871-875 (1997).
-
(1997)
Nature Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
|