메뉴 건너뛰기




Volumn 450, Issue 7171, 2007, Pages 893-898

Characterizing the cancer genome in lung adenocarcinoma

(70)  Weir, Barbara A a,b   Woo, Michele S a   Getz, Gad b   Perner, Sven c,d   Ding, Li e   Beroukhim, Rameen a,b   Lin, William M a,b   Province, Michael A e   Kraja, Aldi e   Johnson, Laura A c   Shah, Kinjal a,b   Sato, Mitsuo f   Thomas, Roman K a,b,g,h   Barletta, Justine A c   Borecki, Ingrid B e   Broderick, Stephen i   Chang, Andrew C j   Chiang, Derek Y a,b   Chirieac, Lucian R c,k   Cho, Jeonghee a   more..


Author keywords

[No Author keywords available]

Indexed keywords

NK2 HOMEOBOX 1 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 36248980204     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06358     Document Type: Article
Times cited : (966)

References (42)
  • 1
    • 7944238044 scopus 로고    scopus 로고
    • Somatic alterations in the human cancer genome
    • Weir, B., Zhao, X. & Meyerson, M. Somatic alterations in the human cancer genome. Cancer Cell 6, 433-438 (2004).
    • (2004) Cancer Cell , vol.6 , pp. 433-438
    • Weir, B.1    Zhao, X.2    Meyerson, M.3
  • 2
    • 9244222261 scopus 로고    scopus 로고
    • Targeted cancer therapy
    • Sawyers, C. Targeted cancer therapy. Nature 432, 294-297 (2004).
    • (2004) Nature , vol.432 , pp. 294-297
    • Sawyers, C.1
  • 3
    • 17344371740 scopus 로고    scopus 로고
    • High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
    • Pinkel, D. et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nature Genet. 20, 207-211 (1998).
    • (1998) Nature Genet , vol.20 , pp. 207-211
    • Pinkel, D.1
  • 4
    • 0032823523 scopus 로고    scopus 로고
    • Genome-wide analysis of DNA copy-number changes using cDNA microarrays
    • Pollack, J. R. et al. Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nature Genet. 23, 41-46 (1999).
    • (1999) Nature Genet , vol.23 , pp. 41-46
    • Pollack, J.R.1
  • 5
    • 10744230160 scopus 로고    scopus 로고
    • High-resolution analysis of DNA copy number using oligonucleotide microarrays
    • Bignell, G. R. et al. High-resolution analysis of DNA copy number using oligonucleotide microarrays. Genome Res. 14, 287-295 (2004).
    • (2004) Genome Res , vol.14 , pp. 287-295
    • Bignell, G.R.1
  • 6
    • 2342453338 scopus 로고    scopus 로고
    • An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays
    • Zhao, X. et al. An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res. 64, 3060-3071 (2004).
    • (2004) Cancer Res , vol.64 , pp. 3060-3071
    • Zhao, X.1
  • 7
    • 21844478747 scopus 로고    scopus 로고
    • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
    • Garraway, L. A. et al. Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature 436, 117-122 (2005).
    • (2005) Nature , vol.436 , pp. 117-122
    • Garraway, L.A.1
  • 8
    • 21344437734 scopus 로고    scopus 로고
    • Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis
    • Zhao, X. et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res. 65, 5561-5570 (2005).
    • (2005) Cancer Res , vol.65 , pp. 5561-5570
    • Zhao, X.1
  • 9
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • Li, C. & Wong, W. H. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl Acad. Sci. USA 98, 31-36 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.H.2
  • 10
    • 17744413236 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Model validation, design issues and standard error application
    • RESEARCH0032
    • Li, C. & Wong, W. H. Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol. 2, RESEARCH0032 (2001).
    • (2001) Genome Biol , vol.2
    • Li, C.1    Wong, W.H.2
  • 11
    • 12344259648 scopus 로고    scopus 로고
    • Analysis of array CGH data: From signal ratio to gain and loss of DNA regions
    • Hupe, P., Stransky, N., Thiery, J. P., Radvanyi, F. & Barillot, E. Analysis of array CGH data: from signal ratio to gain and loss of DNA regions. Bioinformatics 20, 3413-3422 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 3413-3422
    • Hupe, P.1    Stransky, N.2    Thiery, J.P.3    Radvanyi, F.4    Barillot, E.5
  • 12
    • 84945511709 scopus 로고    scopus 로고
    • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
    • in the press
    • Beroukhim, R. et al. Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma. Proc. Natl Acad Sci. USA. (in the press).
    • Proc. Natl Acad Sci. USA
    • Beroukhim, R.1
  • 13
    • 0037037789 scopus 로고    scopus 로고
    • Chromosomal imbalances in human lung cancer
    • Balsara, B. R. & Testa, J. R. Chromosomal imbalances in human lung cancer. Oncogene 21, 6877-6883 (2002).
    • (2002) Oncogene , vol.21 , pp. 6877-6883
    • Balsara, B.R.1    Testa, J.R.2
  • 14
    • 33644525896 scopus 로고    scopus 로고
    • High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH
    • Garnis, C. et al. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int. J. Cancer 118, 1556-1564 (2006).
    • (2006) Int. J. Cancer , vol.118 , pp. 1556-1564
    • Garnis, C.1
  • 15
    • 22144433675 scopus 로고    scopus 로고
    • High-resolution genomic profiles of human lung cancer
    • Tonon, G. et al. High-resolution genomic profiles of human lung cancer. Proc. Natl Acad. Sci. USA 102, 9625-9630 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 9625-9630
    • Tonon, G.1
  • 16
    • 0028024945 scopus 로고
    • Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas
    • Hayashi, N., Sugimoto, Y., Tsuchiya, E., Ogawa, M. & Nakamura, Y. Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas. Biochem. Biophys. Res. Commun. 202, 1426-1430 (1994).
    • (1994) Biochem. Biophys. Res. Commun , vol.202 , pp. 1426-1430
    • Hayashi, N.1    Sugimoto, Y.2    Tsuchiya, E.3    Ogawa, M.4    Nakamura, Y.5
  • 17
    • 0036645286 scopus 로고    scopus 로고
    • Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
    • Sanchez-Cespedes, M. et al. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. Cancer Res. 62, 3659-3662 (2002).
    • (2002) Cancer Res , vol.62 , pp. 3659-3662
    • Sanchez-Cespedes, M.1
  • 18
    • 0024452546 scopus 로고
    • p53: A frequent target for genetic abnormalities in lung cancer
    • Takahashi, T. et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 246, 491-494 (1989).
    • (1989) Science , vol.246 , pp. 491-494
    • Takahashi, T.1
  • 19
    • 26944490279 scopus 로고    scopus 로고
    • Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer
    • Sato, M. et al. Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer. Genes Chromosomes Cancer 44, 405-414 (2005).
    • (2005) Genes Chromosomes Cancer , vol.44 , pp. 405-414
    • Sato, M.1
  • 20
    • 20144370942 scopus 로고    scopus 로고
    • A survey of homozygous deletions in human cancer genomes
    • Cox, C. et al. A survey of homozygous deletions in human cancer genomes. Proc. Natl Acad. Sci. USA 102, 4542-4547 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4542-4547
    • Cox, C.1
  • 21
    • 14844303317 scopus 로고    scopus 로고
    • Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium
    • Barnes, A. P. et al. Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium. J. Biol. Chem. 280, 7997-8003 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 7997-8003
    • Barnes, A.P.1
  • 22
    • 33646851581 scopus 로고    scopus 로고
    • Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
    • Zhu, C. Q. et al. Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br. J. Cancer 94, 1452-1459 (2006).
    • (2006) Br. J. Cancer , vol.94 , pp. 1452-1459
    • Zhu, C.Q.1
  • 23
    • 0033719635 scopus 로고    scopus 로고
    • Frequent amplification of the telomerase reverse transcriptase gene in human tumors
    • Zhang, A. et al. Frequent amplification of the telomerase reverse transcriptase gene in human tumors. Cancer Res. 60, 6230-6235 (2000).
    • (2000) Cancer Res , vol.60 , pp. 6230-6235
    • Zhang, A.1
  • 24
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson, D. H. et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J. Clin. Oncol. 22, 2184-2191 (2004).
    • (2004) J. Clin. Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1
  • 25
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler, A. et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J. Med. 355, 2542-2550 (2006).
    • (2006) N. Engl. J. Med , vol.355 , pp. 2542-2550
    • Sandler, A.1
  • 26
    • 0031447594 scopus 로고    scopus 로고
    • Thyroid transcription factor-1
    • Bingle, C. D. Thyroid transcription factor-1. Int. J. Biochem. Cell Biol. 29, 1471-1473 (1997).
    • (1997) Int. J. Biochem. Cell Biol , vol.29 , pp. 1471-1473
    • Bingle, C.D.1
  • 27
    • 0028964324 scopus 로고
    • Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells
    • Ikeda, K. et al. Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells. J. Biol. Chem. 270, 8108-8114 (1995).
    • (1995) J. Biol. Chem , vol.270 , pp. 8108-8114
    • Ikeda, K.1
  • 28
    • 0033960450 scopus 로고    scopus 로고
    • -/- embryos
    • -/- embryos. Dev. Dyn. 217, 180-190 (2000).
    • (2000) Dev. Dyn , vol.217 , pp. 180-190
    • Yuan, B.1
  • 29
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan, C. G. et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446, 758-764 (2007).
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1
  • 30
    • 3843084078 scopus 로고    scopus 로고
    • The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
    • Bamford, S. et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br. J. Cancer 91, 355-358 (2004).
    • (2004) Br. J. Cancer , vol.91 , pp. 355-358
    • Bamford, S.1
  • 31
    • 1542515338 scopus 로고    scopus 로고
    • A census of human cancer genes
    • Futreal, P. A. et al. A census of human cancer genes. Nature Rev. Cancer 4, 177-183 (2004).
    • (2004) Nature Rev. Cancer , vol.4 , pp. 177-183
    • Futreal, P.A.1
  • 32
    • 33646361583 scopus 로고    scopus 로고
    • GenePattern 2.0
    • Reich, M. et al. GenePattern 2.0. Nature Genet. 38, 500-501 (2006).
    • (2006) Nature Genet , vol.38 , pp. 500-501
    • Reich, M.1
  • 33
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high-density oligonucleotide array data based on variance and bias
    • Bolstad, B. M., Irizarry, R. A., Astrand, M. & Speed, T. P. A comparison of normalization methods for high-density oligonucleotide array data based on variance and bias. Bioinformatics 19, 185-193 (2003).
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 34
    • 4444291843 scopus 로고    scopus 로고
    • Detection of large-scale variation in the human genome
    • Iafrate, A. J. et al. Detection of large-scale variation in the human genome. Nature Genet. 36, 949-951 (2004).
    • (2004) Nature Genet , vol.36 , pp. 949-951
    • Iafrate, A.J.1
  • 35
    • 2542548405 scopus 로고    scopus 로고
    • dChipSNP: Significance curve and clustering of SNP-array-based loss-of-heterozygosity data
    • Lin, M. et al. dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data. Bioinformatics 20, 1233-1240 (2004).
    • (2004) Bioinformatics , vol.20 , pp. 1233-1240
    • Lin, M.1
  • 36
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • Rozen, S. & Skaletsky, H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132, 365-386 (2000).
    • (2000) Methods Mol. Biol , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 37
    • 0030872838 scopus 로고    scopus 로고
    • PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
    • Nickerson, D. A., Tobe, V. O. & Taylor, S. L. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing. Nucleic Acids Res. 25, 2745-2751 (1997).
    • (1997) Nucleic Acids Res , vol.25 , pp. 2745-2751
    • Nickerson, D.A.1    Tobe, V.O.2    Taylor, S.L.3
  • 38
    • 2542594616 scopus 로고    scopus 로고
    • Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer
    • Rubin, M. A. et al. Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer. Cancer Res. 64, 3814-3822 (2004).
    • (2004) Cancer Res , vol.64 , pp. 3814-3822
    • Rubin, M.A.1
  • 39
    • 33646953271 scopus 로고    scopus 로고
    • NCI-Navy Medical Oncology Branch cell line data base
    • Phelps, R. M. et al. NCI-Navy Medical Oncology Branch cell line data base. J. Cell. Biochem., Suppl. 24, 32-91 (1996).
    • (1996) J. Cell. Biochem., Suppl , vol.24 , pp. 32-91
    • Phelps, R.M.1
  • 40
    • 0021928246 scopus 로고
    • Intermediate filament and cross-linked envelope expression in human lung tumor cell lines
    • Banks-Schlegel, S. P., Gazdar, A. F. & Harris, C. C. Intermediate filament and cross-linked envelope expression in human lung tumor cell lines. Cancer Res. 45, 1187-1197 (1985).
    • (1985) Cancer Res , vol.45 , pp. 1187-1197
    • Banks-Schlegel, S.P.1    Gazdar, A.F.2    Harris, C.C.3
  • 41
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 42
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L. & Trono, D. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nature Biotechnol. 15, 871-875 (1997).
    • (1997) Nature Biotechnol , vol.15 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4    Trono, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.