Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD

Chest

Volumn 117, Issue 3, 2000, Pages 684-694

  Segura Valdez, Lourdes ^a   Pardo, Annie ^c   Gaxiola, Miguel ^a   Uhal, Bruce D ^b   Becerril, Carina ^a   Selman, Moisés ^a  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Apoptosis; Collagenases; COPD; Emphysema; Gelatinases; Metalloproteinases

Indexed keywords

COLLAGENASE; GELATINASE A; GELATINASE B; STROMELYSIN;

ADULT; AGED; ARTICLE; CELL DEATH; CELL KINETICS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOKING; ZYMOGRAPHY;

EID: 0034101866     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.117.3.684     Document Type: Article

References (41)

1. 1 Burrows B. Course and prognosis in advanced disease. In: Petty TL, ed. Chronic obstructive pulmonary disease. New York, NY: Marcel Dekker, 1985; 31-42
2. 2 Official Statement of the American Thoracic Society, 1987: Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136:225-244
3. 3 Janoff A. Elastases and emphysema: current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 1985; 132:417-433
4. 4 Snider GL. Emphysema: the first two centuries and beyond. Am Rev Respir Dis 1992; 146:1615-1622
5. 5 D'Armiento J, Dalal SS, Okada Y, et al. Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell 1992; 71:955-961
6. 6 Selman M, Montaño M, Ramos C, et al. Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase. Am J Physiol 1996; 271: L734-L743
7. 7 Finlay GA, O'Driscoll LR, Russell KJ, et al. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med 1997; 156:240-247
8. 8 MacNee W, Wiggs B, Belzberg AS, et al. The effect of cigarette smoking on neutrophil kinetics in human lungs. N Engl J Med 1989; 321:924-928
9. 9 Finkelstein R, Fraser RS, Ghezzo H, et al. Alveolar inflammation and its relation to emphysema in smokers. Am J Respir Crit Care Med 1995; 152:1666-1672
10. 10 Hautamaki RD, Kobayashi DK, Senior RM, et al. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997; 277:2002-2004
11. 11 Shipley JM, Doyle GAR, Fliszar CJ, et al. The structural basis for the elastolytic activity of the 92-kDa and 72-kDa gelatinases. J Biol Chem 1996; 271:4335-4341
12. 12 Ohnishi K, Takagi M, Kurokawa Y, et al. Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema. Lab Invest 1998; 78:1077-1087
13. 13 Buckley S, Barsky L, Driscoll B, et al. Apoptosis and DNA damage in type 2 alveolar epithelial cells cultured from hyperoxic rats. Am J Physiol 1998; 274:L714-L720
14. 14 Jyonouchi H, Sun S, Abiru T, et al. The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells. Am J Respir Cell Mol Biol 1998; 19:426-436
15. 15 Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994; 15:7-10
16. 16 Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994; 124:619-626
17. 17 Meredith JE, Fazeli B, Schwartz MA. The extracellular matrix as a cell survival factor. Mol Biol Cell 1993; 4:953-961
18. 18 Hoyt DG, Mannix RJ, Gerritsen ME, et al. Integrins inhibit LPS-induced DNA strand breakage in cultured lung endothelial ceUs. Am J Physiol 1996; 270:L689-L694
19. 19 ATS Statement. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease: inpatient management of COPD. Am J Respir Crit Care Med 1995; 152(Suppl):S78-S83
20. 20 Selman M, Pardo A, Barquín N, et al. Collagenase and collagenase inhibitors in bronchoalveolar lavage fluids. Chest 1991; 100:151-155
21. 21 Pardo A, Barrios R, Maldonado V, et al. Gelatinases A and B are upregulated in lung rats by subacute hyperoxia: pathogenetic implications. Am J Pathol 1998; 153:833-844
22. 22 Lemjabbar H, Gosset P, Lechapt-Zalcman E, et al. Overexpression of alveolar macrophage gelatinase B (MMP-9) in patients with idiopathic pulmonary fibrosis: effect of steroid and immunosuppressive treatment. Am J Respir Cell Mol Biol 1999; 20:903-913
23. 23 Pardo A, Selman M, Ridge K, et al. Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen. Am J Respir Crit Care Med 1996; 154:1067-1075
24. 24 Uhal BD, Joshi I, Hughes WF, et al. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol 1998; 275:L1192-L1199
25. 25 Saetta M, Di Stefano A, Maestrelli P, et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis 1993; 147:301-306
26. 26 Merchant RK, Schwartz DA, Helmers RA, et al. Bronchoalveolar lavage cellularity: the distribution in normal volunteers. Am Rev Respir Dis 1992; 146:448-453
27. 27 Niewoehner DE, Kleinerman J, Rice DB. Pathologic changes in the peripheral airways of young cigarette smokers. N Engl J Med 1974; 291:755-758
28. 28 Bosken CH, Hards J, Gatter K, et al. Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunohistochemistry. Am Rev Respir Dis 1992; 145:911-917
29. 29 Hunninghake GH, Crystal RG. Cigarette smoking and lung destruction: accumulation of neutrophils in lungs of cigarette smokers. Am Rev Respir Dis 1983; 128:833-838
30. 30 Selby C, Drost E, Gillooly M, et al. Neutrophil sequestration in lungs removed at surgery: the effect of microscopic emphysema. Am J Respir Crit Care Med 1994; 149:1526-1533
31. 31 Bosken CH, Doerschuk CM, English D, et al. Neutrophil kinetics during active cigarette smoking in rabbits. J Appl Physiol 1991; 71:830-837
32. 32 MacNee W. Neutrophil traffic and COPD. Eur Respir Rev 1997; 7:124-127
33. 33 Di Stefano A, Maestrelli P, Roggeri A, et al. Upregulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis. Am J Respir Crit Care Med 1994; 149:803-810
34. 34 McCrea KA, Ensor JE, Nall K, et al. Altered cytokine regulation in the lungs of cigarette smokers. Am J Respir Crit Care Med 1994; 150:696-703
35. 35 Wilson R. The role of infection in COPD. Chest 1998; 113(Suppl):242S-248S
36. 36 Welgus HG, Jeffrey JJ, Eisen AZ. The collagen substrate specificity of human skin fibroblast. J Biol Chem 1981; 256:9511-9515
37. 37 Collier IE, Wilhem SM, Eisen AZ, et al. H-ras oncogenetransformed human bronchial epithelial cells (TBE-1) secrete a single metalloproteinase capable of degrading membrane collagen. J Biol Chem 1988; 263:6579-6587
38. 38 Delclaux C, Delacourt C, d'Ortho MP, et al. Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane. Am J Respir Crit Care Med 1996; 14:288-295
39. 39 Sympson CJ, Talhouk RS, Alexander CM, et al. Targeted expression of stromelisin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. J Cell Biol 1994; 125:681-693
40. 40 Vu TH, Shipley JM, Bergers G, et al. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 1998; 93:411-422
41. 41 Trevani AS, Andoegui G, Giordano M, et al. Neutrophil apoptosis induced by proteolytic enzymes. Lab Invest 1996; 74:711-721