Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines

Journal of Biological Chemistry

Volumn 287, Issue 1, 2012, Pages 514-522

  Filosto, Simone ^a   Ashfaq, Majid ^a   Chung, Samuel ^a   Fry, William ^a   Goldkorn, Tzipora ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDES; HUMAN AIRWAY; INITIAL STRUCTURES; PHOSPHORYLATION SITES; PROTEIN STABILITY; SERINE PHOSPHORYLATION; SPHINGOMYELINASE;

AMIDES; AMINO ACIDS; CELL DEATH; MACHINERY; PROTEINS;

PHOSPHORYLATION;

NEUTRAL SPHINGOMYELINASE 2; PHOSPHOPROTEIN; SERINE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PHOSPHORYLATION; PHOSPHORYLATION SITE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE, TUMOR; CONSERVED SEQUENCE; ENZYME STABILITY; EPITHELIAL CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PHOSPHORYLATION; PHOSPHOSERINE; SPHINGOMYELIN PHOSPHODIESTERASE; SUBSTRATE SPECIFICITY;

EID: 84855290523     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315481     Document Type: Article

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