-
1
-
-
58849113557
-
COPD-related morbidity and mortality after smoking cessation: Status of the evidence
-
Godtfredsen NS, Lam TH, Hansel TT, Leon ME, Gray N, Dresler C, Burns DM, Prescott E, Vestbo J. COPD-related morbidity and mortality after smoking cessation: status of the evidence. Eur Respir J 2008;32:844-853.
-
(2008)
Eur Respir J
, vol.32
, pp. 844-853
-
-
Godtfredsen, N.S.1
Lam, T.H.2
Hansel, T.T.3
Leon, M.E.4
Gray, N.5
Dresler, C.6
Burns, D.M.7
Prescott, E.8
Vestbo, J.9
-
2
-
-
79958728217
-
Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years
-
Miller M, Cho JY, Pham A, Friedman PJ, Ramsdell J, Broide DH. Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years. Chest 2011;139:1380-1387.
-
(2011)
Chest
, vol.139
, pp. 1380-1387
-
-
Miller, M.1
Cho, J.Y.2
Pham, A.3
Friedman, P.J.4
Ramsdell, J.5
Broide, D.H.6
-
3
-
-
0035421665
-
Amplification of inflammation in emphysema and its association with latent adenoviral infection
-
Retamales I, Elliott WM, Meshi B, Coxson HO, Pare PD, Sciurba FC, Rogers RM, Hayashi S, Hogg JC. Amplification of inflammation in emphysema and its association with latent adenoviral infection. Am J Respir Crit Care Med 2001;164:469-473. (Pubitemid 32778218)
-
(2001)
American Journal of Respiratory and Critical Care Medicine
, vol.164
, Issue.3
, pp. 469-473
-
-
Retamales, I.1
Elliott, W.M.2
Meshi, B.3
Coxson, H.O.4
Pare, P.D.5
Sciurba, F.C.6
Rogers, R.M.7
Hayashi, S.8
Hogg, J.C.9
-
4
-
-
0038070232
-
Apoptosis and emphysema: The missing link
-
DOI 10.1165/rcmb.F269
-
Tuder RM, Petrache I, Elias JA, Voelkel NF, Henson PM. Apoptosis and emphysema: the missing link. Am J Respir Cell Mol Biol 2003;28:551-554. (Pubitemid 36543401)
-
(2003)
American Journal of Respiratory Cell and Molecular Biology
, vol.28
, Issue.5
, pp. 551-554
-
-
Tuder, R.M.1
Petrache, I.2
Elias, J.A.3
Voelkel, N.F.4
Henson, P.M.5
-
5
-
-
49049112707
-
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
-
Petrache I,Medler TR, Richter AT, Kamocki K, Chukwueke U, Zhen L, Gu Y, Adamowicz J, Schweitzer KS, Hubbard WC, et al. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol 2008;295:L44-L53.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Petrache, I.1
Medler, T.R.2
Richter, A.T.3
Kamocki, K.4
Chukwueke, U.5
Zhen, L.6
Gu, Y.7
Adamowicz, J.8
Schweitzer, K.S.9
Hubbard, W.C.10
-
6
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
DOI 10.1038/nm1238
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, Cho C, Hubbard WC, Berdyshev EV, Tuder RM. Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 2005;11:491-498. (Pubitemid 40685971)
-
(2005)
Nature Medicine
, vol.11
, Issue.5
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
Cho, C.6
Hubbard, W.C.7
Berdyshev, E.V.8
Tuder, R.M.9
-
7
-
-
77954470662
-
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
-
Yoshida T, Mett I, Bhunia AK, Bowman J, Perez M, Zhang L, Gandjeva A, Zhen L, Chukwueke U, Mao T, et al. Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat Med 2010;16:767-773.
-
(2010)
Nat Med
, vol.16
, pp. 767-773
-
-
Yoshida, T.1
Mett, I.2
Bhunia, A.K.3
Bowman, J.4
Perez, M.5
Zhang, L.6
Gandjeva, A.7
Zhen, L.8
Chukwueke, U.9
Mao, T.10
-
8
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, Waltenberger J, Voelkel NF. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 2000;106:1311-1319.
-
(2000)
J Clin Invest
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
Le Cras, T.D.4
Abman, S.5
Hirth, P.K.6
Waltenberger, J.7
Voelkel, N.F.8
-
9
-
-
45249122011
-
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells
-
DOI 10.1165/rcmb.2007-0274OC
-
Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, Skirball J, Kamocki K, Schuchman E, Tuder RM, Petrache I. Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. Am J Respir Cell Mol Biol 2008;38:639-646. (Pubitemid 351841564)
-
(2008)
American Journal of Respiratory Cell and Molecular Biology
, vol.38
, Issue.6
, pp. 639-646
-
-
Medler, T.R.1
Petrusca, D.N.2
Lee, P.J.3
Hubbard, W.C.4
Berdyshev, E.V.5
Skirball, J.6
Kamocki, K.7
Schuchman, E.8
Tuder, R.M.9
Petrache, I.10
-
10
-
-
78650057959
-
Sphingolipidmediated inhibition of apoptotic cell clearance by alveolar macrophages
-
Petrusca DN, Gu Y, Adamowicz JJ, Rush NI, Hubbard WC, Smith PA, Berdyshev EV, Birukov KG, Lee CH, Tuder RM, et al. Sphingolipidmediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem 2010;285:40322-40332.
-
(2010)
J Biol Chem
, vol.285
, pp. 40322-40332
-
-
Petrusca, D.N.1
Gu, Y.2
Adamowicz, J.J.3
Rush, N.I.4
Hubbard, W.C.5
Smith, P.A.6
Berdyshev, E.V.7
Birukov, K.G.8
Lee, C.H.9
Tuder, R.M.10
-
11
-
-
0033588881
-
Perflubron enhances adenovirus-mediated gene expression in lungs of transgenic mice with chronic alveolar filling
-
DOI 10.1089/10430349950016933
-
Weiss DJ, Strandjord TP, Liggitt D, Clark JG. Perflubron enhances adenovirus-mediated gene expression in lungs of transgenic mice with chronic alveolar filling. Hum Gene Ther 1999;10:2287-2293. (Pubitemid 29459839)
-
(1999)
Human Gene Therapy
, vol.10
, Issue.14
, pp. 2287-2293
-
-
Weiss, D.J.1
Strandjord, T.P.2
Liggitt, D.3
Clark, J.G.4
-
12
-
-
76149139431
-
Stimulation of sphingosine 1 phosphate signaling as an alveolar cell survival strategy in emphysema
-
Diab KJ, Adamowicz JJ, Kamocki K, Rush NI, Garrison J, Gu Y, Schweitzer KS, Skobeleva A, Rajashekhar G, Hubbard WC, et al. Stimulation of sphingosine 1 phosphate signaling as an alveolar cell survival strategy in emphysema. Am J Respir Crit Care Med 2010;181:344-352.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 344-352
-
-
Diab, K.J.1
Adamowicz, J.J.2
Kamocki, K.3
Rush, N.I.4
Garrison, J.5
Gu, Y.6
Schweitzer, K.S.7
Skobeleva, A.8
Rajashekhar, G.9
Hubbard, W.C.10
-
13
-
-
0033790309
-
Quantitative determination of ceramide using diglyceride kinase
-
Perry DK, Bielawska A, Hannun YA. Quantitative determination of ceramide using diglyceride kinase. Methods Enzymol 2000;312:22-31.
-
(2000)
Methods Enzymol
, vol.312
, pp. 22-31
-
-
Perry, D.K.1
Bielawska, A.2
Hannun, Y.A.3
-
14
-
-
79957880378
-
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice
-
ClaussM, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush N, Schweitzer K, Yildirim AÖ, Kamocki K, Fisher AJ, et al. Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. J Clin Invest 2011;121:2470-2479.
-
(2011)
J Clin Invest
, vol.121
, pp. 2470-2479
-
-
Clauss, M.1
Voswinckel, R.2
Rajashekhar, G.3
Sigua, N.L.4
Fehrenbach, H.5
Rush, N.6
Schweitzer, K.7
Yildirim, A.Ö.8
Kamocki, K.9
Fisher, A.J.10
-
15
-
-
0038465920
-
Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade
-
DOI 10.1165/rcmb.2002-0228OC
-
Tuder RM, Zhen L, Cho CY, Taraseviciene-Stewart L, Kasahara Y, Salvemini D, Voelkel NF, Flores SC. Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. Am J Respir Cell Mol Biol 2003;29:88-97. (Pubitemid 36783320)
-
(2003)
American Journal of Respiratory Cell and Molecular Biology
, vol.29
, Issue.1
, pp. 88-97
-
-
Tuder, R.M.1
Zhen, L.2
Cho, C.Y.3
Taraseviciene-Stewart, L.4
Kasahara, Y.5
Salvemini, D.6
Voelkel, N.F.7
Flores, S.C.8
-
16
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis
-
DOI 10.1128/MCB.22.7.2283-2293.2002
-
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, et al. Identification of a novel hypoxiainducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol 2002;22:2283-2293. (Pubitemid 34224633)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
Kalinski, H.11
Kamer, I.12
Rozen, A.13
Mor, O.14
Keshet, E.15
Leshkowitz, D.16
Einat, P.17
Skaliter, R.18
Feinstein, E.19
-
17
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
DOI 10.1172/JCI200421146
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of NRF2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004;114:1248-1259. (Pubitemid 40385296)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
18
-
-
82855181155
-
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: Role of oxidative stress and ceramides
-
Schweitzer KS, Hatoum H, Brown MB, Gupta M, Justice MJ, Beteck B, Van Demark M, Gu Y, Presson RG Jr, Hubbard WC, et al. Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. Am J Physiol Lung Cell Mol Physiol 2011;301:L836-L846.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
-
-
Schweitzer, K.S.1
Hatoum, H.2
Brown, M.B.3
Gupta, M.4
Justice, M.J.5
Beteck, B.6
Van Demark, M.7
Gu, Y.8
Presson Jr., R.G.9
Hubbard, W.C.10
-
19
-
-
0034109119
-
Cigarette smoke extract decreases the expression of vascular endothelial growth factor by cultured cells and triggers apoptosis of pulmonary endothelial cells
-
Tuder RM, Wood K, Taraseviciene L, Flores SC, Voekel NF. Cigarette smoke extract decreases the expression of vascular endothelial growth factor by cultured cells and triggers apoptosis of pulmonary endothelial cells. Chest 2000;117:241S-242S. (Pubitemid 30326966)
-
(2000)
Chest
, vol.117
, Issue.5 SUPPL. 1
-
-
Tuder, R.M.1
Wood, K.2
Taraseviciene, L.3
Flores, S.C.4
Voekel, N.F.5
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