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Volumn 14, Issue 3, 2003, Pages 858-870

Grb2 regulates internalization of EGF receptors through clathrin-coated pits

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CLATHRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN SUBUNIT; RHODAMINE; TRANSCRIPTION FACTOR AP 2; YELLOW FLUORESCENT PROTEIN;

EID: 0037339887     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-08-0532     Document Type: Article
Times cited : (271)

References (28)
  • 1
    • 0029001195 scopus 로고
    • Structural requirements of the epidermal growth factor receptor for tyrosine phosphorylation of eps8 and eps15, substrates lacking Src SH2 homology domains
    • Alvarez, C.V., Shon, K.-J., Miloso, M., and Beguinot, L. (1995). Structural requirements of the epidermal growth factor receptor for tyrosine phosphorylation of eps8 and eps15, substrates lacking Src SH2 homology domains. J. Biol. Chem. 270, 16271-16276.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16271-16276
    • Alvarez, C.V.1    Shon, K.-J.2    Miloso, M.3    Beguinot, L.4
  • 3
    • 0023032789 scopus 로고
    • Functional studies on the EGF receptor with an antibody that recognizes the intracellular portion of the receptor
    • Beguinot, L., Werth, D., Ito, S., Richert, N., Willingham, M.C., and Pastan, I. (1986). Functional studies on the EGF receptor with an antibody that recognizes the intracellular portion of the receptor. J. Biol. Chem. 261, 1801-1807.
    • (1986) J. Biol. Chem. , vol.261 , pp. 1801-1807
    • Beguinot, L.1    Werth, D.2    Ito, S.3    Richert, N.4    Willingham, M.C.5    Pastan, I.6
  • 4
    • 0032567503 scopus 로고    scopus 로고
    • Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera
    • Carter, R.E., and Sorkin, A. (1998). Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera. J. Biol. Chem. 273, 35000-35007.
    • (1998) J. Biol. Chem. , vol.273 , pp. 35000-35007
    • Carter, R.E.1    Sorkin, A.2
  • 5
    • 0026344988 scopus 로고
    • Ligand-induced internalization and increased cell calcium are Mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor
    • Chang, C.-P., J.P.Y. Kao, C.S. Lazar, B.J. Walsh, A. Wells, H.S. Wiley, G.N. Gill, and M.G. Rosenfeld. (1991). Ligand-induced internalization and increased cell calcium are Mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor. J. Biol. Chem. 266, 23467-23470.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23467-23470
    • Chang, C.-P.1    Kao, J.P.Y.2    Lazar, C.S.3    Walsh, B.J.4    Wells, A.5    Wiley, H.S.6    Gill, G.N.7    Rosenfeld, M.G.8
  • 6
    • 0027203952 scopus 로고
    • Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors
    • Chang, C.-P. et al. (1993). Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J. Biol. Chem. 268, 19312-19320.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19312-19320
    • Chang, C.-P.1
  • 7
    • 0024417285 scopus 로고
    • Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation
    • Chen, W.S. et al. (1989). Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59, 33-43.
    • (1989) Cell , vol.59 , pp. 33-43
    • Chen, W.S.1
  • 8
    • 0032438571 scopus 로고    scopus 로고
    • Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
    • Cheng, A.M. et al. (1998). Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. Cell 95, 793-803.
    • (1998) Cell , vol.95 , pp. 793-803
    • Cheng, A.M.1
  • 9
    • 0034698787 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis
    • Confalonieri, S., Salcini, A.E., Puri, C., Tacchetti, C., and Di Fiore, P.P. (2000). Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis. J. Cell Biol. 150, 905-912.
    • (2000) J. Cell Biol. , vol.150 , pp. 905-912
    • Confalonieri, S.1    Salcini, A.E.2    Puri, C.3    Tacchetti, C.4    Di Fiore, P.P.5
  • 10
    • 0029085398 scopus 로고
    • Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells
    • Damke, H., Gossen, M., Freundlieb, S., Bujard, H., and Schmid, S.L. (1995). Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells. Methods Enzymol. 257, 209-220.
    • (1995) Methods Enzymol. , vol.257 , pp. 209-220
    • Damke, H.1    Gossen, M.2    Freundlieb, S.3    Bujard, H.4    Schmid, S.L.5
  • 11
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 12
    • 0035999983 scopus 로고    scopus 로고
    • Coordinated trafficking of Grb2 and Ras during EGF receptor endocytosis visualized in living cells
    • Jiang, X., and Sorkin, A. (2002). Coordinated trafficking of Grb2 and Ras during EGF receptor endocytosis visualized in living cells. Mol. Biol. Cell 13, 1522-1535.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1522-1535
    • Jiang, X.1    Sorkin, A.2
  • 13
    • 0033392493 scopus 로고    scopus 로고
    • Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cb1/Sli-1
    • Levkowitz, G. et al. (1999). Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cb1/Sli-1 [In Process Citation]. Mol. Cell 4, 1029-1040.
    • (1999) Mol. Cell , vol.4 , pp. 1029-1040
    • Levkowitz, G.1
  • 14
    • 0025160570 scopus 로고
    • Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization
    • Lund, K.A., Opresko, L.K., Strarbuck, C., Walsh, B.J., and Wiley, H.S. (1990). Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization, J. Biol. Chem. 265, 15713-13723.
    • (1990) J. Biol. Chem. , vol.265 , pp. 15713-13723
    • Lund, K.A.1    Opresko, L.K.2    Strarbuck, C.3    Walsh, B.J.4    Wiley, H.S.5
  • 15
    • 0033522506 scopus 로고    scopus 로고
    • Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis
    • Nesterov, A., Carter, R.E., Sorkina, T., Gill, G.N., and Sorkin, A. (1999). Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis. EMBO J. 18, 2489-2499.
    • (1999) EMBO J. , vol.18 , pp. 2489-2499
    • Nesterov, A.1    Carter, R.E.2    Sorkina, T.3    Gill, G.N.4    Sorkin, A.5
  • 16
    • 0028034549 scopus 로고
    • Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells
    • Okutani, T., Okabayaski, Y., Kido, Y., Sugimoto, Y., Sakagucki, K., Matuoka, K., Takenawa, T., and Kasuga, M. (1994). Grb2/Ash binds directly to tyrosines 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells. J. Biol. Chem. 269, 31310-31314.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31310-31314
    • Okutani, T.1    Okabayaski, Y.2    Kido, Y.3    Sugimoto, Y.4    Sakagucki, K.5    Matuoka, K.6    Takenawa, T.7    Kasuga, M.8
  • 17
    • 0034801382 scopus 로고    scopus 로고
    • Shc mediates ligand-induced internalization of epidermal growth factor receptors
    • Sakaguchi, K., Okabayashi, Y., and Kasuga, M. (2001). Shc mediates ligand-induced internalization of epidermal growth factor receptors. Biochem. Biophys. Res. Commun. 282, 54-1160.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 54-1160
    • Sakaguchi, K.1    Okabayashi, Y.2    Kasuga, M.3
  • 18
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger, J. (2000). Cell signaling by receptor tyrosine kinases. Cell 103, 211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 19
    • 0030793720 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells
    • She, H.Y., Rockow, S., Tang, J., Nishimura, R., Skolnik, E.Y., Chen, M., Margolis, B., and Li, W. (1997). Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells. Mol. Biol. Cell 8, 1709-1721.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 1709-1721
    • She, H.Y.1    Rockow, S.2    Tang, J.3    Nishimura, R.4    Skolnik, E.Y.5    Chen, M.6    Margolis, B.7    Li, W.8
  • 20
    • 0026687216 scopus 로고
    • Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization
    • Sorkin, A., Helin, K., Waters, C.M., Carpenter, G., and Beguinot, L. (1992). Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. J. Biol. Chem. 267, 8672-8678.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8672-8678
    • Sorkin, A.1    Helin, K.2    Waters, C.M.3    Carpenter, G.4    Beguinot, L.5
  • 21
    • 0029889579 scopus 로고    scopus 로고
    • Epidermal growth factor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif
    • Sorkin, A., Mazzotti, M., Sorkina, T., Scotto, L., and Beguinot, L. (1996). Epidermal growth factor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif. J. Biol. Chem. 271, 13377-13384.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13377-13384
    • Sorkin, A.1    Mazzotti, M.2    Sorkina, T.3    Scotto, L.4    Beguinot, L.5
  • 22
    • 0025830686 scopus 로고
    • Multiple autophosphorylation site mutations of the epidermal growth factor receptor
    • Sorkin, A., Waters, C.M., Overholser, K.A., and Carpenter, G. (1991). Multiple autophosphorylation site mutations of the epidermal growth factor receptor. J. Biol. Chem. 266, 8355-8362.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8355-8362
    • Sorkin, A.1    Waters, C.M.2    Overholser, K.A.3    Carpenter, G.4
  • 23
    • 0037178805 scopus 로고    scopus 로고
    • Effect of tyrosine kinase inhibitors on clathrin coated pit recruitment and internalization of epidermal growth factor receptor
    • Sorkina, T., Huang, F., Beguinot, L., and Sorkin, A. (2002). Effect of tyrosine kinase inhibitors on clathrin coated pit recruitment and internalization of epidermal growth factor receptor. J. Biol. Chem. 277, 27433-27441.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27433-27441
    • Sorkina, T.1    Huang, F.2    Beguinot, L.3    Sorkin, A.4
  • 24
    • 0037075547 scopus 로고    scopus 로고
    • Cb1-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
    • Soubeyran, P., Kowanetz, K., Szymkiewicz, I., Langdon, W.Y., and Dikic, I. (2002). Cb1-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 416, 183-187.
    • (2002) Nature , vol.416 , pp. 183-187
    • Soubeyran, P.1    Kowanetz, K.2    Szymkiewicz, I.3    Langdon, W.Y.4    Dikic, I.5
  • 25
    • 0030036079 scopus 로고    scopus 로고
    • Requirement for the adapter protein GRB2 in EGF receptor endocytosis
    • Wang, Z., and Moran, M.F. (1996). Requirement for the adapter protein GRB2 in EGF receptor endocytosis. Science 272, 1935-1939.
    • (1996) Science , vol.272 , pp. 1935-1939
    • Wang, Z.1    Moran, M.F.2
  • 26
    • 0036469898 scopus 로고    scopus 로고
    • A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
    • Waterman, H., Katz, M., Rubin, C., Shtiegman, K., Lavi, S., Elson, A., Jovin, T., and Yarden, Y. (2002). A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling. EMBO J. 21, 303-313.
    • (2002) EMBO J. , vol.21 , pp. 303-313
    • Waterman, H.1    Katz, M.2    Rubin, C.3    Shtiegman, K.4    Lavi, S.5    Elson, A.6    Jovin, T.7    Yarden, Y.8
  • 27
    • 0023677140 scopus 로고
    • Anomalous binding of epidermal growth factor to A431 cells Is due to the effect of high receptor densities and a saturable endocytic system
    • Wiley, H.S. (1988). Anomalous binding of epidermal growth factor to A431 cells Is due to the effect of high receptor densities and a saturable endocytic system. J. Cell Biol. 107, 801-810.
    • (1988) J. Cell Biol. , vol.107 , pp. 801-810
    • Wiley, H.S.1


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