-
1
-
-
33748747214
-
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
-
Mizutani Y, Kihara A, Igarashi Y, (2006) LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. Biochem J 398: 531-538.
-
(2006)
Biochem J
, vol.398
, pp. 531-538
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
2
-
-
23944483995
-
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
-
Mizutani Y, Kihara A, Igarashi Y, (2005) Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. Biochem J 390: 263-271.
-
(2005)
Biochem J
, vol.390
, pp. 263-271
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
3
-
-
41949140023
-
Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, et al. (2008) Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 283: 5677-5684.
-
(2008)
J Biol Chem
, vol.283
, pp. 5677-5684
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
Epstein, S.4
Park, H.5
-
4
-
-
77649121162
-
Orm family proteins mediate sphingolipid homeostasis
-
Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, et al. Orm family proteins mediate sphingolipid homeostasis. Nature 463: 1048-1053.
-
Nature
, vol.463
, pp. 1048-1053
-
-
Breslow, D.K.1
Collins, S.R.2
Bodenmiller, B.3
Aebersold, R.4
Simons, K.5
-
5
-
-
66349086742
-
Bioactive sphingolipids: metabolism and function
-
Bartke N, Hannun YA, (2009) Bioactive sphingolipids: metabolism and function. J Lipid Res 50 Suppl: S91-96.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Bartke, N.1
Hannun, Y.A.2
-
6
-
-
0038352072
-
BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome
-
Kroesen BJ, Jacobs S, Pettus BJ, Sietsma H, Kok JW, et al. (2003) BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome. J Biol Chem 278: 14723-14731.
-
(2003)
J Biol Chem
, vol.278
, pp. 14723-14731
-
-
Kroesen, B.J.1
Jacobs, S.2
Pettus, B.J.3
Sietsma, H.4
Kok, J.W.5
-
7
-
-
70349973066
-
The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells
-
Renert AF, Leprince P, Dieu M, Renaut J, Raes M, et al. (2009) The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells. J Proteome Res 8: 4810-4822.
-
(2009)
J Proteome Res
, vol.8
, pp. 4810-4822
-
-
Renert, A.F.1
Leprince, P.2
Dieu, M.3
Renaut, J.4
Raes, M.5
-
8
-
-
23044486229
-
Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha
-
Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, et al. (2005) Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha. J Biol Chem 280: 27879-27887.
-
(2005)
J Biol Chem
, vol.280
, pp. 27879-27887
-
-
Osawa, Y.1
Uchinami, H.2
Bielawski, J.3
Schwabe, R.F.4
Hannun, Y.A.5
-
9
-
-
80051927751
-
Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels
-
Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, et al. (2011) Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. J Biol Chem 286: 30022-30033.
-
(2011)
J Biol Chem
, vol.286
, pp. 30022-30033
-
-
Ben-David, O.1
Pewzner-Jung, Y.2
Brenner, O.3
Laviad, E.L.4
Kogot-Levin, A.5
-
10
-
-
77951234061
-
A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways
-
Pewzner-Jung Y, Park H, Laviad EL, Silva LC, Lahiri S, et al. (2010) A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways. J Biol Chem 285: 10902-10910.
-
(2010)
J Biol Chem
, vol.285
, pp. 10902-10910
-
-
Pewzner-Jung, Y.1
Park, H.2
Laviad, E.L.3
Silva, L.C.4
Lahiri, S.5
-
11
-
-
18844434417
-
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
-
Petrache I, Natarajan V, Zhen L, Medler TR, Richter AT, et al. (2005) Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice. Nat Med 11: 491-498.
-
(2005)
Nat Med
, vol.11
, pp. 491-498
-
-
Petrache, I.1
Natarajan, V.2
Zhen, L.3
Medler, T.R.4
Richter, A.T.5
-
12
-
-
45249122011
-
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells
-
Medler TR, Petrusca DN, Lee PJ, Hubbard WC, Berdyshev EV, et al. (2008) Apoptotic sphingolipid signaling by ceramides in lung endothelial cells. Am J Respir Cell Mol Biol 38: 639-646.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 639-646
-
-
Medler, T.R.1
Petrusca, D.N.2
Lee, P.J.3
Hubbard, W.C.4
Berdyshev, E.V.5
-
13
-
-
49049112707
-
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
-
Petrache I, Medler TR, Richter AT, Kamocki K, Chukwueke U, et al. (2008) Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol 295: L44-53.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Petrache, I.1
Medler, T.R.2
Richter, A.T.3
Kamocki, K.4
Chukwueke, U.5
-
14
-
-
79957880378
-
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice
-
Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, et al. (2011) Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. J Clin Invest 121: 2470-2479.
-
(2011)
J Clin Invest
, vol.121
, pp. 2470-2479
-
-
Clauss, M.1
Voswinckel, R.2
Rajashekhar, G.3
Sigua, N.L.4
Fehrenbach, H.5
-
15
-
-
0024300166
-
Transgenes as probes for active chromosomal domains in mouse development
-
Allen ND, Cran DG, Barton SC, Hettle S, Reik W, et al. (1988) Transgenes as probes for active chromosomal domains in mouse development. Nature 333: 852-855.
-
(1988)
Nature
, vol.333
, pp. 852-855
-
-
Allen, N.D.1
Cran, D.G.2
Barton, S.C.3
Hettle, S.4
Reik, W.5
-
16
-
-
84874086182
-
Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain
-
Zigdon H, Kogot-Levin A, Park JW, Goldschmidt R, Kelly S, et al. (2013) Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain. J Biol Chem 288: 4947-4956.
-
(2013)
J Biol Chem
, vol.288
, pp. 4947-4956
-
-
Zigdon, H.1
Kogot-Levin, A.2
Park, J.W.3
Goldschmidt, R.4
Kelly, S.5
-
17
-
-
70450240715
-
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas
-
Imgrund S, Hartmann D, Farwanah H, Eckhardt M, Sandhoff R, et al. (2009) Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas. J Biol Chem 284: 33549-33560.
-
(2009)
J Biol Chem
, vol.284
, pp. 33549-33560
-
-
Imgrund, S.1
Hartmann, D.2
Farwanah, H.3
Eckhardt, M.4
Sandhoff, R.5
-
18
-
-
84871894494
-
RTP801 is Required for Ceramide-Induced Cell-Specific Death in the Murine Lung
-
Kamocki K, Van Demark M, Fisher A, Rush NI, Presson RG Jr, et al. (2013) RTP801 is Required for Ceramide-Induced Cell-Specific Death in the Murine Lung. Am J Respir Cell Mol Biol 48: 87-93.
-
(2013)
Am J Respir Cell Mol Biol
, vol.48
, pp. 87-93
-
-
Kamocki, K.1
Van Demark, M.2
Fisher, A.3
Rush, N.I.4
Presson Jr., R.G.5
-
19
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, et al. (2010) A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363: 1211-1221.
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.P.4
Bouzigon, E.5
|