-
1
-
-
0017103026
-
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts
-
Carpenter G., Cohen S. 125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts. J. Cell Biol. 71:1976;159-171.
-
(1976)
J. Cell Biol.
, vol.71
, pp. 159-171
-
-
Carpenter, G.1
Cohen, S.2
-
2
-
-
0018774018
-
Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431
-
Haigler H.T., McKanna J.A., Cohen S. Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431. J. Cell Biol. 81:1979;382-395.
-
(1979)
J. Cell Biol.
, vol.81
, pp. 382-395
-
-
Haigler, H.T.1
McKanna, J.A.2
Cohen, S.3
-
3
-
-
0037213006
-
Computational modeling of the EGF-receptor system: A paradigm for systems biology
-
Wiley H.S., Shvartsman S.Y., Lauffenburger D.A. Computational modeling of the EGF-receptor system a paradigm for systems biology . Trends Cell Biol. 13:2003;43-50.
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 43-50
-
-
Wiley, H.S.1
Shvartsman, S.Y.2
Lauffenburger, D.A.3
-
4
-
-
2142843806
-
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
-
Pinkas-Kramarski R., Soussan L., Waterman H., Levkowitz G., Alroy I., Klapper L., Lavi S., Seger R., Ratzkin B.J., Sela M., Yarden Y. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 15:1996;2452-2467.
-
(1996)
EMBO J.
, vol.15
, pp. 2452-2467
-
-
Pinkas-Kramarski, R.1
Soussan, L.2
Waterman, H.3
Levkowitz, G.4
Alroy, I.5
Klapper, L.6
Lavi, S.7
Seger, R.8
Ratzkin, B.J.9
Sela, M.10
Yarden, Y.11
-
5
-
-
0031562676
-
Heregulin degradation in the absence of rapid receptor-mediated internalization
-
Baulida J., Carpenter G. Heregulin degradation in the absence of rapid receptor-mediated internalization. Exp. Cell. Res. 232:1997;167-172.
-
(1997)
Exp. Cell. Res.
, vol.232
, pp. 167-172
-
-
Baulida, J.1
Carpenter, G.2
-
6
-
-
0029912203
-
All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
-
Baulida J., Kraus M.H., Alimandi M., Di Fiore P.P., Carpenter G. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271:1996;5251-5257.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5251-5257
-
-
Baulida, J.1
Kraus, M.H.2
Alimandi, M.3
Di Fiore, P.P.4
Carpenter, G.5
-
7
-
-
0032789613
-
Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools
-
Burke P.M., Wiley H.S. Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools. J. Cell. Physiol. 180:1999;448-460.
-
(1999)
J. Cell. Physiol.
, vol.180
, pp. 448-460
-
-
Burke, P.M.1
Wiley, H.S.2
-
8
-
-
0032429019
-
Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells
-
Kuwada S.K., Lund K.A., Li X.F., Cliften P., Amsler K., Opresko L.K., Wiley H.S. Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells. Am. J. Physiol. 275:1998;C1419-C1428.
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Kuwada, S.K.1
Lund, K.A.2
Li, X.F.3
Cliften, P.4
Amsler, K.5
Opresko, L.K.6
Wiley, H.S.7
-
9
-
-
0029752791
-
Endocytosis and molecular sorting
-
Mellman I. Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12:1996;575-625.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 575-625
-
-
Mellman, I.1
-
10
-
-
0028335378
-
Regulation of postendocytic trafficking of the epidermal growth factor receptor through endosomal retention
-
Herbst J.J., Opresko L.K., Walsh B.J., Lauffenburger D.A., Wiley H.S. Regulation of postendocytic trafficking of the epidermal growth factor receptor through endosomal retention. J. Biol. Chem. 269:1994;12865-12873.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12865-12873
-
-
Herbst, J.J.1
Opresko, L.K.2
Walsh, B.J.3
Lauffenburger, D.A.4
Wiley, H.S.5
-
11
-
-
0028916337
-
Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain
-
Opresko L.K., Chang C.P., Will B.H., Burke P.M., Gill G.N., Wiley H.S. Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain. J. Biol. Chem. 270:1995;4325-4333.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4325-4333
-
-
Opresko, L.K.1
Chang, C.P.2
Will, B.H.3
Burke, P.M.4
Gill, G.N.5
Wiley, H.S.6
-
12
-
-
0025160570
-
Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization
-
Lund K.A., Opresko L.K., Starbuck C., Walsh B.J., Wiley H.S. Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization. J. Biol. Chem. 265:1990;15713-15723.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15713-15723
-
-
Lund, K.A.1
Opresko, L.K.2
Starbuck, C.3
Walsh, B.J.4
Wiley, H.S.5
-
13
-
-
0342965191
-
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431
-
Haigler H., Ash J.F., Singer S.J., Cohen S. Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc. Natl. Acad. Sci. USA 75. 1978;3317-3321.
-
(1978)
Proc. Natl. Acad. Sci. USA 75
, pp. 3317-3321
-
-
Haigler, H.1
Ash, J.F.2
Singer, S.J.3
Cohen, S.4
-
14
-
-
0035162703
-
Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
-
Burke P., Schooler K., Wiley H.S. Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking. Mol. Biol. Cell. 12:2001;1897-1910.
-
(2001)
Mol. Biol. Cell.
, vol.12
, pp. 1897-1910
-
-
Burke, P.1
Schooler, K.2
Wiley, H.S.3
-
15
-
-
0032567503
-
Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera
-
Carter R.E., Sorkin A. Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera. J. Biol. Chem. 273:1998;35000-35007.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 35000-35007
-
-
Carter, R.E.1
Sorkin, A.2
-
16
-
-
0025071238
-
Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments
-
Reid P.A., Watts C. Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments. Nature 346. 1990;655-657.
-
(1990)
Nature 346
, pp. 655-657
-
-
Reid, P.A.1
Watts, C.2
-
17
-
-
0025014580
-
Role of the human transferrin receptor cytoplasmic domain in endocytosis: Localization of a specific signal sequence for internalization
-
Jing S.Q., Spencer T., Miller K., Hopkins C., Trowbridge I.S. Role of the human transferrin receptor cytoplasmic domain in endocytosis localization of a specific signal sequence for internalization . J. Cell Biol. 110:1990;283-294.
-
(1990)
J. Cell Biol.
, vol.110
, pp. 283-294
-
-
Jing, S.Q.1
Spencer, T.2
Miller, K.3
Hopkins, C.4
Trowbridge, I.S.5
-
18
-
-
0023664118
-
The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis
-
Davis C.G., van Driel I.R., Russell D.W., Brown M.S., Goldstein J.L. The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis. J. Biol. Chem. 262:1987;4075-4082.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 4075-4082
-
-
Davis, C.G.1
Van Driel, I.R.2
Russell, D.W.3
Brown, M.S.4
Goldstein, J.L.5
-
19
-
-
0025402516
-
Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain
-
McGraw T.E., Maxfield F.R. Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regul. 1:1990;369-377.
-
(1990)
Cell Regul.
, vol.1
, pp. 369-377
-
-
McGraw, T.E.1
Maxfield, F.R.2
-
20
-
-
0025431132
-
Endocytosis via coated pits mediated by glycoprotein receptor in which the cytoplasmic tail is replaced by unrelated sequences
-
Verrey F., Gilbert T., Mellow T., Proulx G., Drickamer K. Endocytosis via coated pits mediated by glycoprotein receptor in which the cytoplasmic tail is replaced by unrelated sequences. Cell Regul. 1:1990;471-486.
-
(1990)
Cell Regul.
, vol.1
, pp. 471-486
-
-
Verrey, F.1
Gilbert, T.2
Mellow, T.3
Proulx, G.4
Drickamer, K.5
-
21
-
-
0025037001
-
Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins
-
Ktistakis N.T., Thomas D., Roth M.G. Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. J. Cell Biol. 111:1990;1393-1407.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 1393-1407
-
-
Ktistakis, N.T.1
Thomas, D.2
Roth, M.G.3
-
22
-
-
0021357886
-
Down regulation of epidermal growth factor receptors: Direct demonstration of receptor degradation in human fibroblasts
-
Stoscheck C.M., Carpenter G. Down regulation of epidermal growth factor receptors direct demonstration of receptor degradation in human fibroblasts . J. Cell Biol. 98:1984;1048-1053.
-
(1984)
J. Cell Biol.
, vol.98
, pp. 1048-1053
-
-
Stoscheck, C.M.1
Carpenter, G.2
-
23
-
-
0021219986
-
Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells
-
Stoscheck C.M., Carpenter G. Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells. J. Cell Physiol. 120:1984;296-302.
-
(1984)
J. Cell Physiol.
, vol.120
, pp. 296-302
-
-
Stoscheck, C.M.1
Carpenter, G.2
-
24
-
-
0025908557
-
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
-
Wiley H.S., Herbst J.J., Walsh B.J., Lauffenburger D.A., Rosenfeld M.G., Gill G.N. The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 266:1991;11083-11094.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11083-11094
-
-
Wiley, H.S.1
Herbst, J.J.2
Walsh, B.J.3
Lauffenburger, D.A.4
Rosenfeld, M.G.5
Gill, G.N.6
-
25
-
-
0028224965
-
Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions
-
French A.R., Sudlow G.P., Wiley H.S., Lauffenburger D.A. Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions. J. Biol. Chem. 269:1994;15749-15755.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15749-15755
-
-
French, A.R.1
Sudlow, G.P.2
Wiley, H.S.3
Lauffenburger, D.A.4
-
26
-
-
0033605560
-
ErbB2 amplification inhibits down-regulation and induces constitutive activation of both ErbB2 and epidermal growth factor receptors
-
Worthylake R., Opresko L.K., Wiley H.S. ErbB2 amplification inhibits down-regulation and induces constitutive activation of both ErbB2 and epidermal growth factor receptors. J. Biol. Chem. 274:1999;8865-8874.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8865-8874
-
-
Worthylake, R.1
Opresko, L.K.2
Wiley, H.S.3
-
27
-
-
0032577487
-
Alternative intracellular routing of ErbB receptors may determine signaling potency
-
Waterman H., Sabanai I., Geiger B., Yarden Y. Alternative intracellular routing of ErbB receptors may determine signaling potency. J. Biol. Chem. 273:1998;13819-13827.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13819-13827
-
-
Waterman, H.1
Sabanai, I.2
Geiger, B.3
Yarden, Y.4
-
28
-
-
0027382449
-
The carboxyl terminus of epidermal growth factor receptor/ErbB2 chimerae is internalization impaired
-
Sorkin A., Di Fiore P.P., Carpenter G. The carboxyl terminus of epidermal growth factor receptor/ErbB2 chimerae is internalization impaired. Oncogene. 8:1993;3021-3028.
-
(1993)
Oncogene
, vol.8
, pp. 3021-3028
-
-
Sorkin, A.1
Di Fiore, P.P.2
Carpenter, G.3
-
29
-
-
0033564877
-
The C-terminus of the kinase-defective neuregulin receptor ErbB3 confers mitogenic superiority and dictates endocytic routing
-
Waterman H., Alroy I., Strano S., Seger R., Yarden Y. The C-terminus of the kinase-defective neuregulin receptor ErbB3 confers mitogenic superiority and dictates endocytic routing. EMBO J. 18:1999;3348-3358.
-
(1999)
EMBO J.
, vol.18
, pp. 3348-3358
-
-
Waterman, H.1
Alroy, I.2
Strano, S.3
Seger, R.4
Yarden, Y.5
-
30
-
-
18444404925
-
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: Implications for cancer therapy
-
Citri A., Alroy I., Lavi S., Rubin C., Xu W., Grammatikakis N., Patterson C., Neckers L., Fry D.W., Yarden Y. Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases implications for cancer therapy . EMBO J. 21:2002;2407-2417.
-
(2002)
EMBO J.
, vol.21
, pp. 2407-2417
-
-
Citri, A.1
Alroy, I.2
Lavi, S.3
Rubin, C.4
Xu, W.5
Grammatikakis, N.6
Patterson, C.7
Neckers, L.8
Fry, D.W.9
Yarden, Y.10
-
31
-
-
0025219239
-
Differential processing and turnover of the oncogenically activated neu/erb B2 gene product and its normal cellular counterpart
-
Huang S.S., Koh H.A., Konish Y., Bullock L.D., Huang J.S. Differential processing and turnover of the oncogenically activated neu/erb B2 gene product and its normal cellular counterpart. J. Biol. Chem. 265:1990;3340-3346.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 3340-3346
-
-
Huang, S.S.1
Koh, H.A.2
Konish, Y.3
Bullock, L.D.4
Huang, J.S.5
-
32
-
-
0025971082
-
Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor
-
Sorkin A., Westermark B., Heldin C.H., Claesson-Welsh L. Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor. J. Cell Biol. 112:1991;469-478.
-
(1991)
J. Cell Biol.
, vol.112
, pp. 469-478
-
-
Sorkin, A.1
Westermark, B.2
Heldin, C.H.3
Claesson-Welsh, L.4
-
33
-
-
0024417285
-
Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation
-
Chen W.S., Lazar C.S., Lund K.A., Welsh J.B., Chang C.P., Walton G.M., Der C.J., Wiley H.S., Gill G.N., Rosenfeld M.G. Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59. 1989;33-43.
-
(1989)
Cell 59
, pp. 33-43
-
-
Chen, W.S.1
Lazar, C.S.2
Lund, K.A.3
Welsh, J.B.4
Chang, C.P.5
Walton, G.M.6
Der, C.J.7
Wiley, H.S.8
Gill, G.N.9
Rosenfeld, M.G.10
-
34
-
-
0026344988
-
Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor
-
Chang C.P., Kao J.P., Lazar C.S., Walsh B.J., Wells A., Wiley H.S., Gill G.N., Rosenfeld M.G. Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor. J. Biol. Chem. 266:1991;23467-23470.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 23467-23470
-
-
Chang, C.P.1
Kao, J.P.2
Lazar, C.S.3
Walsh, B.J.4
Wells, A.5
Wiley, H.S.6
Gill, G.N.7
Rosenfeld, M.G.8
-
35
-
-
0036341207
-
Signal transduction and endocytosis: Close encounters of many kinds
-
Sorkin A., Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nat. Rev. Mol. Cell. Biol. 3:2002;600-614.
-
(2002)
Nat. Rev. Mol. Cell. Biol.
, vol.3
, pp. 600-614
-
-
Sorkin, A.1
Von Zastrow, M.2
-
36
-
-
0033847398
-
EGF receptor residues leu(679), leu(680) mediate selective sorting of ligand-receptor complexes in early endosomal compartments
-
Kil S.J., Carlin C. EGF receptor residues leu(679), leu(680) mediate selective sorting of ligand-receptor complexes in early endosomal compartments. J. Cell Physiol. 185:2000;47-60.
-
(2000)
J. Cell Physiol.
, vol.185
, pp. 47-60
-
-
Kil, S.J.1
Carlin, C.2
-
37
-
-
0032217156
-
C-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
Levkowitz G., Waterman H., Zamir E., Kam Z., Oved S., Langdon W.Y., Beguinot L., Geiger B., Yarden Y. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev. 12:1998;3663-3674.
-
(1998)
Genes Dev.
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
Waterman, H.2
Zamir, E.3
Kam, Z.4
Oved, S.5
Langdon, W.Y.6
Beguinot, L.7
Geiger, B.8
Yarden, Y.9
-
38
-
-
0032893679
-
Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization
-
Torrisi M.R., Lotti L.V., Belleudi F., Gradini R., Salcini A.E., Confalonieri S., Pelicci P.G., Di Fiore P.P. Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization. Mol. Biol. Cell. 10:1999;417-434.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 417-434
-
-
Torrisi, M.R.1
Lotti, L.V.2
Belleudi, F.3
Gradini, R.4
Salcini, A.E.5
Confalonieri, S.6
Pelicci, P.G.7
Di Fiore, P.P.8
-
40
-
-
0032479444
-
Distinct saturable pathways for the endocytosis of different tyrosine motifs
-
Warren R.A., Green F.A., Stenberg P.E., Enns C.A. Distinct saturable pathways for the endocytosis of different tyrosine motifs. J. Biol. Chem. 273:1998;17056-17063.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17056-17063
-
-
Warren, R.A.1
Green, F.A.2
Stenberg, P.E.3
Enns, C.A.4
-
41
-
-
0345829921
-
Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GAP RN-tre
-
L. Martinu, A. Santiago-Walker, H. Qi, M.M. Chou, Endocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GAP RN-tre, J. Biol. Chem. 277 (2002) 50996-51002.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50996-51002
-
-
Martinu, L.1
Santiago-Walker, A.2
Qi, H.3
Chou, M.M.4
-
42
-
-
0036558279
-
Role of Grb2 in EGF-stimulated EGFR internalization
-
Yamazaki T., Zaal K., Hailey D., Presley J., Lippincott-Schwartz J., Samelson L.E. Role of Grb2 in EGF-stimulated EGFR internalization. J. Cell. Sci. 115:2002;1791-1802.
-
(2002)
J. Cell. Sci.
, vol.115
, pp. 1791-1802
-
-
Yamazaki, T.1
Zaal, K.2
Hailey, D.3
Presley, J.4
Lippincott-Schwartz, J.5
Samelson, L.E.6
-
43
-
-
0027203952
-
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors
-
Chang C.P., Lazar C.S., Walsh B.J., Komuro M., Collawn J.F., Kuhn L.A., Tainer J.A., Trowbridge I.S., Farquhar M.G., Rosenfeld M.G., Wiley H.S., Gill G.N. Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors. J. Biol. Chem. 268:1993;19312-19320.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19312-19320
-
-
Chang, C.P.1
Lazar, C.S.2
Walsh, B.J.3
Komuro, M.4
Collawn, J.F.5
Kuhn, L.A.6
Tainer, J.A.7
Trowbridge, I.S.8
Farquhar, M.G.9
Rosenfeld, M.G.10
Wiley, H.S.11
Gill, G.N.12
-
44
-
-
0025038705
-
Functional reconstitutional of the human epidermal growth factor receptor system in Xenopus oocytes
-
Opresko L.K., Wiley H.S. Functional reconstitutional of the human epidermal growth factor receptor system in Xenopus oocytes. J. Cell Biol. 111:1990;1661-1671.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 1661-1671
-
-
Opresko, L.K.1
Wiley, H.S.2
-
45
-
-
0029979181
-
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes
-
Futter C.E., Pearse A., Hewlett L.J., Hopkins C.R. Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J. Cell Biol. 132:1996;1011-1023.
-
(1996)
J. Cell Biol.
, vol.132
, pp. 1011-1023
-
-
Futter, C.E.1
Pearse, A.2
Hewlett, L.J.3
Hopkins, C.R.4
-
46
-
-
0035945343
-
Human VPS34 is required for internal vesicle formation within multivesicular endosomes
-
Futter C.E., Collinson L.M., Backer J.M., Hopkins C.R. Human VPS34 is required for internal vesicle formation within multivesicular endosomes. J. Cell Biol. 155:2001;1251-1264.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 1251-1264
-
-
Futter, C.E.1
Collinson, L.M.2
Backer, J.M.3
Hopkins, C.R.4
-
47
-
-
0035985198
-
Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway
-
Tebar F., Villalonga P., Sorkina T., Agell N., Sorkin A., Enrich C. Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway. Mol. Biol. Cell. 13:2002;2057-2068.
-
(2002)
Mol. Biol. Cell.
, vol.13
, pp. 2057-2068
-
-
Tebar, F.1
Villalonga, P.2
Sorkina, T.3
Agell, N.4
Sorkin, A.5
Enrich, C.6
-
48
-
-
0033790332
-
E3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes
-
Crooks D., Kil S.J., McCaffery J.M., Carlin C. E3-13.7 integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes. Mol. Biol. Cell. 11:2000;3559-3572.
-
(2000)
Mol. Biol. Cell.
, vol.11
, pp. 3559-3572
-
-
Crooks, D.1
Kil, S.J.2
McCaffery, J.M.3
Carlin, C.4
-
49
-
-
0029762883
-
Enhanced degradation of EGF receptors by a sorting nexin, SNX1
-
Kurten R.C., Cadena D.L., Gill G.N. Enhanced degradation of EGF receptors by a sorting nexin, SNX1. Science. 272:1996;1008-1010.
-
(1996)
Science
, vol.272
, pp. 1008-1010
-
-
Kurten, R.C.1
Cadena, D.L.2
Gill, G.N.3
-
50
-
-
0036080605
-
EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain
-
Jones S.M., Foreman S.K., Shank B.B., Kurten R.C. EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain. Am. J. Physiol. Cell. Physiol. 282:2002;C420-C433.
-
(2002)
Am. J. Physiol. Cell. Physiol.
, vol.282
-
-
Jones, S.M.1
Foreman, S.K.2
Shank, B.B.3
Kurten, R.C.4
-
51
-
-
0141599428
-
Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor
-
Stamos J., Sliwkowski M.X., Eigenbrot C. Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor. J. Biol. Chem. 277:2002;46265-46272.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 46265-46272
-
-
Stamos, J.1
Sliwkowski, M.X.2
Eigenbrot, C.3
-
52
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
-
Levkowitz G., Waterman H., Ettenberg S.A., Katz M., Tsygankov A.Y., Alroy I., Lavi S., Iwai K., Reiss Y., Ciechanover A., Lipkowitz S., Yarden Y. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Mol. Cell. 4:1999;1029-1040.
-
(1999)
Mol. Cell.
, vol.4
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
Lavi, S.7
Iwai, K.8
Reiss, Y.9
Ciechanover, A.10
Lipkowitz, S.11
Yarden, Y.12
-
53
-
-
0033615732
-
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7
-
Yokouchi M., Kondo T., Houghton A., Bartkiewicz M., Horne W.C., Zhang H., Yoshimura A., Baron R. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7. J. Biol. Chem. 274:1999;31707-31712.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31707-31712
-
-
Yokouchi, M.1
Kondo, T.2
Houghton, A.3
Bartkiewicz, M.4
Horne, W.C.5
Zhang, H.6
Yoshimura, A.7
Baron, R.8
-
54
-
-
0028920694
-
Sli-1, a negative regulator of let-23-mediated signaling in C. elegans
-
Jongeward G.D., Clandinin T.R., Sternberg P.W. sli-1, a negative regulator of let-23-mediated signaling in C. elegans. Genetics. 139:1995;1553-1566.
-
(1995)
Genetics
, vol.139
, pp. 1553-1566
-
-
Jongeward, G.D.1
Clandinin, T.R.2
Sternberg, P.W.3
-
55
-
-
0033523010
-
Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain
-
Miyake S., Mullane-Robinson K.P., Lill N.L., Douillard P., Band H. Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain. J. Biol. Chem. 274:1999;16619-16628.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16619-16628
-
-
Miyake, S.1
Mullane-Robinson, K.P.2
Lill, N.L.3
Douillard, P.4
Band, H.5
-
56
-
-
0033169024
-
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation
-
Lee P.S., Wang Y., Dominguez M.G., Yeung Y.G., Murphy M.A., Bowtell D.D., Stanley E.R. The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation. EMBO J. 18:1999;3616-3628.
-
(1999)
EMBO J.
, vol.18
, pp. 3616-3628
-
-
Lee, P.S.1
Wang, Y.2
Dominguez, M.G.3
Yeung, Y.G.4
Murphy, M.A.5
Bowtell, D.D.6
Stanley, E.R.7
-
57
-
-
0029917264
-
Coupling of the c-Cbl protooncogene product to ErbB1/EGF-receptor but not to other ErbB proteins
-
Levkowitz G., Klapper L.N., Tzahar E., Freywald A., Sela M., Yarden Y. Coupling of the c-Cbl protooncogene product to ErbB1/EGF-receptor but not to other ErbB proteins. Oncogene. 12:1996;1117-1125.
-
(1996)
Oncogene
, vol.12
, pp. 1117-1125
-
-
Levkowitz, G.1
Klapper, L.N.2
Tzahar, E.3
Freywald, A.4
Sela, M.5
Yarden, Y.6
-
58
-
-
0032860819
-
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers
-
Muthuswamy S.K., Gilman M., Brugge J.S. Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers. Mol. Cell. Biol. 19:1999;6845-6857.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6845-6857
-
-
Muthuswamy, S.K.1
Gilman, M.2
Brugge, J.S.3
-
59
-
-
0034234854
-
Tumor-inhibitory antibodies to HER-2/ErbB2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
-
Klapper L.N., Waterman H., Sela M., Yarden Y. Tumor-inhibitory antibodies to HER-2/ErbB2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res. 60:2000;3384-3388.
-
(2000)
Cancer Res.
, vol.60
, pp. 3384-3388
-
-
Klapper, L.N.1
Waterman, H.2
Sela, M.3
Yarden, Y.4
-
60
-
-
0000414462
-
Leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes
-
Kil S.J., Hobert M., Carlin C.A. leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand-receptor complexes to lysosomes. J. Biol. Chem. 274:1999;3141-3150.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3141-3150
-
-
Kil, S.J.1
Hobert, M.2
Carlin, C.A.3
-
61
-
-
0031858649
-
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice
-
Murphy M.A., Schnall R.G., Venter D.J., Barnett L., Bertoncello I., Thien C.B., Langdon W.Y., Bowtell D.D. Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice. Mol. Cell. Biol. 18:1998;4872-4882.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4872-4882
-
-
Murphy, M.A.1
Schnall, R.G.2
Venter, D.J.3
Barnett, L.4
Bertoncello, I.5
Thien, C.B.6
Langdon, W.Y.7
Bowtell, D.D.8
-
62
-
-
0035958546
-
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
-
Katzmann D.J., Babst M., Emr S.D. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell. 106:2001;145-155.
-
(2001)
Cell
, vol.106
, pp. 145-155
-
-
Katzmann, D.J.1
Babst, M.2
Emr, S.D.3
-
63
-
-
0037119950
-
Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
-
Wong E.S., Fong C.W., Lim J., Yusoff P., Low B.C., Langdon W.Y., Guy G.R. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling. EMBO J. 21:2002;4796-4808.
-
(2002)
EMBO J.
, vol.21
, pp. 4796-4808
-
-
Wong, E.S.1
Fong, C.W.2
Lim, J.3
Yusoff, P.4
Low, B.C.5
Langdon, W.Y.6
Guy, G.R.7
-
64
-
-
0037075547
-
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
-
Soubeyran P., Kowanetz K., Szymkiewicz I., Langdon W.Y., Dikic I. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature. 416:2002;183-187.
-
(2002)
Nature
, vol.416
, pp. 183-187
-
-
Soubeyran, P.1
Kowanetz, K.2
Szymkiewicz, I.3
Langdon, W.Y.4
Dikic, I.5
-
65
-
-
0023840804
-
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies
-
Glenney J.R. Jr., Chen W.S., Lazar C.S., Walton G.M., Zokas L.M., Rosenfeld M.G., Gill G.N. Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell. 52:1988;675-684.
-
(1988)
Cell
, vol.52
, pp. 675-684
-
-
Glenney J.R., Jr.1
Chen, W.S.2
Lazar, C.S.3
Walton, G.M.4
Zokas, L.M.5
Rosenfeld, M.G.6
Gill, G.N.7
-
66
-
-
0018581544
-
Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor
-
Haigler H.T., McKanna J.A., Cohen S. Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J. Cell Biol. 83:1979;82-90.
-
(1979)
J. Cell Biol.
, vol.83
, pp. 82-90
-
-
Haigler, H.T.1
McKanna, J.A.2
Cohen, S.3
-
67
-
-
0020366345
-
Epidermal growth factor stimulates fluid phase endocytosis in human fibroblasts through a signal generated at the cell surface
-
Wiley H.S., Cunningham D.D. Epidermal growth factor stimulates fluid phase endocytosis in human fibroblasts through a signal generated at the cell surface. J. Cell Biochem. 19:1982;383-394.
-
(1982)
J. Cell Biochem.
, vol.19
, pp. 383-394
-
-
Wiley, H.S.1
Cunningham, D.D.2
-
68
-
-
0023677140
-
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system
-
Wiley H.S. Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J. Cell Biol. 107:1988;801-810.
-
(1988)
J. Cell Biol.
, vol.107
, pp. 801-810
-
-
Wiley, H.S.1
-
69
-
-
0021689229
-
Epidermal growth factor rapidly induces a redistribution of transferrin receptor pools in human fibroblasts
-
Wiley H.S., Kaplan J. Epidermal growth factor rapidly induces a redistribution of transferrin receptor pools in human fibroblasts. Proc. Natl. Acad. Sci. USA. 81:1984;7456-7460.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 7456-7460
-
-
Wiley, H.S.1
Kaplan, J.2
-
70
-
-
0032482379
-
EGF induces recycling membrane to form ruffles
-
Bretscher M.S., Aguado-Velasco C. EGF induces recycling membrane to form ruffles. Curr. Biol. 8:1998;721-724.
-
(1998)
Curr. Biol.
, vol.8
, pp. 721-724
-
-
Bretscher, M.S.1
Aguado-Velasco, C.2
-
71
-
-
0024836461
-
Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells
-
West M.A., Bretscher M.S., Watts C. Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells. J. Cell Biol. 109:1989;2731-2739.
-
(1989)
J. Cell Biol.
, vol.109
, pp. 2731-2739
-
-
West, M.A.1
Bretscher, M.S.2
Watts, C.3
-
72
-
-
0021803670
-
Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions
-
Wiley H.S., VanNostrand W., McKinley D.N., Cunningham D.D. Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions. J. Biol. Chem. 260:1985;5290-5295.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 5290-5295
-
-
Wiley, H.S.1
VanNostrand, W.2
McKinley, D.N.3
Cunningham, D.D.4
-
73
-
-
0027965262
-
Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
-
Di Guglielmo G.M., Baass P.C., Ou W.J., Posner B.I., Bergeron J.J. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13:1994;4269-4277.
-
(1994)
EMBO J.
, vol.13
, pp. 4269-4277
-
-
Di Guglielmo, G.M.1
Baass, P.C.2
Ou, W.J.3
Posner, B.I.4
Bergeron, J.J.5
-
74
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer P., Hunter T., Lindberg R.A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10:1994;251-337.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 251-337
-
-
Van der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
75
-
-
0026612457
-
Intracellular localization of the P21rho proteins
-
Adamson P., Paterson H.F., Hall A. Intracellular localization of the P21rho proteins. J. Cell Biol. 119:1992;617-627.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 617-627
-
-
Adamson, P.1
Paterson, H.F.2
Hall, A.3
-
76
-
-
0026611047
-
Association of p60c-src with endosomal membranes in mammalian fibroblasts
-
Kaplan K.B., Swedlow J.R., Varmus H.E., Morgan D.O. Association of p60c-src with endosomal membranes in mammalian fibroblasts. J. Cell Biol. 118:1992;321-333.
-
(1992)
J. Cell Biol.
, vol.118
, pp. 321-333
-
-
Kaplan, K.B.1
Swedlow, J.R.2
Varmus, H.E.3
Morgan, D.O.4
-
77
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira A.V., Lamaze C., Schmid S.L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science. 274:1996;2086-2089.
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
78
-
-
0033555946
-
Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
-
Ahn S., Maudsley S., Luttrell L.M., Lefkowitz R.J., Daaka Y. Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J. Biol. Chem. 274:1999;1185-1188.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1185-1188
-
-
Ahn, S.1
Maudsley, S.2
Luttrell, L.M.3
Lefkowitz, R.J.4
Daaka, Y.5
-
79
-
-
0031975838
-
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
-
Daaka Y., Luttrell L.M., Ahn S., Della Rocca G.J., Ferguson S.S., Caron M.G., Lefkowitz R.J. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J. Biol. Chem. 273:1998;685-688.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 685-688
-
-
Daaka, Y.1
Luttrell, L.M.2
Ahn, S.3
Della Rocca, G.J.4
Ferguson, S.S.5
Caron, M.G.6
Lefkowitz, R.J.7
-
81
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
Huang H.S., Nagane M., Klingbeil C.K., Lin H., Nishikawa R., Ji X.D., Huang C.M., Gill G.N., Wiley H.S., Cavenee W.K. The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J. Biol. Chem. 272:1997;2927-2935.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2927-2935
-
-
Huang, H.S.1
Nagane, M.2
Klingbeil, C.K.3
Lin, H.4
Nishikawa, R.5
Ji, X.D.6
Huang, C.M.7
Gill, G.N.8
Wiley, H.S.9
Cavenee, W.K.10
-
82
-
-
0025139326
-
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
-
Wells A., Welsh J.B., Lazar C.S., Wiley H.S., Gill G.N., Rosenfeld M.G. Ligand-induced transformation by a noninternalizing epidermal growth factor receptor. Science. 247:1990;962-964.
-
(1990)
Science
, vol.247
, pp. 962-964
-
-
Wells, A.1
Welsh, J.B.2
Lazar, C.S.3
Wiley, H.S.4
Gill, G.N.5
Rosenfeld, M.G.6
-
83
-
-
0033607542
-
Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts
-
Haugh J.M., Huang A.C., Wiley H.S., Wells A., Lauffenburger D.A. Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts. J. Biol. Chem. 274:1999;34350-34360.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34350-34360
-
-
Haugh, J.M.1
Huang, A.C.2
Wiley, H.S.3
Wells, A.4
Lauffenburger, D.A.5
-
84
-
-
0037081644
-
Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes: Implications for phospholipase C and PI3-kinase signaling
-
Haugh J.M., Meyer T. Active EGF receptors have limited access to PtdIns(4,5)P(2) in endosomes implications for phospholipase C and PI3-kinase signaling . J. Cell. Sci. 115:2002;303-310.
-
(2002)
J. Cell. Sci.
, vol.115
, pp. 303-310
-
-
Haugh, J.M.1
Meyer, T.2
-
85
-
-
0026519802
-
Surface expression of ErbB2 protein is post-transcriptionally regulated in mammary epithelial cells by epidermal growth factor and by the culture density
-
Kornilova E.S., Taverna D., Hoeck W., Hynes N.E. Surface expression of ErbB2 protein is post-transcriptionally regulated in mammary epithelial cells by epidermal growth factor and by the culture density. Oncogene. 7:1992;511-519.
-
(1992)
Oncogene
, vol.7
, pp. 511-519
-
-
Kornilova, E.S.1
Taverna, D.2
Hoeck, W.3
Hynes, N.E.4
-
86
-
-
0024023873
-
EGF binding to its receptor triggers a rapid tyrosine phosphorylation of the ErbB2 protein in the mammary tumor cell line SK-BR-3
-
King C.R., Borrello I., Bellot F., Comoglio P., Schlessinger J. EGF binding to its receptor triggers a rapid tyrosine phosphorylation of the ErbB2 protein in the mammary tumor cell line SK-BR-3. EMBO J. 7:1988;1647-1651.
-
(1988)
EMBO J.
, vol.7
, pp. 1647-1651
-
-
King, C.R.1
Borrello, I.2
Bellot, F.3
Comoglio, P.4
Schlessinger, J.5
-
87
-
-
0030968648
-
Structural aspects of the epidermal growth factor receptor required for transmodulation of ErbB2/neu
-
Worthylake R., Wiley H.S. Structural aspects of the epidermal growth factor receptor required for transmodulation of ErbB2/neu. J. Biol. Chem. 272:1997;8594-8601.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8594-8601
-
-
Worthylake, R.1
Wiley, H.S.2
-
88
-
-
0033534480
-
A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2
-
Schaefer G., Akita R.W., Sliwkowski M.X. A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2. J. Biol. Chem. 274:1999;859-866.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 859-866
-
-
Schaefer, G.1
Akita, R.W.2
Sliwkowski, M.X.3
-
89
-
-
0344713844
-
A quantitative model of the effects of HER2 expression on EGFR and HER2 levels and trafficking
-
In press
-
Hendriks B.S., Opresko L.K., Wiley H.S., Lauffenburger D.A. A quantitative model of the effects of HER2 expression on EGFR and HER2 levels and trafficking. Cancer Res. (2003) (In press).
-
(2003)
Cancer Res.
-
-
Hendriks, B.S.1
Opresko, L.K.2
Wiley, H.S.3
Lauffenburger, D.A.4
-
90
-
-
0029968917
-
Expression of epidermal growth factor and its receptor in normal and diseased human kidney: An immunohistochemical and in situ hybridization study
-
Gesualdo L., Di Paolo S., Calabro A., Milani S., Maiorano E., Ranieri E., Pannarale G., Schena F.P. Expression of epidermal growth factor and its receptor in normal and diseased human kidney: an immunohistochemical and in situ hybridization study. Kidney Int. 49:1996;656-665.
-
(1996)
Kidney Int.
, vol.49
, pp. 656-665
-
-
Gesualdo, L.1
Di Paolo, S.2
Calabro, A.3
Milani, S.4
Maiorano, E.5
Ranieri, E.6
Pannarale, G.7
Schena, F.P.8
-
91
-
-
0033584999
-
ErbB2 and ErbB3 receptors mediate inhibition of calcium-dependent chloride secretion in colonic epithelial cells
-
Keely S.J., Barrett K.E. ErbB2 and ErbB3 receptors mediate inhibition of calcium-dependent chloride secretion in colonic epithelial cells. J. Biol. Chem. 274:1999;33449-33454.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33449-33454
-
-
Keely, S.J.1
Barrett, K.E.2
-
92
-
-
0029839897
-
The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract
-
Playford R.J., Hanby A.M., Gschmeissner S., Peiffer L.P., Wright N.A., McGarrity T. The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract. Gut. 39:1996;262-266.
-
(1996)
Gut
, vol.39
, pp. 262-266
-
-
Playford, R.J.1
Hanby, A.M.2
Gschmeissner, S.3
Peiffer, L.P.4
Wright, N.A.5
McGarrity, T.6
-
93
-
-
0030857115
-
Apical enrichment of human EGF precursor in Madin-Darby canine kidney cells involves preferential basolateral ectodomain cleavage sensitive to a metalloprotease inhibitor
-
Dempsey P.J., Meise K.S., Yoshitake Y., Nishikawa K., Coffey R.J. Apical enrichment of human EGF precursor in Madin-Darby canine kidney cells involves preferential basolateral ectodomain cleavage sensitive to a metalloprotease inhibitor. J. Cell Biol. 138:1997;747-758.
-
(1997)
J. Cell Biol.
, vol.138
, pp. 747-758
-
-
Dempsey, P.J.1
Meise, K.S.2
Yoshitake, Y.3
Nishikawa, K.4
Coffey, R.J.5
-
94
-
-
0029082997
-
Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD
-
Du J., Wilson P.D. Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD. Am. J. Physiol. 269:1995;C487-C495.
-
(1995)
Am. J. Physiol.
, vol.269
-
-
Du, J.1
Wilson, P.D.2
-
95
-
-
0029993728
-
LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction
-
Simske J.S., Kaech S.M., Harp S.A., Kim S.K. LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction. Cell. 85:1996;195-204.
-
(1996)
Cell
, vol.85
, pp. 195-204
-
-
Simske, J.S.1
Kaech, S.M.2
Harp, S.A.3
Kim, S.K.4
-
96
-
-
0344731071
-
Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10
-
Whitfield C.W., Benard C., Barnes T., Hekimi S., Kim S.K. Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10. Mol. Biol. Cell. 10:1999;2087-2100.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 2087-2100
-
-
Whitfield, C.W.1
Benard, C.2
Barnes, T.3
Hekimi, S.4
Kim, S.K.5
-
97
-
-
0037064048
-
The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core
-
He C., Hobert M., Friend L., Carlin C. The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core. J. Biol. Chem. 277:2002;38284-38293.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38284-38293
-
-
He, C.1
Hobert, M.2
Friend, L.3
Carlin, C.4
-
98
-
-
0036723653
-
Basolateral targeting of ERBB2 is dependent on a novel bipartite juxtamembrane sorting signal but independent of the C-terminal ERBIN-binding domain
-
Dillon C., Creer A., Kerr K., Kumin A., Dickson C. Basolateral targeting of ERBB2 is dependent on a novel bipartite juxtamembrane sorting signal but independent of the C-terminal ERBIN-binding domain. Mol. Cell. Biol. 22:2002;6553-6563.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6553-6563
-
-
Dillon, C.1
Creer, A.2
Kerr, K.3
Kumin, A.4
Dickson, C.5
-
99
-
-
0025913730
-
Polarized distribution of bradykinin receptors on airway epithelial cells and independent coupling to second messenger pathways
-
Denning G.M., Welsh M.J. Polarized distribution of bradykinin receptors on airway epithelial cells and independent coupling to second messenger pathways. J. Biol. Chem. 266:1991;12932-12938.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12932-12938
-
-
Denning, G.M.1
Welsh, M.J.2
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