A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

EMBO Journal

Volumn 21, Issue 3, 2002, Pages 303-313

  Waterman, Hadassa ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Growth factor; SH2 domain; Signal transduction; Tyrosine kinase; Ubiquitin ligase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LIGASE; MUTANT PROTEIN; PROTEIN TYROSINE KINASE; UBIQUITIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME BINDING; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REACTION ANALYSIS; RECYCLING; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; ENDOCYTOSIS; GRB2 ADAPTOR PROTEIN; HUMANS; MUTATION; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL; RABBITS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

ANIMALIA;

EID: 0036469898     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.3.303     Document Type: Article

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