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Volumn 79, Issue , 2014, Pages 172-183

Engineering strategies to mimic the glioblastoma microenvironment

Author keywords

Biomaterials; Extracellular matrix; Glioblastoma; Invasion; Microenvironment; Motility; Tumor engineering

Indexed keywords

BIOMATERIALS; BLOOD VESSELS; CELLS; CYTOLOGY; SCAFFOLDS (BIOLOGY); TUMORS;

EID: 84919650367     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.08.012     Document Type: Review
Times cited : (117)

References (189)
  • 1
    • 84872612974 scopus 로고    scopus 로고
    • Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies
    • Agnihotri S., Burrell K.E., Wolf A., Jalali S., Hawkins C., et al. Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies. Arch. Immunol. Ther. Exp. 2013, 61:25-41. 10.1007/s00005-012-0203-0.
    • (2013) Arch. Immunol. Ther. Exp. , vol.61 , pp. 25-41
    • Agnihotri, S.1    Burrell, K.E.2    Wolf, A.3    Jalali, S.4    Hawkins, C.5
  • 2
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis D.N., Ohgaki H., Wiestler O.D., Cavenee W.K., Burger P.C., et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007, 114:97-109. 10.1007/s00401-007-0243-4.
    • (2007) Acta Neuropathol. , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3    Cavenee, W.K.4    Burger, P.C.5
  • 3
    • 84872609765 scopus 로고
    • Removal of right cerebral hemisphere for certain tumors with hemiplegia: Preliminary report
    • Dandy W.E. Removal of right cerebral hemisphere for certain tumors with hemiplegia: Preliminary report. JAMA 1928, 90:823-825. 10.1001/jama.1928.02690380007003.
    • (1928) JAMA , vol.90 , pp. 823-825
    • Dandy, W.E.1
  • 4
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R., Mason W.P., van den Bent M.J., Weller M., Fisher B., et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352:987-996. 10.1056/NEJMoa043330.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3    Weller, M.4    Fisher, B.5
  • 5
    • 0033171035 scopus 로고    scopus 로고
    • ". . .Those left behind". Biology and oncology of invasive glioma cells
    • Berens M.E., Giese A. ". . .Those left behind". Biology and oncology of invasive glioma cells. Neoplasia 1999, 1:208-219.
    • (1999) Neoplasia , vol.1 , pp. 208-219
    • Berens, M.E.1    Giese, A.2
  • 6
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • McLendon R., Friedman A., Bigner D., Meir E.G.V., Brat D.J., et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008, 455:1061-1068. 10.1038/nature07385.
    • (2008) Nature , vol.455 , pp. 1061-1068
    • McLendon, R.1    Friedman, A.2    Bigner, D.3    Meir, E.G.V.4    Brat, D.J.5
  • 7
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak R.G.W., Hoadley K.A., Purdom E., Wang V., Qi Y., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17:98-110. 10.1016/j.ccr.2009.12.020.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5
  • 8
    • 53449085011 scopus 로고    scopus 로고
    • Glioblastoma and stem cells
    • Altaner C. Glioblastoma and stem cells. Neoplasma 2008, 55:369-374.
    • (2008) Neoplasma , vol.55 , pp. 369-374
    • Altaner, C.1
  • 9
    • 33846531356 scopus 로고    scopus 로고
    • The tumour microenvironment as a target for chemoprevention
    • Albini A., Sporn M.B. The tumour microenvironment as a target for chemoprevention. Nat. Rev. Cancer 2007, 7:139-147. 10.1038/nrc2067.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 139-147
    • Albini, A.1    Sporn, M.B.2
  • 10
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce J.A., Pollard J.W. Microenvironmental regulation of metastasis. Nat. Rev. Cancer 2009, 9:239-252. 10.1038/nrc2618.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 12
    • 79958210803 scopus 로고    scopus 로고
    • AVAglio: phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme
    • Chinot O.L., de LM Rouge T., Moore N., Zeaiter A., Das A., et al. AVAglio: phase 3 trial of bevacizumab plus temozolomide and radiotherapy in newly diagnosed glioblastoma multiforme. Adv. Ther. 2011, 28:334-340. 10.1007/s12325-011-0007-3.
    • (2011) Adv. Ther. , vol.28 , pp. 334-340
    • Chinot, O.L.1    de LM, R.T.2    Moore, N.3    Zeaiter, A.4    Das, A.5
  • 13
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • Kreisl T.N., Kim L., Moore K., Duic P., Royce C., et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J. Clin. Oncol. 2009, 27:740-745. 10.1200/JCO.2008.16.3055.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 740-745
    • Kreisl, T.N.1    Kim, L.2    Moore, K.3    Duic, P.4    Royce, C.5
  • 14
    • 84856806386 scopus 로고    scopus 로고
    • A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma: clinical article
    • Narayana A., Gruber D., Kunnakkat S., Golfinos J.G., Parker E., et al. A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma: clinical article. J. Neurosurg. 2012, 116:341-345. 10.3171/2011.9.JNS11656.
    • (2012) J. Neurosurg. , vol.116 , pp. 341-345
    • Narayana, A.1    Gruber, D.2    Kunnakkat, S.3    Golfinos, J.G.4    Parker, E.5
  • 15
    • 33947191055 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
    • Vredenburgh J.J., Desjardins A., Herndon J.E., Dowell J.M., Reardon D.A., et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin. Cancer Res. 2007, 13:1253-1259. 10.1158/1078-0432.CCR-06-2309.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1253-1259
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon, J.E.3    Dowell, J.M.4    Reardon, D.A.5
  • 16
    • 84894449285 scopus 로고    scopus 로고
    • Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres
    • Jain A., Betancur M., Patel G.D., Valmikinathan C.M., Mukhatyar V.J., et al. Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres. Nat. Mater. 2014, 13:308-316. 10.1038/nmat3878.
    • (2014) Nat. Mater. , vol.13 , pp. 308-316
    • Jain, A.1    Betancur, M.2    Patel, G.D.3    Valmikinathan, C.M.4    Mukhatyar, V.J.5
  • 18
    • 84886443619 scopus 로고    scopus 로고
    • The pathobiology of collagens in glioma
    • Payne L.S., Huang P. The pathobiology of collagens in glioma. Mol. Cancer Res. 2013, 11(10):1129-1140.
    • (2013) Mol. Cancer Res. , vol.11 , Issue.10 , pp. 1129-1140
    • Payne, L.S.1    Huang, P.2
  • 19
    • 84919652857 scopus 로고    scopus 로고
    • Mechanobiology in health and disease in the central nervous system
    • CRC Press, (Available: . Accessed 14 August 2013), J. Nagatomi (Ed.)
    • Ulrich T., Kumar S. Mechanobiology in health and disease in the central nervous system. Mechanobiology handbook 2011, 391-411. CRC Press, (Available: http://www.crcnetbase.com/doi/abs/10.1201/b10780-23. Accessed 14 August 2013). J. Nagatomi (Ed.).
    • (2011) Mechanobiology handbook , pp. 391-411
    • Ulrich, T.1    Kumar, S.2
  • 21
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 2004, 4:528-539. 10.1038/nrc1391.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 22
    • 0027273913 scopus 로고
    • Hyaluronan and hyaluronectin in the extracellular matrix of human brain tumour stroma
    • Delpech B., Maingonnat C., Girard N., Chauzy C., Maunoury R., et al. Hyaluronan and hyaluronectin in the extracellular matrix of human brain tumour stroma. Eur. J. Cancer 1993, 29A:1012-1017.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 1012-1017
    • Delpech, B.1    Maingonnat, C.2    Girard, N.3    Chauzy, C.4    Maunoury, R.5
  • 23
    • 77954449068 scopus 로고    scopus 로고
    • Modulation of hyaluronan production by CD44 positive glioma cells
    • Wiranowska M., Ladd S., Moscinski L.C., Hill B., Haller E., et al. Modulation of hyaluronan production by CD44 positive glioma cells. Int. J. Cancer 2010, 127:532-542. 10.1002/ijc.25085.
    • (2010) Int. J. Cancer , vol.127 , pp. 532-542
    • Wiranowska, M.1    Ladd, S.2    Moscinski, L.C.3    Hill, B.4    Haller, E.5
  • 24
    • 0029164722 scopus 로고
    • Role of CD44 in the invasiveness of glioblastoma multiforme and the noninvasiveness of meningioma: an immunohistochemistry study
    • Ariza A., López D., Mate J.L., Isamat M., Musulén E., et al. Role of CD44 in the invasiveness of glioblastoma multiforme and the noninvasiveness of meningioma: an immunohistochemistry study. Hum. Pathol. 1995, 26:1144-1147.
    • (1995) Hum. Pathol. , vol.26 , pp. 1144-1147
    • Ariza, A.1    López, D.2    Mate, J.L.3    Isamat, M.4    Musulén, E.5
  • 25
    • 35448988125 scopus 로고    scopus 로고
    • CD44 adhesion molecule and neuro-glial proteoglycan NG2 as invasive markers of glioma
    • Wiranowska M., Ladd S., Smith S.R., Gottschall P.E. CD44 adhesion molecule and neuro-glial proteoglycan NG2 as invasive markers of glioma. Brain Cell Biol. 2006, 35:159-172. 10.1007/s11068-007-9009-0.
    • (2006) Brain Cell Biol. , vol.35 , pp. 159-172
    • Wiranowska, M.1    Ladd, S.2    Smith, S.R.3    Gottschall, P.E.4
  • 26
    • 44749091776 scopus 로고    scopus 로고
    • Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression
    • Bourguignon L.Y.W. Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression. Semin. Cancer Biol. 2008, 18:251-259. 10.1016/j.semcancer.2008.03.007.
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 251-259
    • Bourguignon, L.Y.W.1
  • 27
    • 0034695446 scopus 로고    scopus 로고
    • CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration
    • Bourguignon L.Y., Zhu H., Shao L., Chen Y.W. CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration. J. Biol. Chem. 2000, 275:1829-1838.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1829-1838
    • Bourguignon, L.Y.1    Zhu, H.2    Shao, L.3    Chen, Y.W.4
  • 28
    • 80052074643 scopus 로고    scopus 로고
    • CD44 signaling via PI3K/AKT and MAPK/ERK pathways protects CLL cells from spontaneous and drug induced apoptosis through MCL-1
    • Herishanu Y., Gibellini F., Njuguna N., Hazan-Halevy I., Keyvanfar K., et al. CD44 signaling via PI3K/AKT and MAPK/ERK pathways protects CLL cells from spontaneous and drug induced apoptosis through MCL-1. Leuk. Lymphoma 2011, 52:1758-1769. 10.3109/10428194.2011.569962.
    • (2011) Leuk. Lymphoma , vol.52 , pp. 1758-1769
    • Herishanu, Y.1    Gibellini, F.2    Njuguna, N.3    Hazan-Halevy, I.4    Keyvanfar, K.5
  • 29
    • 0033572449 scopus 로고    scopus 로고
    • Hyaluronidase-2 overexpression accelerates intracerebral but not subcutaneous tumor formation of murine astrocytoma cells
    • Novak U., Stylli S.S., Kaye A.H., Lepperdinger G. Hyaluronidase-2 overexpression accelerates intracerebral but not subcutaneous tumor formation of murine astrocytoma cells. Cancer Res. 1999, 59:6246-6250.
    • (1999) Cancer Res. , vol.59 , pp. 6246-6250
    • Novak, U.1    Stylli, S.S.2    Kaye, A.H.3    Lepperdinger, G.4
  • 30
    • 0029995767 scopus 로고    scopus 로고
    • Glioma invasion in the central nervous system
    • (discussion 250-252)
    • Giese A., Westphal M. Glioma invasion in the central nervous system. Neurosurgery 1996, 39:235-250. (discussion 250-252).
    • (1996) Neurosurgery , vol.39 , pp. 235-250
    • Giese, A.1    Westphal, M.2
  • 31
  • 32
  • 33
    • 9044246674 scopus 로고    scopus 로고
    • Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro
    • Yamamoto M., Mohanam S., Sawaya R., Fuller G.N., Seiki M., et al. Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res. 1996, 56:384-392.
    • (1996) Cancer Res. , vol.56 , pp. 384-392
    • Yamamoto, M.1    Mohanam, S.2    Sawaya, R.3    Fuller, G.N.4    Seiki, M.5
  • 34
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • Demuth T., Berens M.E. Molecular mechanisms of glioma cell migration and invasion. J. Neurooncol. 2004, 70:217-228. 10.1007/s11060-004-2751-6.
    • (2004) J. Neurooncol. , vol.70 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 35
    • 23244437028 scopus 로고    scopus 로고
    • Glioma expansion in collagen I matrices: analyzing collagen concentration-dependent growth and motility patterns
    • Kaufman L.J., Brangwynne C.P., Kasza K.E., Filippidi E., Gordon V.D., et al. Glioma expansion in collagen I matrices: analyzing collagen concentration-dependent growth and motility patterns. Biophys. J. 2005, 89:635-650. 10.1529/biophysj.105.061994.
    • (2005) Biophys. J. , vol.89 , pp. 635-650
    • Kaufman, L.J.1    Brangwynne, C.P.2    Kasza, K.E.3    Filippidi, E.4    Gordon, V.D.5
  • 36
    • 35248886076 scopus 로고    scopus 로고
    • Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: Evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin
    • Kawataki T., Yamane T., Naganuma H., Rousselle P., Andurén I., et al. Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: Evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin. Exp. Cell Res. 2007, 313:3819-3831. 10.1016/j.yexcr.2007.07.038.
    • (2007) Exp. Cell Res. , vol.313 , pp. 3819-3831
    • Kawataki, T.1    Yamane, T.2    Naganuma, H.3    Rousselle, P.4    Andurén, I.5
  • 37
    • 84871949179 scopus 로고    scopus 로고
    • Laminin alpha 2 enables glioblastoma stem cell growth
    • Lathia J.D., Li M., Hall P.E., Gallagher J., Hale J.S., et al. Laminin alpha 2 enables glioblastoma stem cell growth. Ann. Neurol. 2012, 72:766-778. 10.1002/ana.23674.
    • (2012) Ann. Neurol. , vol.72 , pp. 766-778
    • Lathia, J.D.1    Li, M.2    Hall, P.E.3    Gallagher, J.4    Hale, J.S.5
  • 38
    • 0032414023 scopus 로고    scopus 로고
    • Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues
    • Ohnishi T., Hiraga S., Izumoto S., Matsumura H., Kanemura Y., et al. Role of fibronectin-stimulated tumor cell migration in glioma invasion in vivo: clinical significance of fibronectin and fibronectin receptor expressed in human glioma tissues. Clin. Exp. Metastasis 1998, 16:729-741.
    • (1998) Clin. Exp. Metastasis , vol.16 , pp. 729-741
    • Ohnishi, T.1    Hiraga, S.2    Izumoto, S.3    Matsumura, H.4    Kanemura, Y.5
  • 39
    • 0037208857 scopus 로고    scopus 로고
    • Expression of extracellular matrix components in a highly infiltrative in vivo glioma model
    • Mahesparan R., Read T.-A., Lund-Johansen M., Skaftnesmo K.O., Bjerkvig R., et al. Expression of extracellular matrix components in a highly infiltrative in vivo glioma model. Acta Neuropathol. 2003, 105:49-57. 10.1007/s00401-002-0610-0.
    • (2003) Acta Neuropathol. , vol.105 , pp. 49-57
    • Mahesparan, R.1    Read, T.-A.2    Lund-Johansen, M.3    Skaftnesmo, K.O.4    Bjerkvig, R.5
  • 41
    • 33845329178 scopus 로고    scopus 로고
    • Signalling via integrins: implications for cell survival and anticancer strategies
    • Hehlgans S., Haase M., Cordes N. Signalling via integrins: implications for cell survival and anticancer strategies. Biochim. Biophys. Acta 2007, 1775:163-180. 10.1016/j.bbcan.2006.09.001.
    • (2007) Biochim. Biophys. Acta , vol.1775 , pp. 163-180
    • Hehlgans, S.1    Haase, M.2    Cordes, N.3
  • 42
    • 0035899331 scopus 로고    scopus 로고
    • Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
    • Aoudjit F., Vuori K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 2001, 20:4995-5004. 10.1038/sj.onc.1204554.
    • (2001) Oncogene , vol.20 , pp. 4995-5004
    • Aoudjit, F.1    Vuori, K.2
  • 44
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: regulators of the tumor microenvironment
    • Kessenbrock K., Plaks V., Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010, 141:52-67. 10.1016/j.cell.2010.03.015.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 45
    • 0041737535 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma invasiveness: the role of proteases
    • Rao J.S. Molecular mechanisms of glioma invasiveness: the role of proteases. Nat. Rev. Cancer 2003, 3:489-501. 10.1038/nrc1121.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 489-501
    • Rao, J.S.1
  • 46
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher D.E., Janmey P., Wang Y. Tissue cells feel and respond to the stiffness of their substrate. Science 2005, 310:1139-1143. 10.1126/science.1116995.
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.3
  • 47
    • 84859387007 scopus 로고    scopus 로고
    • Tension is required but not sufficient for focal adhesion maturation without a stress fiber template
    • Oakes P.W., Beckham Y., Stricker J., Gardel M.L. Tension is required but not sufficient for focal adhesion maturation without a stress fiber template. J. Cell Biol. 2012, 196:363-374. 10.1083/jcb.201107042.
    • (2012) J. Cell Biol. , vol.196 , pp. 363-374
    • Oakes, P.W.1    Beckham, Y.2    Stricker, J.3    Gardel, M.L.4
  • 48
    • 0025873299 scopus 로고
    • The role of solation-contraction coupling in regulating stress fiber dynamics in nonmuscle cells
    • Kolega J., Janson L.W., Taylor D.L. The role of solation-contraction coupling in regulating stress fiber dynamics in nonmuscle cells. J. Cell Biol. 1991, 114:993-1003.
    • (1991) J. Cell Biol. , vol.114 , pp. 993-1003
    • Kolega, J.1    Janson, L.W.2    Taylor, D.L.3
  • 49
    • 84880673342 scopus 로고    scopus 로고
    • Vinculin tension distributions of individual stress fibers within cell-matrix adhesions
    • Chang C.-W., Kumar S. Vinculin tension distributions of individual stress fibers within cell-matrix adhesions. J. Cell Sci. 2013, 126:3021-3030. 10.1242/jcs.119032.
    • (2013) J. Cell Sci. , vol.126 , pp. 3021-3030
    • Chang, C.-W.1    Kumar, S.2
  • 50
    • 0035479910 scopus 로고    scopus 로고
    • Assembly and mechanosensory function of focal contacts
    • Geiger B., Bershadsky A. Assembly and mechanosensory function of focal contacts. Curr. Opin. Cell Biol. 2001, 13:584-592.
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 584-592
    • Geiger, B.1    Bershadsky, A.2
  • 51
    • 37349005914 scopus 로고    scopus 로고
    • Fibroblast adaptation and stiffness matching to soft elastic substrates
    • Solon J., Levental I., Sengupta K., Georges P.C., Janmey P.A. Fibroblast adaptation and stiffness matching to soft elastic substrates. Biophys. J. 2007, 93:4453-4461. 10.1529/biophysj.106.101386.
    • (2007) Biophys. J. , vol.93 , pp. 4453-4461
    • Solon, J.1    Levental, I.2    Sengupta, K.3    Georges, P.C.4    Janmey, P.A.5
  • 52
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • Pelham R.J., Wang Y. Cell locomotion and focal adhesions are regulated by substrate flexibility. PNAS 1997, 94:13661-13665.
    • (1997) PNAS , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Wang, Y.2
  • 53
    • 0031017220 scopus 로고    scopus 로고
    • Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    • Maniotis A.J., Chen C.S., Ingber D.E. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. PNAS 1997, 94:849-854.
    • (1997) PNAS , vol.94 , pp. 849-854
    • Maniotis, A.J.1    Chen, C.S.2    Ingber, D.E.3
  • 54
    • 71849098437 scopus 로고    scopus 로고
    • Tissue motion and strain in the human brain assessed by intraoperative ultrasound in glioma patients
    • Selbekk T., Brekken R., Solheim O., Lydersen S., Hernes T.A.N., et al. Tissue motion and strain in the human brain assessed by intraoperative ultrasound in glioma patients. Ultrasound Med. Biol. 2010, 36:2-10. 10.1016/j.ultrasmedbio.2009.05.007.
    • (2010) Ultrasound Med. Biol. , vol.36 , pp. 2-10
    • Selbekk, T.1    Brekken, R.2    Solheim, O.3    Lydersen, S.4    Hernes, T.A.N.5
  • 55
    • 34249097683 scopus 로고    scopus 로고
    • Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation
    • Elkin B.S., Azeloglu E.U., Costa K.D., Morrison B. Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation. J. Neurotrauma 2007, 24:812-822. 10.1089/neu.2006.0169.
    • (2007) J. Neurotrauma , vol.24 , pp. 812-822
    • Elkin, B.S.1    Azeloglu, E.U.2    Costa, K.D.3    Morrison, B.4
  • 56
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • Lefranc F., Brotchi J., Kiss R. Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J. Clin. Oncol. 2005, 23:2411-2422. 10.1200/JCO.2005.03.089.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 57
    • 84965830225 scopus 로고
    • Structural development in gliomas
    • Scherer H. Structural development in gliomas. Am. J. Cancer 1938, 34:333-348.
    • (1938) Am. J. Cancer , vol.34 , pp. 333-348
    • Scherer, H.1
  • 58
    • 0001826365 scopus 로고
    • The forms of growth in gliomas and their practical significance
    • Scherer H.J. The forms of growth in gliomas and their practical significance. Brain 1940, 63:1-35. 10.1093/brain/63.1.1.
    • (1940) Brain , vol.63 , pp. 1-35
    • Scherer, H.J.1
  • 59
    • 0033028075 scopus 로고    scopus 로고
    • Astrocytoma adhesion to extracellular matrix: functional significance of integrin and focal adhesion kinase expression
    • Rutka J.T., Muller M., Hubbard S.L., Forsdike J., Dirks P.B., et al. Astrocytoma adhesion to extracellular matrix: functional significance of integrin and focal adhesion kinase expression. J. Neuropathol. Exp. Neurol. 1999, 58:198-209.
    • (1999) J. Neuropathol. Exp. Neurol. , vol.58 , pp. 198-209
    • Rutka, J.T.1    Muller, M.2    Hubbard, S.L.3    Forsdike, J.4    Dirks, P.B.5
  • 60
    • 0035542984 scopus 로고    scopus 로고
    • Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features
    • Belot N., Rorive S., Doyen I., Lefranc F., Bruyneel E., et al. Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features. Glia 2001, 36:375-390.
    • (2001) Glia , vol.36 , pp. 375-390
    • Belot, N.1    Rorive, S.2    Doyen, I.3    Lefranc, F.4    Bruyneel, E.5
  • 61
    • 0029929675 scopus 로고    scopus 로고
    • Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins
    • Friedlander D.R., Zagzag D., Shiff B., Cohen H., Allen J.C., et al. Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins. Cancer Res. 1996, 56:1939-1947.
    • (1996) Cancer Res. , vol.56 , pp. 1939-1947
    • Friedlander, D.R.1    Zagzag, D.2    Shiff, B.3    Cohen, H.4    Allen, J.C.5
  • 62
    • 0027753101 scopus 로고
    • Characterization of integrin receptors in normal and neoplastic human brain
    • Paulus W., Baur I., Schuppan D., Roggendorf W. Characterization of integrin receptors in normal and neoplastic human brain. Am. J. Pathol. 1993, 143:154-163.
    • (1993) Am. J. Pathol. , vol.143 , pp. 154-163
    • Paulus, W.1    Baur, I.2    Schuppan, D.3    Roggendorf, W.4
  • 63
    • 0031039632 scopus 로고    scopus 로고
    • Interstitial fluid pressure in intracranial tumours in patients and in rodents
    • Boucher Y., Salehi H., Witwer B., Harsh G.R., Jain R.K. Interstitial fluid pressure in intracranial tumours in patients and in rodents. Br. J. Cancer 1997, 75:829-836.
    • (1997) Br. J. Cancer , vol.75 , pp. 829-836
    • Boucher, Y.1    Salehi, H.2    Witwer, B.3    Harsh, G.R.4    Jain, R.K.5
  • 65
    • 84894380551 scopus 로고    scopus 로고
    • Mechanotransduction of fluid stresses governs 3D cell migration
    • (201316848)
    • Polacheck W.J., German A.E., Mammoto A., Ingber D.E., Kamm R.D. Mechanotransduction of fluid stresses governs 3D cell migration. PNAS 2014, (201316848). 10.1073/pnas.1316848111.
    • (2014) PNAS
    • Polacheck, W.J.1    German, A.E.2    Mammoto, A.3    Ingber, D.E.4    Kamm, R.D.5
  • 66
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen P.Y., Kesari S. Malignant gliomas in adults. N. Engl. J. Med. 2008, 359:492-507. 10.1056/NEJMra0708126.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 67
    • 26944437515 scopus 로고    scopus 로고
    • PDGFRbeta+perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
    • Song S., Ewald A.J., Stallcup W., Werb Z., Bergers G. PDGFRbeta+perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat. Cell Biol. 2005, 7:870-879. 10.1038/ncb1288.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 870-879
    • Song, S.1    Ewald, A.J.2    Stallcup, W.3    Werb, Z.4    Bergers, G.5
  • 68
    • 18644370120 scopus 로고    scopus 로고
    • The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours
    • Chekenya M., Enger P.Ø., Thorsen F., Tysnes B.B., Al-Sarraj S., et al. The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours. Neuropathol. Appl. Neurobiol. 2002, 28:367-380.
    • (2002) Neuropathol. Appl. Neurobiol. , vol.28 , pp. 367-380
    • Chekenya, M.1    Enger, P.Ø.2    Thorsen, F.3    Tysnes, B.B.4    Al-Sarraj, S.5
  • 69
    • 0036962461 scopus 로고    scopus 로고
    • Expression of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1 in human brain tumors and their involvement in glial proliferation in vitro
    • Barbero S., Bajetto A., Bonavia R., Porcile C., Piccioli P., et al. Expression of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1 in human brain tumors and their involvement in glial proliferation in vitro. Ann. N. Y. Acad. Sci. 2002, 973:60-69.
    • (2002) Ann. N. Y. Acad. Sci. , vol.973 , pp. 60-69
    • Barbero, S.1    Bajetto, A.2    Bonavia, R.3    Porcile, C.4    Piccioli, P.5
  • 70
    • 36048994736 scopus 로고    scopus 로고
    • Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment
    • Hoelzinger D.B., Demuth T., Berens M.E. Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J. Natl. Cancer Inst. 2007, 99:1583-1593. 10.1093/jnci/djm187.
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 1583-1593
    • Hoelzinger, D.B.1    Demuth, T.2    Berens, M.E.3
  • 71
    • 34147165551 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration
    • Emdad L., Sarkar D., Su Z.-Z., Lee S.-G., Kang D.-C., et al. Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration. Pharmacol. Ther. 2007, 114:155-170. 10.1016/j.pharmthera.2007.01.010.
    • (2007) Pharmacol. Ther. , vol.114 , pp. 155-170
    • Emdad, L.1    Sarkar, D.2    Su, Z.-Z.3    Lee, S.-G.4    Kang, D.-C.5
  • 72
    • 0033959917 scopus 로고    scopus 로고
    • Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma
    • Rempel S.A., Dudas S., Ge S., Gutiérrez J.A. Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma. Clin. Cancer Res. 2000, 6:102-111.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 102-111
    • Rempel, S.A.1    Dudas, S.2    Ge, S.3    Gutiérrez, J.A.4
  • 73
    • 0037147223 scopus 로고    scopus 로고
    • CXCR4 is a major chemokine receptor on glioma cells and mediates their survival
    • Zhou Y., Larsen P.H., Hao C., Yong V.W. CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J. Biol. Chem. 2002, 277:49481-49487. 10.1074/jbc.M206222200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49481-49487
    • Zhou, Y.1    Larsen, P.H.2    Hao, C.3    Yong, V.W.4
  • 74
    • 0029862967 scopus 로고    scopus 로고
    • Astrocyte-astrocytoma cell line interactions in culture
    • Lal P.G., Ghirnikar R.S., Eng L.F. Astrocyte-astrocytoma cell line interactions in culture. J. Neurosci. Res. 1996, 44:216-222. 10.1002/(SICI)1097-4547(19960501)44:3<216::AID-JNR2>3.0.CO;2-J.
    • (1996) J. Neurosci. Res. , vol.44 , pp. 216-222
    • Lal, P.G.1    Ghirnikar, R.S.2    Eng, L.F.3
  • 76
    • 0038719646 scopus 로고    scopus 로고
    • Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade
    • Le D.M., Besson A., Fogg D.K., Choi K.-S., Waisman D.M., et al. Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade. J. Neurosci. 2003, 23:4034-4043.
    • (2003) J. Neurosci. , vol.23 , pp. 4034-4043
    • Le, D.M.1    Besson, A.2    Fogg, D.K.3    Choi, K.-S.4    Waisman, D.M.5
  • 77
    • 34648821254 scopus 로고    scopus 로고
    • Making a tumour's bed: glioblastoma stem cells and the vascular niche
    • Gilbertson R.J., Rich J.N. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat. Rev. Cancer 2007, 7:733-736. 10.1038/nrc2246.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 733-736
    • Gilbertson, R.J.1    Rich, J.N.2
  • 78
    • 50849113768 scopus 로고    scopus 로고
    • Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
    • Mirzadeh Z., Merkle F.T., Soriano-Navarro M., Garcia-Verdugo J.M., Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 2008, 3:265-278. 10.1016/j.stem.2008.07.004.
    • (2008) Cell Stem Cell , vol.3 , pp. 265-278
    • Mirzadeh, Z.1    Merkle, F.T.2    Soriano-Navarro, M.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 79
    • 50849142558 scopus 로고    scopus 로고
    • Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions
    • Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.-M., et al. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3:289-300. 10.1016/j.stem.2008.07.026.
    • (2008) Cell Stem Cell , vol.3 , pp. 289-300
    • Shen, Q.1    Wang, Y.2    Kokovay, E.3    Lin, G.4    Chuang, S.-M.5
  • 80
  • 81
    • 39449135834 scopus 로고    scopus 로고
    • PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
    • Hambardzumyan D., Becher O.J., Rosenblum M.K., Pandolfi P.P., Manova-Todorova K., et al. PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev. 2008, 22:436-448. 10.1101/gad.1627008.
    • (2008) Genes Dev. , vol.22 , pp. 436-448
    • Hambardzumyan, D.1    Becher, O.J.2    Rosenblum, M.K.3    Pandolfi, P.P.4    Manova-Todorova, K.5
  • 82
    • 33748051406 scopus 로고    scopus 로고
    • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
    • Bao S., Wu Q., Sathornsumetee S., Hao Y., Li Z., et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 2006, 66:7843-7848. 10.1158/0008-5472.CAN-06-1010.
    • (2006) Cancer Res. , vol.66 , pp. 7843-7848
    • Bao, S.1    Wu, Q.2    Sathornsumetee, S.3    Hao, Y.4    Li, Z.5
  • 83
    • 33646533333 scopus 로고    scopus 로고
    • Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis
    • Farin A., Suzuki S.O., Weiker M., Goldman J.E., Bruce J.N., et al. Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis. Glia 2006, 53:799-808. 10.1002/glia.20334.
    • (2006) Glia , vol.53 , pp. 799-808
    • Farin, A.1    Suzuki, S.O.2    Weiker, M.3    Goldman, J.E.4    Bruce, J.N.5
  • 84
    • 75349091751 scopus 로고    scopus 로고
    • Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
    • Charles N., Ozawa T., Squatrito M., Bleau A.-M., Brennan C.W., et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell 2010, 6:141-152. 10.1016/j.stem.2010.01.001.
    • (2010) Cell Stem Cell , vol.6 , pp. 141-152
    • Charles, N.1    Ozawa, T.2    Squatrito, M.3    Bleau, A.-M.4    Brennan, C.W.5
  • 85
    • 84890254301 scopus 로고    scopus 로고
    • Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche
    • Infanger D.W., Cho Y., Lopez B.S., Mohanan S., Liu S.C., et al. Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche. Cancer Res. 2013, 73:7079-7089. 10.1158/0008-5472.CAN-13-1355.
    • (2013) Cancer Res. , vol.73 , pp. 7079-7089
    • Infanger, D.W.1    Cho, Y.2    Lopez, B.S.3    Mohanan, S.4    Liu, S.C.5
  • 86
    • 78650153633 scopus 로고    scopus 로고
    • Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
    • Ricci-Vitiani L., Pallini R., Biffoni M., Todaro M., Invernici G., et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010, 468:824-828. 10.1038/nature09557.
    • (2010) Nature , vol.468 , pp. 824-828
    • Ricci-Vitiani, L.1    Pallini, R.2    Biffoni, M.3    Todaro, M.4    Invernici, G.5
  • 87
    • 79952721477 scopus 로고    scopus 로고
    • Transdifferentiation of glioblastoma cells into vascular endothelial cells
    • Soda Y., Marumoto T., Friedmann-Morvinski D., Soda M., Liu F., et al. Transdifferentiation of glioblastoma cells into vascular endothelial cells. PNAS 2011, 108(11):4274-4280.
    • (2011) PNAS , vol.108 , Issue.11 , pp. 4274-4280
    • Soda, Y.1    Marumoto, T.2    Friedmann-Morvinski, D.3    Soda, M.4    Liu, F.5
  • 88
    • 78650098659 scopus 로고    scopus 로고
    • Glioblastoma stem-like cells give rise to tumour endothelium
    • Wang R., Chadalavada K., Wilshire J., Kowalik U., Hovinga K.E., et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 2010, 468:829-833. 10.1038/nature09624.
    • (2010) Nature , vol.468 , pp. 829-833
    • Wang, R.1    Chadalavada, K.2    Wilshire, J.3    Kowalik, U.4    Hovinga, K.E.5
  • 91
    • 0036946575 scopus 로고    scopus 로고
    • Microglia promote glioma migration
    • Bettinger I., Thanos S., Paulus W. Microglia promote glioma migration. Acta Neuropathol. 2002, 103:351-355. 10.1007/s00401-001-0472-x.
    • (2002) Acta Neuropathol. , vol.103 , pp. 351-355
    • Bettinger, I.1    Thanos, S.2    Paulus, W.3
  • 95
    • 0028858363 scopus 로고
    • Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro
    • Koochekpour S., Pilkington G.J., Merzak A. Hyaluronic acid/CD44H interaction induces cell detachment and stimulates migration and invasion of human glioma cells in vitro. Int. J. Cancer 1995, 63:450-454.
    • (1995) Int. J. Cancer , vol.63 , pp. 450-454
    • Koochekpour, S.1    Pilkington, G.J.2    Merzak, A.3
  • 96
    • 0033601769 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter
    • Belien A.T.J., Paganetti P.A., Schwab M.E. Membrane-type 1 matrix metalloprotease (MT1-MMP) enables invasive migration of glioma cells in central nervous system white matter. J. Cell Biol. 1999, 144:373-384. 10.1083/jcb.144.2.373.
    • (1999) J. Cell Biol. , vol.144 , pp. 373-384
    • Belien, A.T.J.1    Paganetti, P.A.2    Schwab, M.E.3
  • 97
    • 33644529130 scopus 로고    scopus 로고
    • Capturing complex 3D tissue physiology in vitro
    • Griffith L.G., Swartz M.A. Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 2006, 7:211-224. 10.1038/nrm1858.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 211-224
    • Griffith, L.G.1    Swartz, M.A.2
  • 98
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • Yamada K.M., Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 2007, 130:601-610. 10.1016/j.cell.2007.08.006.
    • (2007) Cell , vol.130 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 99
    • 79957534572 scopus 로고    scopus 로고
    • Targeting hypoxia in cancer therapy
    • Wilson W.R., Hay M.P. Targeting hypoxia in cancer therapy. Nat. Rev. Cancer 2011, 11:393-410. 10.1038/nrc3064.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 393-410
    • Wilson, W.R.1    Hay, M.P.2
  • 101
    • 0033917881 scopus 로고    scopus 로고
    • Cell movement is guided by the rigidity of the substrate
    • Lo C.-M., Wang H.-B., Dembo M., Wang Y. Cell movement is guided by the rigidity of the substrate. Biophys. J. 2000, 79:144-152. 10.1016/S0006-3495(00)76279-5.
    • (2000) Biophys. J. , vol.79 , pp. 144-152
    • Lo, C.-M.1    Wang, H.-B.2    Dembo, M.3    Wang, Y.4
  • 103
    • 0347319161 scopus 로고    scopus 로고
    • Substrate compliance versus ligand density in cell on gel responses
    • Engler A., Bacakova L., Newman C., Hategan A., Griffin M., et al. Substrate compliance versus ligand density in cell on gel responses. Biophys. J. 2004, 86:617-628.
    • (2004) Biophys. J. , vol.86 , pp. 617-628
    • Engler, A.1    Bacakova, L.2    Newman, C.3    Hategan, A.4    Griffin, M.5
  • 104
    • 34347205288 scopus 로고    scopus 로고
    • Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis
    • Johnson K.R., Leight J.L., Weaver V.M. Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods Cell Biol. 2007, 83:547-583. 10.1016/s0091-679x(07)83023-8.
    • (2007) Methods Cell Biol. , vol.83 , pp. 547-583
    • Johnson, K.R.1    Leight, J.L.2    Weaver, V.M.3
  • 105
    • 19944428596 scopus 로고    scopus 로고
    • Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
    • Yeung T., Georges P.C., Flanagan L.A., Marg B., Ortiz M., et al. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton 2005, 60:24-34. 10.1002/cm.20041.
    • (2005) Cell Motil. Cytoskeleton , vol.60 , pp. 24-34
    • Yeung, T.1    Georges, P.C.2    Flanagan, L.A.3    Marg, B.4    Ortiz, M.5
  • 106
    • 66249100268 scopus 로고    scopus 로고
    • The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells
    • Ulrich T.A., de Juan Pardo E.M., Kumar S. The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res. 2009, 69:4167-4174. 10.1158/0008-5472.CAN-08-4859.
    • (2009) Cancer Res. , vol.69 , pp. 4167-4174
    • Ulrich, T.A.1    de Juan Pardo, E.M.2    Kumar, S.3
  • 107
    • 77949531329 scopus 로고    scopus 로고
    • Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology
    • Sen S., Dong M.M., Kumar S. Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS ONE 2009, 4:e8427. 10.1371/journal.pone.0008427.
    • (2009) PLoS ONE , vol.4 , pp. e8427
    • Sen, S.1    Dong, M.M.2    Kumar, S.3
  • 108
    • 84863571674 scopus 로고    scopus 로고
    • Contributions of talin-1 to glioma cell-matrix tensional homeostasis
    • Sen S., Ng W.P., Kumar S. Contributions of talin-1 to glioma cell-matrix tensional homeostasis. J. R. Soc. Interface 2011, 9(71):1311-1317.
    • (2011) J. R. Soc. Interface , vol.9 , Issue.71 , pp. 1311-1317
    • Sen, S.1    Ng, W.P.2    Kumar, S.3
  • 109
    • 84863048761 scopus 로고    scopus 로고
    • A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodeling
    • MacKay J., Keung A., Kumar S. A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodeling. Biophys. J. 2012, 102:434-442. 10.1016/j.bpj.2011.12.048.
    • (2012) Biophys. J. , vol.102 , pp. 434-442
    • MacKay, J.1    Keung, A.2    Kumar, S.3
  • 111
    • 80051821707 scopus 로고    scopus 로고
    • Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform
    • Ananthanarayanan B., Kim Y., Kumar S. Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform. Biomaterials 2011, 32:7913-7923. 10.1016/j.biomaterials.2011.07.005.
    • (2011) Biomaterials , vol.32 , pp. 7913-7923
    • Ananthanarayanan, B.1    Kim, Y.2    Kumar, S.3
  • 112
    • 77956318381 scopus 로고    scopus 로고
    • Mechanical regulation of cell function with geometrically modulated elastomeric substrates
    • Fu J., Wang Y.-K., Yang M.T., Desai R.A., Yu X., et al. Mechanical regulation of cell function with geometrically modulated elastomeric substrates. Nat. Methods 2010, 7:733-736. 10.1038/nmeth.1487.
    • (2010) Nat. Methods , vol.7 , pp. 733-736
    • Fu, J.1    Wang, Y.-K.2    Yang, M.T.3    Desai, R.A.4    Yu, X.5
  • 113
  • 114
    • 84857198896 scopus 로고    scopus 로고
    • Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens
    • Ivkovic S., Beadle C., Noticewala S., Massey S.C., Swanson K.R., et al. Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens. Mol. Biol. Cell 2012, 23:533-542. 10.1091/mbc.E11-01-0039.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 533-542
    • Ivkovic, S.1    Beadle, C.2    Noticewala, S.3    Massey, S.C.4    Swanson, K.R.5
  • 115
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman E. Taking cell-matrix adhesions to the third dimension. Science 2001, 294:1708-1712. 10.1126/science.1064829.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1
  • 116
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: a dynamic niche in cancer progression
    • Lu P., Weaver V.M., Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J. Cell Biol. 2012, 196:395-406. 10.1083/jcb.201102147.
    • (2012) J. Cell Biol. , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 117
    • 0043164760 scopus 로고    scopus 로고
    • Measuring the mechanical stress induced by an expanding multicellular tumor system: a case study
    • Gordon V.D., Valentine M.T., Gardel M.L., Andor-Ard√≥ D., Dennison S., et al. Measuring the mechanical stress induced by an expanding multicellular tumor system: a case study. Exp. Cell Res. 2003, 289:58-66. 10.1016/S0014-4827(03)00256-8.
    • (2003) Exp. Cell Res. , vol.289 , pp. 58-66
    • Gordon, V.D.1    Valentine, M.T.2    Gardel, M.L.3    Andor-Ard, D.4    Dennison, S.5
  • 118
    • 33749425398 scopus 로고    scopus 로고
    • The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors
    • Hegedus B., Marga F., Jakab K., Sharpe-Timms K.L., Forgacs G. The interplay of cell-cell and cell-matrix interactions in the invasive properties of brain tumors. Biophys. J. 2006, 91:2708-2716. 10.1529/biophysj.105.077834.
    • (2006) Biophys. J. , vol.91 , pp. 2708-2716
    • Hegedus, B.1    Marga, F.2    Jakab, K.3    Sharpe-Timms, K.L.4    Forgacs, G.5
  • 119
    • 57349179996 scopus 로고    scopus 로고
    • Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence
    • Kim H.D., Guo T.W., Wu A.P., Wells A., Gertler F.B., et al. Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence. Mol. Biol. Cell 2008, 19:4249-4259. 10.1091/mbc.E08-05-0501.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4249-4259
    • Kim, H.D.1    Guo, T.W.2    Wu, A.P.3    Wells, A.4    Gertler, F.B.5
  • 120
    • 77953024602 scopus 로고    scopus 로고
    • Pore size variable type I collagen gels and their interaction with glioma cells
    • Yang Y., Motte S., Kaufman L.J. Pore size variable type I collagen gels and their interaction with glioma cells. Biomaterials 2010, 31:5678-5688. 10.1016/j.biomaterials.2010.03.039.
    • (2010) Biomaterials , vol.31 , pp. 5678-5688
    • Yang, Y.1    Motte, S.2    Kaufman, L.J.3
  • 121
    • 33645791896 scopus 로고    scopus 로고
    • In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
    • Thorne R.G., Nicholson C. In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:5567-5572. 10.1073/pnas.0509425103.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 5567-5572
    • Thorne, R.G.1    Nicholson, C.2
  • 122
    • 84861714640 scopus 로고    scopus 로고
    • Designing cell-compatible hydrogels for biomedical applications
    • Seliktar D. Designing cell-compatible hydrogels for biomedical applications. Science 2012, 336:1124-1128. 10.1126/science.1214804.
    • (2012) Science , vol.336 , pp. 1124-1128
    • Seliktar, D.1
  • 123
    • 19644367664 scopus 로고    scopus 로고
    • Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
    • Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat. Biotechnol. 2005, 23:47-55. 10.1038/nbt1055.
    • (2005) Nat. Biotechnol. , vol.23 , pp. 47-55
    • Lutolf, M.P.1    Hubbell, J.A.2
  • 124
    • 73249141139 scopus 로고    scopus 로고
    • Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices
    • Ulrich T.A., Jain A., Tanner K., MacKay J.L., Kumar S. Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices. Biomaterials 2010, 31:1875-1884. 10.1016/j.biomaterials.2009.10.047.
    • (2010) Biomaterials , vol.31 , pp. 1875-1884
    • Ulrich, T.A.1    Jain, A.2    Tanner, K.3    MacKay, J.L.4    Kumar, S.5
  • 125
    • 79957906219 scopus 로고    scopus 로고
    • Microscale mechanisms of agarose-induced disruption of collagen remodeling
    • Ulrich T.A., Lee T.G., Shon H.K., Moon D.W., Kumar S. Microscale mechanisms of agarose-induced disruption of collagen remodeling. Biomaterials 2011, 32:5633-5642. 10.1016/j.biomaterials.2011.04.045.
    • (2011) Biomaterials , vol.32 , pp. 5633-5642
    • Ulrich, T.A.1    Lee, T.G.2    Shon, H.K.3    Moon, D.W.4    Kumar, S.5
  • 126
    • 0042354574 scopus 로고    scopus 로고
    • Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
    • Sahai E., Marshall C.J. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat. Cell Biol. 2003, 5:711-719.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 711-719
    • Sahai, E.1    Marshall, C.J.2
  • 127
    • 0037455576 scopus 로고    scopus 로고
    • Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis
    • Wolf K., Mazo I., Leung H., Engelke K., von Andrian U.H., et al. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J. Cell Biol. 2003, 160:267-277. 10.1083/jcb.200209006.
    • (2003) J. Cell Biol. , vol.160 , pp. 267-277
    • Wolf, K.1    Mazo, I.2    Leung, H.3    Engelke, K.4    von Andrian, U.H.5
  • 128
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: diversity and escape mechanisms
    • Friedl P., Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 2003, 3:362-374. 10.1038/nrc1075.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 129
    • 72949084591 scopus 로고    scopus 로고
    • Spatially controlled hydrogel mechanics to modulate stem cell interactions
    • Marklein R.A., Burdick J.A. Spatially controlled hydrogel mechanics to modulate stem cell interactions. Soft Matter 2010, 6:136. 10.1039/b916933d.
    • (2010) Soft Matter , vol.6 , pp. 136
    • Marklein, R.A.1    Burdick, J.A.2
  • 130
    • 0037227965 scopus 로고    scopus 로고
    • CD44: from adhesion molecules to signalling regulators
    • Ponta H., Sherman L., Herrlich P.A. CD44: from adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell Biol. 2003, 4:33-45. 10.1038/nrm1004.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 131
    • 77950231070 scopus 로고    scopus 로고
    • CD44 attenuates activation of the Hippo signaling pathway and is a prime therapeutic target for glioblastoma
    • Xu Y., Stamenkovic I., Yu Q. CD44 attenuates activation of the Hippo signaling pathway and is a prime therapeutic target for glioblastoma. Cancer Res. 2010, 70:2455-2464. 10.1158/0008-5472.can-09-2505.
    • (2010) Cancer Res. , vol.70 , pp. 2455-2464
    • Xu, Y.1    Stamenkovic, I.2    Yu, Q.3
  • 133
    • 84856559148 scopus 로고    scopus 로고
    • Physical aspects of cell culture substrates: topography, roughness, and elasticity
    • Ross A.M., Jiang Z.X., Bastmeyer M., Lahann J. Physical aspects of cell culture substrates: topography, roughness, and elasticity. Small 2012, 8:336-355. 10.1002/smll.201100934.
    • (2012) Small , vol.8 , pp. 336-355
    • Ross, A.M.1    Jiang, Z.X.2    Bastmeyer, M.3    Lahann, J.4
  • 134
    • 84876678070 scopus 로고    scopus 로고
    • Tumor cell migration in complex microenvironments
    • Polacheck W.J., Zervantonakis I.K., Kamm R.D. Tumor cell migration in complex microenvironments. Cell. Mol. Life Sci. 2013, 70:1335-1356. 10.1007/s00018-012-1115-1.
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 1335-1356
    • Polacheck, W.J.1    Zervantonakis, I.K.2    Kamm, R.D.3
  • 135
    • 1642377826 scopus 로고    scopus 로고
    • Nanotopographical guidance of C6 glioma cell alignment and oriented growth
    • Zhu B.S., Zhang Q.Q., Lu Q.H., Xu Y.H., Yin J., et al. Nanotopographical guidance of C6 glioma cell alignment and oriented growth. Biomaterials 2004, 25:4215-4223. 10.1016/j.biomaterials.2003.11.020.
    • (2004) Biomaterials , vol.25 , pp. 4215-4223
    • Zhu, B.S.1    Zhang, Q.Q.2    Lu, Q.H.3    Xu, Y.H.4    Yin, J.5
  • 136
    • 84867325832 scopus 로고    scopus 로고
    • Microfabricated mimics of in vivo structural cues for the study of guided tumor cell migration
    • Gallego-Perez D., Higuita-Castro N., Denning L., DeJesus J., Dahl K., et al. Microfabricated mimics of in vivo structural cues for the study of guided tumor cell migration. Lab Chip 2012, 12:4424-4432. 10.1039/c2lc40726d.
    • (2012) Lab Chip , vol.12 , pp. 4424-4432
    • Gallego-Perez, D.1    Higuita-Castro, N.2    Denning, L.3    DeJesus, J.4    Dahl, K.5
  • 137
    • 84862998696 scopus 로고    scopus 로고
    • Independent regulation of tumor cell migration by matrix stiffness and confinement
    • Pathak A., Kumar S. Independent regulation of tumor cell migration by matrix stiffness and confinement. PNAS 2012, 109(26):10334-10339.
    • (2012) PNAS , vol.109 , Issue.26 , pp. 10334-10339
    • Pathak, A.1    Kumar, S.2
  • 138
    • 84892564175 scopus 로고    scopus 로고
    • Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration
    • Pathak A., Kumar S. Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration. Integr. Biol. (Camb.) 2013, 5:1067-1075. 10.1039/c3ib40017d.
    • (2013) Integr. Biol. (Camb.) , vol.5 , pp. 1067-1075
    • Pathak, A.1    Kumar, S.2
  • 139
    • 84884545390 scopus 로고    scopus 로고
    • Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression
    • Mammoto T., Jiang A., Jiang E., Panigrahy D., Kieran M.W., et al. Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression. Am. J. Pathol. 2013, 183(4):1293-1305.
    • (2013) Am. J. Pathol. , vol.183 , Issue.4 , pp. 1293-1305
    • Mammoto, T.1    Jiang, A.2    Jiang, E.3    Panigrahy, D.4    Kieran, M.W.5
  • 140
    • 33748331308 scopus 로고    scopus 로고
    • The mighty mouse: genetically engineered mouse models in cancer drug development
    • Sharpless N.E., Depinho R.A. The mighty mouse: genetically engineered mouse models in cancer drug development. Nat. Rev. Drug Discov. 2006, 5:741-754. 10.1038/nrd2110.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 741-754
    • Sharpless, N.E.1    Depinho, R.A.2
  • 141
    • 2042458747 scopus 로고    scopus 로고
    • Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
    • Johnson J.I., Decker S., Zaharevitz D., Rubinstein L.V., Venditti J.M., et al. Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials. Br. J. Cancer 2001, 84:1424-1431. 10.1054/bjoc.2001.1796.
    • (2001) Br. J. Cancer , vol.84 , pp. 1424-1431
    • Johnson, J.I.1    Decker, S.2    Zaharevitz, D.3    Rubinstein, L.V.4    Venditti, J.M.5
  • 142
    • 75749158184 scopus 로고    scopus 로고
    • Biomaterials offer cancer research the third dimension
    • Hutmacher D.W. Biomaterials offer cancer research the third dimension. Nat. Mater. 2010, 9:90-93. 10.1038/nmat2619.
    • (2010) Nat. Mater. , vol.9 , pp. 90-93
    • Hutmacher, D.W.1
  • 144
    • 34249880358 scopus 로고    scopus 로고
    • Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels
    • Liu Y., Shu X.Z., Prestwich G.D. Tumor engineering: orthotopic cancer models in mice using cell-loaded, injectable, cross-linked hyaluronan-derived hydrogels. Tissue Eng. 2007, 13:1091-1101.
    • (2007) Tissue Eng. , vol.13 , pp. 1091-1101
    • Liu, Y.1    Shu, X.Z.2    Prestwich, G.D.3
  • 145
    • 84861804698 scopus 로고    scopus 로고
    • Directed cell invasion and migration during metastasis
    • Bravo-Cordero J.J., Hodgson L., Condeelis J. Directed cell invasion and migration during metastasis. Curr. Opin. Cell Biol. 2012, 24:277-283. 10.1016/j.ceb.2011.12.004.
    • (2012) Curr. Opin. Cell Biol. , vol.24 , pp. 277-283
    • Bravo-Cordero, J.J.1    Hodgson, L.2    Condeelis, J.3
  • 146
    • 84876950650 scopus 로고    scopus 로고
    • Targeting tumor cell motility as a strategy against invasion and metastasis
    • Wells A., Grahovac J., Wheeler S., Ma B., Lauffenburger D. Targeting tumor cell motility as a strategy against invasion and metastasis. Trends Pharmacol. Sci. 2013, 34:283-289. 10.1016/j.tips.2013.03.001.
    • (2013) Trends Pharmacol. Sci. , vol.34 , pp. 283-289
    • Wells, A.1    Grahovac, J.2    Wheeler, S.3    Ma, B.4    Lauffenburger, D.5
  • 147
    • 84859000845 scopus 로고    scopus 로고
    • In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion
    • Hirata E., Yukinaga H., Kamioka Y., Arakawa Y., Miyamoto S., et al. In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion. J. Cell Sci. 2012, 125:858-868. 10.1242/jcs.089995.
    • (2012) J. Cell Sci. , vol.125 , pp. 858-868
    • Hirata, E.1    Yukinaga, H.2    Kamioka, Y.3    Arakawa, Y.4    Miyamoto, S.5
  • 148
    • 81855169565 scopus 로고    scopus 로고
    • Cancer invasion and the microenvironment: plasticity and reciprocity
    • Friedl P., Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 2011, 147:992-1009.
    • (2011) Cell , vol.147 , pp. 992-1009
    • Friedl, P.1    Alexander, S.2
  • 149
    • 75749146306 scopus 로고    scopus 로고
    • Plasticity of cell migration: a multiscale tuning model
    • Friedl P., Wolf K. Plasticity of cell migration: a multiscale tuning model. J. Cell Biol. 2009, 188:11-19. 10.1083/jcb.200909003.
    • (2009) J. Cell Biol. , vol.188 , pp. 11-19
    • Friedl, P.1    Wolf, K.2
  • 150
    • 84875580811 scopus 로고    scopus 로고
    • At the leading edge of three-dimensional cell migration
    • Petrie R.J., Yamada K.M. At the leading edge of three-dimensional cell migration. J. Cell Sci. 2013, 125(25):5917-5926.
    • (2013) J. Cell Sci. , vol.125 , Issue.25 , pp. 5917-5926
    • Petrie, R.J.1    Yamada, K.M.2
  • 151
    • 84877937046 scopus 로고    scopus 로고
    • Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue
    • Ruiz-Ontanon P., Orgaz J.L., Aldaz B., Elosegui-Artola A., Martino J., et al. Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue. Stem Cells 2013, 31:1075-1085. 10.1002/stem.1349.
    • (2013) Stem Cells , vol.31 , pp. 1075-1085
    • Ruiz-Ontanon, P.1    Orgaz, J.L.2    Aldaz, B.3    Elosegui-Artola, A.4    Martino, J.5
  • 152
    • 84864115184 scopus 로고    scopus 로고
    • ECT2 and RASAL2 mediate mesenchymal-amoeboid transition in human astrocytoma cells
    • Weeks A., Okolowsky N., Golbourn B., Ivanchuk S., Smith C., et al. ECT2 and RASAL2 mediate mesenchymal-amoeboid transition in human astrocytoma cells. Am. J. Pathol. 2012, 181:662-674. 10.1016/j.ajpath.2012.04.011.
    • (2012) Am. J. Pathol. , vol.181 , pp. 662-674
    • Weeks, A.1    Okolowsky, N.2    Golbourn, B.3    Ivanchuk, S.4    Smith, C.5
  • 153
    • 64049095782 scopus 로고    scopus 로고
    • Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
    • Yamazaki D., Kurisu S., Takenawa T. Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. Oncogene 2009, 28:1570-1583.
    • (2009) Oncogene , vol.28 , pp. 1570-1583
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 154
    • 84880028245 scopus 로고    scopus 로고
    • Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force
    • Wolf K., te Lindert M., Krause M., Alexander S., te Riet J., et al. Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J. Cell Biol. 2013, 201:1069-1084. 10.1083/jcb.201210152.
    • (2013) J. Cell Biol. , vol.201 , pp. 1069-1084
    • Wolf, K.1    te Lindert, M.2    Krause, M.3    Alexander, S.4    te Riet, J.5
  • 155
    • 0031471718 scopus 로고    scopus 로고
    • Regeneration of adult axons in white matter tracts of the central nervous system
    • Davies S.J.A., Fitch M.T., Memberg S.P., Hall A.K., Raisman G., et al. Regeneration of adult axons in white matter tracts of the central nervous system. Nature 1997, 390:680-683. 10.1038/37776.
    • (1997) Nature , vol.390 , pp. 680-683
    • Davies, S.J.A.1    Fitch, M.T.2    Memberg, S.P.3    Hall, A.K.4    Raisman, G.5
  • 156
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • Trapp B.D., Peterson J., Ransohoff R.M., Rudick R., Mörk S., et al. Axonal transection in the lesions of multiple sclerosis. N. Engl. J. Med. 1998, 338:278-285. 10.1056/NEJM199801293380502.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 278-285
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3    Rudick, R.4    Mörk, S.5
  • 157
    • 57649116340 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological models to assess demyelination and remyelination
    • Merrill J.E. In vitro and in vivo pharmacological models to assess demyelination and remyelination. Neuropsychopharmacology 2009, 34:55-73. 10.1038/npp.2008.145.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 55-73
    • Merrill, J.E.1
  • 158
    • 77949652722 scopus 로고    scopus 로고
    • Electrospinning: a fascinating fiber fabrication technique
    • Bhardwaj N., Kundu S.C. Electrospinning: a fascinating fiber fabrication technique. Biotechnol. Adv. 2010, 28:325-347. 10.1016/j.biotechadv.2010.01.004.
    • (2010) Biotechnol. Adv. , vol.28 , pp. 325-347
    • Bhardwaj, N.1    Kundu, S.C.2
  • 159
    • 56449118229 scopus 로고    scopus 로고
    • The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation
    • Christopherson G.T., Song H., Mao H.-Q. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials 2009, 30:556-564. 10.1016/j.biomaterials.2008.10.004.
    • (2009) Biomaterials , vol.30 , pp. 556-564
    • Christopherson, G.T.1    Song, H.2    Mao, H.-Q.3
  • 160
    • 36549084632 scopus 로고    scopus 로고
    • The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation
    • Chew S.Y., Mi R., Hoke A., Leong K.W. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 2008, 29:653-661. 10.1016/j.biomaterials.2007.10.025.
    • (2008) Biomaterials , vol.29 , pp. 653-661
    • Chew, S.Y.1    Mi, R.2    Hoke, A.3    Leong, K.W.4
  • 161
    • 44549088956 scopus 로고    scopus 로고
    • The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons
    • Corey J.M., Gertz C.C., Wang B.-S., Birrell L.K., Johnson S.L., et al. The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons. Acta Biomater. 2008, 4:863-875. 10.1016/j.actbio.2008.02.020.
    • (2008) Acta Biomater. , vol.4 , pp. 863-875
    • Corey, J.M.1    Gertz, C.C.2    Wang, B.-S.3    Birrell, L.K.4    Johnson, S.L.5
  • 162
    • 67849109814 scopus 로고    scopus 로고
    • Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering
    • Prabhakaran M.P., Venugopal J.R., Ramakrishna S. Mesenchymal stem cell differentiation to neuronal cells on electrospun nanofibrous substrates for nerve tissue engineering. Biomaterials 2009, 30:4996-5003. 10.1016/j.biomaterials.2009.05.057.
    • (2009) Biomaterials , vol.30 , pp. 4996-5003
    • Prabhakaran, M.P.1    Venugopal, J.R.2    Ramakrishna, S.3
  • 163
    • 72249090409 scopus 로고    scopus 로고
    • Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy
    • Johnson J., Nowicki M.O., Lee C.H., Chiocca E.A., Viapiano M.S., et al. Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy. Tissue Eng. Part C Methods 2009, 15:531-540. 10.1089/ten.tec.2008.0486.
    • (2009) Tissue Eng. Part C Methods , vol.15 , pp. 531-540
    • Johnson, J.1    Nowicki, M.O.2    Lee, C.H.3    Chiocca, E.A.4    Viapiano, M.S.5
  • 164
    • 84877046417 scopus 로고    scopus 로고
    • Mimicking white matter tract topography using core-shell electrospun nanofibers to examine migration of malignant brain tumors
    • Rao S.S., Nelson M.T., Xue R., DeJesus J.K., Viapiano M.S., et al. Mimicking white matter tract topography using core-shell electrospun nanofibers to examine migration of malignant brain tumors. Biomaterials 2013, 34:5181-5190. 10.1016/j.biomaterials.2013.03.069.
    • (2013) Biomaterials , vol.34 , pp. 5181-5190
    • Rao, S.S.1    Nelson, M.T.2    Xue, R.3    DeJesus, J.K.4    Viapiano, M.S.5
  • 165
    • 61349201437 scopus 로고    scopus 로고
    • In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells
    • Chen Z., Htay A., Dos Santos W., Gillies G.T., Fillmore H.L., et al. In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells. J. Neurooncol. 2009, 92:121-128. 10.1007/s11060-008-9742-y.
    • (2009) J. Neurooncol. , vol.92 , pp. 121-128
    • Chen, Z.1    Htay, A.2    Dos Santos, W.3    Gillies, G.T.4    Fillmore, H.L.5
  • 166
    • 0029983527 scopus 로고    scopus 로고
    • Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrier
    • Hurst R.D., Fritz I.B. Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrier. J. Cell. Physiol. 1996, 167:81-88. 10.1002/(SICI)1097-4652(199604)167:1<81::AID-JCP9>3.0.CO;2-8.
    • (1996) J. Cell. Physiol. , vol.167 , pp. 81-88
    • Hurst, R.D.1    Fritz, I.B.2
  • 167
    • 80052795862 scopus 로고    scopus 로고
    • Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
    • Zhu T.S., Costello M.A., Talsma C.E., Flack C.G., Crowley J.G., et al. Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res. 2011, 71:6061-6072. 10.1158/0008-5472.CAN-10-4269.
    • (2011) Cancer Res. , vol.71 , pp. 6061-6072
    • Zhu, T.S.1    Costello, M.A.2    Talsma, C.E.3    Flack, C.G.4    Crowley, J.G.5
  • 168
    • 0028783414 scopus 로고
    • A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis
    • Nehls V., Drenckhahn D. A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis. Microvasc. Res. 1995, 50:311-322. 10.1006/mvre.1995.1061.
    • (1995) Microvasc. Res. , vol.50 , pp. 311-322
    • Nehls, V.1    Drenckhahn, D.2
  • 169
    • 78650879483 scopus 로고    scopus 로고
    • Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responses
    • Leslie-Barbick J.E., Shen C., Chen C., West J.L. Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responses. Tissue Eng Part A 2011, 17:221-229. 10.1089/ten.TEA.2010.0202.
    • (2011) Tissue Eng Part A , vol.17 , pp. 221-229
    • Leslie-Barbick, J.E.1    Shen, C.2    Chen, C.3    West, J.L.4
  • 170
    • 84880346720 scopus 로고    scopus 로고
    • Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients
    • Baker B.M., Trappmann B., Stapleton S.C., Toro E., Chen C.S. Microfluidics embedded within extracellular matrix to define vascular architectures and pattern diffusive gradients. Lab Chip 2013, 13:3246-3252. 10.1039/C3LC50493J.
    • (2013) Lab Chip , vol.13 , pp. 3246-3252
    • Baker, B.M.1    Trappmann, B.2    Stapleton, S.C.3    Toro, E.4    Chen, C.S.5
  • 171
    • 84866355664 scopus 로고    scopus 로고
    • Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
    • Miller J.S., Stevens K.R., Yang M.T., Baker B.M., Nguyen D.-H.T., et al. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat. Mater. 2012, 11:768-774. 10.1038/nmat3357.
    • (2012) Nat. Mater. , vol.11 , pp. 768-774
    • Miller, J.S.1    Stevens, K.R.2    Yang, M.T.3    Baker, B.M.4    Nguyen, D.-H.T.5
  • 172
    • 84862197029 scopus 로고    scopus 로고
    • In vitro microvessels for the study of angiogenesis and thrombosis
    • Zheng Y., Chen J., Craven M., Choi N.W., Totorica S., et al. In vitro microvessels for the study of angiogenesis and thrombosis. PNAS 2012, 109:9342-9347. 10.1073/pnas.1201240109.
    • (2012) PNAS , vol.109 , pp. 9342-9347
    • Zheng, Y.1    Chen, J.2    Craven, M.3    Choi, N.W.4    Totorica, S.5
  • 173
    • 84876077149 scopus 로고    scopus 로고
    • A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer
    • Clark A.K., Taubenberger A.V., Taylor R.A., Niranjan B., Chea Z.Y., et al. A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer. Biomaterials 2013, 34:4777-4785. 10.1016/j.biomaterials.2013.03.005.
    • (2013) Biomaterials , vol.34 , pp. 4777-4785
    • Clark, A.K.1    Taubenberger, A.V.2    Taylor, R.A.3    Niranjan, B.4    Chea, Z.Y.5
  • 174
    • 79551583353 scopus 로고    scopus 로고
    • Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions
    • Kaji H., Camci-Unal G., Langer R., Khademhosseini A. Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions. Biochim. Biophys. Acta 2011, 1810:239-250. 10.1016/j.bbagen.2010.07.002.
    • (2011) Biochim. Biophys. Acta , vol.1810 , pp. 239-250
    • Kaji, H.1    Camci-Unal, G.2    Langer, R.3    Khademhosseini, A.4
  • 175
    • 0031081241 scopus 로고    scopus 로고
    • Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts
    • Bhatia S.N., Yarmush M.L., Toner M. Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts. J. Biomed. Mater. Res. 1997, 34:189-199.
    • (1997) J. Biomed. Mater. Res. , vol.34 , pp. 189-199
    • Bhatia, S.N.1    Yarmush, M.L.2    Toner, M.3
  • 176
    • 0034646334 scopus 로고    scopus 로고
    • Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems
    • Chiu D.T., Jeon N.L., Huang S., Kane R.S., Wargo C.J., et al. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:2408-2413. 10.1073/pnas.040562297.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 2408-2413
    • Chiu, D.T.1    Jeon, N.L.2    Huang, S.3    Kane, R.S.4    Wargo, C.J.5
  • 177
    • 0346497607 scopus 로고    scopus 로고
    • Microelectrochemical approach to induce local cell adhesion and growth on substrates
    • Kaji H., Kanada M., Oyamatsu D., Matsue T., Nishizawa M. Microelectrochemical approach to induce local cell adhesion and growth on substrates. Langmuir 2004, 20:16-19.
    • (2004) Langmuir , vol.20 , pp. 16-19
    • Kaji, H.1    Kanada, M.2    Oyamatsu, D.3    Matsue, T.4    Nishizawa, M.5
  • 178
    • 0035137731 scopus 로고    scopus 로고
    • Novel patterned cell coculture utilizing thermally responsive grafted polymer surfaces
    • Yamato M., Kwon O.H., Hirose M., Kikuchi A., Okano T. Novel patterned cell coculture utilizing thermally responsive grafted polymer surfaces. J. Biomed. Mater. Res. 2001, 55:137-140.
    • (2001) J. Biomed. Mater. Res. , vol.55 , pp. 137-140
    • Yamato, M.1    Kwon, O.H.2    Hirose, M.3    Kikuchi, A.4    Okano, T.5
  • 179
    • 47749117234 scopus 로고    scopus 로고
    • Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs
    • Du Y., Lo E., Ali S., Khademhosseini A. Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:9522-9527. 10.1073/pnas.0801866105.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 9522-9527
    • Du, Y.1    Lo, E.2    Ali, S.3    Khademhosseini, A.4
  • 180
    • 0037114401 scopus 로고    scopus 로고
    • Novel approach for achieving double-layered cell sheets co-culture: overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes
    • Harimoto M., Yamato M., Hirose M., Takahashi C., Isoi Y., et al. Novel approach for achieving double-layered cell sheets co-culture: overlaying endothelial cell sheets onto monolayer hepatocytes utilizing temperature-responsive culture dishes. J. Biomed. Mater. Res. 2002, 62:464-470. 10.1002/jbm.10228.
    • (2002) J. Biomed. Mater. Res. , vol.62 , pp. 464-470
    • Harimoto, M.1    Yamato, M.2    Hirose, M.3    Takahashi, C.4    Isoi, Y.5
  • 181
    • 39649115200 scopus 로고    scopus 로고
    • Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments
    • Wong A.P., Perez-Castillejos R., Christopher Love J., Whitesides G.M. Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments. Biomaterials 2008, 29:1853-1861. 10.1016/j.biomaterials.2007.12.044.
    • (2008) Biomaterials , vol.29 , pp. 1853-1861
    • Wong, A.P.1    Perez-Castillejos, R.2    Christopher Love, J.3    Whitesides, G.M.4
  • 182
    • 65549112285 scopus 로고    scopus 로고
    • High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research
    • Fernandes T.G., Diogo M.M., Clark D.S., Dordick J.S., Cabral J.M.S. High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research. Trends Biotechnol. 2009, 27:342-349. 10.1016/j.tibtech.2009.02.009.
    • (2009) Trends Biotechnol. , vol.27 , pp. 342-349
    • Fernandes, T.G.1    Diogo, M.M.2    Clark, D.S.3    Dordick, J.S.4    Cabral, J.M.S.5
  • 183
    • 46249111235 scopus 로고    scopus 로고
    • Functional immobilization of signaling proteins enables control of stem cell fate
    • Alberti K., Davey R.E., Onishi K., George S., Salchert K., et al. Functional immobilization of signaling proteins enables control of stem cell fate. Nat. Methods 2008, 5:645-650. 10.1038/nmeth.1222.
    • (2008) Nat. Methods , vol.5 , pp. 645-650
    • Alberti, K.1    Davey, R.E.2    Onishi, K.3    George, S.4    Salchert, K.5
  • 184
    • 3042825341 scopus 로고    scopus 로고
    • Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells
    • Anderson D.G., Levenberg S., Langer R. Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat. Biotechnol. 2004, 22:863-866. 10.1038/nbt981.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 863-866
    • Anderson, D.G.1    Levenberg, S.2    Langer, R.3
  • 185
    • 33751336911 scopus 로고    scopus 로고
    • Combinatorial protein display for the cell-based screening of biomaterials that direct neural stem cell differentiation
    • Nakajima M., Ishimuro T., Kato K., Ko I.-K., Hirata I., et al. Combinatorial protein display for the cell-based screening of biomaterials that direct neural stem cell differentiation. Biomaterials 2007, 28:1048-1060. 10.1016/j.biomaterials.2006.10.004.
    • (2007) Biomaterials , vol.28 , pp. 1048-1060
    • Nakajima, M.1    Ishimuro, T.2    Kato, K.3    Ko, I.-K.4    Hirata, I.5
  • 186
    • 84905467758 scopus 로고    scopus 로고
    • CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility
    • Kim Y., Kumar S. CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility. Mol. Cancer Res. 2014, 10.1158/1541-7786.MCR-13-0629.
    • (2014) Mol. Cancer Res.
    • Kim, Y.1    Kumar, S.2
  • 187
    • 84921654422 scopus 로고    scopus 로고
    • Interplay of matrix stiffness and protein tethering in stem cell differentiation
    • Wen, et al. Interplay of matrix stiffness and protein tethering in stem cell differentiation. Nat. Mater. 2014, 10.1038/nmat4051.
    • (2014) Nat. Mater.
    • Wen1
  • 188
    • 84896340580 scopus 로고    scopus 로고
    • Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility
    • Mackay J.L., Sood A., Kumar S. Three-dimensional patterning of multiple cell populations through orthogonal genetic control of cell motility. Soft Matter 2014, 10:2372-2380.
    • (2014) Soft Matter , vol.10 , pp. 2372-2380
    • Mackay, J.L.1    Sood, A.2    Kumar, S.3
  • 189
    • 84905442660 scopus 로고    scopus 로고
    • A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces
    • Rape A.D., Kumar S. A composite hydrogel platform for the dissection of tumor cell migration at tissue interfaces. Biomaterials 2014, 35(31):8846-8853.
    • (2014) Biomaterials , vol.35 , Issue.31 , pp. 8846-8853
    • Rape, A.D.1    Kumar, S.2


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