Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies

Archivum Immunologiae et Therapiae Experimentalis

Volumn 61, Issue 1, 2013, Pages 25-41

  Agnihotri, Sameer ^a   Burrell, Kelly E ^a   Wolf, Amparo ^a   Jalali, Sharzhad ^a   Hawkins, Cynthia ^a   Rutka, James T ^a   Zadeh, Gelareh ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Glioblastoma; Molecular genetics of glioma; Mouse models; Novel molecular targets

Indexed keywords

2 METHOXYESTRADIOL; 6 [4 (4 ETHYL 1 PIPERAZINYLMETHYL)PHENYL] 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; AFLIBERCEPT; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; BORTEZOMIB; CEDIRANIB; CETUXIMAB; DICHLOROACETIC ACID; ERLOTINIB; EVEROLIMUS; HYDROXYUREA; IMATINIB; IRINOTECAN; LAPATINIB; LONAFARNIB; PAZOPANIB; PERIFOSINE; RIDAFOROLIMUS; SORAFENIB; SUNITINIB; TAMOXIFEN; TANDUTINIB; TEMOZOLOMIDE; TEMSIROLIMUS; TIPIFARNIB; UNINDEXED DRUG; VANDETANIB; VATALANIB; VORINOSTAT;

AGE DISTRIBUTION; ANAEROBIC GLYCOLYSIS; APOPTOSIS; CANCER CLASSIFICATION; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER INVASION; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER STEM CELL; CANCER SURVIVAL; DRUG APPROVAL; DRUG EFFICACY; DRUG TARGETING; ETHNIC DIFFERENCE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GLIOBLASTOMA; HUMAN; IDH1 GENE; INCIDENCE; NONHUMAN; PATHOGENESIS; PERIPHERAL NEUROPATHY; PHARMACOLOGICAL BLOCKING; PROGRESSION FREE SURVIVAL; REVIEW; SURVIVAL RATE; TREATMENT RESPONSE; TUMOR SUPPRESSOR GENE;

ANIMALS; BRAIN NEOPLASMS; DISEASE MODELS, ANIMAL; GLIOBLASTOMA; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASM INVASIVENESS; PROTEOMICS;

EID: 84872612974     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-012-0203-0     Document Type: Review

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