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Volumn 31, Issue 6, 2013, Pages 1075-1085

Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue

Author keywords

Glioblastoma initiating cells; Integrin v 3; Invasion

Indexed keywords

BETA INTEGRIN; BETA3 INTEGRIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DIPEPTIDYL PEPTIDASE IV; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; NESTIN; NEUREXIN; NEUROPILIN 1; PROTEIN P27; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SOX2; VITRONECTIN RECEPTOR;

EID: 84877937046     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1349     Document Type: Article
Times cited : (82)

References (63)
  • 1
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • DOI 10.1200/JCO.2003.05.063
    • Giese A, Bjerkvig R, Berens ME et al. Cost of migration: Invasion of malignant gliomas and implications for treatment. J Clin Oncol 2003;21:1624-1636. (Pubitemid 46594118)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.8 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3    Westphal, M.4
  • 2
    • 0023225377 scopus 로고
    • Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms
    • Kelly PJ, Daumas-Duport C, Kispert DB et al. Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms. J Neurosurg 1987;66:865-874. (Pubitemid 17085708)
    • (1987) Journal of Neurosurgery , vol.66 , Issue.6 , pp. 865-874
    • Kelly, P.J.1    Daumas-Duport, C.2    Kispert, D.B.3
  • 3
    • 58149290094 scopus 로고    scopus 로고
    • CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities
    • Stevenson CB, Ehtesham M, McMillan KM et al. CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities. Neurosurgery 2008;63:560-569.
    • (2008) Neurosurgery , vol.63 , pp. 560-569
    • Stevenson, C.B.1    Ehtesham, M.2    McMillan, K.M.3
  • 4
    • 83055195105 scopus 로고    scopus 로고
    • Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor
    • Martirosyan NL, Cavalcanti DD, Eschbacher JM et al. Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor. J Neurosurg 2011;115:1131-1138.
    • (2011) J Neurosurg , vol.115 , pp. 1131-1138
    • Martirosyan, N.L.1    Cavalcanti, D.D.2    Eschbacher, J.M.3
  • 5
    • 0032975453 scopus 로고    scopus 로고
    • Graphic analysis of microscopic tumor cell infiltration proliferative potential, and vascular endothelial growth factor expression in an autopsy brain with glioblastoma
    • DOI 10.1016/S0090-3019(98)00056-1, PII S0090301998000561
    • Nagashima G, Suzuki R, Hokaku H et al. Graphic analysis of microscopic tumor cell infiltration, proliferative potential, and vascular endothelial growth factor expression in an autopsy brain with glioblastoma. Surg Neurol 1999;51:292-299. (Pubitemid 29135915)
    • (1999) Surgical Neurology , vol.51 , Issue.3 , pp. 292-299
    • Nagashima, G.1    Suzuki, R.2    Hokaku, H.3    Takahashi, M.4    Miyo, T.5    Asai, J.-I.6    Nakagawa, N.7    Fujimoto, T.8
  • 6
    • 45549093647 scopus 로고    scopus 로고
    • Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis
    • Eyler CE, Rich JN. Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol 2008;26:2839-2845.
    • (2008) J Clin Oncol , vol.26 , pp. 2839-2845
    • Eyler, C.E.1    Rich, J.N.2
  • 7
    • 77955300349 scopus 로고    scopus 로고
    • Residual tumor cells are unique cellular targets in glioblastoma
    • Glas M, Rath BH, Simon M et al. Residual tumor cells are unique cellular targets in glioblastoma. Ann Neurol 2010;68:264-269.
    • (2010) Ann Neurol , vol.68 , pp. 264-269
    • Glas, M.1    Rath, B.H.2    Simon, M.3
  • 8
    • 0345731237 scopus 로고    scopus 로고
    • Cell migration: Rho GTPases lead the way
    • DOI 10.1016/j.ydbio.2003.06.003
    • Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Biol 2004;265:23-32. (Pubitemid 38018819)
    • (2004) Developmental Biology , vol.265 , Issue.1 , pp. 23-32
    • Raftopoulou, M.1    Hall, A.2
  • 9
    • 84859000845 scopus 로고    scopus 로고
    • In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion
    • Hirata E, Yukinaga H, Kamioka Y et al. In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion. J Cell Sci 2012;125:858-868.
    • (2012) J Cell Sci , vol.125 , pp. 858-868
    • Hirata, E.1    Yukinaga, H.2    Kamioka, Y.3
  • 10
    • 79959916985 scopus 로고    scopus 로고
    • Glioblastoma motility occurs in the absence of actin polymer
    • Panopoulos A, Howell M, Fotedar R et al. Glioblastoma motility occurs in the absence of actin polymer. Mol Biol Cell 2011;22:2212-2220.
    • (2011) Mol Biol Cell , vol.22 , pp. 2212-2220
    • Panopoulos, A.1    Howell, M.2    Fotedar, R.3
  • 11
    • 57349179996 scopus 로고    scopus 로고
    • Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence
    • Kim HD, Guo TW, Wu AP et al. Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence. Mol Biol Cell 2008;19:4249-4259.
    • (2008) Mol Biol Cell , vol.19 , pp. 4249-4259
    • Kim, H.D.1    Guo, T.W.2    Wu, A.P.3
  • 12
    • 66249100268 scopus 로고    scopus 로고
    • The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells
    • Ulrich TA, de Juan Pardo EM, Kumar S. The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res 2009;69:4167-4174.
    • (2009) Cancer Res , vol.69 , pp. 4167-4174
    • Ulrich, T.A.1    De Juan Pardo, E.M.2    Kumar, S.3
  • 14
    • 40949099624 scopus 로고    scopus 로고
    • The protein phosphatase activity of PTEN regulates Src family kinases and controls glioma migration
    • DOI 10.1158/0008-5472.CAN-07-1182
    • Dey N, Crosswell HE, De P et al. The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration. Cancer Res 2008;68:1862-1871. (Pubitemid 351416572)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 1862-1871
    • Dey, N.1    Crosswell, H.E.2    Pradip, D.3    Parsons, R.4    Peng, Q.5    Jing, D.S.6    Durden, D.L.7
  • 15
    • 33646155963 scopus 로고    scopus 로고
    • Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha
    • Jiang G, Huang AH, Cai Y et al. Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha. Biophys J 2006;90:1804-1809.
    • (2006) Biophys J , vol.90 , pp. 1804-1809
    • Jiang, G.1    Huang, A.H.2    Cai, Y.3
  • 16
    • 1942466518 scopus 로고    scopus 로고
    • Kip1 modulates cell migration through the regulation of RhoA activation
    • DOI 10.1101/gad.1185504
    • Besson A, Gurian-West M, Schmidt A et al. p27Kip1 modulates cell migration through the regulation of RhoA activation. Genes Dev 2004;18:862-876. (Pubitemid 38529656)
    • (2004) Genes and Development , vol.18 , Issue.8 , pp. 862-876
    • Besson, A.1    Gurian-West, M.2    Schmidt, A.3    Hall, A.4    Roberts, J.M.5
  • 17
    • 80051800349 scopus 로고    scopus 로고
    • Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo
    • Nogueira L, Ruiz-Ontanon P, Vazquez-Barquero A et al. Blockade of the NFkappaB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo. Oncogene 2011;30:3537-3548.
    • (2011) Oncogene , vol.30 , pp. 3537-3548
    • Nogueira, L.1    Ruiz-Ontanon, P.2    Vazquez-Barquero, A.3
  • 18
    • 65549150903 scopus 로고    scopus 로고
    • Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
    • McCord AM, Jamal M, Shankavaram UT et al. Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol Cancer Res 2009;7:489-497.
    • (2009) Mol Cancer Res , vol.7 , pp. 489-497
    • McCord, A.M.1    Jamal, M.2    Shankavaram, U.T.3
  • 19
    • 73949090085 scopus 로고    scopus 로고
    • An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression
    • Trinidad EM, Ballesteros M, Zuloaga J et al. An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression. Blood 2009;114:5081-5090.
    • (2009) Blood , vol.114 , pp. 5081-5090
    • Trinidad, E.M.1    Ballesteros, M.2    Zuloaga, J.3
  • 21
    • 54549088877 scopus 로고    scopus 로고
    • Rac activation and inactivation control plasticity of tumor cell movement
    • Sanz-Moreno V, Gadea G, Ahn J et al. Rac activation and inactivation control plasticity of tumor cell movement. Cell 2008;135:510-523.
    • (2008) Cell , vol.135 , pp. 510-523
    • Sanz-Moreno, V.1    Gadea, G.2    Ahn, J.3
  • 22
    • 33646122464 scopus 로고    scopus 로고
    • Partial uniparental disomy: A recurrent genetic mechanism alternative to chromosomal deletion in malignant lymphoma
    • Nielaender I, Martin-Subero JI, Wagner F et al. Partial uniparental disomy: A recurrent genetic mechanism alternative to chromosomal deletion in malignant lymphoma. Leukemia 2006;20:904-905.
    • (2006) Leukemia , vol.20 , pp. 904-905
    • Nielaender, I.1    Martin-Subero, J.I.2    Wagner, F.3
  • 23
    • 47249113042 scopus 로고    scopus 로고
    • Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype
    • Roy S, Singh RP, Agarwal C et al. Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype. Cell Cycle 2008;7:1828-1835. (Pubitemid 351988749)
    • (2008) Cell Cycle , vol.7 , Issue.12 , pp. 1828-1835
    • Roy, S.1    Singh, R.P.2    Agarwal, C.3    Siriwardana, S.4    Sclafani, R.5    Agarwal, R.6
  • 24
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso OA, Chiariello M, Yu JC et al. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995;81:1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3
  • 26
    • 65749087298 scopus 로고    scopus 로고
    • Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
    • Laks DR, Masterman-Smith M, Visnyei K et al. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells 2009;27:980-987.
    • (2009) Stem Cells , vol.27 , pp. 980-987
    • Laks, D.R.1    Masterman-Smith, M.2    Visnyei, K.3
  • 29
    • 77956214387 scopus 로고    scopus 로고
    • Tumor-initiating cells are rare in many human tumors
    • Ishizawa K, Rasheed ZA, Karisch R et al. Tumor-initiating cells are rare in many human tumors. Cell Stem Cell 2010;7:279-282.
    • (2010) Cell Stem Cell , vol.7 , pp. 279-282
    • Ishizawa, K.1    Rasheed, Z.A.2    Karisch, R.3
  • 30
    • 77950502115 scopus 로고    scopus 로고
    • A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
    • Chen R, Nishimura MC, Bumbaca SM et al. A hierarchy of self-renewing tumor-initiating cell types in glioblastoma. Cancer Cell 2010;17:362-375.
    • (2010) Cancer Cell , vol.17 , pp. 362-375
    • Chen, R.1    Nishimura, M.C.2    Bumbaca, S.M.3
  • 31
    • 70349293691 scopus 로고    scopus 로고
    • Reduced proliferation and enhanced migration: Two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1
    • Evdokimova V, Tognon C, Ng T et al. Reduced proliferation and enhanced migration: Two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1. Cell Cycle 2009;8:2901-2906.
    • (2009) Cell Cycle , vol.8 , pp. 2901-2906
    • Evdokimova, V.1    Tognon, C.2    Ng, T.3
  • 34
    • 33747152561 scopus 로고    scopus 로고
    • Matrix Elasticity Directs Stem Cell Lineage Specification
    • DOI 10.1016/j.cell.2006.06.044, PII S0092867406009615
    • Engler AJ, Sen S, Sweeney HL et al. Matrix elasticity directs stem cell lineage specification. Cell 2006;126:677-689. (Pubitemid 44233625)
    • (2006) Cell , vol.126 , Issue.4 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 35
    • 0025185099 scopus 로고
    • Measurement of DNA content and nuclear pleomorphism in metastatic variants of the B16 murine melanoma and hamster lymphoma and its liver metastasis using image analysis techniques
    • Lakshmi MS, Sherbet GV. Measurement of DNA content and nuclear pleomorphism in metastatic variants of the B16 murine melanoma and hamster lymphoma and its liver metastasis using image analysis techniques. Clin Exp Metastasis 1990;8:553-566. (Pubitemid 20355469)
    • (1990) Clinical and Experimental Metastasis , vol.8 , Issue.6 , pp. 553-566
    • Lakshmi, M.S.1    Sherbet, G.V.2
  • 36
    • 81555209825 scopus 로고    scopus 로고
    • Nuclear atypia grading score is a useful prognostic factor in papillary gastric adenocarcinoma
    • Nakashima Y, Yao T, Hirahashi M et al. Nuclear atypia grading score is a useful prognostic factor in papillary gastric adenocarcinoma. Histopathology 2011;59:841-849.
    • (2011) Histopathology , vol.59 , pp. 841-849
    • Nakashima, Y.1    Yao, T.2    Hirahashi, M.3
  • 37
    • 0042354574 scopus 로고    scopus 로고
    • Differing modes for tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
    • DOI 10.1038/ncb1019
    • Sahai E, Marshall CJ. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 2003;5:711-719. (Pubitemid 36986778)
    • (2003) Nature Cell Biology , vol.5 , Issue.8 , pp. 711-719
    • Sahai, E.1    Marshall, C.J.2
  • 39
    • 64049095782 scopus 로고    scopus 로고
    • Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates
    • Yamazaki D, Kurisu S, Takenawa T. Involvement of Rac and Rho signaling in cancer cell motility in 3D substrates. Oncogene 2009;28:1570-1583.
    • (2009) Oncogene , vol.28 , pp. 1570-1583
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 40
    • 70349496205 scopus 로고    scopus 로고
    • Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction
    • Roca-Cusachs P, Gauthier NC, Del Rio A et al. Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction. Proc Natl Acad Sci USA 2009;106:16245-16250.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16245-16250
    • Roca-Cusachs, P.1    Gauthier, N.C.2    Del Rio, A.3
  • 41
    • 0026554217 scopus 로고
    • Affinity of integrins for damaged extracellular matrix: Alpha v beta 3 binds to denatured collagen type I through RGD sites
    • Davis GE. Affinity of integrins for damaged extracellular matrix: Alpha v beta 3 binds to denatured collagen type I through RGD sites. Biochem Biophys Res Commun 1992;182:1025-1031.
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 1025-1031
    • Davis, G.E.1
  • 42
    • 77957281923 scopus 로고    scopus 로고
    • Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion
    • Sato H, Takino T. Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion. Cancer Sci 2010;101:843-847.
    • (2010) Cancer Sci , vol.101 , pp. 843-847
    • Sato, H.1    Takino, T.2
  • 43
    • 80054710797 scopus 로고    scopus 로고
    • Cdc42 regulates extracellular matrix remodeling in three dimensions
    • Sipes NS, Feng Y, Guo F et al. Cdc42 regulates extracellular matrix remodeling in three dimensions. J Biol Chem 2011;286:36469-36477.
    • (2011) J Biol Chem , vol.286 , pp. 36469-36477
    • Sipes, N.S.1    Feng, Y.2    Guo, F.3
  • 44
    • 77950676582 scopus 로고    scopus 로고
    • p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling
    • Belletti B, Pellizzari I, Berton S et al. p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling. Mol Cell Biol 2010;30:2229-2240.
    • (2010) Mol Cell Biol , vol.30 , pp. 2229-2240
    • Belletti, B.1    Pellizzari, I.2    Berton, S.3
  • 45
    • 0000315614 scopus 로고    scopus 로고
    • Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA
    • Kranenburg O, Poland M, Gebbink M et al. Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA. J Cell Sci 1997;110:2417-2427. (Pubitemid 127699156)
    • (1997) Journal of Cell Science , vol.110 , Issue.19 , pp. 2417-2427
    • Kranenburg, O.1    Poland, M.2    Gebbink, M.3    Oomen, L.4    Moolenaar, W.H.5
  • 46
    • 32544443281 scopus 로고    scopus 로고
    • Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts
    • DOI 10.1523/JNEUROSCI.4209-05.2006
    • Woo S, Gomez TM. Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. J Neurosci 2006;26:1418-1428. (Pubitemid 43237012)
    • (2006) Journal of Neuroscience , vol.26 , Issue.5 , pp. 1418-1428
    • Woo, S.1    Gomez, T.M.2
  • 47
    • 34249097683 scopus 로고    scopus 로고
    • Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation
    • DOI 10.1089/neu.2006.0169
    • Elkin BS, Azeloglu EU, Costa KD et al. Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation. J Neurotrauma 2007;24:812-822. (Pubitemid 46799273)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.5 , pp. 812-822
    • Elkin, B.S.1    Azeloglu, E.U.2    Costa, K.D.3    Morrison III, B.4
  • 49
    • 67649240336 scopus 로고    scopus 로고
    • The vascular basement membrane as "soil" in brain metastasis
    • Carbonell WS, Ansorge O, Sibson N et al. The vascular basement membrane as "soil" in brain metastasis. PLoS One 2009;4:e5857.
    • (2009) PLoS One , vol.4
    • Carbonell, W.S.1    Ansorge, O.2    Sibson, N.3
  • 51
    • 0032487438 scopus 로고    scopus 로고
    • Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression
    • DOI 10.1083/jcb.143.1.267
    • Bourdoulous S, Orend G, MacKenna DA et al. Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression. J Cell Biol 1998;143:267-276. (Pubitemid 28480534)
    • (1998) Journal of Cell Biology , vol.143 , Issue.1 , pp. 267-276
    • Bourdoulous, S.1    Orend, G.2    MacKenna, D.A.3    Pasqualini, R.4    Ruoslahti, E.5
  • 52
    • 84861882390 scopus 로고    scopus 로고
    • The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility
    • Ahn J, Sanz-Moreno V, Marshall CJ. The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility. J Cell Sci 2012;125:1814-1826.
    • (2012) J Cell Sci , vol.125 , pp. 1814-1826
    • Ahn, J.1    Sanz-Moreno, V.2    Marshall, C.J.3
  • 53
    • 80053531542 scopus 로고    scopus 로고
    • The role of integrins in glioma biology and anti-glioma therapies
    • Tabatabai G, Tonn JC, Stupp R et al. The role of integrins in glioma biology and anti-glioma therapies. Curr Pharm Des 2011;17:2402-2410.
    • (2011) Curr Pharm des , vol.17 , pp. 2402-2410
    • Tabatabai, G.1    Tonn, J.C.2    Stupp, R.3
  • 55
    • 33644509197 scopus 로고    scopus 로고
    • Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity
    • Wu FY, Wang SE, Sanders ME et al. Reduction of cytosolic p27(Kip1) inhibits cancer cell motility, survival, and tumorigenicity. Cancer Res 2006;66:2162-2172.
    • (2006) Cancer Res , vol.66 , pp. 2162-2172
    • Wu, F.Y.1    Wang, S.E.2    Sanders, M.E.3
  • 56
    • 49849088123 scopus 로고    scopus 로고
    • p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis
    • Schiappacassi M, Lovat F, Canzonieri V et al. p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis. Mol Cancer Ther 2008;7:1164-1175.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1164-1175
    • Schiappacassi, M.1    Lovat, F.2    Canzonieri, V.3
  • 57
    • 84861535841 scopus 로고    scopus 로고
    • Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated
    • Ho B, Olson G, Figel S et al. Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated. J Biol Chem 2012;287:18656-18673.
    • (2012) J Biol Chem , vol.287 , pp. 18656-18673
    • Ho, B.1    Olson, G.2    Figel, S.3
  • 58
    • 77953546997 scopus 로고    scopus 로고
    • SNAI2/Slug promotes growth and invasion in human gliomas
    • Yang HW, Menon LG, Black PM et al. SNAI2/Slug promotes growth and invasion in human gliomas. BMC Cancer 2010;10:301.
    • (2010) BMC Cancer , vol.10 , pp. 301
    • Yang, H.W.1    Menon, L.G.2    Black, P.M.3
  • 59
    • 81355150792 scopus 로고    scopus 로고
    • Common DISC1 polymorphisms disrupt Wnt/GSK3beta signaling and brain development
    • Singh KK, De Rienzo G, Drane L et al. Common DISC1 polymorphisms disrupt Wnt/GSK3beta signaling and brain development. Neuron 2011;72:545-558.
    • (2011) Neuron , vol.72 , pp. 545-558
    • Singh, K.K.1    De Rienzo, G.2    Drane, L.3
  • 60
    • 84861810371 scopus 로고    scopus 로고
    • The oncogenic TBC domain protein USP6/TRE17 regulates cell migration and cytokinesis
    • Rueckert C, Haucke V. The oncogenic TBC domain protein USP6/TRE17 regulates cell migration and cytokinesis. Biol Cell 2012;104:22-33.
    • (2012) Biol Cell , vol.104 , pp. 22-33
    • Rueckert, C.1    Haucke, V.2
  • 61
    • 33846993355 scopus 로고    scopus 로고
    • The in vivo antitumoral effects of lipopolysaccharide against glioblastoma multiforme are mediated in part by Toll-like receptor 4
    • Chicoine MR, Zahner M, Won EK et al. The in vivo antitumoral effects of lipopolysaccharide against glioblastoma multiforme are mediated in part by Toll-like receptor 4. Neurosurgery 2007;60:372-380.
    • (2007) Neurosurgery , vol.60 , pp. 372-380
    • Chicoine, M.R.1    Zahner, M.2    Won, E.K.3
  • 62
    • 59649085331 scopus 로고    scopus 로고
    • Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway
    • Kleaveland B, Zheng X, Liu JJ et al. Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med 2009;15:169-176.
    • (2009) Nat Med , vol.15 , pp. 169-176
    • Kleaveland, B.1    Zheng, X.2    Liu, J.J.3
  • 63
    • 79952721477 scopus 로고    scopus 로고
    • Transdifferentiation of glioblastoma cells into vascular endothelial cells
    • Soda Y, Marumoto T, Friedmann-Morvinski D et al. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci USA 2011;108:4274-4280.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4274-4280
    • Soda, Y.1    Marumoto, T.2    Friedmann-Morvinski, D.3


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