Ape1 is dispensable for s-region cleavage but required for its repair in class switch recombination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 48, 2014, Pages 17242-17247

  Xu, Jianliang ^a   Husain, Afzal ^a   Hu, Wenjun ^a   Honjo, Tasuku ^a   Kobayashi, Maki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Class switch recombination |; Dna cleavage |; Dna synapse formation |; End processing; Somatic hypermutation |

Indexed keywords

AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); APEX1 PROTEIN, MOUSE; CARRIER PROTEIN; CELL CYCLE PROTEIN; CTIP PROTEIN, MOUSE; CYTIDINE DEAMINASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA BINDING PROTEIN; DNA LIGASE; IMMUNOGLOBULIN HEAVY CHAIN; MRE11A PROTEIN, MOUSE; MYC PROTEIN;

ANIMAL; B CELL LYMPHOMA; DNA DAMAGE; DNA REPAIR; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETICS; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PROTEIN TRANSPORT; RNA INTERFERENCE; SOMATIC HYPERMUTATION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CYTIDINE DEAMINASE; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-BINDING PROTEINS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOMA, B-CELL; MICE; MUTATION; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINATION, GENETIC; RNA INTERFERENCE; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 84914158812     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420221111     Document Type: Article

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