DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions

Journal of Experimental Medicine

Volumn 209, Issue 6, 2012, Pages 1075-1081

  Saribasak, Huseyin ^a,c   Maul, Robert W ^a   Cao, Zheng ^a   Yang, William W ^a   Schenten, Dominik ^b,d   Kracker, Sven ^b,e   Gearhart, Patricia J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SIFA UNIVERSITY   (Turkey)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; DNA POLYMERASE; DNA POLYMERASE ZETA; PROTEIN MSH2; PROTEIN MSH6; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENE MUTATION; GENETIC RECOMBINATION; HETEROZYGOSITY; IMMUNOGLOBULIN VARIABLE REGION; IN VIVO STUDY; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC HYPERMUTATION; TANDEM REPEAT;

ANIMALS; CELL DIVISION; DNA MISMATCH REPAIR; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; HETEROZYGOTE; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, MUTANT STRAINS; MUTATION; MUTS HOMOLOG 2 PROTEIN; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; URACIL-DNA GLYCOSIDASE;

EID: 84864309038     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20112234     Document Type: Article

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