WRN exonuclease activity is blocked by DNA termini harboring 3′ obstructive groups

Mechanisms of Ageing and Development

Volumn 128, Issue 3, 2007, Pages 259-266

  Harrigan, Jeanine A ^a   Fan, Jinshui ^a   Momand, Jamil ^b   Perrino, Fred W ^c   Bohr, Vilhelm A ^a   Wilson III, David M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

Author keywords

3 Damage repair; Exonuclease; Werner syndrome; WRN

Indexed keywords

CAMPTOTHECIN; DNA; EXONUCLEASE; OLIGONUCLEOTIDE; PHOSPHATE; PHOSPHOGLYCOLATE DERIVATIVE; PROTEIN APE1; PROTEIN P53; PROTEIN TREX1; REACTIVE OXYGEN METABOLITE; SINGLE STRANDED DNA; TYROSINE; UNCLASSIFIED DRUG; WERNER SYNDROME PROTEIN;

ARTICLE; CELL RESPIRATION; DNA MODIFICATION; DNA REPAIR; DNA STRAND BREAKAGE; DNA STRUCTURE; DNA SYNTHESIS; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; WERNER SYNDROME;

CELLS, CULTURED; DNA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; GENES, P53; GLYCOLATES; HUMANS; OLIGONUCLEOTIDES; OXIDATION-REDUCTION; PROTEINS; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; RECQ HELICASES; TYROSINE;

EID: 33846875447     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2006.12.005     Document Type: Article

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